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Conditioning with 10 Gy Total Body Irradiation, Cyclophosphamide, and Fludarabine without ATG Is Associated with Improved Outcome of Cord Blood Transplantation in Children with Acute Leukemia

Cho HW, Ju HY, Hyun JK, Lee Jw, Sung KW, Koo HH, Lim DH, Yoo KH

Background: The optimal conditioning regimen in cord blood transplantation (CBT) needs to be determined. This study aimed to identify the impact of conditioning regimen on the outcome of CBT in...
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Quantification of Thioguanine in DNA Using Liquid Chromatography-Tandem Mass Spectrometry for Routine Thiopurine Drug Monitoring in Patients With Pediatric Acute Lymphoblastic Leukemia

Choi R, Chun MR, Park J, Lee JW, Ju HY, Cho HW, Hyun JK, Koo HH, Yi ES, Lee SY

Background: We developed an assay to measure DNA-incorporated 6-thioguanine (DNATG) and validated its clinical applicability in Korean pediatric patients with acute lymphoblastic leukemia (ALL) in order to improve individualized thiopurine...
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Post-stroke Aphasia as a Prognostic Factor for Cognitive and Functional Changes in Patients With Stroke: Ischemic Versus Hemorrhagic

Seo KC, Ko JY, Kim TU, Lee SJ, Hyun JK, Kim SY

Objective To investigate the comprehensive outcomes in aphasic patients, including their cognitive and functional status after ischemic or hemorrhagic stroke. It also aimed to clarify whether aphasia is a prognostic...
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Clinical Significance of Segmental Chromosomal Aberrations in Patients with Neuroblastoma: First Report in Korean Population

Lim H, Son MH, Hyun JK, Cho HW, Ju HY, Lee JW, Yoo KH, Sung KW, Koo HH

Background This study aimed to investigate the incidence and clinical significance of segmental chromosomal aberrations (SCAs) in Korean patients with neuroblastoma. Methods Patients diagnosed with neuroblastoma from 2012 to 2018 were included for...
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A Case of Hereditary Spherocytosis Initially Manifested as an Aplastic Crisis Caused by Parvovirus B19 Infection

Jin H, Lee JW, Ju HY, Cho HW, Hyun JK, Sung KW, Koo HH, Kim HJ, Yoo KH

Hereditary spherocytosis (HS) is the most common inherited red cell membrane disorder. Its main laboratory finding is anemia with reticulocytosis. However, in the case of an aplastic crisis, there may...
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The Effect of Cryopreservation of Allograft Nerve on the Recovery of Motor Function

Choi SS, Park I, Hyun JK, Jung JU, Kim JP

PURPOSE: Peripheral nerve allograft can be an acceptable alternative, but it has not yet become clinically useful because of immune response to foreign tissue. With significant advances in the research...
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Effect of Delayed Elevation of Thyrotropin on Feeding Intolerance in Very Low Birth Weight Infants

Hyun JK, Choi SY, Jung YJ, Lee JH

PURPOSE: We investigated the effect of delayed elevation of thyrotropin (TSH) (deTSH) on gastrointestinal motility in very low birth weight infants (VLBWI). METHODS: This study retrospectively investigated 228 premature VLBWI aged...
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Repetitive Transcranial Magnetic Stimulation Enhances Recovery in Central Cord Syndrome Patients

Choi H, Seo KC, Kim TU, Lee SJ, Hyun JK

OBJECTIVE: To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on neurological and functional recovery in patients with central cord syndrome (CCS) involving the upper extremities between the treated...
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Botulinum Toxin Injection in the Treatment of Postextubation Dysphagia: A Case Report

Kim BW, Kim HJ, Hyun JK, Kim SY, Kim TU

Prolonged intubation is known to bring on postextubation dysphagia (PED) in some patients. We have noted that there were some studies to investigate specific type and pattern of PED, which...
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Diagnostic distal 16p11.2 deletion in a preterm infant with facial dysmorphism

Hyun JK, Jung YJ

The 16p11.2 microdeletion has been reported in patients with developmental delays and intellectual disability. The distal 220-kb deletion in 16p11.2 is associated with developmental delay, autism spectrum disorder, epilepsy, and...
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Influence of Hip Fracture on Knee Pain During Postoperative Rehabilitation

Kim HJ, Lee SJ, Hyun JK, Kim SY, Kim TU

OBJECTIVE: To investigate whether fracture type, surgical procedure, or fracture grade affect knee pain during postoperative rehabilitation after a hip fracture. METHODS: We conducted a retrospective case-controlled study of 139 patients...
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Effects of Early Cranioplasty on the Restoration of Cognitive and Functional Impairments

Kim BW, Kim TU, Hyun JK

OBJECTIVE: To delineate the effect of early cranioplasty on the recovery of cognitive and functional impairments in patients who received decompressive craniectomy after traumatic brain injury or spontaneous cerebral hemorrhage. METHODS:...
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Effect of Laryngopharyngeal Neuromuscular Electrical Stimulation on Dysphonia Accompanied by Dysphagia in Post-stroke and Traumatic Brain Injury Patients: A Pilot Study

Ko KR, Park HJ, Hyun JK, Seo IH, Kim TU

OBJECTIVE: To investigate the effect of laryngopharyngeal neuromuscular electrical stimulation (NMES) on dysphonia in patients with dysphagia caused by stroke or traumatic brain injury (TBI). METHODS: Eighteen patients participated in this...
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Factors Associated With Upper Extremity Functional Recovery Following Low-Frequency Repetitive Transcranial Magnetic Stimulation in Stroke Patients

Kim SY, Shin SB, Lee SJ, Kim TU, Hyun JK

OBJECTIVE: To investigate the factors related to upper extremity functional improvement following inhibitory repetitive transcranial magnetic stimulation (rTMS) in stroke patients. METHODS: Forty-one stroke patients received low-frequency rTMS over the contralesional...
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Diagnosis of Spasmodic Dysphonia Manifested by Swallowing Difficulty in Videofluoroscopic Swallowing Study

Yeo HG, Lee SJ, Hyun JK, Kim TU

Spasmodic dysphonia is defined as a focal laryngeal disorder characterized by dystonic spasms of the vocal cord during speech. We described a case of a 22-year-old male patient who presented...
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The Prediction of Clinical Outcome Using HbA1c in Acute Ischemic Stroke of the Deep Branch of Middle Cerebral Artery

Shin SB, Kim TU, Hyun JK, Kim JY

OBJECTIVE: To elucidate the association between glycemic control status and clinical outcomes in patients with acute ischemic stroke limited to the deep branch of the middle cerebral artery (MCA). METHODS: We...
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Family History and Functional Outcome in Korean Stroke Patients: A Preliminary Study

Park HJ, Kim TU, Hyun JK, Kim JY

OBJECTIVE: To investigate the association of family history of stroke with functional outcomes in stroke patients in Korea. METHODS: A case-control study was conducted. A total of 170 patients who were...
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Prognosis for Patients With Traumatic Cervical Spinal Cord Injury Combined With Cervical Radiculopathy

Kim SY, Kim TU, Lee SJ, Hyun JK

OBJECTIVE: To delineate cervical radiculopathy that is found in combination with traumatic cervical spinal cord injury (SCI) and to determine whether attendant cervical radiculopathy affects the prognosis and functional outcome...
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Radiologic Assessment of Forward Head Posture and Its Relation to Myofascial Pain Syndrome

Sun A, Yeo HG, Kim TU, Hyun JK, Kim JY

OBJECTIVE: To assess head posture using cervical spine X-rays to find out whether forward head posture is related to myofascial pain syndrome (MPS) in neck and shoulder. METHODS: Eighty-eight participants who...
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The Clinical Effect of Botulinum Toxin in a Patient with Tourette's Syndrome : A Case Report and Review

Hyun JK, Lee JH, Lee CM, Lim MH

  • KMID: 2291632
  • J Korean Acad Child Adolesc Psychiatry.
  • 2013 Jun;24(2):90-95.
Botulinum toxin, a neurotoxin, is known to be an inhibitor of cholinergic neuromuscular transmission. Recently, it was reported that the administration of botulinum toxin is effective for the treatment of...
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