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Down-regulated Reactive Oxygen Species by Heat Shock Protein 90 in 3-Hydroxykynurenine-induced SKN-SH Cell Death

Kim D, Lee M, Noh Y, Lee D, Lee H, Bach J, Han J, Lee K

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Driving-Related Adverse Events in the Elderly Men: A Population-Based Prospective Cohort Study

Kim JS, Bae JB, Han K, Hong JW, Han JH, Kim TH, Kwak KP, Kim K, Kim BJ, Kim SG, Kim JL, Kim TH, Moon SW, Park JY, Park JH, Byun S, Suh SW, Seo JY, So Y, Ryu SH, Youn JC, Lee KH, Lee DY, Lee DW, Lee SB, Lee JJ, Lee JR, Jeong H, Jeong HG, Jhoo JH, Han JW, Kim KW

Objective This study estimated the incidence of driving-related adverse events and examined the association of cognitive function with the risk of future driving-related adverse events in the elderly Korean male...
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The Antifungal Test: An Efficient Screening Tool for the Discovery of Microbial Metabolites with Respiratory Inhibitory Activity

Han JW, Kim B, Oh M, Choi J, Choi GJ, Kim H

Valuable natural compounds produced by a variety of microorganisms can be used as lead molecules for development of new agrochemicals. Furthermore, high-throughput in vitro screening systems with specific modes of...
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Clinical Perspectives of Parkinson's Disease for Ophthalmologists, Otorhinolaryngologists, Cardiologists, Dentists, Gastroenterologists, Urologists, Physiatrists, and Psychiatrists

Choi JH, Kim JM, Yang HK, Lee HJ, Shin CM, Jeong SJ, Kim WS, Han JW, Yoon IY, Song YS, Bae YJ

Parkinson's disease (PD) is a multisystemic disorder characterized by various non-motor symptoms (NMS) in addition to motor dysfunction. NMS include sleep, ocular, olfactory, throat, cardiovascular, gastrointestinal, genitourinary, or musculoskeletal disorders....
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Effect of Psychological Insulin Resistance, Diabetes Distress, and Diabetes Self-Efficacy on the Insulin Therapy Adherence of Patients with Type 2 Diabetes: An Analysis Based on the Actor-Partner Interdependence Model

Kang JS, Park JH, Han JW

Purpose: This study aimed to identify the effects of psychological insulin resistance, diabetes distress, and diabetes self-efficacy of patients and their spouses on insulin therapy adherence of patients with type...
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Frequency of Depressive Disorders According to Cognitive Continuum in the Elderly Living in the Community

Jo KH, Kwon SO, Han JW, Kim KW, Kwak KP, Kim Bj, Kim SG, Kim JL, Moon SW, Park JH, Youn JC, Lee DY, Lee DW, Lee SB, Lee JJ, Jeong HG, Kim TH, Park JY, Jeong H, Ryu SH, Jhoo JH

  • KMID: 2500619
  • J Korean Geriatr Psychiatry.
  • 2020 Apr;24(1):1-9.
Objective: We investigated the frequency of depressive disorders in the elderly with normal cognition (NC), mild cognitive impairment (MCI) and dementia patients living in the community to find out the...
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Primary Extragonadal Germ Cell Tumors in Klinefelter Syndrome: 10-Years of Experience from a Single Institute

Kim Y, Ahn WK, Han JW, Hahn SM, Kwon SY, Lyu CJ

Background: Approximately 8% of male patients presenting with primary mediastinal germ cell tumors (GCTs) have Klinefelter syndrome (KS), while patients diagnosed with retroperitoneal GCTs also exhibit a range of chromosomal...
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Loss of Heterozygosity at Chromosome 16q Is a Negative Prognostic Factorin Korean Pediatric Patients with Favorable Histology Wilms Tumor:A Report of the Korean Pediatric Hematology Oncology Group (K-PHOG)

Park JE, Noh OK, Lee Y, Choi HS, Han JW, Hahn SM, Lyu CJ, Lee JW, Yoo KH, Koo HH, Jeong SY, Sung KW

Purpose Loss of heterozygosity (LOH) at chromosomes 1p and 16q is a poor prognostic factor in favorable histology Wilms tumor (FHWT). This study investigated the prevalence of LOH at 1p and 16q and...
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Treatment outcome of anaplastic ependymoma under the age of 3 treated by intensity-modulated radiotherapy

Lee J, Chung SY, Han JW, Kim DS, Kim J, Moon JY, Yoon HI, Suh CO

Purpose: Intensity-modulated radiotherapy (IMRT) allows for more precise treatment, reducing unwanted radiation to nearby structures. We investigated the safety and feasibility of IMRT for anaplastic ependymoma patients below 3 years...
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Refinement of intraoral reverse temporalis transfer for facial palsy using a mandibular periosteum flap

Han JW, Sun H

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Can the accurate epidemiological study help to search the etiology of Kawasaki disease?

Han JW

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Clinical Outcomes of Idiopathic Epiretinal Membrane Removal in Patients 80 Years or Older

Han JW, Kim JW, Kim CG, Lee DW, Yoo SJ, Choi MJ, Lew YJ, Kim HS, Cho HJ, Kim JY, Kim JH

PURPOSE: To evaluate clinical outcomes of idiopathic epiretinal membrane removal in patients ≥ 80 years of age. METHODS: A retrospective review of medical records was performed with 56 patients who underwent...
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Clinical Characteristics and Treatment Outcomes in Children, Adolescents, and Young-adults with Hodgkin's Lymphoma: a KPHOG Lymphoma Working-party, Multicenter, Retrospective Study

Lee JM, Choi JY, Hong KT, Kang HJ, Shin HY, Baek HJ, Kim S, Lee JW, Chung NG, Cho B, Cho SG, Park KM, Yang EJ, Lim YT, Suh JK, Kang SH, Kim H, Koh KN, Im HJ, Seo JJ, Cho HW, Ju HY, Lee JW, Yoo KH, Sung KW, Koo HH, Park KD, Hah JO, Kim MK, Han JW, Hahn SM, Lyu CJ, Shim YJ, Kim HS, Do YR, Yoo JW, Lim YJ, Jeon IS, Chueh Hw, Oh SY, Choi HS, Park JE, Lee JA, Park HJ, Park BK, Kim SK, Lim JY, Park ES, Park SK, Choi EJ, Choi YB, Yoon JH, Kook H, the Korean Pediatric Hematology and Oncology Group (KPHOG)

Background: Hodgkin's lymphoma (HL) constitutes 10%–20% of all malignant lymphomas and has a high cure rate (5-year survival, around 90%). Recently, interest has increased concerning preventing secondary complications (secondary cancer,...
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Association of Low Blood Pressure with White Matter Hyperintensities in Elderly Individuals with Controlled Hypertension

Kim JS, Lee S, Suh SW, Bae JB, Han JH, Byun S, Han JW, Kim JH, Kim KW

Background and Purpose Both hypertension and hypotension increase cerebral white matter hyperintensities. However, the effects of hypotension in individuals with treated hypertension are unknown. We analyzed the association of low...
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Low Diastolic Blood Pressure and Cognitive Decline in Korean Elderly People: The Korean Longitudinal Study on Cognitive Aging and Dementia

Lee D, Kim BJ, Han JW, Kim TH, Kwak KP, Kim K, Kim SG, Kim JL, Kim TH, Moon SW, Park JY, Park JH, Byun S, Suh SW, Seo JY, So Y, Ryu SH, Youn JC, Lee KH, Lee DY, Lee DW, Lee SB, Lee JJ, Lee JR, Jeong H, Jeong HG, Jhoo JH, Han K, Hong JW, Bae JB, Kim KW

Objective Cardiovascular diseases are representative risk factors for the onset of cognitive decline. The purpose of this study was to confirm the relationship between diastolic blood pressure and cognitive function...
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Anhedonia and Dysphoria Are Differentially Associated with the Risk of Dementia in the Cognitively Normal Elderly Individuals: A Prospective Cohort Study

Lee JR, Suh SW, Han JW, Byun S, Kwon SJ, Lee KH, Kwak KP, Kim BJ, Kim SG, Kim JL, Kim TH, Ryu SH, Moon SW, Park JH, Lee DW, Youn JC, Lee DY, Lee SB, Lee JJ, Jhoo JH, Kim KW

OBJECTIVE: We investigated the impact of depressed mood (dysphoria) and loss of interest or pleasure (anhedonia)on the risk of dementia in cognitively-normal elderly individuals. METHODS: This study included 2,685 cognitively-normal elderly...
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Normal-But-Low Serum Folate Levels and the Risks for Cognitive Impairment

Jang S, Han JW, Shin J, Kim TH, Kwak KP, Kim K, Kim BJ, Kim SG, Kim JL, Kim TH, Moon SW, Park JY, Park JH, Byun S, Suh SW, Seo J, So Y, Ryu SH, Youn JC, Lee KH, Lee DY, Lee DW, Lee SB, Lee JJ, Lee JR, Jeong H, Jeong HG, Jhoo JH, Han K, Hong JW, Kim KW

OBJECTIVE: This study aimed to examine the association between normal-but-low folate levels and cognitive function in the elderly population using a prospective cohort study. METHODS: We analyzed 3,910 participants whose serum...
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Association of Supplementary Private Health Insurance Type with Unmet Health Care Needs

Han JW, Kim DJ, Min IS, Hahm MI

BACKGROUND: The extent of coverage rate of the public health insurance is still insufficient to meet healthcare needs. Private health insurance (PHI) plays a role to supplement coverage level of...
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Intravascular papillary endothelial hyperplasia (Masson's hemangioma) of the face

Han JW, Lee JH, Kim EK

Intravascular papillary endothelial hyperplasia or Masson's hemangioma is a rare vascular tumor. The reactive proliferation of endothelial cells in this disease mimics other benign or malignant vascular proliferation such as...
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Development of a Screening Algorithm for Alzheimer's Disease Using Categorical Fluency and Confrontational Naming Abilities

Chi YK, Han JW, Park S, Kim TH, Lee JJ, Lee SB, Park JH, Youn JC, Kim JL, Ryu SH, Jhoo JH, Kim KW

OBJECTIVE: Declines in naming ability and semantic memory are well-known features of early Alzheimer's disease (AD). We developed a new screening algorithm for AD using two brief language tests :...
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