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Cathelicidin-related Antimicrobial Peptide Contributes to Host Immune Responses Against Pulmonary Infection with Acinetobacter baumannii in Mice

Kang MJ, Jang AR, Park JY, Ahn JH, Lee TS, Kim DY, Jung DH, Song EJ, Hong JJ, Park JH

Acinetobacter baumannii is known for its multidrug antibiotic resistance. New approaches to treating drug-resistant bacterial infections are urgently required. Cathelicidin-related antimicrobial peptide (CRAMP) is a murine antimicrobial peptide that exerts...
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Single-institution analysis of willingness of waitlist patients to undergo kidney transplantation with expanded criteria brain-dead donors

Hong JJ, Lee SR, Lee AY, Woo JW, Park SB, Hwang S, Kim YH

Background: The waitlist period for kidney transplantation (KT) has been increasing due to intractable shortage of brain-dead donors in Korea. To solve this organ shortage issue, KT cases with expanded...
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Simultaneous liver-kidney transplantation: A single-center experience in Korea

Kim M, Hwang S, Ahn CS, Moon DB, Ha TY, Song GW, Jung DH, Shin S, Kim YH, Ha HS, Hong JJ, Kim IO, Han DJ, Lee SG

Backgrounds/Aims: Simultaneous liver and kidney transplantation (SLKT) has been established as the treatment of choice for patients with concurrent end‐stage liver and end‐stage kidney diseases. The objective of this study...
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Rapid Whole-genome Sequencing of Zika Viruses using Direct RNA Sequencing

Kim JH, Kim J, Koo BS, Oh H, Hong JJ, Hwang ES

Zika virus (ZIKV) is one of the pathogens which is transmitted world widely, but there are no effective drugs and vaccines. Whole genome sequencing (WGS) of viruses could be applied...
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Increased CD68/TGFβ Co-expressing Microglia/Macrophages after Transient Middle Cerebral Artery Occlusion in Rhesus Monkeys

Yeo HG, Hong JJ, Lee Y, Yi KS, Jeon CY, Park J, Won J, Seo J, Ahn YJ, Kim K, Baek SH, Hwang EH, Kim G, Jin YB, Jeong KJ, Koo BS, Kang P, Lim KS, Kim SU, Huh JW, Kim YH, Son Y, Kim JS, Choi CH, Cha SH, Lee SR

The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in...
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Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling

Park J, Seo J, Won J, Yeo HG, Ahn YJ, Kim K, Jin YB, Koo BS, Lim KS, Jeong KJ, Kang P, Lee HY, Baek SH, Jeon CY, Hong JJ, Huh JW, Kim YH, Park SJ, Kim SU, Lee DS, Lee SR, Lee Y

Mitochondria continuously fuse and divide to maintain homeostasis. An impairment in the balance between the fusion and fission processes can trigger mitochondrial dysfunction. Accumulating evidence suggests that mitochondrial dysfunction is...
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Difficulties in End-of-Life Care and Educational Needs of Intensive Care Unit Nurses: A Mixed Methods Study

Kim HS, Choi EK, Kim TH, Yun HY, Kim EJ, Hong JJ, Hong JA, Kim GA, Kim SH

PURPOSE: This study aimed to identify the difficulties with end-of-life care (EOLC) experienced by intensive care unit (ICU) nurses and to investigate their educational needs for EOLC. METHODS: This study aimed...
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Assessment of patient safety and the efficiency of facility utilization following simplified ultra-rapid intravenous infusion of hepatitis B immunoglobulin in a high-volume liver transplantation center

Jeong IJ, Hwang S, Jung DH, Song GW, Park GC, Ahn CS, Moon DB, Kim KH, Ha TY, Ha HS, Hong JJ, Kim IO, Lee SG

BACKGROUNDS/AIMS: This study intended to evaluate patient safety and efficiency of facility utilization following simplified ultra-rapid intravenous infusion of hepatitis B immunoglobulin (HBIG) in recipients of hepatitis B virus-associated adult...
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Evaluation of fecal microbiomes associated with obesity in captive cynomolgus monkeys (Macaca fascicularis)

Koo BS, Hwang EH, Kim G, Oh H, Son Y, Lee D, Lim KS, Kang P, Lee S, Lee HY, Jeong KJ, Lee Y, Baek SH, Jeon CY, Park SJ, Kim YH, Huh JW, Jin YB, Kim SU, Lee SR, Hong JJ

Microorganisms play important roles in obesity; however, the role of the gut microbiomes in obesity is controversial because of the inconsistent findings. This study investigated the gut microbiome communities in...
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Mycobacterium tuberculosis ESAT6 Drives the Activation and Maturation of Bone Marrow-Derived Dendritic Cells via TLR4-Mediated Signaling

Jang AR, Kim G, Hong JJ, Kang SM, Shin SJ, Park JH

6-kDa early secretory antigenic target (ESAT6), a virulent factor of Mycobacterium tuberculosis, is involved in immune regulation. However, the underlying mechanism behind the activation and maturation of dendritic cells (DCs)...
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Deceased donor liver transplantation under the Korean model for end-stage liver disease score-based liver allocation system: 2-year allocation results at a high-volume transplantation center

Ha HS, Hong JJ, Kim IO, Lee SR, Lee AY, Ha TY, Song GW, Jung DH, Park GC, Ahn CS, Moon DB, Kim KH, Lee SG, Hwang S

BACKGROUND: The Korean model for end-stage liver disease (MELD) score-based liver allocation system was started in June 2016 in Korea. METHODS: This study analyzed the detailed allocation results of deceased donor...
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Development of Pre-discharge Group Education Program for Liver Transplant Patients

Yun JS, Lim KC, Jeong JS, Ha HS, Hong JJ, Lee SH, Kim LY, Kim YH, Hwang S

BACKGROUND: This study was conducted to develop a pre-discharge group education program for liver transplant patients, and to contribute to improving the knowledge and performance of self-management after discharge. METHODS: This...
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Gastric gastrointestinal stromal tumor: Does the newly proposed UICC TNM staging system provide better prognostic ability than the National Institutes of Health consensus criteria?

Kim H, Oh SJ, Koo MY, Hong JJ, Koh YT, Choi MG, Sohn TS, Kim KM, Bae JM, Kim S

PURPOSE: The main limitation of the National Institutes of Health (NIH) consensus criteria is the biological and prognostic heterogeneity of tumors while the utility of the newly proposed UICC TNM...
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Kidney Transplantation from the Deceased Donor Who Need Continuous Renal Replace Therapy

Lee JY, Kim YH, Kwon HW, Choi JY, Shin S, Jung JH, Hong JJ, Han DJ

BACKGROUND: Brain death donors may require continuous renal replacement therapy (CRRT) in severe acute renal failure (ARF) during management. To maximize donor organ usage we performed renal transplantation from deceased...
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Experiences of Pregnancy and Childbirth in Women after Liver Transplantation

Ha HS, Lim KC, Hong JJ, Kim IO, Jeon MK, Jeong JS, Lee SH, Son HM, Yi M, Lee SG

  • KMID: 2298226
  • Korean J Adult Nurs.
  • 2013 Dec;25(6):690-700.
PURPOSE: Liver transplantation (LT) is the best treatment for patients with end-stage liver disease and most patients with LT return to their normal life. However, pregnancy and childbirth for women...
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Outcomes of Pancreas Transplantation: Single-Center Experience in Korea

Han DJ, Kim SC, Park JB, Kim YH, Park KT, Hong JJ, Ha HS, Jung JH, Kim IK, Park KC, Min PC

  • KMID: 1966878
  • Korean J Med.
  • 2011 Feb;80(2):167-178.
BACKGROUND/AIMS: Pancreas transplantation (PT) as the ultimate treatment for insulin-dependent diabetes has been the subject of debate clinically. Marked improvements in patient and graft survival, and decreases in postoperative morbidity...
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The Combined Effect of Autologous Fat Injection and Liposculpture for Gluteal Reshaping in Koreans

Kim JH, Hong JJ

  • KMID: 1919859
  • J Korean Soc Plast Reconstr Surg.
  • 2011 Nov;38(6):861-866.
PURPOSE: Together with the breast, buttocks are an important element of attractive body contour. To make a beautiful buttocks, improvement of body contour around the buttock as well as buttock...
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Regulation of Gap Junctional Intercellular Communication in Human Keratinocyte Cells

Kahng HS, Kim BC, Kang SO, Hong JJ, Jun HJ, Choung YH

BACKGROUND AND OBJECTIVES: Unlike the normal skin, cholesteatomas characterized by hyperproliferative keratinocytes exhibits up-regulation of connexins (Cxs) and gap junctional intercellular communication (GJIC). Currently, there are no appropriate clinical methods...
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Chronic Maxillary Sinusitis Occurred after Reconstruction of Inferior Orbital Wall Fracture

Lee JJ, Hong JJ, Kim HJ, Jang SY

A 27-year-old man presented with symptoms of chronic postnasal drip and nasal obstruction, which had begun one year earlier. He had undergone an ophthalmologic operation due to inferior orbital wall...
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Analysis of Maternal and Neonatal Factors Affecting Hematopoietic Parameters of Cord Blood

Lee HR, Roh EY, Yoon JH, Han KS, Kim BJ, Hwang KR, Jeon HW, Hong JJ, Shin S

  • KMID: 1466813
  • Korean J Blood Transfus.
  • 2009 Apr;20(1):1-13.
BACKGROUND: Cord blood (CB) is a useful source of hematopoietic stem cells. In public CB banks, only CB units with good hematopoietic potential are processed and stored because the processing...
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