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Far-infrared rays enhance mitochondrial biogenesis and GLUT3 expression under low glucose conditions in rat skeletal muscle cells

Seo Y, Kim YW, Lee D, Kim D, Kim K, Kim T, Baek C, Lee Y, Lee J, Lee H, Jang G, Jeong W, Choi J, Hwang D, Suh JS, Kim SW, Kim HK, Han J, Bang H, Kim JH, Zhou T, Ko JH

Far-infrared rays (FIR) are known to have various effects on atoms and molecular structures within cells owing to their radiation and vibration frequencies. The present study examined the effects of...
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Inflammatory responses of C57BL/6NKorl mice to dextran sulfate sodium-induced colitis: comparison between three C57BL/6 N sub-strains

Kim SH, Kwon D, Son SW, Jeong TB, Lee S, Kwak JH, Cho JY, Hwang DY, Seo MS, Kim KS, Jung YS

Background: Inflammatory bowel disease (IBD), including both Crohn’s disease and ulcerative colitis, are chronic human diseases that are challenging to cure and are often unable to be resolved. The inbred...
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Physiologic Assessment after Coronary Stent Implantation

Hwang D, Yang S, Zhang J, Koo BK

The presence of myocardial ischemia is a prerequisite for the benefit of coronary revascularization. In the cardiac catheterization laboratory, fractional flow reserve and non-hyperemic pressure ratios are used to define...
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Comparison of response to LPS-induced sepsis in three DBA/2 stocks derived from different sources

Park JW, Lee SJ, Kim JE, Kang MJ, Bae SJ, Choi YJ, Gong JE, Kim KS, Jung YS, Cho JY, Choi YS, Hwang DY, Song HK

Sepsis, one of the most fatal diseases in the world, is known to culminate in multiple organ failure due to an uncontrolled inflammatory response. Hence, the use of animal models...
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Association of Quantitative Flow Ratio with Lesion Severity and Its Ability to Discriminate Myocardial Ischemia

Dai N, Hwang D, Lee JM, Zhang J, Tong Y, Jeon KH, Paeng JC, Cheon GJ, Koo BK, Ge J

Background and Objectives: Quantitative flow ratio (QFR) is an angiography-based technique for functional assessment of coronary artery stenosis. This study investigated the response of QFR to different degree of stenosis...
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Long-Term Result of Tibioperoneal Trunk Bypass with an Autogenous Graft Using the Varicose Great Saphenous Vein for Acute Limb Ischemia

Kim HK, Hwang D, Huh S

For the management of acute limb ischemia (ALI) and multilevel arterial occlusive disease, tibial bypass using the saphenous vein has been considered a mainstay due to the long-term durability in...
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Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment

Kang MJ, Gong JE, Kim JE, Choi HJ, Bae SJ, Seo MS, Kim KS, Jung YS, Cho JY, Lim Y, Hwang DY

Differences in responsiveness of BALB/c substrains have been investigated in various fields, including diabetes induction, corpus callosum deficiency, virus-induced demyelinating disease, aggressive behavior and osteonecrosis. However, induction efficacy of skin...
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Comparative analysis of restraint stress-induced depressive-like phenotypes in C57BL/6N mice derived from three different sources

Hwang DJ, Kwon KC, Hwang DY, Seo MS, Kim KS, Jung YS, Cho JY

C57BL/6NKorl mice are a novel mouse stock recently developed by the National Institute of Food and Drug Safety Evaluation in Korea. Extensive research into the nature of C57BL/6NKorl mice is...
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Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2

Lee SH, Jee SW, Hwang DY, Kang JK

Human angiotensin-converting enzyme 2 (hACE2) has recently received a great attention due to it play a critical role as SARS-CoV receptor in the infection of human body. However, no further...
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Lymph node size and its association with nodal metastasis in ductal adenocarcinoma of the pancreas

Shin J, Shin S, Lee JH, Song KB, Hwang DW, Kim HJ, Byun JH, Cho H, Kim SC, Hong SM

Background: Although lymph node metastasis is a poor prognostic factor in patients with pancreatic ductal adenocarcinoma (PDAC), our understanding of lymph node size in association with PDAC is limited. Increased...
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A Fully Immersive Virtual Reality Method for Upper Limb Rehabilitation in Spinal Cord Injury

Lim DY, Hwang DM, Cho KH, Moon CW, Ahn SY

Objective To determine whether a fully immersive virtual reality (VR) intervention combined with conventional rehabilitation (CR) can improve upper limb function more than CR alone in patients with spinal cord...
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Prognostic Predictability of American Joint Committee on Cancer 8th Staging System for Perihilar Cholangiocarcinoma: Limited Improvement Compared with the 7th Staging System

Lee JW, Lee JH, Park Y, Lee W, Kwon J, Song KB, Hwang DW, Kim SC

Purpose This study was conducted to evaluate the prognostic values of the 7th and 8th American Joint Committee on Cancer (AJCC) staging systems for patients with resected perihilar cholangiocarcinoma (PHCC). Materials and...
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Suitability of the Aortic Neck Anatomy for Endovascular Aneurysm Repair in Korean Patients with Abdominal Aortic Aneurysm

Hwang D, Kim J, Kim HK, Huh S

Purpose: To evaluate the aortic neck anatomy in Korean patients with abdominal aortic aneurysms (AAAs). Materials and Methods: We examined computed tomography scans of 343 patients with AAAs (≥5.5 cm for...
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Clinical application of chromosomal microarray for pathogenic genomic imbalance in fetuses with increased nuchal translucency but normal karyotype

Lee D, Go S, Na S, Park S, Ma J, Hwang D

Purpose: To evaluate the additive value of prenatal chromosomal microarray analysis (CMA) in assessing increased nuchal translucency (NT) (≥3.5 mm) with normal karyotype and the possibility of detecting clinically significant...
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Human equilibrative nucleoside transporter-1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression; do they have survival impact to pancreatic cancer?

Hwang DW, Shin E, Cho JY, Han HS, Yoon YS

Backgrounds/Aims: Gemcitabine is still one of adjuvant options in chemotherapeutic agent for pancreatic ductal adenocarcinoma (PDAC). Integral membrane transporter protein and intracellular enzymes including human equilibrative nucleoside transporter 1 (hENT1),...
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Efficacy and Safety of Pembrolizumab in Patients with RefractoryAdvanced Biliary Tract Cancer: Tumor Proportion Score as a PotentialBiomarker for Response

Kang J, Jeong JH, Hwang HS, Lee SS, Park DH, Oh DW, Song TJ, Kim KH, Hwang S, Hwang DW, Kim SC, Park Jh, Hong SM, Kim Kp, Ryoo BY, Yoo C

Purpose The current standard chemotherapy for advanced biliary tract cancer (BTC) has limited benefit, and novel therapies need to be investigated. Materials and Methods In this prospective cohort study, programmed death ligand-1 (PD-L1)–positive BTC...
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Validation of the 8th Edition of the American Joint Committee onCancer Staging System for Gallbladder Cancer and Implications forthe Follow-up of Patients without Node Dissection

Sung YN, Song M, Lee JH, Song KB, Hwang DW, Ahn CS, Hwang S, Hong SM

Purpose The 8th edition of gallbladder cancer staging in the American Joint Committee on Cancer (AJCC) staging system changed the T and N categories. Materials and Methods In order to validate the new staging...
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Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice

Park JW, Kim JE, Kang MJ, Choi HJ, Bae SJ, Hwang DY

To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and...
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Ovarian pregnancy rupture in second trimester manifesting mental change in pregnancy: a case report

Hwang DW, Choi HW, Choi YY, Kim HS, Kim YA, Chun KC

Ovarian pregnancies comprise approximately 3% of ectopic pregnancies. Moreover, ovarian pregnancies in the second trimester are extremely rare. We herein present a case of ruptured ovarian pregnancy in the second...
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Prognostic factors predicting survival rate over 10 years of patients with intrahepatic cholangiocarcinoma after hepatic resection

Ma CH, Hwang DW, Song KB, Kim SC, Shin SH, Lee JH

PURPOSE: Hepatic resection is considered as the optimal treatment for intrahepatic cholangiocarcinoma (IHCC); however, the survival rate after resection is low and the analysis of long-term (≥10 years) survivors is...
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