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Clinical Application of Sequential Epigenetic Analysis for Diagnosis of Silver–Russell Syndrome

Kim SY, Shin CH, Lee YA, Shin CH, Yang SW, Cho TJ, Ko JM

Background: Silver-Russell syndrome (SRS) is a pre- or post-natal growth retardation disorder caused by (epi)genetic alterations. We evaluated the molecular basis and clinical value of sequential epigenetic analysis in pediatric...
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Functional Outcomes of Hip Arthroscopy for Pediatric and Adolescent Hip Disorders

Lim C, Cho TJ, Shin CH, Choi IH, Yoo WJ

BACKGROUND: There is a paucity of literature on the use of hip arthroscopy for pathologic conditions in skeletally immature patients. Thus, the indications and safety of the procedure are still...
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Management of Osteogenesis Imperfecta: A Multidisciplinary Comprehensive Approach

Cho TJ, Ko JM, Kim H, Shin HI, Yoo WJ, Shin CH

Osteogenesis imperfecta (OI) is characterized by recurring fractures and limb and spine deformities. With the advent of medical therapeutics and the discovery of causative genes, as well as the introduction...
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Characterization and Differentiation of Circulating Blood Mesenchymal Stem Cells and the Role of Phosphatidylinositol 3-Kinase in Modulating the Adhesion

Park YK, Heo SJ, Koak JY, Park GS, Cho TJ, Kim SK, Cho J

Bone marrow mesenchymal stem cells (BM MSCs) can differentiate into multi-lineage tissues. However, obtaining BM MSCs by aspiration is difficult and can be painful; therefore peripheral blood (PB) MSCs might...
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A Case of Familial Spondyloenchondrodysplasia with Immune Dysregulation Masquerading as Moyamoya Syndrome

Lee JS, Lim BC, Kim KJ, Kim SK, Kim OH, Kim JG, Park SG, Cho TJ, Chae JH

No abstract available.
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Diagnosis and Management of Hip Dislocation in Patients with Kabuki Syndrome

Lim C, Jung ST, Shin CH, Park MS, Yoo WJ, Chung CY, Choi IH, Ko JM, Cho TJ

BACKGROUND: Kabuki syndrome is a rare genetic disorder characterized by distinct dysmorphic facial features, growth deficiency, intellectual disabilities, unusual dermatoglyphic patterns, and skeletal abnormalities. The incidence of hip dislocation in...
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Mycobacterium bovis Osteitis Following Immunization with Bacille Calmette-Guérin (BCG) in Korea

Choi YY, Han MS, Lee HJ, Yun KW, Shin CH, Yoo WJ, Cho TJ, Cheon JE, Park KU, Choi EH

BACKGROUND: Mycobacterium bovis Bacille Calmette-Guérin (BCG) osteitis, a rare complication of BCG vaccination, has not been well investigated in Korea. This study aimed to evaluate the clinical characteristics of BCG...
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Production and Storage of Virus Simulants

Shin IS, Kim D, Yang SJ, Lim BC, Cha Y, Kim S, Cho TJ

We have examined isolation and identification protocols for three virus simulant candidates to biological warfare agents. MS2 phage, a simulant for yellow fever virus and Hantaan virus, was propagated using...
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Regarding Camurati-Engelmann Disease: In Reply

Yuldashev , Shin CH, Kim YS, Jang WY, Park MS, Chae JH, Yoo WJ, Choi IH, Kim OH, Cho TJ

No abstract available.
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Cysteine-Added Mutants of Turnip Yellow Mosaic Virus

Shin IS, Kim D, Cho TJ

Native turnip yellow mosaic virus (TYMV) is relatively unreactive to maleimide agents, indicating few reactive thiol groups on TYMV. In the present study, we aimed to construct TYMV mutants that...
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Replication of Recombinant Flock House Virus RNA Encapsidated by Turnip Yellow Mosaic Virus Coat Proteins in Nicotiana benthamiana

Kim D, Cho TJ

It was previously observed that recombinant flock house virus (FHV) RNA1 was efficiently packaged into turnip yellow mosaic virus (TYMV), provided that the TYMV coat protein (CP) sequence was present...
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Orthopedic Manifestations of Type I Camurati-Engelmann Disease

Yuldashev , Shin CH, Kim YS, Jang WY, Park MS, Chae JH, Yoo WJ, Choi IH, Kim OH, Cho TJ

BACKGROUND: Camurati-Engelmann disease (CED) is a rare genetic skeletal disorder characterized by limb pain, muscle emaciation and weakness, and cortical thickening of the diaphysis of long bones. It is caused...
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N-terminal Extension of Coat Protein of Turnip Yellow Mosaic Virus has Variable Effects on Replication, RNA Packaging, and Virion Assembly Depending on the Inserted Sequence

Chae KH, Kim D, Cho TJ

Turnip yellow mosaic virus (TYMV) is a non-enveloped icosahedral virus composed of 20 kDa single coat proteins. In this study, we modified the TYMV coat protein (CP) ORF by inserting...
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Demineralized Bone Matrix Injection in Consolidation Phase Enhances Bone Regeneration in Distraction Osteogenesis via Endochondral Bone Formation

Kim JB, Lee DY, Seo SG, Kim EJ, Kim JH, Yoo WJ, Cho TJ, Choi IH

BACKGROUND: Distraction osteogenesis (DO) is a promising tool for bone and tissue regeneration. However, prolonged healing time remains a major problem. Various materials including cells, cytokines, and growth factors have...
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Incidental Findings on Knee Radiographs in Children and Adolescents

Seo SG, Sung KH, Chung CY, Lee KM, Lee SY, Choi Y, Kim TG, Baek JK, Kwon SS, Kwon DG, Choi IH, Cho TJ, Yoo WJ, Park MS

BACKGROUND: Despite the wide use of knee radiography in children and adolescent patients visiting the outpatient clinic, there has been no analysis about the prevalence and type of incidental findings...
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Genome Size Constraint in Replication and Packaging of Turnip Yellow Mosaic Virus

Kim HB, Chae KH, Cho TJ

Turnip yellow mosaic virus (TYMV) is a spherical plant virus that has a single 6.3 kb positive strand RNA as a genome. Previously, we have made the recombinant TYMV construct...
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Determining the Best Treatment for Simple Bone Cyst: A Decision Analysis

Lee SY, Chung CY, Lee KM, Sung KH, Won SH, Choi IH, Cho TJ, Yoo WJ, Yeo JH, Park MS

BACKGROUND: The treatment of simple bone cysts (SBC) in children varies significantly among physicians. This study examined which procedure is better for the treatment of SBC, using a decision analysis...
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Living Donor Liver Transplantation for an Infant with Osteogenesis Imperfecta and Intrahepatic Cholestasis: Report of a Case

Choi Y, Yi NJ, Ko JS, Ko JM, Jin US, Kim HS, Lee KH, Cho TJ, Suh SW, Yoo T, Lee KW, Suh KS

Osteogenesis imperfecta (OI) is a group of genetic disorders characterized by bone fragility and connective tissue manifestations. We report a successful liver transplantation (LT) in an 8-month-old boy with OI...
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Anterior Knee Pain in Patients with Cerebral Palsy

Choi Y, Lee SH, Chung CY, Park MS, Lee KM, Sung KH, Won SH, Lee IH, Choi IH, Cho TJ, Yoo WJ, Lee SY

BACKGROUND: The aim of this study was to identify the risk factors for anterior knee pain in patients with cerebral palsy. METHODS: This prospective study investigated the risk factors for anterior...
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Incidence Patterns of Pediatric and Adolescent Orthopaedic Fractures According to Age Groups and Seasons in South Korea: A Population-Based Study

Park MS, Chung CY, Choi IH, Kim TW, Sung KH, Lee SY, Lee SH, Kwon DG, Park JW, Kim TG, Choi Y, Cho TJ, Yoo WJ, Lee KM

BACKGROUND: Fractures which need urgent or emergency treatment are common in children and adolescents. This study investigated the incidence patterns of pediatric and adolescent orthopaedic fractures according to age groups...
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