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Clinical Implications of Circulating Tumor DNA from Ascites and Serial Plasma in Ovarian Cancer

Han MR, Lee SH, Park JY, Hong H, Ho JY, Hur SY, Choi YJ

Purpose The purpose of this study was to identify the clinical utility of circulating tumor DNA (ctDNA) from ascites and serial plasma samples from epithelial ovarian cancer (EOC) patients. Materials and Methods Using...
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Risk factors for cytological progression in HPV 16 infected women with ASC-US or LSIL: The Korean HPV cohort

So KA, Kim SA, Lee YK, Lee IH, Lee KH, Rhee JE, Kee MK, Cho CH, Hong SR, Hwang CS, Jeong MS, Kim KT, Ki M, Hur SY, Park JS, Kim TJ

OBJECTIVE: This study was to identify the risk factors for cytological progression in women with atypical squamous cells of undetermined significance (ASC-US) or low-grade squamous intraepithelial lesions (LSIL). METHODS: We analyzed...
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An Open-Label, Randomized, Parallel, Phase II Trial to Evaluate the Efficacy and Safety of a Cremophor-Free Polymeric Micelle Formulation of Paclitaxel as First-Line Treatment for Ovarian Cancer: A Korean Gynecologic Oncology Group Study (KGOG-3021)

Lee SW, Kim YM, Cho CH, Kim YT, Kim SM, Hur SY, Kim JH, Kim BG, Kim SC, Ryu HS, Kang SB

PURPOSE: Genexol-PM is a biodegradable cremophor EL–free polymeric micelle formulation of paclitaxel. Here,we compared efficacy and safety of Genexol-PM plus carboplatin versus Genexol plus carboplatin for ovarian cancer treatment. MATERIALS AND...
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Clinical Significance of an HPV DNA Chip Test with Emphasis on HPV-16 and/or HPV-18 Detection in Korean Gynecological Patients

Yeo MK, Lee A, Hur SY, Park JS

BACKGROUND: Human papillomavirus (HPV) is a major risk factor for cervical cancer. METHODS: We evaluated the clinical significance of the HPV DNA chip genotyping assay (MyHPV chip, Mygene Co.) compared with...
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DNA methylation in human papillomavirus-infected cervical cells is elevated in high-grade squamous intraepithelial lesions and cancer

Kim MK, Lee IH, Lee KH, Lee YK, So KA, Hong SR, Hwang CS, Kee MK, Rhee JE, Kang C, Hur SY, Park JS, Kim TJ

OBJECTIVE: DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap...
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Can human papillomavirus (HPV) genotyping classify non-16/18 high-risk HPV infection by risk stratification?

Sung YE, Ki EY, Lee YS, Hur SY, Lee A, Park JS

OBJECTIVE: Infection with high-risk genotypes of human papillomavirus (HR-HPV) is the major cause of invasive cervical cancers. HPV-16 and HPV-18 are known to be responsible for two-thirds of all invasive...
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A Clinicopathological Review of Pulmonary Metastasis from Uterine Cervical Cancer

Ki EY, Lee KH, Park JS, Hur SY

PURPOSE: The purpose of this study was to investigate the clinicopathological features of pulmonary metastasis from cervical cancer. MATERIALS AND METHODS: We reviewed the medical records of 56 patients with cervical...
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Practice guidelines for the early detection of cervical cancer in Korea: Korean Society of Gynecologic Oncology and the Korean Society for Cytopathology 2012 edition

Lee JK, Hong JH, Kang S, Kim DY, Kim BG, Kim SH, Kim YM, Kim JW, Kim JH, Kim TJ, Kim HJ, Kim HS, Ryu HS, Song JY, Ahn HS, Yoo CW, Yoon HK, Lee KH, Lee A, Lee Y, Lee IH, Lee JW, Lee TS, Lim MC, Chang SJ, Chung HH, Ju W, Joo HJ, Hur SY, Hong SR, Nam JH

The consensus guideline development committee of Korean Society of Gynecologic Oncology was reconvened in March 2012. The committee consisted of 36 experts representing 12 university hospitals and professional organizations. The...
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Establishment of a Korea HPV cohort study

Lee WC, Lee SY, Koo YJ, Kim TJ, Hur SY, Hong SR, Kim SS, Kee MK, Rhee JE, Lee JS, Choi HS, Cho CH, Kim KT, Park JS

We have designed a five-year multicentre prospective cohort study in women who are both human papillomavirus (HPV)-positive with either atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial...
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Clinical analysis of intra-operative frozen section proven borderline tumors of the ovary

Kim JH, Kim TJ, Park YG, Lee SH, Lee CW, Song MJ, Lee KH, Hur SY, Bae SN, Park JS

OBJECTIVE: We have assessed the accuracy of frozen section diagnosis and the outcomes of misdiagnosis in borderline tumors of the ovary (BTO) according to frozen section. METHODS: All pathology reports...
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Epithelial ovarian cancer in patients under 20 years of age

Choi JH, Hur SY, Bae SN, Park SS, Namkoong S, Lee JM

  • KMID: 1479863
  • Korean J Obstet Gynecol.
  • 2008 Aug;51(8):850-857.
OBJECTIVE: Epithelial ovarian cancer is the most common cause of death due to gynecologic malignancies in adults, but is rare in children and adolescents. This is a report of series...
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A case of inguinal lymph node squamous cell carcinoma of unknown origin, accompanied with carcinoma in situ of cervix

Lee SH, Kim MJ, Lee HJ, Kim SJ, Park JS, Hur SY

Metastatic Cancer of Unknown Primary Site (CUP) accounts for approximately 3-5% of all malignant neoplasms. CUP represents a heterogeneous group of metastatic tumors for which no primary site can be...
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Conservative treatment of endometrial adenocarcinoma in young women with hormone therapy

Hur SY

  • KMID: 2273338
  • Korean J Obstet Gynecol.
  • 2008 May;51(5):492-503.
Endometrial cancer is the ninth common cancer in women and the third common gynecologic cancer in Korea. Although it is primarily a disease of the postmenopausal female, 3-5% of patients...
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Induction of apoptosis by the kinase inhibitor flavopiridol in human ovarian cancer cell lines

Hur SY, Lee JM

OBJECTIVE: Flavopiridol that inhibits cyclin-dependent kinase, can cause cell cycle arrest, induce apoptosis in human tumor cell lines. In the present study, we investigated apoptotic effects of flavopiridol and the...
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A case of choledochal cyst diagnosed and conservatively treated during pregnancy

Nam SY, Kim MJ, Park IY, Kim HJ, Hur SY, Shin JC, Kim SJ

  • KMID: 2273553
  • Korean J Obstet Gynecol.
  • 2008 Dec;51(12):1499-1503.
Choledocal cyst are cystic dilatations of the biliary tree varying in location from the ampulla of vater to the intrahepatic bile ducts. The majority of the cases are diagnosed during...
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Sexual behavior of Korean young women: preliminary study for the introducing of HPV prophylactic vaccine

Kim CJ, Kim BG, Kim SC, Kim YT, Kim YM, Park SY, Song YS, Lee NW, Lee WC, Lee JK, Cho CH, Hur SY, Park JS, Lee KW

  • KMID: 2244550
  • Korean J Gynecol Oncol.
  • 2007 Sep;18(3):209-218.
OBJECTIVE: The decision of optimal age for administration of recently approved prophylactic human papillomavirus (HPV) vaccines in the world depend on the basis of the sexual behavior of each countries....
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Analysis of HLA-G expression in preeclampsia and intrauterine growth restriction

Suh MJ, Moon JM, Hur SY, Kim SJ

  • KMID: 1870354
  • Korean J Obstet Gynecol.
  • 2007 Mar;50(3):439-448.
OBJECTIVE: To determine whether soluble HLA-G protein levels in plasma and/or HLA-G protein in placental tissues differ between women with gestational complications (preeclampsia and/or intrauterine growth restriction, IUGR) and women...
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A case of chemoresistant placental site trophoblastic tumor in a patient who wants to remain fertile

Cho HJ, Kwack HS, Nam SY, Kang YH, Kim MJ, Lim HW, Lee HJ, Kim SJ, Hur SY

  • KMID: 2244543
  • Korean J Gynecol Oncol.
  • 2007 Dec;18(4):373-378.
Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic tumor (GTT) that has different behavior in disease process. The hysterectomy is general for PSTT, but hysterectomy is...
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Recommendation guideline of Korean Society of Gynecologic Oncology and Colposcopy for quadrivalent human papillomavirus vaccine

Kim BG, Lee NW, Kim SC, Kim YT, Kim YM, Kim CJ, Park SY, Song YS, Lee JK, Lee WC, Cho NH, Cho CH, Hur SY, Park JS, Lee KW, Korean Society of Gynecologic Oncology and Colposcopy Cervical Cancer Prevention Committee Task Force Team

  • KMID: 2244530
  • Korean J Gynecol Oncol.
  • 2007 Dec;18(4):259-283.
Genital HPV infection is the most common sexually transmitted infection, but the majority of infections are self-limited. However, persistent infection with high-risk types can cause cervical cancer in women, which...
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The significance of maternal serum and umbilical cord blood leptin concentration with intrauterine fetal growth restriction and/or preeclampsia

Lee GS, Kil KC, Lee Y, Ahn HY, Hur SY, Shin EY, Shin JC, Lew YO

  • KMID: 2077788
  • Korean J Obstet Gynecol.
  • 2007 Oct;50(10):1336-1343.
OBJECTIVE: To ascertain whether fetal growth restriction with or without preeclampsia is associated with alteration of leptin concentration in maternal and umbilical cord serum. METHODS: Maternal serum and umbilical cord blood...
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