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Effect of Cyclosporine A-induced Senescence on Cultured Human Corneal Endothelial Cells

Jang YK, Chung TY, Shin YJ

Purpose: To investigate the in vitro effect of cyclosporine A (CsA)-induced senescence on human corneal endothelial cells (HCECs). Methods: HCECs were cultured and incubated with 0-100 µM CsA. Senescence-associated β–galactosidase (SA-β-gal)...
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Efficacy of Topical Cyclosporine Nanoemulsion 0.05% Compared with Topical Cyclosporine Emulsion 0.05% and Diquafosol 3% in Dry Eye

Park CH, Kim MK, Kim EC, Kim JY, Kim TI, Kim HK, Song JS, Yoon KC, Lee DH, Lee HK, Chung TY, Choi CY, Kim HS

PURPOSE: To evaluate the efficacy and safety of cyclosporine nanoemulsion 0.05% compared to cyclosporine emulsion 0.05% and diquafosol sodium 3%. METHODS: This was a multicenter, randomized, evaluator-masked, active control, parallel, phase...
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Comparison of Posterior Capsule Rupture Rate during Phacoemulsification by Novice Ophthalmologists: Microscope vs. Intracameral Illumination

Kim YJ, Seo H, Lee JH, Kim SW, Chung TY, Lee SJ, Park KH, Nam DH

PURPOSE: We compared the posterior capsule rupture (PCR) rate between microscope versus intracameral illumination in phacoemulsification surgery performed by novice ophthalmologists. METHODS: We conducted a retrospective chart review of 300 eyes...
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Distribution and Characteristics of Meibomian Gland Dysfunction Subtypes: A Multicenter Study in South Korea

Eom Y, Na KS, Cho KJ, Hwang HS, Kim SW, Chung TY, Jun RM, Song JS, Kim HS, Korea Meibomian Gland & Ocular Surface Study Group

PURPOSE: We sought to evaluate the distribution and characteristics of meibomian gland dysfunction (MGD) and the treatment patterns for symptomatic MGD patients in South Korea. METHODS: One hundred ninety-six right eyes...
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Bilateral Cataract after Taking Oxcarbazepine

Kim HJ, Jung NY, Yang CM, Chung TY, Lim DH

PURPOSE: To report a case of bilateral posterior subcapsular cataract after taking oxcarbazepine (Trileptal®, Novartis, Basel, Swiss). CASE SUMMARY: A 19-year-old female visited our clinic with decreased vision in both eyes....
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A Case of Corneal Dysplasia with Identification of POLH Gene Variants in Xeroderma Pigmentosum

Shin EH, Lim DH, Kim YD, Woo KI, Han J, Park JE, Chung TY, Ki CS

PURPOSE: To discuss the clinical course and diagnosis of corneal dysplasia in a xeroderma pigmentosum patient based on a genetic evaluation. CASE SUMMARY: A 42-year-old female visited our clinic for decreased...
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Comparison of Efficacy and Sensation of Instillation between 0.05% Cyclosporine Nanoemulsion and Microemulsion Type

Shin EH, Lim DH, Yang CM, Chung TY

PURPOSE: To evaluate and compare the efficacy and sensation of instillation between 0.05% cyclosporine nanoemulsion group and microemulsion group. METHODS: This is a double-blind, prospective randomized clinical trial. Patients had 2...
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Ocular Manifestations, Treatment Outcome and Clinical Course of Infective Keratitis of Keratitis-Ichthyosis-Deafness Syndrome

Son KY, Paik DW, Cho EH, Shin D, Woo HI, Chung TY, Lim DH

PURPOSE: To report the ocular manifestations and treatment outcomes of infective keratitis in a patient with keratitis-ichthyosis-deafness (KID) syndrome and to report a newly discovered mutation in the GJB2 gene...
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Diagnostic Utility of Polymerase Chain Reaction for Acanthamoeba in Contact Lens-related Keratitis with Epithelial Defects

Kang MC, Lim DH, Huh HJ, Yoo IY, Chung TY

PURPOSE: To report contact lens related Acanthamoeba keratitis with corneal epithelial defect cases which were diagnosed using polymerase chain reaction (PCR). CASE SUMMARY: A 51-year-old male visited our hospital for loss...
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Clinical outcomes of currently available multifocal intraocular lenses

Chung TY

This study investigates the characteristics and clinical outcomes of different types of extended depth-of-focus and multifocal intraocular lenses (IOLs) to determine which IOL can increase patient satisfaction. Modern cataract surgery...
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Xenotransplantation of Cultured Human Corneal Endothelial Cell Sheets

Lee YP, Chung TY, Hyon JY, Shin YJ

PURPOSE: To investigate the possibility of transplantation into rabbits of collagenase-induced cultured human corneal endothelial cell plate-rabbit corneal stromal complexes. METHODS: Human corneal endothelial cells were isolated from residual corneal limbus...
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Short-term Clinical Outcomes of Femtosecond Laser-assisted Cataract Surgery: Comparison with Conventional Phacoemulsification

Choi JH, Yang CM, Chung NY, Lim DH, Chung TY

PURPOSE: To evaluate the short-term clinical outcome of femtosecond laser-assisted cataract surgery at the initial phase and to compare it with results from conventional phacoemulsification. METHODS: This retrospective study was performed...
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Lamina Cribrosa Changes after Laser In Situ Keratomileusis in Myopic Eyes

Lee S, Choi DY, Lim DH, Chung TY, Han JC, Kee C

PURPOSE: To determine deep optic nerve head structure changes after transient intraocular pressure elevation during laser in situ keratomileusis (LASIK) for myopia. METHODS: Enhanced depth imaging-optical coherence tomography was performed in...
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Myopic Shift after Implantation of a Novel Diffractive Trifocal Intraocular Lens in Korean Eyes

Hwang S, Lim DH, Hyun J, Kim MJ, Chung TY

PURPOSE: To evaluate the clinical outcomes of cataract surgery using novel diffractive trifocal intraocular lenses (IOLs) in Koreans. METHODS: This was a retrospective, consecutive, interventional study of cataract surgery using POD...
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Comparison of Intraocular Lens Power Calculation Methods Following Myopic Laser Refractive Surgery: New Options Using a Rotating Scheimpflug Camera

Cho K, Lim DH, Yang CM, Chung ES, Chung TY

PURPOSE: To evaluate and compare published methods of calculating intraocular lens (IOL) power following myopic laser refractive surgery. METHODS: We performed a retrospective review of the medical records of 69 patients...
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The Incidence and Risk Factors of Lens-iris Diaphragm Retropulsion Syndrome during Phacoemulsification

Lim DH, Shin DH, Han G, Chung ES, Chung TY

PURPOSE: In the present study, the incidence and risk factors of lens-iris diaphragm retropulsion syndrome (LIDRS) were evaluated. METHODS: Patients who underwent cataract surgery using phacoemulsification between June 2014 and December...
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Prevalence and Risk Factors of Dry Eye Disease after Refractive Surgery

Son DY, Hwang S, Hyun J, Lim DH, Chung ES, Chung TY

PURPOSE: To assess the prevalence and the risk factors of dry eye disease after refractive surgery. METHODS: A retrospective study was performed on 180 eyes of 98 patients based on medical...
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Effects and Prognostic Factors of Automated Thermodynamic System Treatment for Meibomian Gland Dysfunction

Nam SW, Lim DH, Hyun J, Chung TY

PURPOSE: To evaluate the effect and prognostic factors of automated thermodynamic treatment (thermal compression therapy device [KCL 1100®]) for Meibomian gland dysfunction (MGD). METHODS: Patients (48 eyes of 24 subjects) with...
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Effects of Continuous Curvilinear Capsulorhexis, Intraocular Lens Decentration and Tilt on Clinical Outcomes

Eo DR, Lim DH, Hyun J, Lee JY, Lim HW, Oh JE, Chung ES, Chung TY

PURPOSE: To evaluate the effects of continuous curvilinear capsulorhexis, intraocular lens (IOL) decentration and tilt on postoperative clinical outcomes after cataract surgery. METHODS: We reviewed 62 eyes of 52 patients who...
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Second-Eye Refractive Error Depending on the Reflection Rate of First-Eye Refractive Error in Cataract Surgeries

Eo DR, Lim DH, Hyun J, Choi JH, Lee MG, Chung ES, Chung TY

PURPOSE: To evaluate the reflection rate of the first eye in order to minimize the real refractive error in the second eye in bilateral consecutive cataract surgeries. METHODS: A retrospective analysis...
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