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Efficacy of Buspirone Augmentation of Escitalopram in Patients with Major Depressive Disorder with and without Atypical Features: A Randomized, 8 Week, Multicenter, Open-Label Clinical Trial

Shin C, Ko YH, Shim SH, Kim JS, Na KS, Hahn SW, Lee SH

Objective This study investigated the treatment response and cognitive enhancement effects of buspirone augmentation of escitalopram in patients with major depressive disorder (MDD), according to atypical feature subtypes of MDD. Methods...
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Application of Text-Classification Based Machine Learningin Predicting Psychiatric Diagnosis

Pak D, Hwang M, Lee M, Woo SI, Hahn SW, Lee YJ, Hwang J

ObjectivesZZThe aim was to find effective vectorization and classification models to predict a psychiatric diagnosis from text-based medical records. MethodsZZElectronic medical records (n = 494) of present illness were collected retrospectively in...
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Association Analysis between Chromogranin B Genetic Variations and Smooth Pursuit Eye Movement Abnormality in Korean Patients with Schizophrenia

Park JW, Pak DH, Hwang MG, Lee MJ, Shin HD, Shin TM, Hahn SW, Hwang J, Lee YJ, Woo SI

OBJECTIVES: According to previous studies, the Chromogranin B (CHGB) gene could be an important candidate gene for schizophrenia which is located on chromosome 20p12.3. Some studies have linked the polymorphism...
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Screening for Depressive Disorder in Elderly Patients with Chronic Physical Diseases Using the Patient Health Questionnaire-9

Park SC, Lee HY, Lee DW, Hahn SW, Park SH, Kim YJ, Choi JS, Lee HS, Lee SI, Na KS, Jung SW, Shim SH, Kim KW, Paik JW, Kwon YJ

OBJECTIVE: We aimed to identify depressive symptom profiles that indicated the presence of depressive disorder and present optimal cut-off sub-scores for depressive symptom profiles for detecting depressive disorder in elderly...
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Psychological Characteristics of Elderly Visited to the Department of Psychiatry : Focused on the Cluster Analysis of The Minnesota Multiphasic Personality Inventory-2

Yook S, Baek JM, Hahn SW

OBJECTIVE: This study aimed to analyze psychological characteristics of elderly patients. METHODS: The Minnesota Multiphasic Personality Inventory-2 (MMPI-2) data of 110 elderly patients who visited the department of psychiatry was analyzed....
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Efficacy and Tolerability of Paliperidone Extended-release in the Treatment of First-episode Psychosis: An Eight-week, Open-label, Multicenter Trial

Kang NI, Koo BH, Kim SW, Kim JH, Nam B, Lee BJ, Lee SH, Lee SJ, Lee SH, Jung MH, Hahn SW, Chung YC

OBJECTIVE: We investigated the efficacy and tolerability of paliperidone extended-release (ER) tablets in patients with first-episode psychosis (n=75). METHODS: This was an 8-week, open-label, multicenter trial. The primary outcome variable was...
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No Association between (AAT)n Repeat Polymorphisms in the Cannabinoid Receptor 1 Gene and Smooth Pursuit Eye Movement Abnormality in Korean Patients with Schizophrenia

Kim MJ, Kim CR, Park JW, Pak DH, Shin HD, Choi IG, Hahn SW, Hwang J, Lee YJ, Woo SI

OBJECTIVES: According to previous studies, the cannabinoid receptor 1 (CNR1) gene could be an important candidate gene for schizophrenia. Some studies have linked the (AAT)n trinucleotide repeat polymorphism in CNR1...
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Knowledge and Attitude of 851 Nursing Personnel toward Depression in General Hospitals of Korea

Park SC, Lee HY, Lee DW, Hahn SW, Park SH, Kim YJ, Choi JS, Lee HS, Lee SI, Na KS, Jung SW, Shim SH, Choi J, Paik JW, Kwon YJ

Our study aimed to examine the knowledge and attitude of nursing personnel toward depression in general hospitals of Korea. A total of 851 nursing personnel enrolled at four university-affiliated general...
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Investigation of Knowledge, Attitudes, and Experience Regarding Suicidal Behaviors among Psychiatric Residents in Korea : A Cross-Sectional Study

Lee K, Lee K, Hwang J, Hahn SW, The Committee of Residency Training of the Korean Neuropsychiatric Association

OBJECTIVES: This study investigated the effects of the grade of residents, sociodemographic variables, and clinical experience with suicidal patients on the knowledge and attitudes toward suicide among psychiatric residents in...
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Influence of Depression on Working Memory Measured by Digit Backward Span in the Subjects with Mild Cognitive Impairment and Dementia

Roh YH, Kim MJ, Kim CR, Park JW, Lee YJ, Woo S, Hahn SW, Hwang J

OBJECTIVES: We aimed to explore the influence of depression on working memory in patients with mild cognitive impairment (MCI) and dementia. METHODS: Clinical and neuropsychological data of 43 subjects with mild...
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A Psychoanalytic Approach to Panic Disorder Based on Neurobiology and Classical Conditioning Theory

Kim MJ, Roh YH, Kim CR, Park JW, Lee YJ, Hwang J, Woo SI, Hahn SW

Panic disorder is an important psychiatric problem accompanied by intense anxiety arising from unexpected circumstances and difficult to differentiate from physical disease because of physical symptoms such as shortness of...
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Evidence-Based, Pharmacological Treatment Guideline for Depression in Korea, Revised Edition

Won E, Park SC, Han KM, Sung SH, Lee HY, Paik JW, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Hahn SW, Park YC, Lee MS

This paper aims to introduce, summarize, and emphasize the importance of the 'Evidence-Based, Pharmacological Treatment Guideline for Depression in Korea, Revised Edition'. The guideline broadly covers most aspects of the...
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Does Age at Onset of First Major Depressive Episode Indicate the Subtype of Major Depressive Disorder?: The Clinical Research Center for Depression Study

Park SC, Hahn SW, Hwang TY, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

PURPOSE: The purpose of this study was to evaluate the effects of age at onset of the first major depressive episode on the clinical features of individuals with major depressive...
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Evidence-Based Korean Pharmacological Treatment Guideline for Depression, Revised Edition (III) : Dose Increment, Switching, Combination, and Augmentation Strategy in Antidepressant Therapy

Han KM, Park SC, Won ES, Sung SH, Lee H, Koo JW, Lee K, Lee HY, Paik JW, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Hahn SW, Park YC, Lee MS

  • KMID: 2343634
  • J Korean Neuropsychiatr Assoc.
  • 2013 Sep;52(5):386-401.
OBJECTIVES: The aim of this study was to demonstrate the recommendations for antidepressant treatment strategy of dose increment, switching, combination, and augmentation therapy derived from Evidence-Based Korean Pharmacological Treatment Guideline...
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Evidence-Based Korean Pharmacological Treatment Guideline for Depression, Revised Edition (II) : Antidepressant Efficacy Compared with Placebo, Difference in Efficacy of Antidepressants, and Appropriate Time of Efficacy Judgment in Antidepressant Therapy

Sung SH, Park SC, Han KM, Won ES, Lee HY, Koo JW, Paik JW, Lee KM, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Park YC, Lee MS, Hahn SW

  • KMID: 2343633
  • J Korean Neuropsychiatr Assoc.
  • 2013 Sep;52(5):372-385.
OBJECTIVES: The purpose of this study was to suggest recommendations of antidepressant efficacy compared with placebo, difference in efficacy of antidepressants, and appropriate time of efficacy judgment in antidepressant therapy. METHODS:...
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Evidence-Based Korean Pharmacological Treatment Guideline for Depression, Revised Edition (I) : Initial Choice of Antidepressant Treatment

Park SC, Sung SH, Han KM, Won ES, Lee HY, Paik JW, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Lee H, Hwang TY, Oh KS, Park YC, Lee MS, Hahn SW

  • KMID: 2343589
  • J Korean Neuropsychiatr Assoc.
  • 2013 Jul;52(4):253-262.
OBJECTIVES: The aim of this study is to establish Korean pharmacological treatment guidelines for the initial choice of antidepressant for treatment of moderate or severe depression. METHODS: The process for establishment...
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Development of New Residency Training Programs for Psychiatry in Korea

An K, Lee SH, Park EJ, Sohn I, Lee JH, Lee JS, Hahn SW, the Committee of Residency Training of the Korean Neuropsychiatric Association

  • KMID: 2343582
  • J Korean Neuropsychiatr Assoc.
  • 2013 Jul;52(4):187-196.
As the government has a plan to terminate medical internships and to start the New Resident program, postgraduate medical students should encounter the new residency training program without the internship...
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No Association between Serotonin Receptor 2C-759C/T Polymorphism and Weight Change or Treatment Response to Mirtazapine in Korean Depressive Patients

Lee HY, Oh CK, Ham BJ, Chang HS, Paik JW, Won ES, Hahn SW, Shim SH, Kwon YJ, Jung HY, Lee MS

  • KMID: 2316267
  • Psychiatry Investig.
  • 2013 Jun;10(2):190-195.
OBJECTIVE: Activation of one or more serotonin (5-HT) receptors may play a role in mediating the antidepressant effects of serotonergic antidepressants. The serotonin 2C (5HT 2C) receptor is known to...
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A Comparison of the Clinical Features between Panic Disorder with and without Agoraphobia

Lee HS, Hahn SW, Lim SW, Oh KS

  • KMID: 2299981
  • Korean J Biol Psychiatry.
  • 2007 Aug;14(3):194-200.
OBJECTIVES: This study was performed to investigate the differences of the clinical feature between panic disorder with agoraphobic patients and panic disorder without agoraphobic patients. METHODS: Two hundred nine patients meeting...
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No Association between the 5-HT6 Receptor C267T Polymorphism and Response to Citalopram Treatment in Patient with Major Depressive Disorder

Hahn SW, Lim SW, Oh KS, Kang RH, Lee MS

  • KMID: 2249332
  • Korean J Biol Psychiatry.
  • 2007 Nov;14(4):262-267.
The serotonin 6(5-HT6) receptor gene is a candidate gene for influencing the clinical response to treatment with antidepressants. The purpose of this study was to determine the relationship between the...
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