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Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients

Bae H, Na DH, Chang JY, Park KH, Min JW, Ko EJ, Lee H, Yang CW, Chung BH, Oh EJ

Background/Aims To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods We...
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Relationship between diet quality and sarcopenia in elderly Koreans: 2008–2011 Korea National Health and Nutrition Examination Survey

Na W, Kim J, Chung BH, Jang DJ, Sohn C

BACKGROUND/OBJECTIVES: Given the increasing proportion of the Korean population that is aged 65 years and older, the present study analyzed the relationship between diet quality and sarcopenia in elderly persons...
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Optimal PSA Threshold for Androgen-Deprivation Therapy in Patients with Prostate Cancer following Radical Prostatectomy and Adjuvant Radiation Therapy

Ahn HK, Lee KS, Kim D, Rha KH, Hong SJ, Chung BH, Koo KC

Purpose: The benefits of early administration of androgen-deprivation therapy (ADT) in patients with prostate-specific antigen (PSA)-only recurrent prostate cancer (PCa) following radical prostatectomy (RP) are controversial. We investigated the impact...
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The differential effects of anemia on mortality in young and elderly end-stage renal disease patients

Ko EJ, Kim YK, Cho JH, Kim YS, Kang SW, Kim NH, Kim YL, Yang CW, Chung BH

Background: The aim of this study was to compare the effect of anemia on clinical outcomes according to age in patients with end-stage renal disease (ESRD). Methods: A total of 3,409...
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Recurrent Severe Hyponatremia in a Patient with Sjögren’s Syndrome

Kim HD, Lee J, Chung BH, Yang CW, Kim YS, Park CW

Sjögren's syndrome (SS) is an autoimmune disease that presents with exocrine gland dysfunction. Renal involvement is common in SS and often results in tubulointerstitial nephritis, renal tubular acidosis, and Fanconi’s...
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Development of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of Literature

Lee S, Lee HY, Park Y, Ko EJ, Ban TH, Chung BH, Lee HS, Yang CW

Chaga mushrooms are widely used in folk remedies and in alternative medicine. Contrary to many beneficial effects, its adverse effect is rarely reported. We here report a case of end-stage...
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Amyloid light-chain amyloidosis presented as focal segmental glomerulosclerosis in a kidney transplant recipient

Park SH, Kwon SH, Lee HY, Lee S, Ko EJ, Ban TH, Chung BH, Choi YJ, Yang CW

Amyloid light-chain (AL) amyloidosis after kidney transplantation is a rare disease in the world, and only one case of systemic AL amyloidosis after kidney transplantation is reported in Korea. We...
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Assessment of nephrotoxicity of herbal medicine containing aristolochic acid in mice

Quan Y, Jin L, Luo K, Jin J, Lim SW, Shin YJ, Ko EJ, Chung BH, Yang CW

Background/Aims: It is undetermined if herbal medicines (HM) containing aristolochic acid (AA)-containing have similar nephrotoxicity to AA itself. Methods: We administered HM containing a high concentration of AA for 5 days...
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Acute allograft dysfunction mimicking thrombotic microangiopathy in kidney transplant recipient with renal infarction: case report and review of literatures

Lee S, Ho LY, Chung BH, Park SC, Yang CW

Acute allograft dysfunction is rarely observed in kidney transplantation (KT). We report an unusual case of acute allograft dysfunction mimicking thrombotic microangiopa- thy (TMA) in recipient with renal infarction. A 65-year-old man...
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Differential impact of allograft rejection on kidney transplant patients with BK virus infection

Min JW, Park JB, Park JH, Park JW, Yang J, Ahn C, Yang CW, Chung BH

Background: BK virus-associated nephropathy (BKVAN) is a known risk factor for allograft dysfunction and graft failure in kidney transplant recipients. The mainstay of treatment for BKVAN is reduction of immunosuppression...
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Usefulness of pre- and post-transplant BK virus-specific ELISPOT assay for predicting the outcome of BK virus infection in kidney transplant recipients

Ko EJ, Bae H, Park KH, Yang CW, Chung BH, Oh EJ

Background: To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay at pre- and post-transplant can predict the outcome of BKV infection in kidney...
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The clinical utility of preformed C1q-binding donor-specific anti-HLA antibodies in kidney transplantation

Lee S, Yang CW, Chung BH

Background: The role of C1q-binding donor-specific antibody (DSA) in antibody-mediated rejection (AMR) is considered important. De novo C1q-binding DSA is well known as an associated factor for increased risk of...
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The clinical impact of preformed human leukocyte antigen-DQ donor-specific antibodies on graft outcomes in kidney transplantation

Lee S, Chung BH, Yang CW

Background: De-novo human leukocyte antigen (HLA)-DQ donor-specific antibody (DSA) is well known as a risk factor for graft dysfunction and graft loss in kidney transplantation (KT). Recently, the influence of...
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Changes of T lymphocyte subsets after kidney transplantation according to induction immunosuppressants

Kim HD, Bae H, Yang CW, Oh EJ, Chung BH

Background: The aim of this study is to investigate the change of T cell subsets during early post-transplant period according to the type of induction therapy (anti-thymocyte globulin [ATG] vs....
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Human leukocyte antigen-DR/DQ eplet mismatch analysis for primary alloimmune risk stratification of non-sensitized kidney transplant recipients

Lee H, Min JW, Kang H, Yang CW, Chung BH, Oh EJ

Background: Human leukocyte antigen (HLA) analysis has been suggested as a predictive tool for alloimmune risk stratification in kidney transplantation (KT). We investigated whether the whole or single molecule HLA...
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Combined impact of pre-sensitization and delayed graft function on the development of allograft rejection in deceased donor kidney transplantation: nationwide cohort study

Lee H, Park Y, Ban TH, Song SH, Song SH, Yang J, Ahn C, Yang CW, Chung BH

Background: Both pre-sensitization to human leukocyte antigen and delayed graft function (DGF) is well documented to be associated with poor allograft outcome. The aim of this study is to investigate...
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Impact of kidney and recipient weight incompatibility on the allograft outcomes in kidney transplant recipients with pre-transplant diabetes mellitus: a single center retrospective cohort study

Park Y, Lee H, Ko J, Yang CW, Chung BH

Background: The aim of this study was to analyze the impact on the adverse allograft outcome of transplanting relatively small kidneys in patients with pre-transplant diabetes mellitus (DM). Methods: From January...
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Strategy to avoid open surgical conversion after endovascular aortic aneurysm repair for patients with infrarenal abdominal aortic aneurysm

Chung BH, Heo SH, Park YJ, Kim DI, Kim DK, Kim YW

Purpose: Open surgical conversion (OSC) is the last treatment option for patients with endovascular aneurysm repair (EVAR) failure. We investigated the underlying causes of EVAR failure requiring OSC and attempted...
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Comparison of prostate cancer detection rates of various prostate biopsy methods for patients with prostate-specific antigen levels of < 10.0 ng/mL in real-world practice

Oh KT, Koo KC, Chung BH, Lee KS

PURPOSE: Several strategies of prostate biopsy (PBx) have been introduced to improve prostate cancer (PCa) detection rates. However, studies comparing cancer detection rates (CDRs) according to biopsy methods in real-world...
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Enzalutamide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer: A retrospective Korean multicenter study in a real-world setting

Jung SI, Kim MS, Jeong CW, Kwak C, Hong SK, Kang SH, Joung JY, Lee SH, Yun SJ, Kim TH, Park SW, Jeon SS, Kang M, Lee JY, Chung BH, Hong JH, Ahn H, Kim CS, Kwon DD

PURPOSE: This study aimed to evaluate the clinical efficacy of enzalutamide in chemotherapy-naïve metastatic castration-resistant prostate cancer (mCRPC) patients using real-world data from Korean patients. MATERIALS AND METHODS: We retrospectively reviewed...
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