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Long-term Prognosis of Localized Lymphoid Hyperplasia of the Rectum

Hong JT, Kim ER, Park SW, Kim JW, Hong SN, Chang DK, Kim YH, Cho JH

Background/Aims: Although localized lymphoid hyperplasia (LLH) of the rectum is occasionally observed, its clinical implications are unclear. This study aimed to investigate the clinical course and significance of LLH of...
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Hypoxia Pretreatment Promotes Chondrocyte Differentiation of Human Adipose-Derived Stem Cells via Vascular Endothelial Growth Factor

Hwang OK, Noh YW, Hong JT, Lee JW

BACKGROUND: Human adipose tissue-derived stem cells (ADSCs) are attractive multipotent stem cell sources with therapeutic potential in various fields requiring repair and regeneration, such as acute and chronically damaged tissues....
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PEGylated Erythropoietin Protects against Brain Injury in the MCAO-Induced Stroke Model by Blocking NF-κB Activation

Im JH, Yeo IJ, Hwang CJ, Lee KS, Hong JT

Cerebral ischemia exhibits a multiplicity of pathophysiological mechanisms. During ischemic stroke, the reactive oxygen species (ROS) concentration rises to a peak during reperfusion, possibly underlying neuronal death. Recombinant human erythropoietin...
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Epidemiology of C5 Palsy after Cervical Spine Surgery: a 21-Center Study

Oh JK, Hong JT, Kang DH, Kim SW, Kim SW, Kim YJ, Chung CK, Shin JJ, Yi S, Lee JK, Lee JH, Lee CH, Lee HJ, Chun HJ, Cho DC, Cho YE, Jin YJ, Choi KC, Han IH, Hyun SJ, Hur JW, Kim KJ

OBJECTIVE: C5 palsy is a severe complication after cervical spine surgery, the pathophysiology of which remains unclear. This multicenter study investigated the incidence of C5 palsy following cervical spine surgery...
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Limonene Inhibits Methamphetamine-Induced Sensitizations via the Regulation of Dopamine Receptor Supersensitivity

Gu SM, Kim SY, Lamichhane S, Hong JT, Yun J

Limonene is a cyclic terpene found in citrus essential oils and inhibits methamphetamine-induced locomotor activity. Drug dependence is a severe neuropsychiatric condition that depends in part on changes in neurotransmission...
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Combination Effect of Titrated Extract of Centella asiatica and Astaxanthin in a Mouse Model of Phthalic Anhydride-Induced Atopic Dermatitis

Park JH, Yeo IJ, Jang JS, Kim KC, Park MH, Lee HP, Han SB, Hong JT

PURPOSE: In our previous study, we demonstrated that both titrated extract of Centella asiatica (TECA) and astaxanthin (AST) have anti-inflammatory effects in a 5% phthalic anhydride (PA) mouse model of...
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Human Craniovertebral Alignment as a “Tertiary Curvature”

Hong JT

No abstract available.
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Change of Extracellular Glutamate Level in Striatum during Deep Brain Stimulation of the Entopeduncular Nucleus in Rats

Lee HJ, Sung JH, Hong JT, Kim IS, Yang SH, Cho CB

OBJECTIVE: Globus pallidus interna (GPi) is acknowledged as an essential treatment for advanced Parkinson’s disease (PD). Nonetheless, the neurotransmitter study about its results is undiscovered. The goal of this research...
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Sleep-Aids Derived from Natural Products

Hu Z, Oh S, Ha TW, Hong JT, Oh KW

Although drugs such as barbiturates and benzodiazepines are often used for the treatment of insomnia, they are associated with various side effects such as habituations, tolerance and addiction. Alternatively, natural...
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Comparison of Morphological Characteristics of the Subaxial Cervical Spine between Athetoid Cerebral Palsy and Normal Control

Kim JY, Kwon JY, Kim MS, Lee JJ, Kim IS, Hong JT

OBJECTIVE: To compare the morphometry of subaxial cervical spine between cerebral palsy (CP) and normal control. METHODS: We retrospectively analyzed 72 patients with CP, as well as 72 patients from normal...
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Ureteral catheters for colorectal surgery: Influence on operative times and complication outcomes: An observational study

Chong JT, Kan KM, Phillips C, Greenstein A

PURPOSE: Placement of pre-operative ureteral catheters for colorectal surgery can aid in the identification of ureteral injuries. This study investigates whether simultaneous ureteral catheterization with surgery skin preparation can minimize...
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Horizontal Stent Assisted Coiling of Wide Neck Basilar Tip Aneurysm: Comparison of Two Cases

Kim YJ, Sung JH, Hong JT, Lee SW

Currently, endovascular coiling is a popular treatment for basilar tip aneurysms, which usually involve a wide neck. Serious complications can occur when the posterior cerebral artery (PCA) originating from a...
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Inhibitory Effect of Carnosol on Phthalic Anhydride-Induced Atopic Dermatitis via Inhibition of STAT3

Lee DY, Hwang CJ, Choi JY, Park MH, Song MJ, Oh KW, Son DJ, Lee SH, Han SB, Hong JT

Carnosol is a phenolic antioxidant present in rosemary (Rosmarinus officinalis). It is known for anti-inflammatory effects, analgesic activity and anti-cancer effects. However, no study has been dedicated yet to its...
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Rosmarinic Acid Potentiates Pentobarbital-Induced Sleep Behaviors and Non-Rapid Eye Movement (NREM) Sleep through the Activation of GABA(A)-ergic Systems

Kwon YO, Hong JT, Oh KW

It has been known that RA, one of major constituents of Perilla frutescens which has been used as a traditional folk remedy for sedation in oriental countries, shows the anxiolytic-like...
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Striatal Glutamate and GABA after High Frequency Subthalamic Stimulation in Parkinsonian Rat

Lee KJ, Shim I, Sung JH, Hong JT, Kim IS, Cho CB

OBJECTIVE: High frequency stimulation (HFS) of the subthalamic nucleus (STN) is recognized as an effective treatment of advanced Parkinson’s disease. However, the neurochemical basis of its effects remains unknown. The...
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Prevalence of Neuropathic Pain and Patient-Reported Outcomes in Korean Adults with Chronic Low Back Pain Resulting from Neuropathic Low Back Pain

Kim JH, Hong JT, Lee CS, Kim KS, Suk KS, Kim JH, Park YS, Chang BS, Jun DS, Kim YH, Lee JH, Min WK, Lee JS, Park SY, Oh IS, Hong JY, Shin HC, Kim WK, Kim JH, Lee JK, Kim IS, Ha Y, Im SB, Kim SW, Han IH, Shin JJ, Rim BC, Seo BJ, Kim YJ, Lee J

STUDY DESIGN: A noninterventional, multicenter, cross-sectional study. PURPOSE: We investigated the prevalence of neuropathic pain (NP) and patient-reported outcomes (PROs) of the quality of life (QoL) and functional disability in Korean...
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Piperidylmethyloxychalcone improves immune-mediated acute liver failure via inhibiting TAK1 activity

Park SH, Kwak JA, Jung SH, Ahn B, Cho WJ, Yun CY, Na CS, Hwang BY, Hong JT, Han SB, Kim Y

Mice deficient in the toll-like receptor (TLR) or the myeloid differentiation factor 88 (MyD88) are resistant to acute liver failure (ALF) with sudden death of hepatocytes. Chalcone derivatives from medicinal...
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Sinomenine, an Alkaloid Derived from Sinomenium acutum Potentiates Pentobarbital-Induced Sleep Behaviors and Non-Rapid Eye Movement (NREM) Sleep in Rodents

Yoo JH, Ha TW, Hong JT, Oh KW

Sinomenium acutum has been long used in the preparations of traditional medicine in Japan, China and Korea for the treatment of various disorders including rheumatism, fever, pulmonary diseases and mood...
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Effectiveness and Safety of Mechanical Thrombectomy with Stent Retrievers in Basilar Artery Occlusion: Comparison with Anterior Circulation Occlusions

Hu SY, Yi HJ, Lee DH, Hong JT, Sung JH, Lee SW

OBJECTIVE: Acute basilar artery occlusion (BAO) is associated with severe neurological dysfunction and high mortality rates. The benefits of mechanical thrombectomy in BAO have not been explored in recent clinical...
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Potentiation of decursinol angelate on pentobarbital-induced sleeping behaviors via the activation of GABA(A)-ergic systems in rodents

Woo JH, Ha TW, Kang JS, Hong JT, Oh KW

Angelicae Gigantis Radix (AGR, Angelica gigas) has been used for a long time as a traditional folk medicine in Korea and oriental countries. Decursinol angelate (DCA) is structurally isomeric decursin,...
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