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Efficacy of Gene Modification in Placenta-Derived Mesenchymal Stem Cells Based on Nonviral Electroporation

Kim JY, Choi JH, Kim SH, Park H, Lee D, Kim GJ

Mesenchymal stem cell (MSC)-based therapy using gene delivery systems has been suggested for degenerative diseases. Although MSC-based clinical applications are effective and safe, the mode of action remains unclear. Researchers...
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Guidelines for Laboratory Diagnosis of Coronavirus Disease 2019 (COVID-19) in Korea

Hong KH, Lee SW, Kim TS, Huh HJ, Lee J, Kim SY, Park JS, Kim GJ, Sung H, Roh KH, Kim JS, Kim HS, Lee ST, Seong MW, Ryoo N, Lee H, Kwon KC, Yoo CK

The outbreak of coronavirus disease 2019 (COVID-19), which began in December 2019, is still ongoing in Korea, with >9,000 confirmed cases as of March 25, 2020. COVID-19 is a severe...
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Psychiatric Distress as a Common Risk Factor for Tinnitus and Joint Pain: A National Population-Based Survey

Park E, Kim H, Choi IH, Han HM, Han K, Jung HH, Im GJ

Objectives. This study aimed to investigate the relationship between tinnitus and joint pain from representative samples of Koreans. Methods. The demographics and the responses to a questionnaire about tinnitus and joint...
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Neuro-Behçet’s Disease Presenting as Isolated Vestibular Syndrome

Park E, Lee SU, Kim HJ, Choi JY, Im GJ, Yu S, Kim JS

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Efficacy of fetal cardiac axis evaluation in the first trimester as a screening tool for congenital heart defect or aneuploidy

Jung YJ, Lee BR, Kim GJ

Objective To prove the efficacy of determining the abnormal fetal cardiac axis for screening congenital heart defects (CHDs) and predicting fetal aneuploidy at 11.0 to 13.6 weeks of pregnancy. Methods This retrospective study was...
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Effective strategy in the treatment of aortobronchial fistula with recurrent hemoptysis

Son SA, Lee DH, Kim GJ

Aortobronchial fistula (ABF) involves the formation of an abnormal connection between the thoracic aorta and the central airways or the pulmonary parenchyma and is associated with an increased risk of...
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Identification of microRNAs and their target genes in the placenta as biomarkers of inflammation

Jang HY, Lim SM, Lee HJ, Hong JS, Kim GJ

Objective: Recently, microRNA (miRNA) has been identified both as a powerful regulator involved in various biological processes through the regulation of numerous genes and as an effective biomarker for the...
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Non-glaucomatous Retinal Nerve Fiber Layer Defect Associated with Paravascular Inner Retinal Defect

Kim GJ, Son DH, Kim JS, Shin MC

PURPOSE: To report a case of non-glaucomatous retinal nerve fiber layer (RNFL) defect associated with paravascular inner retinal defect (PIRD) in a patient with idiopathic epiretinal membrane (ERM). CASE SUMMARY: A...
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Manual Preparation of Donor Lenticule Using Artificial Anterior Chamber for Descemet's Membrane Stripping Endothelial Keratoplasty

Kim GJ, Shin MC, Hwang HS

PURPOSE: To report a patient with a pseudophakic bullous keratopathy (PBK) who underwent Descemet's membrane stripping endothelial keratoplasty (DSEK) with manual preparation of the donor corneal graft. CASE SUMMARY: A 61-year-old...
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Upregulation of C-Reactive Protein by Placenta-Derived Mesenchymal Stem Cells Promotes Angiogenesis in A Rat Model with Cirrhotic Liver

Jun JH, Jung J, Kim JY, Hwang SG, Bae SH, Kim GJ

Background and Objectives: Liver cirrhosis is accompanied by abnormal vascular shunts. The Wnt pathway is essential for endothelial cell survival and proliferation. C-reactive protein (CRP), which is produced by hepatocyte,...
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Impact of the Preoperative Neutrophil to Lymphocyte Ratio on Patients with Head and Neck Cancer

Kim GJ, Kang JM, Seo JH, Hwang SH, Youn HY, Jin HJ, Kang HR, Lee HH, Joo YH

Background and Objectives To investigate the prognostic value of the neutrophil to lymphocyte ratio (NLR) in patients with head and neck squamous cell cancer (HNSCC). Subjects and Method Clinical data from...
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Long-term Clinical Outcomes and Risk of Peritoneal Seeding after Endoscopic Submucosal Dissection for Early Gastric Cancer: A Focus on Perforation during the Procedure

Huh CW, Kim GJ, Kim BW, Seo M, Kim JS

BACKGROUND/AIMS: The risk of peritoneal seeding following perforation after endoscopic resection in patients with early gastric cancer is unclear. The purpose of this study was to investigate long-term clinical outcomes...
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Outcomes of open heart surgery in patients with end-stage renal disease

Park JH, Lim JH, Lee KH, Jung HY, Choi JY, Cho JH, Kim CD, Kim YL, Jung H, Kim GJ, Park SH

BACKGROUND: Cardiovascular diseases of chronic dialysis patients are often undertreated because of their higher surgical risk. This study aimed to assess mortality and morbidity after open heart surgery in chronic...
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The Study of Standardization for a Korean Dizziness Handicap Inventory for Patient Caregivers

Kim TH, Cha HE, Lee JG, Im GJ, Song JJ, Kim SH, Moon IJ, Kim YH, Byun JY, Chae SW

BACKGROUND AND OBJECTIVES: Several questionnaires had been developed to assess the handicap due to dizziness. The questionnaires for adults were used and these had been translated into Korean with validity...
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Factors associated with Oncology Nurses' Adherence to Chemotherapy-Induced Neutropenia Guidelines based on Pender's Health Promotion Model

Kim GJ, Choi JY

PURPOSE: This study was conducted to identify factors associated with oncology nurses' adherence to Chemotherapy-Induced Neutropenia (CIN) guidelines based on Pender's Health Promotion Model (HPM). METHODS: For this cross-sectional descriptive study,...
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Safety and Effectiveness of Endoscopic Ear Surgery: Systematic Review

Jeon MH, Chung S, Kim SH, Oh SH, Im GJ, Kim JR, Choi J, Lee BD

BACKGROUND AND OBJECTIVES: This study aims to evaluate that usefulness of the endoscopic ear surgery (EES) through the systematic review. SUBJECTS AND METHOD: We searched literatures in literature databases (MEDLINE, EMBASE,...
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Analysis of Inner Ear Anomalies in Unilateral Congenital Aural Atresia Combined With Microtia

Park E, Lee G, Jung HH, Im GJ

OBJECTIVES: The aim of this study was to analyze the incidence of inner ear anomalies in patients with unilateral congenital aural atresia (CAA) combined with microtia. METHODS: We retrospectively reviewed 61...
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Fracture of the Bare Spring of a Thoracic Endograft for Type A Aortic Dissection: A Case Report

Son SA, Hahm MH, Kim YE, Kim GJ

Retrograde type A aortic dissection (RTAD) following thoracic endovascular aortic repair is a devastating complication associated with high mortality rates. In particular, a deployed endograft in a bird-beak formation in...
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Alteration of Genomic Imprinting Status of Human Parthenogenetic Induced Pluripotent Stem Cells during Neural Lineage Differentiation

Lee HJ, Choi NY, Lee SW, Lee Y, Ko K, Kim GJ, Hwang HS, Ko K

BACKGROUND AND OBJECTIVES: Genomic imprinting modulates growth and development in mammals and is associated with genetic disorders. Although uniparental embryonic stem cells have been used to study genomic imprinting, there...
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Visuo-Haptic-Based Multimodal Feedback Virtual Reality Solution to Improve Anxiety Symptoms: A Proof-of-Concept Study

Kim YI, Jung SY, Min S, Seol E, Seo S, Hur JW, Jung D, Lee HJ, Lee S, Kim GJ, Cho CY, Choi S, Lee SM, Cho CH

With proper guidance, virtual reality (VR) can provide psychiatric therapeutic strategies within a simulated environment. The visuo-haptic-based multimodal feedback VR solution has been developed to improve anxiety symptoms through immersive...
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