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Analysis  of  the  Satisfaction  with  Computer  Based  Test  Program  and  Test  Environment  in  Medical  School

Kim SG, Lee Ah, Hwang Is

This study aimed to identify needed improvements to current evaluation methods in medical school computer-based test (CBT) programs and test environments. To that end, an analysis of the importance and...
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Detection of Immunoglobulin Heavy Chain Gene Clonality by Next-Generation Sequencing for Minimal Residual Disease Monitoring in B-Lymphoblastic Leukemia

Shin S, Hwang IS, Kim J, Lee KA, Lee ST, Choi JR

Minimal residual disease (MRD) following B-lymphoblastic leukemia (B-ALL) treatment has gained prognostic importance. Clonal immunoglobulin heavy chain (IGH) gene rearrangement is a useful follow-up marker in B-ALL owing to its...
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Next-generation sequencing of BRCA1/2 in breast cancer patients: potential effects on clinical decision-making using rapid, high-accuracy genetic results

Park HS, Park SJ, Kim JY, Kim S, Ryu J, Sohn J, Park S, Kim GM, Hwang IS, Choi JR, Kim SI

PURPOSE: We evaluated the clinical role of rapid next-generation sequencing (NGS) for identifying BRCA1/2 mutations compared to traditional Sanger sequencing. METHODS: Twenty-four paired samples from 12 patients were analyzed in this...
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Effects of Neutralization by Soluble ABH Antigens Produced by Transplanted Kidneys From ABO-Incompatible Secretor Donors

Kim J, Kim S, Hwang IS, Choi JR, Lee JG, Kim YS, Kim MS, Kim HO

BACKGROUND: Grafts survive despite blood group antigens on the transplant being continuously exposed to antibodies in the blood of recipients in ABO-incompatible kidney transplantation (ABOi KT), owing to the mechanism...
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Malignant Transformation of Pulmonary Benign Metastasizing Leiomyoma

Song KS, Keum DY, Hwang IS

Pulmonary benign metastasizing leiomyoma (PBML) is defined as metastasis of a leiomyoma to lung tissue. It was first reported in 1937. P BML is known as a benign disease, but...
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Molecular cloning and characterization of porcine ribosomal protein L21

Sun WS, Chun JL, Kim DH, Ahn JS, Kim MK, Hwang IS, Kwon DJ, Hwang S, Lee JW

Ribosomal protein L21 (RPL21) is a structural component of the 60S subunit of the eukaryotic ribosome. This protein has an important role in protein synthesis and the occurrence of hereditary...
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Mature Ovarian Teratoma with Large Floating Fat Globules

Son HM, Kim SH, Hwang IS

Mature ovarian teratoma (dermoid cyst), a germ cell neoplasm, is one of the most common ovarian tumors. It is composed of derivatives of three germ cell layers. A mature ovarian...
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Bone Marrow Chimerism Detection Using Next Generation Sequencing Based on Single Nucleotide Polymorphisms Following Liver Transplantation: Comparison With Short Tandem Repeat-PCR

Kim J, Hwang IS, Kim HS, Joo DJ, Hong KR, Choi JR

No abstract available.
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Knockdown of Bcl-xL Enhances Growth-Inhibiting and Apoptosis-Inducing Effects of Resveratrol and Clofarabine in Malignant Mesothelioma H-2452 Cells

Lee YJ, Hwang IS, Lee YJ, Lee CH, Kim SH, Nam HS, Choi YJ, Lee SH

Mcl-1 and Bcl-xL, key anti-apoptotic proteins of the Bcl-2 family, have attracted attention as important molecules in the cell survival and drug resistance. In this study, we investigated whether inhibition...
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Mitochondrial and DNA damage in bovine somatic cell nuclear transfer embryos

Hwang IS, Bae HK, Cheong HT

The generation of reactive oxygen species (ROS) and subsequent mitochondrial and DNA damage in bovine somatic cell nuclear transfer (SCNT) embryos were examined. Bovine enucleated oocytes were electrofused with donor...
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Usefulness of the Ice-Cream Cone Pattern in Computed Tomography for Prediction of Angiomyolipoma in Patients With a Small Renal Mass

Kim KH, Yun BH, Jung SI, Hwang IS, Hwang EC, Kang TW, Kwon DD, Park K, Kim JW

PURPOSE: A morphologic contour method for assessing an exophytic renal mass as benign versus malignant on the basis of the shape of the interface with the renal parenchyma was recently...
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Alcohol Problems and Related Service Needs in Urban Korean Community

Yang J, Whang SY, Hwang IS, Kim SM, Bae GH, Lee HJ, Ko YH

  • KMID: 1432863
  • Korean J Psychosom Med.
  • 2013 Jun;21(1):62-71.
OBJECTIVES: The purpose of this study is to investigate the characteristics of drinking patterns and the prevalence of hazardous drinking and alcohol use disorder with the assessment of alcohol policy...
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Predicting Factors for Stent Failure-Free Survival in Patients With a Malignant Ureteral Obstruction Managed With Ureteral Stents

Yu SH, Ryu JG, Jeong SH, Hwang EC, Jang WS, Hwang IS, Yu HS, Kim SO, Jung SI, Kang TW, Kwon DD, Park K, Hwang JE, Kim GS

PURPOSE: To determine predictive factors for stent failure-free survival in patients treated with a retrograde ureteral stent for a malignant ureteral obstruction. MATERIALS AND METHODS: We retrospectively reviewed 71 patients who...
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Gross Hematuria Associated with Genitourinary Tuberculosis

Bae EH, Heo S, Kim YH, Hwang IS, Choi JS, Kim CS, Ma SK, Kim SW

A 27-year-old man presented to the emergency department with sudden onset of massive gross hematuria and urinary retention. Contrast-enhanced computed tomography imaging showed uneven, dilated calices and a narrowing of...
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A Comparative Study of the Diagnostic Performance of the GENEDIA Avellino Corneal Dystrophy Mutation Detection Kit and Screening Master Mix and a Direct Sequencing Method to Detect Mutations in the TGFB1 Gene

Yu N, Hwang IS, Hong KR, Ahn MS, Park SJ, Choi JR

  • KMID: 2200493
  • J Lab Med Qual Assur.
  • 2013 Dec;35(2):115-121.
BACKGROUND: Mutations in the gene encoding transforming growth factor-beta induced (TGFBI) are associated with corneal dystrophies. We evaluated the diagnostic performance of the GENEDIA Avellino corneal dystrophy (ACD) mutation detection...
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Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats

Kim JE, Hwang IS, Choi SI, Lee HR, Lee YJ, Goo JS, Lee HS, Son HJ, Jang MJ, Lee SH, Kang BC, Hwang DY

Liriope platyphylla is a medical herb that has long been used in Korea and China to treat cough, sputum, neurodegenerative disorders, obesity, and diabetes. The aims of this study were...
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Effects of Red Liriope platyphylla on NGF secretion ability, NGF receptor signaling pathway and gamma-secretase components in NSE/hAPPsw transgenic mice expressing Alzheimer's Disease

Choi SI, Goo JS, Kim JE, Hwang IS, Lee HR, Lee YJ, Son HJ, Lee HS, Lee JS, Hwang DY

Liriope platyphylla (LP) has long been regarded as a curative herb for the treatment of diabetes, asthma, and neurodegenerative disorders. To examine the therapeutic effects of Red LP (RLP) manufactured...
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Sleep Status and Quality of Life in Patients with Frozen Shoulder

Cho CH, Jung SW, Son ES, Hwang IS

PURPOSE: The aims of this study were to assess sleep status and quality of life (QOL) in patients with frozen shoulder and to evaluate correlations between pain, disability, sleep disturbance...
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Monitoring of antibiotic resistance in bacteria isolated from laboratory animals

Goo JS, Jang MK, Shim SB, Jee SW, Lee SH, Bae CJ, Park S, Kim KJ, Kim JE, Hwang IS, Lee HR, Choi SI, Lee YJ, Lim CJ, Hwang DY

The drug resistance of microorganisms isolated from laboratory animals never treated with antibiotics is being reported consistently, while the number of laboratory animals used in medicine, pharmacy, veterinary medicine, agriculture,...
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Altered expression of gamma-secretase components in animal model of major depressive disorder induced by reserpine administration

Lee HR, Hwang IS, Kim JE, Choi SI, Lee YJ, Goo JS, Lee EP, Choi HW, Kim HS, Lee JH, Jung YJ, Hwang DY

Altered expression of neurotrophic factors as well as neuroinflammation is commonly associated with Major depressive disorder (MDD) and Alzheimer's disease (AD). To investigate whether or not reserpine-induced MDD affects the...
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