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A case of 45,X/47,XXX mosaic Turner syndrome: Clinical manifestations and effect of growth hormone treatment

Yoo SH, Ahn MB, Kim SH, Cho WK, Jung MH, Suh BK, Cho K

In Turner syndrome (TS), 45,X/47,XXX mosaicism is a rare genotype. Due to its low frequency, the clinical features and prognosis are not clearly known. A 10-year-old girl was diagnosed with...
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Combined Periciliary Y-V Epicanthoplasty and Modified Hotz Procedure in Patients with Down Syndrome

Park SK, Cho WK, Lee NY

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Predicting First-Year Growth in Response to Growth Hormone Treatment in Prepubertal Korean Children with Idiopathic Growth Hormone Deficiency: Analysis of Data from the LG Growth Study Database

Cho WK, Ahn MB, Kim EY, Cho KS, Jung MH, Suh BK

Background: The first-year growth in response to growth hormone (GH) treatment seems to be the most important factor in determining the overall success of GH treatment. Methods: Data from children (n...
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Carcinoembryonic Antigen Improves the Performance of MagneticResonance Imaging in the Prediction of Pathologic Response afterNeoadjuvant Chemoradiation for Patients with Rectal Cancer

Yoo GS, Park HC, Yu JI, Choi DH, Cho WK, Park YS, Park JO, Lim HY, Kang WK, Lee WY, Kim HC, Yun SH, Cho YB, Park YA, Song KD, Kim SH, Ha SY

Purpose The purpose of this study was to investigate the role of carcinoembryonic antigen (CEA) levels in improving the performance of magnetic resonance imaging (MRI) for the prediction of pathologic response after the...
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Acer tegmentosum Maxim Prevents Bone Loss by Inhibiting Osteoclastogenesis and Promoting Osteoblast Mineralization in Ovariectomized Mice

Oh TW, Park KI, Do HJ, Kim K, Yang HJ, Cho WK, Ma JY

Osteoporosis is a worldwide disease leading to significant economic and societal burdens globally. Osteoporosis is caused by unbalanced bone remodeling between the rate of osteoclast bone resorption and osteoblast bone...
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Clinical Outcomes of Postoperative Radiotherapy Following Radical Prostatectomy in Patients with Localized Prostate Cancer: A Multicenter Retrospective Study (KROG 18-01) of a Korean Population

Lee SU, Cho KH, Park W, Cho WK, Kim JS, Wee CW, Kim YS, Kim JH, Nam TK, Cho J, Jeong SM, Kim Y, Shim SJ, Choi Y, Kim JS

Purpose The purpose of this study was to investigate the clinical outcomes of postoperative radiotherapy (PORT) patients who underwent radical prostatectomy for localized prostate cancer. Materials and Methods Localized prostate cancer patients who...
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Gastric Complications after Adjuvant Radiotherapy for Breast Cancer

Cho WK, Choi DH, Park W, Kim H, Kim S, Shin MH, Cha H

PURPOSE: In some patients who receive adjuvant radiotherapy (RT) for the left breast, the stomach is located inside the RT field. This study investigates the incidence of gastric complications following...
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Risk factors for locoregional recurrence in patients with pathologic T3N0 rectal cancer with negative resection margin treated by surgery alone

Baek JY, Yu JI, Park HC, Choi DH, Yoo GS, Cho WK, Lee WY, Yun SH, Cho YB, Park YA, Kim HC

PURPOSE: This study aimed to identify prognostic factors for locoregional recurrence (LRR) in pT3N0 rectal cancer patients who were treated with surgery alone and had negative resection margin including circumferential...
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The Benefit of Post-Mastectomy Radiotherapy in ypN0 Patients after Neoadjuvant Chemotherapy According to Molecular Subtypes

Cho WK, Park W, Choi DH, Kim YB, Kim JH, Kim SS, Kim K, Kim JH, Ahn SJ, Lee SY, Lee J, Kim SW, Kwon J, Ahn KJ

PURPOSE: The benefit of post-mastectomy radiation therapy (PMRT) in patients with breast cancer who achieve ypN0 following neoadjuvant chemotherapy (NAC) has not yet been established. This study aimed to identify...
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COPD as a Disease of Immunosenescence

Cho WK, Lee CG, Kim LK

Although chronic obstructive pulmonary disease (COPD) is regarded as a chronic inflammatory lung disease, the disease mechanism is still not known. Intriguingly, aging lungs are quite similar to COPD-affected lungs...
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Feasibility of Selective Neck Irradiation with Lower Elective Radiation Dose in Treating Nasopharynx Cancer Patients

Cho WK, Oh D, Lee E, Kim TG, Lee H, Nam H, Noh JM, Ahn YC

PURPOSE: This study aimed to report the clinical outcomes following selective neck irradiation (SNI) with lower elective radiation therapy (RT) dose in treating nasopharyngeal cancer (NPC) patients. MATERIALS AND METHODS: A...
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Factors affecting height velocity in normal prepubertal children

Lee JH, Kim SK, Lee EK, Ahn MB, Kim SH, Cho WK, Cho KS, Jung MH, Suh BK

PURPOSE: To analyze the effects of clinical and laboratory factors, including insulin-like growth factor (IGF) levels, on the height velocity of normal prepubertal children. METHODS: Ninety-five healthy prepubertal children (33 boys,...
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Cancer in thyroid nodules with fine-needle aspiration in Korean pediatric populations

Jang JH, Park SH, Cho KS, Cho WK, Suh YJ, Suh BK, Koh DK

PURPOSE: To determine the prevalence and clinical findings of benign thyroid nodules and cancer in Korean pediatric patients with thyroid nodules. METHODS: We investigated the medical records of 134 patients aged...
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Which Patients with Left Breast Cancer Should be Candidates for Heart-Sparing Radiotherapy?

Cho WK, Park W, Choi DH, Cha H, Nam SJ, Kim SW, Lee JE, Yu J, Im YH, Ahn JS, Park YH, Kim JY

PURPOSE: This study aimed to identify risk factors that have significant interaction with radiation exposure to the heart, and thus to determine candidates for heart-sparing radiotherapy (RT) among women with...
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HbA1c Cutoff for Prediabetes and Diabetes Based on Oral Glucose Tolerance Test in Obese Children and Adolescents

Nam HK, Cho WK, Kim JH, Rhie YJ, Chung S, Lee KH, Suh BK

BACKGROUND: Oral glucose tolerance test (OGTT) is a traditional diagnostic tool for diabetes. Hemoglobin A1c (HbA1c) is an alternative method used in adults; however, its application in youths has been...
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Nonautoimmune congenital hyperthyroidism due to p.Asp633Glu mutation in the TSHR gene

Cho WK, Ahn MB, Jang W, Chae H, Kim M, Suh BK

Most cases of congenital hyperthyroidism are autoimmune forms caused by maternal thyroid stimulating antibodies. Nonautoimmune forms of congenital hyperthyroidism caused by activating mutations of the thyrotropin receptor (TSHR) gene are...
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The effect of overweight on the luteinizing hormone level after gonadorelin stimulation test in girls with idiopathic central precocious puberty

Lee HY, Lee YJ, Ahn MB, Cho WK, Suh BK

PURPOSE: We investigated the effect of overweight on luteinizing hormone (LH) levels after a gonadorelin stimulation test in Korean girls with idiopathic central precocious puberty (CPP). METHODS: Medical records of 234...
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The association between skeletal maturation and adrenal androgen levels in obese children and adolescents

Kim SE, Jang JW, Ahn MB, Kim SH, Cho WK, Cho KS, Park SH, Jung MH, Suh BK

PURPOSE: This study aimed to investigate the association between skeletal maturation and adrenal androgen levels in obese children and adolescents. METHODS: Fifty-three children and adolescents (aged 7–15 years) diagnosed as obese...
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A Case of Pseudohypoparathyroidism Type Ib Caused by Aberrant Methylation in the GNAS Complex Locus

Jo SJ, Han E, Jang W, Chae H, Kim Y, Lee GD, Cho WK, Suh BK, Kim M

Pseudohypoparathyroidism (PHP) is a rare disorder caused by genetic and epigenetic aberrations in the GNAS complex locus resulting in impaired expression of stimulatory G protein (Gsα). PHP type Ib (PHP-Ib)...
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Growth without growth hormone in combined pituitary hormone deficiency caused by pituitary stalk interruption syndrome

Lee SS, Han AL, Ahn MB, Kim SH, Cho WK, Cho KS, Park SH, Jung MH, Suh BK

Growth hormone (GH) is an essential element for normal growth. However, reports of normal growth without GH have been made in patients who have undergone brain surgery for craniopharyngioma. Normal...
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