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Human Cytomegalovirus (HCMV)-infected Astrocytoma Cells Impair the Function of HCMV-specific Cytotoxic T Cells

Kim J, Lee WW, Hwang ES

Background: Human cytomegalovirus (HCMV) infection in glioblastoma multiforme (GBM) is associated with a poor prognosis and may affect the pathogenesis of GBM. In this study, we investigated the role of...
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World Outbreak Trend of Infectious Diseases with Surveillance

Choi SY, Kim JH, Kim J, Hwang ES

The diverse infectious diseases can occur everywhere in the world, but high-risk infectious diseases should be monitored immediately after the occurrence, and be controlled not to spread to the public....
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Rapid Whole-genome Sequencing of Zika Viruses using Direct RNA Sequencing

Kim JH, Kim J, Koo BS, Oh H, Hong JJ, Hwang ES

Zika virus (ZIKV) is one of the pathogens which is transmitted world widely, but there are no effective drugs and vaccines. Whole genome sequencing (WGS) of viruses could be applied...
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Predictors of Severe or Moderate Coronary Artery Disease in Asymptomatic Individuals with Extremely Low Coronary Calcium Scores

Park HB, Jeong H, Lee JH, Suh Y, Hwang ES, Cho YH, Cho DK

PURPOSE: To evaluate predictors of severe or moderate coronary artery disease (CAD) in individuals with zero or very low (
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A Study on Knowledge, Importance and Performance in Nursing Records of University Hospital Nurses

Hwang ES, Lee SJ, Kim SJ, Heo IH

PURPOSE: The purpose of this study was to assess hospital nurses' knowledge, importance and performance in keeping nursing records. METHODS: The research design was a descriptive study. The sample for this...
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Effects of Multidisciplinary Lifestyle Modification Program on Health-promoting Behavior, Psychological Distress, Body Composition and Reproductive Symptoms among Overweight and Obese Middle-aged Women

Nho JH, Hwang ES

PURPOSE: This study aimed to examine the effect of multidisciplinary lifestyle modification program in overweight or obese middle-aged women. METHODS: This study was conducted from January 2 to June 5, 2018...
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Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats

Lee S, Kim HB, Hwang ES, Kim ES, Kim SS, Jeon TD, Song MC, Lee JS, Chung MC, Maeng S, Park JH

Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its commonness, the pathophysiology of depression remains...
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Enhancement of Replication and Differentiation Potential of Human Bone Marrow Stem Cells by Nicotinamide Treatment

Ok JS, Song SB, Hwang ES

BACKGROUND AND OBJECTIVES: Therapies using mesenchymal stem cells (MSCs) generally require substantial expansion of cell populations. However, the replicative life span of MSCs is limited and their multipotency declines over...
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An Urgent Need for Global Preparedness against the Reemergence of “Forgotten” Infectious Diseases in Korea

Kim JH, Bae W, Kim J, Hwang ES

No abstract available.
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Changes of Epidemiological Characteristics of Japanese Encephalitis Viral Infection and Birds as a Potential Viral Transmitter in Korea

Bae W, Kim JH, Kim J, Lee J, Hwang ES

Japanese encephalitis (JE) cases have been increasingly reported recently especially in Seoul and its vicinity. Pigs are known as amplifying host of JE virus (JEV), but do not play an...
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Interleukin-32 Gamma as a New Face in Inflammatory Bone Diseases

Lee EJ, Choi B, Hwang ES, Chang EJ

Interleukin-32 (IL-32), a recently identified pro-inflammatory cytokine, is involved in the pathogenesis and progression of infections, cancer, chronic inflammation, and autoimmune disease. IL-32γ is the most active isoform in cell...
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Cellular NAD⁺ Level: A Key Determinant of Mitochondrial Quality and Health

Hwang ES, Hwang SY

The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen species generation; therefore, it plays critical roles in energy homeostasis and cellular health. Mitochondrial quality...
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The Effect of a Scenario based Hand Hygiene Education Program on Hand Hygiene Knowledge, Hand Hygiene Perception, Hand Hygiene Compliance and Hand Hygiene Method in Nursing Students

Hwang ES, Park JH

PURPOSE: This study was conducted to test the effect of a scenario based hand hygiene education program on hand hygiene knowledge, hand hygiene perception, hand hygiene compliance and hand hygiene...
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Epidemiological Characteristics and Risk Factors of Dengue Infection in Korean Travelers

Je S, Bae W, Kim J, Seok SH, Hwang ES

Dengue viral infection has rapidly spread around the world in recent decades. In Korea, autochthonous cases of dengue fever have not been confirmed yet. However, imported dengue cases have been...
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Distribution of Human Rotavirus Genotypes in a Tertiary Hospital, Seoul, Korea During 2009-2013

Han TH, Park SH, Chung JY, Hwang ES

PURPOSE: Group A rotavirus (RV) is most common etiologic agent of acute gastroenteritis (AGE) in children worldwide. Recently, vaccination has been introduced in several countries to reduce the disease burden...
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Anti-proliferative Activity of T-bet

Oh YJ, Shin JH, Won HY, Hwang ES

T-bet is a critical transcription factor that regulates differentiation of Th1 cells from CD4+ precursor cells. Since T-bet directly binds to the promoter of the IFN-gamma gene and activates its...
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Nucleotide Binding Oligomerization Domain 1 Is an Essential Signal Transducer in Human Epithelial Cells Infected with Helicobacter pylori That Induces the Transepithelial Migration of Neutrophils

Kim BJ, Kim JY, Hwang ES, Kim JG

BACKGROUND/AIMS: The cytosolic host protein nucleotide binding oligomerization domain 1 (Nod1) has emerged as a key pathogen recognition molecule for innate immune responses in epithelial cells. The purpose of the...
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The Preparedness for Re-emerged and Emerging Infectious Diseases: A Lesson Through Outbreak of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in South Korea

Je S, Bae W, Kim J, Seok SH, Hwang ES

The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory disease and systemic dysfunction that may eventually lead to the death of the patients. After MERS-CoV was first diagnosed...
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Cardiovascular Events of Electrical Cardioversion Under Optimal Anticoagulation in Atrial Fibrillation: The Multicenter Analysis

Shin DG, Cho I, Hartaigh B, Mun HS, Lee HY, Hwang ES, Park JK, Uhm JS, Pak HN, Lee MH, Joung B

PURPOSE: Electric cardioversion has been successfully used in terminating symptomatic atrial fibrillation (AF). Nevertheless, largescale study about the acute cardiovascular events following electrical cardioversion of AF is lacking. This study...
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Preparedness for Prevention of Ebola Virus Disease

Hwang ES

No abstract available.
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