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Predictors of Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis

Kim W, Han JM, Lee KE

Background: Most meta-analyses of risk factors for severe or critical outcomes in patients with COVID-19 only included studies conducted in China and this causes difficulties in generalization. Therefore, this study...
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Impact of Exercise on the Presence of Urinary Ketones Based on Korea National Health and Nutrition Examination Survey Data, 2014–2015

Han JM, Joo NS

Background: Ketone bodies are a well-known metabolite from the utilization of fatty acids in the fasting state. Some studies have demonstrated the metabolic benefits of urinary ketones in a specific...
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Protein Phosphatase 1H, Cyclin-Dependent Kinase Inhibitor p27, and Cyclin-Dependent Kinase 2 in Paclitaxel Resistance for Triple Negative Breast Cancers

Hur S, Kim JH, Yun J, Ju YW, Han JM, Heo W, Kim K, Jeong K, Lee HB, Han W, Noh DY, Kim JI, Moon HG

Purpose: Paclitaxel is a cytotoxic chemotherapy commonly used in patients with triple negative breast cancer (TNBC); however, the resistance to paclitaxel is a cause of poor response in the patients....
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Impact of Hospital Volume and the Experience of Endoscopist on Adverse Events Related to Endoscopic Retrograde Cholangiopancreatography: A Prospective Observational Study

Lee HJ, Cho CM, Heo J, Jung MK, Kim TN, Kim KH, Kim Hs, Cho KB, Kim HG, Han Jm, Lee DW, Lee YS

Background/Aims: Few studies have addressed the relationship between the occurrence of adverse events (AEs) in endoscopic retrograde cholangiopancreatography (ERCP) and hospital case volume or endoscopist’s experience with inconsistent results. The...
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Clinical and Laboratory Features of Pediatric Patients with COVID-19: Systematic Review and Meta-analysis

Yoon HY, Cho YA, Yee J, Gwak HS, Han JM

Background: Although the identification of clinical and laboratory features in pediatric COVID-19 patients is essential in establishing an appropriate treatment plan, a systematic review and meta-analysis on the topic has...
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Factors Influencing Imatinib-Induced Hepatotoxicity

Han JM, Yee J, Cho YS, Gwak HS

Purpose Although imatinib-induced hepatotoxicity may aggravate the patient’s clinical condition and alter the treatment plan, the underlying mechanism of and factors influencing imatinibinduced hepatotoxicity have rarely been investigated. The purpose of...
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Comparing Allografts to Autografts for Maintenance of Cervical Sagittal Parameters and Clinical Outcomes Following Anterior Cervical Discectomy and Fusion with Anterior Cervical Plating

Heidt ST, Louie PK, Khan JM, Basques BA, Hirsch B, Varthi A, Paul JC, Goldberg E, An HS

OBJECTIVE: Current literature has not shown if using either allograft or autograft differentially affects postoperative cervical sagittal parameters. The goal of this study was to compare sagittal alignment and patient-reported...
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Differing Associations between Fatty Liver and Dyslipidemia According to the Degree of Hepatic Steatosis in Korea

Han JM, Kim HI, Lee YJ, Lee JW, Kim KM, Bae JC

OBJECTIVE: Fatty liver is associated with insulin resistance-related diseases, such as dyslipidemia, obesity, and type 2 diabetes. The aim of this study was to evaluate the association of dyslipidemia with...
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Pilot Study: An Ocular Biomarker for Diagnosis of Attention Deficit Hyperactivity Disorder

Bae S, Kim JT, Han JM, Han DH

OBJECTIVE: Biomarkers of attention deficit hyperactivity disorder (ADHD) are crucial for early diagnosis and intervention, in which the identification of biomarkers in other areas of the body that represent the...
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Reviews on the Hepatotoxicity of Tyrosine Kinase Inhibitors

Han JM, Gwak HS

BACKGROUND: Small-molecule tyrosine kinase inhibitors (TKIs) have had major impacts on anticancer therapy by targeting the catalytic activities of dysregulated tyrosine kinases. TKIs have not presented traditional toxicities; however, some...
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Prognosis of Differentiated Thyroid Carcinoma with Initial Distant Metastasis: A Multicenter Study in Korea

Kim H, Kim HI, Kim SW, Jung J, Jeon MJ, Kim WG, Kim TY, Kim HK, Kang HC, Han JM, Cho YY, Kim TH, Chung JH

BACKGROUND: Most patients with differentiated thyroid cancer (DTC) have a favorable prognosis. However, patients with DTC and initial distant metastasis have not been commonly found, and their clinical characteristics have...
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Prevalence and Annual Incidence of Thyroid Disease in Korea from 2006 to 2015: A Nationwide Population-Based Cohort Study

Kwon H, Jung JH, Han KD, Park YG, Cho JH, Lee DY, Han JM, Park SE, Rhee EJ, Lee WY

BACKGROUND: The incidence of thyroid nodules has increased worldwide in recent years. Thyroid dysfunction is a potential risk factor for hypercholesterolemia, cardiovascular disease, osteoporosis, arrhythmia, and neuropsychiatric disease. This study...
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Factors That Influence Educational Effectiveness and Learning Satisfaction in Biomedical Research Programs during Premedical School

Yune SJ, Park YS, Cho JH, Han JM, Hwa HM, Lee SY, Im S

Although student research programs have been implemented worldwide, research programs during premedical school have unique characteristics. The purpose of this study is to evaluate factors that influence the effects of...
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Clinical Outcomes of Differentiated Thyroid Cancer Patients with Local Recurrence or Distant Metastasis Detected in Old Age

Han JM, Bae JC, Kim HI, Kwon S, Jeon MJ, Kim WG, Kim TY, Shong YK, Kim WB

BACKGROUND: Differentiated thyroid carcinoma (DTC) shows a very good prognosis, but older patients have a higher recurrence rate and those show poor prognosis than younger patients. The aim of this...
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Diabetes and Endocrine Disease

Bae JC, Han JM

Impaired insulin secretion and insulin resistance are the two main mechanisms leading to type 2 diabetes mellitus. Insulin exerts multiple effects upon target cells, especially skeletal muscle, liver, and adipose...
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Huge pheochromocytoma presented with paraaortic lymph node and spine metastases

Park YW, Moon HJ, Han JS, Han JM, Park JW, Ku YH

Approximately 10–15% of pheochromocytomas are malignant. There are insufficient histologic criteria for the diagnosis of malignant pheochromocytoma. Thus, the term malignant pheochromocytoma is restricted to tumors with local invasion or...
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Intraocular Lens Power Calculation after Refractive Surgery: A Comparative Analysis of Accuracy and Predictability

Kang BS, Han JM, Oh JY, Kim MK, Wee WR

PURPOSE: To compare the accuracy of intraocular lens (IOL) power calculation using conventional regression formulae or the American Society of Cataract and Refractive Surgery (ASCRS) IOL power calculator for previous...
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Serum vitamin D3 levels are not associated with thyroid cancer prevalence in euthyroid subjects without autoimmune thyroid disease

Choi YM, Kim WG, Kim TY, Bae SJ, Kim HK, Jang EK, Jeon MJ, Han JM, Shong YK, Kim WB

BACKGROUND/AIMS: Previous studies have suggested that elevated serum vitamin D levels might protect against thyroid cancer. Elevated serum thyroid stimulating hormone levels and autoimmune thyroid disease (AITD) are suggested to...
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A case of generalized argyria presenting with muscle weakness

Jung I, Joo EJ, Suh BS, Ham CB, Han JM, Kim YG, Yeom JS, Choi JY, Park JH

BACKGROUND: Argyria is a rare irreversible cutaneous pigmentation disorder caused by prolonged exposure to silver. Herein, we report a case of generalized argyria that developed after chronic ingestion of soluble...
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Development of North Korean Version of the Composite International Diagnostic Interview

Lee T, Ahn MH, Jun JY, Han JM, Lee SH, Hahm BJ, Cho MJ, Hong JP

OBJECTIVES: The aim of the study was to develop a North Korean version of the Composite International Diagnostic Interview (NK-CIDI) and to evaluate the reliability and validity of NK-CIDI. METHODS: Subjects...
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