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The proper concentrations of dextrose and lidocaine in regenerative injection therapy: in vitro study

Woo MS, Park J, Ok SH, Park M, Sohn JT, Cho MS, Shin IW, Kim YA

Background: Prolotherapy is a proliferation therapy as an alternative medicine. A combination of dextrose solution and lidocaine is usually used in prolotherapy. The concentrations of dextrose and lidocaine used in...
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Impact of Angiotensin Receptor Blockers, Beta Blockers,Calcium Channel Blockers and Thiazide Diuretics on Survivalof Ovarian Cancer Patients

Cho MA, Jeong SY, Sohn I, Kim MS, Kang JH, Paik ES, Lee YY, Choi CH

Purpose We investigated the impact of four types of antihypertensive medications, angiotensin receptor blockers (ARBs), beta blockers (BBs; both selective and non-selective), calcium channel blockers (CCBs), and thiazide diuretics (TDs) on survival outcomes...
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Finite element analysis of long-term changes of the breast after augmentation mammoplasty: Implications for implant design

Myung Y, Lee JG, Cho M, Heo CY

The development of breast implant technology continues to evolve over time, but changes in breast shape after implantation have not been fully elucidated. Thus, we performed computerized finite element analysis...
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Streptomyces Cytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic Agents

Cho MA, Han S, Lim YR, Kim V, Kim H, Kim D

The study of the genus Streptomyces is of particular interest because it produces a wide array of clinically important bioactive molecules. The genomic sequencing of many Streptomyces species has revealed...
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Functional Characterization of Pharmcogenetic Variants of Human Cytochrome P450 2C9 in Korean Populations

Cho MA, Yoon JG, Kim V, Kim H, Lee R, Lee MG, Kim D

Human cytochrome P450 2C9 is a highly polymorphic enzyme that is required for drug and xenobiotic metabolism. Here, we studied eleven P450 2C9 genetic variants—including three novel variants F69S, L310V,...
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Decline in the Incidence of All-Cause and Alzheimer's Disease Dementia: a 12-Year-Later Rural Cohort Study in Korea

Park JE, Kim BS, Kim KW, Hahm BJ, Sohn JH, Suk HW, Lee JY, Cho MJ

BACKGROUND: There has been no study on the time trends of dementia incidence in Korea. We report the 5-year incidence and its correlates of all-cause and Alzheimer's disease (AD) dementia,...
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A Study on Factors Affecting Suicidal Tendency of the Elderly Living Alone on Care Services

Seo H, Sohn JH, Cho SJ, Sung SJ, Cho MJ, Ahn SH

OBJECTIVES: The high suicide rate has risen as a main concern in South Korea. Given the complexity of the mechanism resulting in complete suicide, studies targeting various populations are needed...
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Association of Body Mass Index with Suicide Behaviors, Perceived Stress, and Life Dissatisfaction in the Korean General Population

Kim H, Jeon HJ, Bae JN, Cho MJ, Cho SJ, Lee H, Hong JP

OBJECTIVE: The purpose of the present study was to investigate the association between Body Mass Index, suicide, perceived stress, and life dissatisfaction in a general population sample of Korean adults. METHODS:...
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The main autoimmune and nonautoimmune etiologies of endogenous hyperthyroidism do not seem to influence the increased prevalence of morphometric vertebral fractures and osteoporosis in Portuguese men

Barbosa AP, Mascarenhas MR, Bicho M, Janeiro J, Oliveira A

OBJECTIVES: The purpose of this study was to evaluate the effects of hyperthyroidism and their etiology on bone mineral density (BMD), on body soft tissue composition, on the prevalence of...
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Effects of Education on Differential Item Functioning on the 15-Item Modified Korean Version of the Boston Naming Test

Kim BS, Lee DW, Bae JN, Kim JH, Kim S, Kim KW, Park JE, Cho MJ, Chang SM

OBJECTIVE: Education is expected to have an effect on differential item functioning (DIF) on the 15-item Modified Boston Naming Test in the Korean version of the Consortium to Establish a...
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Mental-Physical Comorbidity in Korean Adults: Results from a Nationwide General Population Survey in Korea

Kim JH, Chang SM, Bae JN, Cho SJ, Lee JY, Kim BS, Cho MJ

OBJECTIVE: The aims of this study were to estimate the prevalence of mental-physical comorbidity and health-threatening risk factors in subjects with mental disorders, and the risks of mental disorders in...
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Difference of Somatic Symptoms between Anxiety Disorder and Major Depressive Disorder and Their Domainal Association with Suicidal Idealization, Plan and Attempts

Ahn JS, Kim EY, Cho MJ, Hong JP, Hahm BJ, Chung IW, Ahn JH, Jeon HJ, Seong SJ, Lee DW

OBJECTIVES: The aim of this study is to evaluate difference of somatic symptoms of anxiety disorder and major depressive disorder and domainal association with suicidal idealization, plan, and attempts. METHODS: A...
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Association of Overweight with the Prevalence of Lifetime Psychiatric Disorders and Suicidality: General Population-based Study in Korea

Kim BS, Chang SM, Seong SJ, Park JE, Park S, Hong JP, Bae JN, Cho SJ, Hahm BJ, Lee DW, Park JI, Lee JY, Jeon HJ, Cho MJ

Many epidemiological studies suggest that overweight is associated with an elevated risk of psychiatric disorders and suicidal tendency. However, findings vary across studies, and some have contradictory results. We investigated...
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Evaluation of a Functional Model of Acquired Capability for Suicide in a Nationwide Sample of Korean Adults

Lee JD, Cho MJ, Sohn JH, Park S, Seong S, Ahn JH, Hahm BJ, Hong JP

OBJECTIVE: We examined a functional model of acquired capability for suicide, which was elaborated from the “Interpersonal-Psychological Theory of Suicide”. METHODS: A total of 6,027 Korean community subjects were recruited from...
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Association between DSM-IV Anxiety Disorders and Suicidal Behaviors in a Community Sample of South Korean Adults

Cho SJ, Hong JP, Lee JY, Im JS, Na KS, Park JE, Cho MJ

OBJECTIVE: There are conflicting reports about whether individual anxiety disorders are independently associated with suicidal ideation and suicide attempts. We examined whether anxiety disorders are related to suicidal ideation and...
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Sociodemographic Factors and Comorbidities Associated with Remission from Alcohol Dependence: Results from a Nationwide General Population Survey in Korea

Han SY, Cho MJ, Won S, Hong JP, Bae JN, Cho SJ, Park JI, Lee JY, Jeon HJ, Chang SM

OBJECTIVE: The lifetime prevalence of alcohol dependence in South Korea remains higher than other countries. The aim of our study is to identify factors associated with remission from alcohol dependence. METHODS:...
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Development of North Korean Version of the Composite International Diagnostic Interview

Lee T, Ahn MH, Jun JY, Han JM, Lee SH, Hahm BJ, Cho MJ, Hong JP

OBJECTIVES: The aim of the study was to develop a North Korean version of the Composite International Diagnostic Interview (NK-CIDI) and to evaluate the reliability and validity of NK-CIDI. METHODS: Subjects...
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Childhood Exposure to Psychological Trauma and the Risk of Suicide Attempts: The Modulating Effect of Psychiatric Disorders

Park S, Hong JP, Jeon HJ, Seong S, Cho MJ

OBJECTIVE: We examined whether childhood exposure to psychological trauma is associated with greater suicidality and whether specific psychiatric disorders modulate this association in a representative sample of Korean adults. METHODS: The...
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Prevalence and Correlates of DSM-IV Mental Disorders in South Korean Adults: The Korean Epidemiologic Catchment Area Study 2011

Cho MJ, Seong SJ, Park JE, Chung IW, Lee YM, Bae A, Ahn JH, Lee DW, Bae JN, Cho SJ, Park JI, Son J, Chang SM, Hahm BJ, Lee JY, Sohn JH, Kim JS, Hong JP

OBJECTIVE: The aim of this study was to estimate the prevalence and correlates of mental disorders in Korean adults. METHODS: Door to door household surveys were conducted with community residents aged...
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Steep Decrease of Gender Difference in DSM-IV Alcohol Use Disorder: A Comparison of Two Nation-wide Surveys Conducted 10 Years Apart in Korea

Seong SJ, Hong JP, Hahm BJ, Jeon HJ, Sohn JH, Lee JY, Cho MJ

While decreasing trend in gender differences in alcohol use disorders was reported in Western countries, the change in Asian countries is unknown. This study aims to explore the shifts in...
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