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Added Value of Chemical Exchange-Dependent Saturation Transfer MRI for the Diagnosis of Dementia

Oh JH, Choi BG, Rhee HY, Lee JS, Lee KM, Park S, Cho AR, Ryu CW, Park KC, Kim EJ, Jahng GH

Objective: Chemical exchange-dependent saturation transfer (CEST) MRI is sensitive for detecting solid-like proteins and may detect changes in the levels of mobile proteins and peptides in tissues. The objective of...
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Magnetic Resonance Imaging: Historical Overview, Technical Developments, and Clinical Applications

Jahng GH, Park S, Ryu CW, Cho ZH

The authors congratulate the cerebrations for the 30 years of the Korean Society of Medical Physics (http://www.ksmp.or.kr/). The paper is published to recognize the anniversary. Geon-Ho Jahng invited Professor Z....
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The Role of Double Inversion Recovery Imaging in Acute Ischemic Stroke

Choi NY, Park S, Lee CM, Ryu CW, Jahng GH

PURPOSE: The purpose of this study was to investigate if double inversion recovery (DIR) imaging can have a role in the evaluation of brain ischemia, compared with diffusion-weighted imaging (DWI)...
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b0 Dependent Neuronal Activation in the Diffusion-Based Functional MRI

Kim HG, Jahng GH

PURPOSE: To develop a new diffusion-based functional MRI (fMRI) sequence to generate apparent diffusion coefficient (ADC) maps in single excitation and evaluate the contribution of b0 signal on neuronal changes. MATERIALS...
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Changes in the Laterality of Functional Connectivity Associated with Tinnitus: Resting-State fMRI Study

Shin Y, Ryu CW, Jahng GH, Park MS, Byun JY

PURPOSE: One of the suggested potential mechanisms of tinnitus is an alteration in perception in the neural auditory pathway. The aim of this study was to investigate the difference in...
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Assessment of the Cerebrospinal Fluid Effect on the Chemical Exchange Saturation Transfer Map Obtained from the Full Z-Spectrum in the Elderly Human Brain

Park S, Jang J, Oh JH, Ryu CW, Jahng GH

PURPOSE: With neurodegeneration, the signal intensity of the cerebrospinal fluid (CSF) in the brain increases. The objective of this study was to evaluate chemical exchange saturation transfer (CEST) signals with...
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Inter-Vendor and Inter-Session Reliability of Diffusion Tensor Imaging: Implications for Multicenter Clinical Imaging Studies

Min J, Park M, Choi JW, Jahng GH, Moon WJ

OBJECTIVE: To evaluate the inter-vendor and inter-session reliability of diffusion tensor imaging (DTI) and relevant parameters. MATERIALS AND METHODS: This prospective study included 10 healthy subjects (5 women and 5 men;...
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Preliminary Phantom Experiments to Map Amino Acids and Neurotransmitters Using MRI

Oh JH, Kim HG, Woo DC, Rhee SJ, Lee SY, Jahng GH

The objective of this study was to evaluate the chemical exchange saturation transfer (CEST) effect of amino acids and neurotransmitters, which exist in the human brain, depending on the concentration,...
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Gray Matter Volume Reductions Were Associated with TPH1 Polymorphisms in Depressive Disorder Patients with Suicidal Attempts

Lee SM, Lee S, Kang WS, Jahng GH, Park HJ, Kim SK, Park JK

OBJECTIVE: Structural changes of brain areas have been reported in depressive disorder and suicidal behavior (SB), in which TPH1 also has been known as a promising candidate gene. We investigated...
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Estimation of T2* Relaxation Time of Breast Cancer: Correlation with Clinical, Imaging and Pathological Features

Seo M, Ryu JK, Jahng GH, Sohn YM, Rhee SJ, Oh JH, Won KY

OBJECTIVE: The purpose of this study was to estimate the T2* relaxation time in breast cancer, and to evaluate the association between the T2* value with clinical-imaging-pathological features of breast...
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Physical Modeling of Chemical Exchange Saturation Transfer Imaging

Jahng GH, Oh JH

Chemical Exchange Saturation Transfer (CEST) imaging is a method to detect solutes based on the chemical exchange of mobile protons with water. The solute protons exchange with three different patterns,...
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Change in Functional Connectivity in Tinnitus and its Relation with Tinnitus Laterality

Song EJ, Ryu CW, Jahng GH, Park MS, Byun JY, Park S, Kim EJ, Choi WS

PURPOSE: To identify potential differences in resting-state networks according to laterality of tinnitus using resting-state functional MRI (fMRI). MATERIALS AND METHODS: A total of 83 age-matched subjects consisting of 19 patients...
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Amide Proton Transfer Imaging in Clinics: Basic Concepts and Current and Future Use in Brain Tumors and Stroke

Park JE, Jahng GH, Jeong HK

Amide proton transfer (APT) imaging is gaining attention as a relatively new in vivo molecular imaging technique that has higher sensitivity and spatial resolution than magnetic resonance spectroscopy imaging. APT...
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Effects of MR Parameter Changes on the Quantification of Diffusion Anisotropy and Apparent Diffusion Coefficient in Diffusion Tensor Imaging: Evaluation Using a Diffusional Anisotropic Phantom

Kim SJ, Choi CG, Kim JK, Yun SC, Jahng GH, Jeong HK, Kim EJ

OBJECTIVE: To validate the usefulness of a diffusional anisotropic capillary array phantom and to investigate the effects of diffusion tensor imaging (DTI) parameter changes on diffusion fractional anisotropy (FA) and...
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Value of Perfusion Weighted Magnetic Resonance Imaging in the Diagnosis of Supratentorial Anaplastic Astrocytoma

Lee KM, Kim EJ, Jahng GH, Park BJ

We report perfusion weighted imaging (PWI) findings of nonenhanced anaplastic astrocytoma in a 30-year-old woman. Brain magnetic resonance imaging showed a nonenhanced brain tumor with mild peritumoral edema on the...
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Correlation of the Speed of Enhancement of Hepatic Hemangiomas with Intravoxel Incoherent Motion MR Imaging

Yang DM, Jahng GH, Kim HC, Kim SW, Kim HG

PURPOSE: To evaluate the relationship between the speed of enhancement of hepatic hemangiomas on gadolinium-enhanced MRI and ADC values by using various parameters, including the D, f, D* and ADC(fit)...
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Investigation of Correlations of Double Inversion Recovery and MR Spectroscopy on Breast MR Imaging

Ryu JK, Rhee SJ, Jahng GH

PURPOSE: To evaluate the correlation of lesion-to-normal ratio (LNR) of signal intensity from double inversion recovery MR imaging and total choline-containing compound (tCho) resonance from single voxel MR spectroscopy in...
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Estimation of T2* Relaxation Times for the Glandular Tissue and Fat of Breast at 3T MRI System

Ryu JK, Oh JH, Kim HG, Rhee SJ, Seo M, Jahng GH

PURPOSE: T2* relaxation time which includes susceptibility information represents unique feature of tissue. The objective of this study was to investigate T2* relaxation times of the normal glandular tissue and...
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High-Resolution MRI of Intracranial Atherosclerotic Disease

Ryu CW, Kwak HS, Jahng GH, Lee HN

Intracranial atherosclerotic disease (ICAD) causes up to 10% of all ischemic strokes, and the rate of recurrent vascular ischemic events is very high. Important predictors of vulnerability in atherosclerotic plaques...
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Perfusion Magnetic Resonance Imaging: A Comprehensive Update on Principles and Techniques

Jahng GH, Li KL, Ostergaard L, Calamante

Perfusion is a fundamental biological function that refers to the delivery of oxygen and nutrients to tissue by means of blood flow. Perfusion MRI is sensitive to microvasculature and has...
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