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Effect of Cyclosporine A-induced Senescence on Cultured Human Corneal Endothelial Cells

Jang YK, Chung TY, Shin YJ

Purpose: To investigate the in vitro effect of cyclosporine A (CsA)-induced senescence on human corneal endothelial cells (HCECs). Methods: HCECs were cultured and incubated with 0-100 µM CsA. Senescence-associated β–galactosidase (SA-β-gal)...
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Immunoglobulin G4-Related Disease of the Ovary Mimicking Bilateral Ovarian Malignancies

Sim Y, Chung T, Jung DC, Kim HS, Oh YT

Immunoglobulin G4-related disease (IgG4-RD) is a fibro-inflammatory condition characterized by several pathological features that can theoretically involve all organs. Ovarian involvement in IgG4-RD has been reported by two studies only....
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Effect of Weight Changes on the Development of Erosive Esophagitis

Chung TH, Lee J, Jeong ID, Lee KC

Background: Gastroesophageal reflux disease is highly prevalent among overweight and obese individuals. This study aimed to investigate the effect of weight change on the development of erosive esophagitis (EE). Methods: A...
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Efficacy of Topical Cyclosporine Nanoemulsion 0.05% Compared with Topical Cyclosporine Emulsion 0.05% and Diquafosol 3% in Dry Eye

Park CH, Kim MK, Kim EC, Kim JY, Kim TI, Kim HK, Song JS, Yoon KC, Lee DH, Lee HK, Chung TY, Choi CY, Kim HS

PURPOSE: To evaluate the efficacy and safety of cyclosporine nanoemulsion 0.05% compared to cyclosporine emulsion 0.05% and diquafosol sodium 3%. METHODS: This was a multicenter, randomized, evaluator-masked, active control, parallel, phase...
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Korean Alcohol Guidelines for Moderate Drinking Based on Facial Flushing

Lee S, Kim JS, Jung JG, Oh MK, Chung TH, Kim J

This study investigated advantages and potential risks associated with drinking alcohol in Koreans based on the alcohol flush reaction. Our investigation reviewed published studies and examined moderate-drinking levels for Koreans...
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Comparison of Posterior Capsule Rupture Rate during Phacoemulsification by Novice Ophthalmologists: Microscope vs. Intracameral Illumination

Kim YJ, Seo H, Lee JH, Kim SW, Chung TY, Lee SJ, Park KH, Nam DH

PURPOSE: We compared the posterior capsule rupture (PCR) rate between microscope versus intracameral illumination in phacoemulsification surgery performed by novice ophthalmologists. METHODS: We conducted a retrospective chart review of 300 eyes...
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Distribution and Characteristics of Meibomian Gland Dysfunction Subtypes: A Multicenter Study in South Korea

Eom Y, Na KS, Cho KJ, Hwang HS, Kim SW, Chung TY, Jun RM, Song JS, Kim HS, Korea Meibomian Gland & Ocular Surface Study Group

PURPOSE: We sought to evaluate the distribution and characteristics of meibomian gland dysfunction (MGD) and the treatment patterns for symptomatic MGD patients in South Korea. METHODS: One hundred ninety-six right eyes...
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Bilateral Cataract after Taking Oxcarbazepine

Kim HJ, Jung NY, Yang CM, Chung TY, Lim DH

PURPOSE: To report a case of bilateral posterior subcapsular cataract after taking oxcarbazepine (Trileptal®, Novartis, Basel, Swiss). CASE SUMMARY: A 19-year-old female visited our clinic with decreased vision in both eyes....
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A Case of Corneal Dysplasia with Identification of POLH Gene Variants in Xeroderma Pigmentosum

Shin EH, Lim DH, Kim YD, Woo KI, Han J, Park JE, Chung TY, Ki CS

PURPOSE: To discuss the clinical course and diagnosis of corneal dysplasia in a xeroderma pigmentosum patient based on a genetic evaluation. CASE SUMMARY: A 42-year-old female visited our clinic for decreased...
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Comparison of Efficacy and Sensation of Instillation between 0.05% Cyclosporine Nanoemulsion and Microemulsion Type

Shin EH, Lim DH, Yang CM, Chung TY

PURPOSE: To evaluate and compare the efficacy and sensation of instillation between 0.05% cyclosporine nanoemulsion group and microemulsion group. METHODS: This is a double-blind, prospective randomized clinical trial. Patients had 2...
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Ocular Manifestations, Treatment Outcome and Clinical Course of Infective Keratitis of Keratitis-Ichthyosis-Deafness Syndrome

Son KY, Paik DW, Cho EH, Shin D, Woo HI, Chung TY, Lim DH

PURPOSE: To report the ocular manifestations and treatment outcomes of infective keratitis in a patient with keratitis-ichthyosis-deafness (KID) syndrome and to report a newly discovered mutation in the GJB2 gene...
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Diagnostic Utility of Polymerase Chain Reaction for Acanthamoeba in Contact Lens-related Keratitis with Epithelial Defects

Kang MC, Lim DH, Huh HJ, Yoo IY, Chung TY

PURPOSE: To report contact lens related Acanthamoeba keratitis with corneal epithelial defect cases which were diagnosed using polymerase chain reaction (PCR). CASE SUMMARY: A 51-year-old male visited our hospital for loss...
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Clinical outcomes of currently available multifocal intraocular lenses

Chung TY

This study investigates the characteristics and clinical outcomes of different types of extended depth-of-focus and multifocal intraocular lenses (IOLs) to determine which IOL can increase patient satisfaction. Modern cataract surgery...
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Increased Expression of the Matrix-Modifying Enzyme Lysyl Oxidase-Like 2 in Aggressive Hepatocellular Carcinoma with Poor Prognosis

Choi J, Chung T, Rhee H, Kim YJ, Jeon Y, Yoo JE, Noh S, Han DH, Park YN

BACKGROUND/AIMS: Lysyl oxidase-like 2 (LOXL2), a collagen-modifying enzyme, has been implicated in cancer invasiveness and metastasis. METHODS: We evaluated the expression of LOXL2 protein, in addition to carbonic anhydrase IX (CAIX),...
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Recurrent Indeterminate Dendritic Cell Tumor of the Skin

Joo JW, Chung T, Cho YA, Kim SK

Indeterminate dendritic cell tumor (IDCT) is a dendritic cell tumor that displays histologic features similar to those of Langerhans cells. The origin of the indeterminate cells may represent precursors of...
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Xenotransplantation of Cultured Human Corneal Endothelial Cell Sheets

Lee YP, Chung TY, Hyon JY, Shin YJ

PURPOSE: To investigate the possibility of transplantation into rabbits of collagenase-induced cultured human corneal endothelial cell plate-rabbit corneal stromal complexes. METHODS: Human corneal endothelial cells were isolated from residual corneal limbus...
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Short-term Clinical Outcomes of Femtosecond Laser-assisted Cataract Surgery: Comparison with Conventional Phacoemulsification

Choi JH, Yang CM, Chung NY, Lim DH, Chung TY

PURPOSE: To evaluate the short-term clinical outcome of femtosecond laser-assisted cataract surgery at the initial phase and to compare it with results from conventional phacoemulsification. METHODS: This retrospective study was performed...
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Lamina Cribrosa Changes after Laser In Situ Keratomileusis in Myopic Eyes

Lee S, Choi DY, Lim DH, Chung TY, Han JC, Kee C

PURPOSE: To determine deep optic nerve head structure changes after transient intraocular pressure elevation during laser in situ keratomileusis (LASIK) for myopia. METHODS: Enhanced depth imaging-optical coherence tomography was performed in...
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Pediatric Deaths and Venipuncture

Chung T, Park S, Kim HJ, Yang K, Ha H

Venipuncture is a routine and relatively safe and painless medical procedure, necessary for accurate diagnosis and treatment. However, given that pain related to medical procedures may have adverse effects for...
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Myopic Shift after Implantation of a Novel Diffractive Trifocal Intraocular Lens in Korean Eyes

Hwang S, Lim DH, Hyun J, Kim MJ, Chung TY

PURPOSE: To evaluate the clinical outcomes of cataract surgery using novel diffractive trifocal intraocular lenses (IOLs) in Koreans. METHODS: This was a retrospective, consecutive, interventional study of cataract surgery using POD...
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