- Far-infrared rays enhance mitochondrial biogenesis and GLUT3 expression under low glucose conditions in rat skeletal muscle cells
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Seo Y, Kim YW, Lee D, Kim D, Kim K, Kim T, Baek C, Lee Y, Lee J, Lee H, Jang G, Jeong W, Choi J, Hwang D, Suh JS, Kim SW, Kim HK, Han J, Bang H, Kim JH, Zhou T, Ko JH
- KMID: 2512960
- Korean J Physiol Pharmacol.
- 2021 Mar;25(2):167-175.
- doi: 10.4196/kjpp.2021.25.2.167
Far-infrared rays (FIR) are known to have various effects on atoms and molecular structures within cells owing to their radiation and vibration frequencies. The present study examined the effects of... -
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- Inflammatory responses of C57BL/6NKorl mice to dextran sulfate sodium-induced colitis: comparison between three C57BL/6 N sub-strains
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Kim SH, Kwon D, Son SW, Jeong TB, Lee S, Kwak JH, Cho JY, Hwang DY, Seo MS, Kim KS, Jung YS
- KMID: 2514398
- Lab Anim Res.
- 2021 Mar;37(1):67-73.
- doi: 10.1186/s42826-021-00084-2
Background: Inflammatory bowel disease (IBD), including both Crohn’s disease and ulcerative colitis, are chronic human diseases that are challenging to cure and are often unable to be resolved. The inbred... -
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- Physiologic Assessment after Coronary Stent Implantation
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Hwang D, Yang S, Zhang J, Koo BK
- KMID: 2513517
- Korean Circ J.
- 2021 Mar;51(3):189-201.
- doi: 10.4070/kcj.2020.0548
The presence of myocardial ischemia is a prerequisite for the benefit of coronary revascularization. In the cardiac catheterization laboratory, fractional flow reserve and non-hyperemic pressure ratios are used to define... -
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- Comparison of response to LPS-induced sepsis in three DBA/2 stocks derived from different sources
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Park JW, Lee SJ, Kim JE, Kang MJ, Bae SJ, Choi YJ, Gong JE, Kim KS, Jung YS, Cho JY, Choi YS, Hwang DY, Song HK
- KMID: 2514374
- Lab Anim Res.
- 2021 Mar;37(1):44-52.
- doi: 10.1186/s42826-020-00079-5
Sepsis, one of the most fatal diseases in the world, is known to culminate in multiple organ failure due to an uncontrolled inflammatory response. Hence, the use of animal models... -
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- Association of Quantitative Flow Ratio with Lesion Severity and Its Ability to Discriminate Myocardial Ischemia
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Dai N, Hwang D, Lee JM, Zhang J, Tong Y, Jeon KH, Paeng JC, Cheon GJ, Koo BK, Ge J
- KMID: 2512450
- Korean Circ J.
- 2021 Feb;51(2):126-139.
- doi: 10.4070/kcj.2020.0375
Background and Objectives: Quantitative flow ratio (QFR) is an angiography-based technique for functional assessment of coronary artery stenosis. This study investigated the response of QFR to different degree of stenosis... -
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- Long-Term Result of Tibioperoneal Trunk Bypass with an Autogenous Graft Using the Varicose Great Saphenous Vein for Acute Limb Ischemia
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Kim HK, Hwang D, Huh S
- KMID: 2507177
- Vasc Spec Int.
- 2020 Sep;36(3):170-173.
- doi: 10.5758/vsi.200033
For the management of acute limb ischemia (ALI) and multilevel arterial occlusive disease, tibial bypass using the saphenous vein has been considered a mainstay due to the long-term durability in... -
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- Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment
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Kang MJ, Gong JE, Kim JE, Choi HJ, Bae SJ, Seo MS, Kim KS, Jung YS, Cho JY, Lim Y, Hwang DY
- KMID: 2507238
- Lab Anim Res.
- 2020 Sep;36(3):248-259.
- doi: 10.1186/s42826-020-00063-z
Differences in responsiveness of BALB/c substrains have been investigated in various fields, including diabetes induction, corpus callosum deficiency, virus-induced demyelinating disease, aggressive behavior and osteonecrosis. However, induction efficacy of skin... -
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- Comparative analysis of restraint stress-induced depressive-like phenotypes in C57BL/6N mice derived from three different sources
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Hwang DJ, Kwon KC, Hwang DY, Seo MS, Kim KS, Jung YS, Cho JY
- KMID: 2507237
- Lab Anim Res.
- 2020 Sep;36(3):239-247.
- doi: 10.1186/s42826-020-00062-0
C57BL/6NKorl mice are a novel mouse stock recently developed by the National Institute of Food and Drug Safety Evaluation in Korea. Extensive research into the nature of C57BL/6NKorl mice is... -
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- Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2
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Lee SH, Jee SW, Hwang DY, Kang JK
- KMID: 2507226
- Lab Anim Res.
- 2020 Sep;36(3):177-187.
- doi: 10.1186/s42826-020-00056-y
Human angiotensin-converting enzyme 2 (hACE2) has recently received a great attention due to it play a critical role as SARS-CoV receptor in the infection of human body. However, no further... -
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- Lymph node size and its association with nodal metastasis in ductal adenocarcinoma of the pancreas
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Shin J, Shin S, Lee JH, Song KB, Hwang DW, Kim HJ, Byun JH, Cho H, Kim SC, Hong SM
- KMID: 2506272
- J Pathol Transl Med.
- 2020 Sep;54(5):387-395.
- doi: 10.4132/jptm.2020.06.23
Background: Although lymph node metastasis is a poor prognostic factor in patients with pancreatic ductal adenocarcinoma (PDAC), our understanding of lymph node size in association with PDAC is limited. Increased... -
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- A Fully Immersive Virtual Reality Method for Upper Limb Rehabilitation in Spinal Cord Injury
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Lim DY, Hwang DM, Cho KH, Moon CW, Ahn SY
- KMID: 2505391
- Ann Rehabil Med.
- 2020 Aug;44(4):311-319.
- doi: 10.5535/arm.19181
Objective To determine whether a fully immersive virtual reality (VR) intervention combined with conventional rehabilitation (CR) can improve upper limb function more than CR alone in patients with spinal cord... -
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- Prognostic Predictability of American Joint Committee on Cancer 8th Staging System for Perihilar Cholangiocarcinoma: Limited Improvement Compared with the 7th Staging System
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Lee JW, Lee JH, Park Y, Lee W, Kwon J, Song KB, Hwang DW, Kim SC
- KMID: 2504467
- Cancer Res Treat.
- 2020 Jul;52(3):886-895.
- doi: 10.4143/crt.2020.023
Purpose This study was conducted to evaluate the prognostic values of the 7th and 8th American Joint Committee on Cancer (AJCC) staging systems for patients with resected perihilar cholangiocarcinoma (PHCC). Materials and... -
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- Suitability of the Aortic Neck Anatomy for Endovascular Aneurysm Repair in Korean Patients with Abdominal Aortic Aneurysm
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Hwang D, Kim J, Kim HK, Huh S
- KMID: 2503971
- Vasc Spec Int.
- 2020 Jun;36(2):71-81.
- doi: 10.5758/vsi.200016
Purpose: To evaluate the aortic neck anatomy in Korean patients with abdominal aortic aneurysms (AAAs). Materials and Methods: We examined computed tomography scans of 343 patients with AAAs (≥5.5 cm for... -
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- Clinical application of chromosomal microarray for pathogenic genomic imbalance in fetuses with increased nuchal translucency but normal karyotype
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Lee D, Go S, Na S, Park S, Ma J, Hwang D
- KMID: 2503607
- J Genet Med.
- 2020 Jun;17(1):21-26.
- doi: 10.5734/JGM.2020.17.1.21
Purpose: To evaluate the additive value of prenatal chromosomal microarray analysis (CMA) in assessing increased nuchal translucency (NT) (≥3.5 mm) with normal karyotype and the possibility of detecting clinically significant... -
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- Human equilibrative nucleoside transporter-1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression; do they have survival impact to pancreatic cancer?
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Hwang DW, Shin E, Cho JY, Han HS, Yoon YS
- KMID: 2500772
- Ann Hepatobiliary Pancreat Surg.
- 2020 May;24(2):127-136.
- doi: 10.14701/ahbps.2020.24.2.127
Backgrounds/Aims: Gemcitabine is still one of adjuvant options in chemotherapeutic agent for pancreatic ductal adenocarcinoma (PDAC). Integral membrane transporter protein and intracellular enzymes including human equilibrative nucleoside transporter 1 (hENT1),... -
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- Efficacy and Safety of Pembrolizumab in Patients with RefractoryAdvanced Biliary Tract Cancer: Tumor Proportion Score as a PotentialBiomarker for Response
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Kang J, Jeong JH, Hwang HS, Lee SS, Park DH, Oh DW, Song TJ, Kim KH, Hwang S, Hwang DW, Kim SC, Park Jh, Hong SM, Kim Kp, Ryoo BY, Yoo C
- KMID: 2500344
- Cancer Res Treat.
- 2020 Apr;52(2):594-603.
- doi: 10.4143/crt.2019.493
Purpose The current standard chemotherapy for advanced biliary tract cancer (BTC) has limited benefit, and novel therapies need to be investigated. Materials and Methods In this prospective cohort study, programmed death ligand-1 (PD-L1)–positive BTC... -
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- Validation of the 8th Edition of the American Joint Committee onCancer Staging System for Gallbladder Cancer and Implications forthe Follow-up of Patients without Node Dissection
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Sung YN, Song M, Lee JH, Song KB, Hwang DW, Ahn CS, Hwang S, Hong SM
- KMID: 2500331
- Cancer Res Treat.
- 2020 Apr;52(2):455-468.
- doi: 10.4143/crt.2019.271
Purpose The 8th edition of gallbladder cancer staging in the American Joint Committee on Cancer (AJCC) staging system changed the T and N categories. Materials and Methods In order to validate the new staging... -
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- Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice
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Park JW, Kim JE, Kang MJ, Choi HJ, Bae SJ, Hwang DY
- KMID: 2510421
- Lab Anim Res.
- 2020 Mar;36(1):28-35.
- doi: 10.1186/s42826-020-0036-7
To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and... -
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- Ovarian pregnancy rupture in second trimester manifesting mental change in pregnancy: a case report
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Hwang DW, Choi HW, Choi YY, Kim HS, Kim YA, Chun KC
- KMID: 2471760
- Obstet Gynecol Sci.
- 2020 Mar;63(2):209-212.
- doi: 10.5468/ogs.2020.63.2.209
Ovarian pregnancies comprise approximately 3% of ectopic pregnancies. Moreover, ovarian pregnancies in the second trimester are extremely rare. We herein present a case of ruptured ovarian pregnancy in the second... -
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- Prognostic factors predicting survival rate over 10 years of patients with intrahepatic cholangiocarcinoma after hepatic resection
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Ma CH, Hwang DW, Song KB, Kim SC, Shin SH, Lee JH
- KMID: 2471176
- Ann Surg Treat Res.
- 2020 Mar;98(3):116-123.
- doi: 10.4174/astr.2020.98.3.116
PURPOSE: Hepatic resection is considered as the optimal treatment for intrahepatic cholangiocarcinoma (IHCC); however, the survival rate after resection is low and the analysis of long-term (≥10 years) survivors is... -
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