- Prognostic Value of Alpha-Fetoprotein in Patients Who Achieve a Complete Response to Transarterial Chemoembolization for Hepatocellular Carcinoma
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Lee JS, Chon YE, Kim BK, Park JY, Kim DY, Ahn SH, Han KH, Kang W, Choi MS, Gwak GY, Paik YH, Lee JH, Koh KC, Paik SW, Kim HY, Kim TH, Yoo K, Ha Y, Kim MN, Lee JH, Hwang SG, Kim SS, Cho HJ, Cheong JY, Cho SW, Park SH, Heo NY, Hong YM, Yoon KT, Cho M, Park JG, Kang MK, Park SY, Kweon YO, Tak WY, Jang SY, Sinn DH, Kim SU, The Korean TACE Study Group
- KMID: 2509849
- Yonsei Med J.
- 2021 Jan;62(1):12-20.
- doi: 10.3349/ymj.2021.62.1.12
Purpose: Alpha-fetoprotein (AFP) is a prognostic marker for hepatocellular carcinoma (HCC). We investigated the prognostic value of AFP levels in patients who achieved complete response (CR) to transarterial chemoembolization (TACE)... -
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- Upregulation of C-Reactive Protein by Placenta-Derived Mesenchymal Stem Cells Promotes Angiogenesis in A Rat Model with Cirrhotic Liver
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Jun JH, Jung J, Kim JY, Hwang SG, Bae SH, Kim GJ
- KMID: 2508914
- Int J Stem Cells.
- 2020 Nov;13(3):404-413.
- doi: 10.15283/ijsc20052
Background and Objectives: Liver cirrhosis is accompanied by abnormal vascular shunts. The Wnt pathway is essential for endothelial cell survival and proliferation. C-reactive protein (CRP), which is produced by hepatocyte,... -
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- Association between hepatic steatosis and the development of hepatocellular carcinoma in patients with chronic hepatitis B
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Lee YB, Ha Y, Chon YE, Kim MN, Lee JH, Park H, Kim KI, Kim SH, Rim KS, Hwang SG
- KMID: 2447251
- Clin Mol Hepatol.
- 2019 Mar;25(1):52-64.
- doi: 10.3350/cmh.2018.0040
BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is becoming a worldwide epidemic, and is frequently found in patients with chronic hepatitis B (CHB). We investigated the impact of histologically proven hepatic... -
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- An Analysis on Prescribing Patterns of Alzheimer's Dementia Treatment and Choline Alfoscerate using HIRA Claims Data
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Hwang SG, Park H
- KMID: 2446869
- Korean J Clin Pharm.
- 2019 Mar;29(1):1-8.
- doi: 10.24304/kjcp.2019.29.1.1
BACKGROUND: Alzheimer's dementia is the most common dementia. However, recently, choline alfoscerate is prescribed for treating Alzheimer's dementia, although it is not a treatment for this disease. PURPOSE: To analyze the... -
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- Liver Cirrhosis, Not Antiviral Therapy, Predicts Clinical Outcome in Cohorts with Heterogeneous Hepatitis B Viral Status
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Kim MN, Hwang SG, Kim BK, Park JY, Kim DY, Han KH, Kim SU, Ahn SH
- KMID: 2446805
- Gut Liver.
- 2019 Mar;13(2):197-205.
- doi: 10.5009/gnl18204
BACKGROUND/AIMS: Antiviral therapy (AVT) reduces the risk of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B (CHB). This multicenter retrospective study investigated the effects of AVT and hepatitis... -
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- Sarcopenia Predicts Prognosis in Patients with Newly Diagnosed Hepatocellular Carcinoma, Independent of Tumor Stage and Liver Function
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Ha Y, Kim D, Han S, Chon YE, Lee YB, Kim MN, Lee JH, Park H, Rim KS, Hwang SG
- KMID: 2417873
- Cancer Res Treat.
- 2018 Jul;50(3):843-851.
- doi: 10.4143/crt.2017.232
PURPOSE: The purpose of this study was to demonstrate the prognostic significance of changes in body composition in patients with newly diagnosed hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Patients (n=178) newly... -
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- A Case of Management for Advanced Hepatocellular Carcinoma with Extrahepatic Metastasis by Autologous Natural Killer Cells Combined with Immune Checkpoint Inhibitor
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Woo A, Kim EJ, Shin SY, Jeon HJ, Park H, Chon YE, Lee YB, Hwang SG, Rim KS, Lee JH
- KMID: 2409651
- J Liver Cancer.
- 2018 Mar;18(1):67-74.
- doi: 10.17998/jlc.18.1.67
Hepatocellular carcinoma (HCC) has extremely poor prognosis. Immunotherapy has emerged as a new treatment for a number of cancers. Adoptive immunotherapy is one of the important cancer immunotherapy, which relies... -
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- What is the Clinical Significance of Initial Lactate Measurement Compared to Carboxyhemoglobin Measurement in Carbon Monoxide Poisoning?
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Hwang SG, Jin SC, Choi WI, Jeon JC, Kim TK
- KMID: 2394397
- J Korean Soc Emerg Med.
- 2017 Oct;28(5):484-492.
- doi: 10.0000/jksem.2017.28.5.484
PURPOSE: This study was performed to compare clinical significance between lactate and carboxyhemoglobin (COHb) in a patient with carbon monoxide (CO) poisoning. METHODS: We conducted a 13-year retrospective study on CO... -
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- Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study
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Cho EY, Yim HJ, Jung YK, Suh SJ, Seo YS, Kim JH, Kim HS, Lee SH, Ahn SH, Lee JI, Jeong SH, Kim JW, Lee JW, Kim IH, Kim HS, Park SJ, Lee JM, Hwang SG
- KMID: 2412164
- Gut Liver.
- 2017 Jan;11(1):129-135.
- doi: 10.5009/gnl15597
BACKGROUND/AIMS: Data are lacking regarding the management of chronic hepatitis B (CHB) with resistance to clevudine (CLV). This study evaluated the efficacy of different rescue therapies for CLV-resistant CHB. METHODS: Patients... -
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- Hepatic Infarction Caused by Portal Vein Thrombophlebitis Misdiagnosed as Infiltrative Hepatic Malignancy with Neoplastic Thrombus
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Shim M, Yang TY, Cho NG, Woo A, Kim E, Park K, Lee JH, Lee YB, Hwang SG, Rim KS, Park H
- KMID: 2358719
- Korean J Gastroenterol.
- 2016 Sep;68(3):156-160.
- doi: 10.4166/kjg.2016.68.3.156
Portal vein thrombosis (PVT) is a form of venous thrombosis that usually presents in chronic form without any sequalae in patients with hepatocellular carcinoma (HCC) or liver cirrhosis. Accurate differential... -
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- Living Donor Liver Transplantation in a Hepatitis B Patient with Acute on Chronic Liver Failure Accompanying Hepatocellular Carcinoma
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Hong HJ, Lee JH, Lee YB, Park H, Hwang SG, Rim KS
- KMID: 2344895
- Ewha Med J.
- 2016 Jul;39(3):76-80.
- doi: 10.12771/emj.2016.39.3.76
Acute clinical deterioration in patients with chronic liver disease is called acute on chronic liver failure (ACLF). Principles of management of ACLF consist of early identifying etiology of liver disease,... -
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- A Case of Severe Peripheral Polyneuropathy Occurring after Entecavir Treatment in a Hepatitis B Patient
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Song JH, Kim SY, Shin JK, Hong SD, Rim KS, Park HN, Lee JH, Lee YB, Oh SH, Hwang SG
- KMID: 2373428
- Korean J Gastroenterol.
- 2016 Apr;67(4):216-219.
- doi: 10.4166/kjg.2016.67.4.216
Entecavir (Baraclude®) is an oral antiviral drug used for the treatment of HBV. Entecavir is a reverse transcriptase inhibitor which prevents the HBV from multiplying. Most common adverse reactions caused... -
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- Fluoroscopy-induced Subacute Radiation Dermatitis in Patient with Hepatocellular Carcinoma
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Kim BH, Kim HK, Shin JK, Hong HJ, Lee JH, Park H, Hwang SG, Rim KS
- KMID: 2383551
- Korean J Gastroenterol.
- 2016 Feb;67(2):112-115.
- doi: 10.4166/kjg.2016.67.2.112
Radiation dermatitis can develop after fluoroscopy-guided interventional procedures. Cases of fluoroscopy-induced radiation dermatitis have been reported since 1996, mostly documented in the fields of radiology, cardiology and dermatology. Since diagnosis... -
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- A Case of Concurrent Chemoradiation Therapy for Locally Advanced Hepatocellular Carcinoma with Portal Vein Thrombosis
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Yang TY, Shin SP, Lee JH, Lee YB, Park H, Hwang SG, Rim KS
- KMID: 2154075
- J Liver Cancer.
- 2015 Mar;15(1):52-56.
- doi: 10.0000/jlc.2015.15.1.52
Patients with advanced hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT) have an extremely poor prognosis. Although the Barcelona Clinic Liver Cancer guideline recommends sorafenib in advanced HCC with PVT,... -
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- Occult Hepatitis B Virus Infection: Transmission and Reactivation
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Song SH, Hwang SG
- KMID: 1707196
- Korean J Gastroenterol.
- 2013 Sep;62(3):148-153.
- doi: 10.4166/kjg.2013.62.3.148
Occult HBV infection (OBI) is defined as presence of HBV DNA in the liver tissue in patients with serologically undetectable HBsAg. There are differences in virologic and serological profiles of... -
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- Options for the management of antiviral resistance during hepatitis B therapy: reflections on battles over a decade
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Yim HJ, Hwang SG
- KMID: 1705199
- Clin Mol Hepatol.
- 2013 Sep;19(3):195-209.
- doi: 10.3350/cmh.2013.19.3.195
Although much advancement has been achieved in the treatment of chronic hepatitis B, antiviral resistance is still a challenging issue. Previous generation antiviral agents have already developed resistance in a... -
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- Effects of Metabolic Syndrome on Fibrosis in Chronic Viral Hepatitis
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Yoon H, Lee JG, Yoo JH, Son MS, Kim DY, Hwang SG, Rim KS
- KMID: 1806647
- Gut Liver.
- 2013 Jul;7(4):469-474.
BACKGROUND/AIMS: Metabolic syndrome, comprising diabetes, hypertension, central obesity, and dyslipidemia, is increasingly prevalent worldwide. We aimed to study the relationship between metabolic syndrome and the risk of liver fibrosis in... -
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- Hepatitis B Core Antigen Expression in Hepatocytes Reflects Viral Response to Entecavir in Chronic Hepatitis B Patients
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Lee JG, Hwang SG, Yoon H, Son MS, Kim DY, Yoo JH, Kim KI, Rim KS
- KMID: 1806646
- Gut Liver.
- 2013 Jul;7(4):462-468.
BACKGROUND/AIMS: Hepatitis B core antigen is known to be a major target for virus-specific T cells and also reflects the progression of liver dissease and viral replication. Hepatitis B core... -
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- Efficacy and safety of entecavir plus carnitine complex (GODEX(R)) compared to entecavir monotherapy in patient with ALT elevated chronic hepatitis B: randomized, multicenter open-label trials. The GOAL study
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Jun DW, Kim BI, Cho YK, Kim HJ, Kwon YO, Park SY, Han SY, Baek YH, Jung YJ, Kim HY, Kim W, Heo J, Woo HY, Hwang SG, Rim KS, Choi JY, Bae SH, Lee YS, Lim YS, Cheong JY, Cho SW, Lee BS, Kim SH, Sohn JH, Kim TY, Paik YH, Kim JK, Lee KS
- KMID: 1776804
- Clin Mol Hepatol.
- 2013 Jun;19(2):165-172.
- doi: 10.3350/cmh.2013.19.2.165
BACKGROUND/AIMS: Carnitine and vitamin complex (Godex(R)) is widely used in patients with chronic liver disease who show elevated liver enzyme in South Korea. The purpose of this study is to... -
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- Prevalence of Occult Hepatitis B Virus Infection in Hemodialysis Patients
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Yoo JH, Hwang SG, Yang DH, Son MS, Kwon CI, Ko KH, Hong SP, Park PW, Rim KS
- KMID: 1775760
- Korean J Gastroenterol.
- 2013 Apr;61(4):209-214.
- doi: 10.4166/kjg.2013.61.4.209
BACKGROUND/AIMS: The prevalence of occult HBV infection depends on the prevalence of HBV infection in the general population. Hemodialysis patients are at increased risk for HBV infection. The aim of... -
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