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Proprotein convertase subtilisin/kexin type 9 inhibition in cardiovascular disease: current status and future perspectives

Cho KH, Hong YJ

Proprotein convertase subtilisin/kexin type 9 (PCSK 9) targets the degradation of low-density lipoprotein (LDL) receptors; it has been proved that its inhibition improves cardiovascular outcomes in patients with established atherosclerotic...
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Clinical Benefit of Statins in Korean Patients with Acute Myocardial Infarction: Experience of the Korea Acute Myocardial Infarction Registry

Cho KH, Jeong MH

Statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor) are among the most important medications for treating patients with acute myocardial infarction (AMI). Herein, we review the clinical benefit and future scope of statin...
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Repeated Dry Sauna Therapy Improves Quality of Life in Obese Korean People

Choi HS, Kwon H, Cho KH, Thuc LC, Park SY, Kim NH, Kim WJ, Kim YK, Jeon WS, Lee JA, Kim HC, Cho EH

Background: Dry sauna treatments improve the quality of life for chronic pain, congestive heart failure, and type 2 diabetes patients. This study aimed to determine whether dry sauna therapy improved...
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Image of Statin-Induced Rhabdomyolysis

Kim MC, Ahn Y, Cho KH, Sim DS, Hong YJ, Kim JH, Jeong MH

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A Fully Immersive Virtual Reality Method for Upper Limb Rehabilitation in Spinal Cord Injury

Lim DY, Hwang DM, Cho KH, Moon CW, Ahn SY

Objective To determine whether a fully immersive virtual reality (VR) intervention combined with conventional rehabilitation (CR) can improve upper limb function more than CR alone in patients with spinal cord...
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Infolding Distortion of Evolut R Valve after Transcatheter Aortic Valve Replacement

Kim MC, Kim JH, Cho KH, Sim DS, Hong YJ, Ahn Y, Jeong MH

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3-h drain clamping is not effective to reduce total blood loss after primary total knowledge

Park D, Choi YH, Cho KH, Koh HS

Purpose: Total knee arthroplasty (TKA) is a clinically efficacious surgical option for end-stage knee osteoarthritis. However, TKA increases the risk of serious bleeding and blood transfusion. The objective of this study...
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Long-Term Clinical Outcome according to Changes of Glomerular Filtration Rate in AMI Patients with Multivessel Disease after Percutaneous Coronary Intervention

Han X, Bai L, Jeong MH, Hyun DY, Cho KH, Kim Y, Kim MC, Sim DS, Hong YJ, Kim JH, Ahn Y

Glomerular filtration rate (GFR) is an important indicator of renal failure. However, regarding delta GFR in acute myocardial infarction (AMI) is rare. In this study, it was examined whether the...
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Associations of Physical Activity and Sitting Time with Serum Vitamin D Status in Korean Adults: Results from the 2014 Korea National Health and Nutrition Examination Survey

Choo J, Nam GE, Park J, Park CM, Lee SJ, Lee M, Kim J, Shin JH, Huh Y, Kim W, Kwon Y, Kim YH, Cho KH

Background: Recent evidence has reported the relationships between 25-hydroxyvitamin D (25[OH]D) insufficiency and chronic diseases. This study examined the association of physical activity and sitting time with vitamin D status. Methods:...
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Inhibition of RIPK3 Pathway Attenuates Intestinal Inflammation and Cell Death of Inflammatory Bowel Disease and Suppresses Necroptosis in Peripheral Mononuclear Cells of Ulcerative Colitis Patients

Lee SH, Kwon Jy, Moon J, Choi J, Jhun J, Jung K, Cho KH, Darlami O, Lee HH, Jung ES, Shin DY, Lee BI, Cho ML

Receptor-interacting serine/threonine-protein kinase (RIPK) 3 is a member of the TNF receptor-I signaling complex and mediates necroptosis, an inflammatory cell death. Ulcerative colitis (UC) is an excessive inflammatory disease caused...
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Association of Serum Vitamin D Status with Prediabetes and Prehypertension in Korean Adults: An Analysis of the 2013–2015 Korea National Health and Nutrition Examination Survey Data

Park J, Nam GE, Choo J, Park H, Lee SJ, Park S, Chung S, Lee ES, Huh Y, Kim W, Kwon Y, Kim YH, Cho KH

Background: Recent studies have indicated that vitamin D deficiency is associated with diabetes and hypertension in adults. However, this association has not been sufficiently studied in cases of prediabetes and...
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Impact of Anticoagulation Intensity in Korean Patients with Atrial Fibrillation: Is It Different from Western Population?

Lee KH, Cho JG, Lee N, Cho KH, Jeong HK, Park H, Kim Y, Cho JY, Kim MC, Sim DS, Yoon HJ, Yoon N, Kim KH, Hong YJ, Park HW, Ahn Y, Jeong MH, Park JC

BACKGROUND AND OBJECTIVES: Although anticoagulation with warfarin is recommended as an international normalized ratio (INR) of prothrombin time between 2.0 and 3.0 and mean time in the therapeutic range (TTR)...
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Open channel block of Kv1.4 potassium channels by aripiprazole

Park J, Cho KH, Lee HJ, Choi JS, Rhie DJ

Aripiprazole is a quinolinone derivative approved as an atypical antipsychotic drug for the treatment of schizophrenia and bipolar disorder. It acts as with partial agonist activities at the dopamine D2...
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Layer-specific serotonergic induction of long-term depression in the prefrontal cortex of rats

Shin D, Cho KH, Joo K, Rhie DJ

Layer 2/3 pyramidal neurons (L2/3 PyNs) of the cortex extend their basal dendrites near the soma and as apical dendritic tufts in layer 1, which mainly receive feedforward and feedback...
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Clinical Outcomes of Postoperative Radiotherapy Following Radical Prostatectomy in Patients with Localized Prostate Cancer: A Multicenter Retrospective Study (KROG 18-01) of a Korean Population

Lee SU, Cho KH, Park W, Cho WK, Kim JS, Wee CW, Kim YS, Kim JH, Nam TK, Cho J, Jeong SM, Kim Y, Shim SJ, Choi Y, Kim JS

Purpose The purpose of this study was to investigate the clinical outcomes of postoperative radiotherapy (PORT) patients who underwent radical prostatectomy for localized prostate cancer. Materials and Methods Localized prostate cancer patients who...
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Nervus terminalis and nerves to the vomeronasal organ: a study using human fetal specimens

Jin ZW, Cho KH, Shibata S, Yamamoto M, Murakami G, Rodríguez-Vázquez JF

The human nervus terminalis (terminal nerve) and the nerves to the vomeronasal organ (VNON) are both associated with the olfactory nerves and are of major interest to embryologists. However, there...
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Snuffbox Approach for Coronary Chronic Total Occlusion Intervention Using a 7-French Sheath

Kim Y, Hyun DY, Cho KH, Kim MC, Sim DS, Hong YJ, Kim JH, Ahn Y, Jeong MH

No abstract available.
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Layer-specific cholinergic modulation of synaptic transmission in layer 2/3 pyramidal neurons of rat visual cortex

Cho KH, Lee SY, Joo K, Rhie DJ

It is known that top-down associative inputs terminate on distal apical dendrites in layer 1 while bottom-up sensory inputs terminate on perisomatic dendrites of layer 2/3 pyramidal neurons (L2/3 PyNs)...
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Delayed Ipsilateral Regional Cortical Injury after Carotid Endarterectomy

Sung JH, Moon J, Cho KH, Yu S

No abstract available.
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Effect of STAT3 on Lysophosphatidic Acid-Induced Oral Cancer Cell Invasion

Song ZH, Cho KH, Kim JY, Lee HY

BACKGROUND: Oral cancer has a high incidence worldwide and has been closely associated with smoking, alcohol, and infection by the human papillomavirus. Metastasis is highly important for oral cancer survival....
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