Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

27 results
Display

Gemigliptin Inhibits Interleukin-1β–Induced Endothelial-Mesenchymal Transition via Canonical-Bone Morphogenetic Protein Pathway

Hong OK, Lee SS, Yoo SJ, Lee MK, Kim MK, Baek KH, Song KH, Kwon HS

Background: Endothelial-to-mesenchymal transition (EndMT) contributes to inflammatory conditions inducing conversion of endothelial cells (ECs) into activated fibroblasts, promoting fibrotic diseases. Pro-inflammatory cytokine is the most potent inducer of EndMT. We...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Association between Pancreatic Steatosis and Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients

Jeong JS, Kim MK, Han KD, Hong OK, Baek KH, Song KH, Chung DJ, Lee JM, Kwon HS

BACKGROUND: Whether pancreatic steatosis has a local or systemic effect, like ectopic fat of other major organs, remains unknown. Data on the influence of pancreatic steatosis on microvascular complication are...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
High glucose and palmitate increases bone morphogenic protein 4 expression in human endothelial cells

Hong OK, Yoo SJ, Son JW, Kim MK, Baek KH, Song KH, Cha BY, Jo H, Kwon HS

Here, we investigated whether hyperglycemia and/or free fatty acids (palmitate, PAL) aff ect the expression level of bone morphogenic protein 4 (BMP4), a proatherogenic marker, in endothelial cells and the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Chronic Alcohol Consumption Results in Greater Damage to the Pancreas Than to the Liver in the Rats

Lee SS, Hong OK, Ju A, Kim MJ, Kim BJ, Kim SR, Kim WH, Cho NH, Kang MI, Kang SK, Kim DJ, Yoo SJ

Alcohol consumption increases the risk of type 2 diabetes. However, its effects on prediabetes or early diabetes have not been studied. We investigated endoplasmic reticulum (ER) stress in the pancreas...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Angiotensin II Inhibits Insulin Binding to Endothelial Cells

Oh SJ, Ha WC, Lee JI, Sohn TS, Kim JH, Lee JM, Chang SA, Hong OK, Son HS

BACKGROUND: Insulin-mediated glucose uptake in insulin target tissues is correlated with interstitial insulin concentration, rather than plasma insulin concentration. Therefore, insulin delivery to the interstitium of target tissues is very...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Flow Cytometric Analysis of Cultured Adult Neural Stem Cells from Guinea Pig Spiral Ganglion

Kim YH, Kim CH, Park KH, Park SN, Choi MY, Hong OK, Kim JH, Cho SJ, Kim JH, Chang KH, Yeo SW

BACKGROUND AND OBJECTIVES: To make stem cell therapy successful as one of treatment options for sensorineural hearing loss, it is essential to culture and obtain sufficient amounts of adult neural...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The effects of mixed chimerism conducted by natural killer cell depletion with non myeloablation on islet allograft rejection

Park HS, Cho SG, Park CG, Hong OK, Kim JW, Kim BR, Yoon KH

  • KMID: 2331785
  • J Korean Diabetes Assoc.
  • 2006 Jan;30(1):54-63.
BACKGROUND: Because of the shortage of human pancreas and immunorejection, very small fraction of patients with type 1 diabetes can be treated with islet transplantation. The immune tolerance induction for...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The long-term effect of ramipril on Gialpha2-protein and Protein Tyrosine Phosphatase 1B in an animal model of type 2 diabetes(OLETF rat)

Lee JM, Hong OK, Kwon HS, Moon SD, Chang SA, Son HS, Yoon KH, Cha BY, Kang SK

  • KMID: 2331782
  • J Korean Diabetes Assoc.
  • 2006 Jan;30(1):25-38.
BACKGROUND: The regulation of tyrosine phosphorylation/dephosphorylation is an important mechanism in various intracellular metabolism. Also impaired insulin signal transduction is important in pathogenesis of type 2 diabetes. It has been...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pancreatic Stellate Cell Activation by High Glucose and Its Effect on Angiotensin II

Ko SH, Hong OK, Lee MK, Park EH, Lee SS, Ahn YB, Song KH, Cha BY, Son HY, Kim MJ, Jung IK, Yoon KH

  • KMID: 2177758
  • J Korean Diabetes Assoc.
  • 2005 Jul;29(4):304-314.
BACKGROUND: Pancreatic stellate cells (PSCs) are known to be related to pancreatic inflammation and fibrosis, and are the result of extracellular matrix(ECM) protein synthesis. Recent studies have shown that blockade...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Induction of Immune Tolerance by Macrochimerism: Preliminary Study for Overcome of Islet Allograft Rejection

Hong OK, Kim SJ, Park CG, Chung CW, Kwon HS, Choi YH, Cha BY, Son HY, Yoon KH

  • KMID: 2331759
  • J Korean Diabetes Assoc.
  • 2005 Mar;29(2):112-121.
BACKGROUND: Recently islet transplantation(TPx) has achieved remarkable results while it is not the ultimate solution yet because of a serious shortage of human pancreases, immune rejection and recurrence of autoimmunity....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Characterization of Preadipocyte factor-1 (Pref-1) Expressing Pancreatic Cells

Rhee M, Suh SH, Yang YJ, Kim JW, Jeon SY, Hong OK, Ko SH, Choi YH, Cha BY, Son HY, Yoon KH

  • KMID: 2177738
  • J Korean Diabetes Assoc.
  • 2005 Nov;29(6):507-516.
BACKGROUND: Preadipocyte factor-1/Delta-like 1(Pref-1/Dlk1) is a type I membrane protein that has six epidermal growth factor (EGF)-like repeats in its extracellular and a short cytoplasmic domain. It is widely expressed...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effects of Dexamethasone on the Expansion and Transdifferentiation of Transplanted Porcine Neonatal Pancreas Cell Clusters into beta-cells in Normal Nude Mice

Yang JH, Suh SH, Jeon SY, Hong OK, Yoon KH

  • KMID: 2008164
  • J Korean Diabetes Assoc.
  • 2004 Oct;28(5):356-366.
BACKGROUND: Several studies have suggested that glucocorticoid has an influence on the development and function of the -cells. Thus, we undertook this study to determine whether exposure to dexamethasone...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effects of High Glucose, Insulin and TGF-beta 1 on Proliferation and Differentiation of the Pancreatic Stellate Cells

Hong OK, Kwon HS, Yeom KH, Lee M, Yang JH, Ko SH, Yoo SJ, Son HS, Yoon KH, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 1768000
  • J Korean Diabetes Assoc.
  • 2003 Jun;27(3):228-240.
BACKGROUND: Although chronic pancreatitis gives rise to fibrosis of pancreatic exocrine tissue, and type 2 diabetes is accompanied by pancreatic fibrosis, the mechanisms of fibrogenesis in the pancreas have been...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Effect of Nitric Oxide on Insulin Binding and Insulin Receptor Recycling in Bovine Aortic Endothelial Cells

Kwon HS, Hong OK, Kim HS, Lee JM, Kim SR, Moon SD, Jang SA, Son HS, Yoon KH, Kang MI, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 1767999
  • J Korean Diabetes Assoc.
  • 2003 Jun;27(3):213-227.
BACKGROUND: The coexistence of insulin resistance and endothelial dysfunction is commonly observed in a variety of metabolic and cardiovascular disorders, including athero-sclerosis and type 2 diabetes mellitus. Because nitric oxide...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of Gi-proteins on Insulin Binding, Internalization and Recycling of Insulin Receptor in Bovine Aorta Endothelial Cell

Kwon HH, Son HS, Lee JM, Ko SH, Hong OK, Moon SD, Chang SA, Yoon KH, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 2008104
  • J Korean Diabetes Assoc.
  • 2003 Feb;27(1):26-38.
BACKGROUND: Guanine nucleotide binding proteins (G-proteins) play important roles in the hormonal actions of many signal transduction systems. Possible roles for the Gi-protein in insulin action have been suggested. It...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
3-Dimensional Long Term Culture of Monolayer Cultured Dispersed Neonatal Porcine Pancreas Cells (NPCC)

Suh SH, Yoon KH, Kwon HS, Hong OK, Lee JM, Song KH, Yoo SJ, Son HS, Kang MI, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 2008281
  • J Korean Diabetes Assoc.
  • 2002 Oct;26(5):383-395.
BACKGROUND: We have reported porcine neonatal pancreas cell clusters (NPCCs) to be useful clinical alternative due to their growth potential and convenience. However, to apply the porcine NPCCs in human...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of Overexpression of Gi Proteins on Insulin Actions in 3T3-L1 Adipocytes

Son HS, Cha BY, Moon SD, Lee JM, Hong OK, Chang SA, Ahn YB, Yoon KH, Lee KW, Son HY, Kang SK

  • KMID: 1905886
  • J Korean Diabetes Assoc.
  • 2000 Aug;24(4):404-412.
BACKGROUND: It has been reported that G proteins are involved in biological actions of insulin. Especially, Gi protein is more associated with insulin actions than Gs proteins. Gi protein has...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Changes in the Amount and Function of Gi Protein in the Liver Cells of Streptozotocin-Induced Diabetic Rats

Ock SM, Son HS, Hong OK, Lee JM, Kim SR, Chang SA, Yoon KH, Kang MI, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 1767982
  • J Korean Diabetes Assoc.
  • 2000 Dec;24(6):666-677.
BACKGROUND: The functional and expressional changes of Gi proteins in diabetes have been investigated extensively, no agreement has been reached in the results. Moreover, studies using rats with different diabetic...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Formation of Multimedia Medical Information Web DB by Frequent Q and A in Internet Hospital

Hong OJ, Park SI, Choi KC, Park SN, Kim SJ, Suh SW, Kim SH, Hwang JH, Kim YB, Park HM

  • KMID: 2329802
  • J Korean Soc Med Inform.
  • 1999 Dec;5(3):159-167.
Over Past years people have known rich medical information and knowledge through mass-media. It is needed to develop medical database, which makes people get proper medical information, So we made...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Medical Counseling by Interact via Daily Newspaper

Kim YB, Hong OJ, Han SH, Choi KC, Park SN, Lee SM, Ha KC, La DG

  • KMID: 2329731
  • J Korean Soc Med Inform.
  • 1998 Jun;4(1):57-63.
Recently the change in medical informatics enabled us to use medical information whenever we want and wherever we are. There are many homepages on the web, which provide hospital information,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr