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Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway

Yeo EJ, Eum WS, Yeo HJ, Choi YJ, Sohn EJ, Kwon HJ, Kim DW, Kim DS, Cho SW, Park J, Han KH, Lee KW, Park JK, Shin MJ, Choi SY

Oxidative stress plays a crucial role in the development of neuronal disorders including brain ischemic injury. Thioredoxin 1 (Trx1), a 12 kDa oxidoreductase, has anti-oxidant and anti-apoptotic functions in various...
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Long-term Outcomes of Clopidogrel Monotherapy versus Prolonged Dual Antiplatelet Therapy beyond 12 Months after Percutaneous Coronary Intervention in High-risk Patients

Kim DY, Cho SW, Park KT, Ahn JH, Park TK, Jang YH, Choi KH, Lee JM, Yang JH, Song YB, Choi JH, Choi SH, Gwon HC, Lee SH, Hahn JY

Background: There are no data on comparison between clopidogrel monotherapy and prolonged dual antiplatelet therapy (DAPT) in patients at high-risk undergoing percutaneous coronary intervention (PCI). Methods: Of 2,082 consecutive patients undergoing...
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Validation of Olfactory Questionnaire in Koreans: an Alternative for Conventional Psychophysical Olfactory Tests

Kim JW, Kim Hs, Kim M, Kim SH, Cho SW, Kim JY

Background: The patients with coronavirus disease 2019 (COVID-19), a worldwide pandemic infection, frequently complain of olfactory disorders. However, psychophysical olfactory tests performed by an examiner are very difficult in these...
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Regional and Chronological Variation of Chemosensory Dysfunction in COVID-19: a Meta-Analysis

Kim JW, Han SC, Jo HD, Cho SW, Kim JY

Background: Olfactory and gustatory dysfunction are frequently reported in patients with coronavirus disease 2019 (COVID-19). However, the reported prevalence of olfactory and/or gustatory dysfunction varies widely, and the reason for...
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Prognostic Value of Alpha-Fetoprotein in Patients Who Achieve a Complete Response to Transarterial Chemoembolization for Hepatocellular Carcinoma

Lee JS, Chon YE, Kim BK, Park JY, Kim DY, Ahn SH, Han KH, Kang W, Choi MS, Gwak GY, Paik YH, Lee JH, Koh KC, Paik SW, Kim HY, Kim TH, Yoo K, Ha Y, Kim MN, Lee JH, Hwang SG, Kim SS, Cho HJ, Cheong JY, Cho SW, Park SH, Heo NY, Hong YM, Yoon KT, Cho M, Park JG, Kang MK, Park SY, Kweon YO, Tak WY, Jang SY, Sinn DH, Kim SU, The Korean TACE Study Group

Purpose: Alpha-fetoprotein (AFP) is a prognostic marker for hepatocellular carcinoma (HCC). We investigated the prognostic value of AFP levels in patients who achieved complete response (CR) to transarterial chemoembolization (TACE)...
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Antioxidant and hepatoprotective effects of Korean ginseng extract GS-KG9 in a D-galactosamine-induced liver damage animal model

Jo YH, Lee H, Oh MH, Lee GH, Lee YJ, Lee JS, Kim MJ, Kim WY, Kim JS, Yoo DS, Cho SW, Cha SW, Pyo MK

BACKGROUND/OBJECTIVES: This study was designed to investigate the improvement effect of white ginseng extract (GS-KG9) on D-galactosamine (Ga1N)-induced oxidative stress and liver injury. SUBJECTS/METHODS: Sixty Sprague-Dawley rats were divided into 6...
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Effect of Age on Laparoscopic Surgery and Postoperative Chemotherapy in Elderly Patients With Colorectal Cancer

Kim HH, Ihn MH, Lee YH, Lee J, Yun S, Cho SW

Purpose: We aimed to evaluate the postoperative complications of laparoscopic colorectal cancer (CRC) surgery and the adverse events of postoperative chemotherapy in elderly patients compared to younger patients and to...
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Clinical Implications of Early Exercise Treadmill Testing after Percutaneous Coronary Intervention in the Drug-eluting Stent Era

Cho SW, Yang JH, Park TK, Lee JM, Song YB, Hahn JY, Choi JH, Gwon HC, Lee SH, Choi SH

Background: Limited data are available on the clinical meaning of early routine exercise treadmill testing (ETT) after percutaneous coronary intervention (PCI) in the drug-eluting stent era. We aimed to determine...
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Performance Evaluation of a Point of Care SelexOnTM B-Type Natriuretic Peptide Immunoassay

Jekarl DW, Lee S, Choi H, Cho SW, Park Hi

Background: This study was conducted to evaluate the analytical performance of the SelexOnTM B-type natriuretic peptide (BNP) assay (Osang Healthcare Inc., Korea), a new rapid lateral flow immunoassay for point...
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The Prevalence and Incidence of Insomnia in Korea during 2005 to 2013

Chung S, Cho SW, Jo MW, Youn S, Lee J, Sim CS

Objective The aim of this study was to estimate the progress of insomnia prevalence and incidence over the past several years. Also, this study compared survival rates between individuals with...
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Clinical Characteristics Other Than Intralesional Hyperdensity May Increase the Preoperative Diagnostic Accuracy of Maxillary Sinus Fungal Ball

Cha H, Song Y, Bae YJ, Won TB, Kim JW, Cho SW, Rhee CS

Objectives. This study aimed to evaluate the clinical characteristics of maxillary sinus fungus ball (MFB) to increase the preoperative diagnostic accuracy. Methods. A retrospective review of 247 patients who underwent endoscopic...
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Overexpression of Nrf2 promotes colon cancer progression via ERK and AKT signaling pathways

Lee YJ, Kim WI, Bae JH, Cho MK, Lee SH, Nam HS, Choi IH, Cho SW

Purpose: We investigated the expression of Nrf2 in colorectal cancer and its correlation with clinicopathological characteristics as well as mechanisms and roles of Nrf2 expression including cell signaling pathway, survival,...
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Evaluation of pneumonia management effectiveness associated withinternal medicine management changes in the emergency department:a retrospective cohort study using a historically controlled group

Yoo JW, Ryu S, Jeong WJ, Cho YC, Ahn HJ, Cho SW, Oh SK, Park JS, Yoo YH

  • KMID: 2500274
  • J Korean Soc Emerg Med.
  • 2020 Apr;31(2):246-253.
Objective: In Korea, many hospitals have recently changed the process of internal medicine management in the emergency department (ED) because of reduced manpower, raising concerns regarding the decreased quality of medical care....
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Characteristics of the pneumonia patients transferred from long-term care hospitals:retrospective study of one regional emergency medical center

Kim HI, Ryu S, Jeong WJ, Cho YC, Ahn HJ, Cho SW, Oh SK, Park JS, You YH

  • KMID: 2500270
  • J Korean Soc Emerg Med.
  • 2020 Apr;31(2):210-220.
Objective: This study investigated the characteristics of elderly pneumonia patients transferred from long-term care hospitals (LTCH). Methods: The initial emergency department (ED) data of patients, who were transferred from other hospitals and...
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Multifaceted Actions of Succinate as a Signaling Transmitter Vary with Its Cellular Locations

Guo Y, Cho SW, Saxena D, Li X

Since the identification of succinate's receptor in 2004, studies supporting the involvement of succinate signaling through its receptor in various diseases have accumulated and most of these investigations have highlighted...
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Management of Skull Base Osteoradionecrosis

Cho SW, Won TB

Osteoradionecrosis of the skull base (SB-ORN) is a serious potentially lethal complication after radiotherapy in the head and neck region and is therefore considered one of the most challenging clinical...
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Successful percutaneous coronary intervention with extracorporeal membrane oxygenation support after right coronary artery dissection in an eisenmenger syndrome patient

Kim BG, Cho SW, Nah JC

The presentation of coronary artery disease in a patient with Eisenmenger syndrome (ES) is relatively rare. Cardiogenic shock due to coronary artery dissection during percutaneous coronary intervention (PCI) can be...
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Thyroid Metastasis from Breast and Lung Cancer in Patients with Underlying Hashimoto’s Thyroiditis

Im SG, Choi H, Im SA, Cho SW

Metastatic disease involving the thyroid gland is uncommon. Thyroid metastases has been previously described from several primary cancers of lung, breast, and kidney. Because of the lower incidence and ambiguous...
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Subclinical and Tiny Myocardial Injury within Upper Reference Limit of Cardiac Troponin Should Not Be Ignored after Noncardiac Surgery

Cho SW

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Long-term Stability after Reduction of Mandible Fracture by Keyhole Plate: Evaluation at the Time of Plate Removal

Cheon KJ, Cho SW, Jang WS, Kim JW, Yang BE

Background: Various types of miniplates have been developed and used for the reduction of facial bone fractures. We introduced Yang’s Keyhole (YK) plate, and reported on its short-term stability. The...
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