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A Risk Prediction Model for Operative Mortality after Heart Valve Surgery in a Korean Cohort

Kim HJ, Kim JB, Kim SO, Yun SC, Lee S, Lim C, Choi JW, Hwang HY, Kim KH, Lee SH, Yoo JS, Sung K, Je HG, Hong SC, Kim YJ, Kim SH, Chang BC

Background: This study aimed to develop a new risk prediction model for operative mortality in a Korean cohort undergoing heart valve surgery using the Korea Heart Valve Surgery Registry (KHVSR)...
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Dental treatment under general anesthesia for patients with severe disabilities

Choi J, Doh RM

Patients with disabilities have difficulties tolerating in-office dental treatment due to limitations relating to cooperation and/or physical problems. Therefore, they often require general anesthesia or sedation to facilitate safe treatment....
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Acute Acquired Concomitant Esotropia in Anti-GQ1b-Antibody Syndrome

Kwon E, Yoon BA, Kim HJ, Choi JY, Yang HK, Kim JS

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Health-related Quality of Life Outcomes of Adalimumab for Patients With Rheumatoid Arthritis in Korea

Lee Ms, Lee CH, Lee HS, Sung YK, Choi JR, Park K, Lim MK, Choi BY, Kim HA, Choi SW, Lee Y, Yoo WH

Objective: Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disorder that impairs patients’ overall health-related quality of life (HRQOL). In this study, we evaluated the effect of adalimumab in Korean...
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Hyaluronic Acid Coating on Hydrophobic Tracheal Scaffold Enhances Mesenchymal Stem Cell Adhesion and Tracheal Regeneration

Choi JS, Lee MS, Kim J, Eom MR, Jeong EJ, Lee M, Park SA, Jeong JH, Kwon SK

BACKGROUND: Long segmental tracheal repair is challenging in regenerative medicine due to low adhesion of stem cells to tracheal scaffolds. Optimal transplantation of stem cells for tracheal defects has not...
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Evaluation of Left Atrial Appendage Isolation Using Cardiac MRI after Catheter Ablation of Atrial Fibrillation: Paradox of Appendage Reservoir

Cho H, Cho Y, Shim J, Choi Ji, Kim YH, Oh YW, Hwang SH

Objective: To assess the effect of left atrial appendage (LAA) isolation on LAA emptying and left atrial (LA) function using cardiac MRI in patients who underwent successful catheter ablation of...
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Anti-inflammatory, Anti-glycation, Anti-tyrosinase and CDK4 Inhibitory Activities of Alaternin (=7-Hydroxyemodin)

Bhatarrai G, Choi JW, Seong SH, Nam TJ, Jung HA, Choi JS

The aim of this study was to anatomize the therapeutic potential of alaternin (=7-hydroxyemodin) against inflammation, advanced glycation end products (AGEs) formation, tyrosinase, and two cyclin-dependent kinases (CDKs), CDK2 and...
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Study on the characterization, biocompatibility and efficacy of sponge brush products for oral care

Yang SY, Choi JW, Oh SH

A sponge brush is an oral hygiene product that is used to clean buccal, gingival and palatal mucosa. The aim of this study was to observe the appearance, porosity, water...
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Pancreatic Paraganglioma: a Case Report and Literature Review

Park JS, Min SJ, Min SK, Choi JA

Paraganglioma is a rare tumor of paraganglia, derived from neural crest cells in sympathetic or parasympathetic ganglions. It can be widely distributed from the skull base to the bottom of...
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Factors Associated with Postoperative Recovery among Lung Cancer Patients with Walking Exercise after Lung Resection

Kim Y, Choi J, Cho JH, Choi M

Background: Treatment for lung cancer, which has high incidence and mortality rates, involves lung resection; however, the risk of postoperative pulmonary complications is high. Early walking exercise is a core...
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Effect of Transport Time on the Use of Reperfusion Therapy for Patients with Acute Ischemic Stroke in Korea

Choi JC, Kim JG, Kang CH, Bae HJ, Kang J, Lee SJ, Park JM, Park TH, Cho YJ, Lee KB, Lee J, Kim DE, Cha JK, Kim JT, Lee BC, Lee JS, Kim AS

Background: We investigated the association between geographic proximity to hospitals and the administration rate of reperfusion therapy for acute ischemic stroke. Methods: We identified patients with acute ischemic stroke who visited...
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Association between Early Spermarche and Suicide Attempts in Boys: the Korea Youth Risk Behavior Web-based Survey

Lee YJ, Ahn IY, Kim BJ, Lee CS, Cha B, Lee SJ, Seo J, Choi JW, Lee YJ, Lim E, Lee D

Background: Puberty is a biologically and psychologically unstable period, and pubertal changes differ by sex. However, most previous studies on pubertal timing and suicide have focused on girls. This study...
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Single-nucleotide polymorphismbased epidemiological analysis of Korean Mycobacterium bovis isolates

Kim TW, Jang YH, Jeong MK, Seo Y, Park CH, Kang S, Lee YJ, Choi JS, Yoon SS, Kim JM

Background: Bovine tuberculosis (TB) is caused by Mycobacterium bovis, a well-known cause of zoonotic tuberculosis in cattle and deer, and has been investigated in many physiological and molecular studies. However,...
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Influenza Vaccine Effectiveness in Children at the Emergency Department during the 2018-2019 Season: the First Season School-aged Children Were Included in the Korean Influenza National Immunization Program

Yoon Y, Choi Js, Park M, Cho H, Park M, Huh HJ, Kim YJ, Son MH

Background: For the 2018–2019 season, the national influenza immunization program expanded to cover children aged from 6 months to 12 years in Korea. This study aimed to analyze vaccine effectiveness...
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Far-infrared rays enhance mitochondrial biogenesis and GLUT3 expression under low glucose conditions in rat skeletal muscle cells

Seo Y, Kim YW, Lee D, Kim D, Kim K, Kim T, Baek C, Lee Y, Lee J, Lee H, Jang G, Jeong W, Choi J, Hwang D, Suh JS, Kim SW, Kim HK, Han J, Bang H, Kim JH, Zhou T, Ko JH

Far-infrared rays (FIR) are known to have various effects on atoms and molecular structures within cells owing to their radiation and vibration frequencies. The present study examined the effects of...
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Protection of palmitic acid treatment in RAW264.7 cells and BALB/c mice during Brucella abortus 544 infection

Bernardo Reyes AW, Ngoc Huy TX, Vu SH, Kim HJ, Lee JJ, Choi JS, Lee JH, Kim S

Background: We previously elucidated the protective mechanism of Korean red ginseng oil (RGO) against Brucella abortus infection, and our phytochemical analysis revealed that palmitic acid (PA) was an abundant...
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Key Principles of Clinical Validation, Device Approval, and Insurance Coverage Decisions of Artificial Intelligence

Park SH, Choi J, Byeon JS

Artificial intelligence (AI) will likely affect various fields of medicine. This article aims to explain the fundamental principles of clinical validation, device approval, and insurance coverage decisions of AI algorithms...
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Early and Two-year Outcomes after Sutureless and Conventional Aortic Valve Replacement: a Nationwide Population-based Study

Choi JW, Kim HJ, Kim JB, Lee S, Lim C, Chang BC, Suh Y, Lee NR, Hwang HY

Background: We compared early and 2-year clinical outcomes of sutureless aortic valve replacement (SAVR) with conventional aortic valve replacement (CAVR) in a nationwide study based on claims data. Methods: From December...
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Genomic mutation profiling using liquid biopsy in Korean patients with prostate cancer: Circulating tumor DNA mutation predicts the development of castration resistance

Yu J, Cho E, Choi J, Lim JE, Lee J, Kang M, Sung HH, Jeong BC, Seo SI, Jeon SS, Lee HM, Jeon HG

Purpose: To investigate germline and somatic mutation profiles in Korean patients with prostate cancer using liquid biopsy and solid tissue testing and to evaluate the prognostic value of circulating tumor...
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Sodium/glucose Co-Transporter 2 Inhibitor, Empagliflozin, Alleviated Transient Expression of SGLT2 after Myocardial Infarction

Lee SY, Lee TW, Park GT, Kim JH, Lee HC, Han JH, Yoon A, Yoon D, Kim S, Jung SM, Choi JH, Chon MK, Lee SH, Hwang KW, Kim J, Park YH, Kim JH, Chun KJ, Hur J

Background and Objectives: Large clinical studies of sodium/glucose cotransporter 2 (SGLT2) inhibitors have shown a significant beneficial effect on heart failure-associated hospitalization and cardiovascular events. As SGLT2 is known to...
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