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Effects of Health Disorder Signals on Irritable Bowel Syndrome and Urination Disorders: Focusing on Door-to-Door Salespeople and Women Who have Experienced Symptoms of Irritable Bowel Syndrome

Lee W, Cho DY, Choi SH

Purpose: This study investigated the effects of Health Disorder Signals on irritable bowel syndrome (IBS) and urination disorders, and the relationship between IBS and urination disorders. Methods: A questionnaire survey...
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Bioequivalence of the pharmacokinetics between tofacitinib aspartate and tofacitinib citrate in healthy subjects

Shin W, Yang AY, Yun H, Cho DY, Park KH, Shin H, Kim A

Tofacitinib is an oral disease-modifying anti-rheumatic drug to selectively inhibit Janus kinases. Tofacitinib is a representative small molecule inhibitor that is used to treat many diseases including rheumatoid arthritis and...
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Effects of Combined Upper Limb Robotic Therapy in Patients With Tetraplegic Spinal Cord Injury

Jung JH, Lee HJ, Cho DY, Lim JE, Lee BS, Kwon SH, Kim HY, Lee SJ

OBJECTIVE: To confirm the effects of combined upper limb robotic therapy (RT) as compared to conventional occupational therapy (OT) in tetraplegic spinal cord injury (SCI) patients and to suggest the...
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Biological Aspects of Aggression and Violence in Schizophrenia

Cho W, Shin WS, An I, Bang M, Cho DY, Lee SH

Although the majority of patients with schizophrenia are not actually violent, an increased tendency toward violent behaviors is known to be associated with schizophrenia. There are several factors to consider...
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A Randomized Clinical Trial of Synbiotics in Irritable Bowel Syndrome: Dose-Dependent Effects on Gastrointestinal Symptoms and Fatigue

Lee SH, Cho DY, Lee SH, Han KS, Yang SW, Kim JH, Lee SH, Kim SM, Kim KN

BACKGROUND: This double-blind, randomized controlled design study aimed to assess the dose-dependent effects of synbiotics on gastrointestinal symptoms of and fatigue in irritable bowel syndrome (IBS). METHODS: Thirty subjects with IBS...
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Association of High-Risk Drinking with Metabolic Syndrome and Its Components in Elderly Korean Men: The Korean National Health and Nutrition Examination Survey 2010–2012

Kim JH, Ha JI, Park JM, Lee JS, Ahn AL, Oh EJ, Choi JK, Kweon HJ, Cho DY

BACKGROUND: Previous studies have examined the association between alcohol consumption and metabolic syndrome (MetS) in adults, but studies in the elderly are lacking. We examined the relationship between high-risk alcohol...
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Development of HLA-A, -B and -DR Typing Method Using Next-Generation Sequencing

Seo DH, Lee JM, Park MO, Lee HJ, Moon SY, Oh M, Kim SY, Lee SH, Hyeong KE, Hu HJ, Cho DY

BACKGROUND: Research on next-generation sequencing (NGS)-based HLA typing is active. To resolve the phase ambiguity and long turn-around-time of conventional high resolution HLA typing, this study developed a NGS-based high...
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Neonatal Patent Ductus Arteriosus Ligation Operations Performed by Adult Cardiac Surgeons

Chung YS, Cho DY, Kang H, Lee NM, Hong J

BACKGROUND: Patent ductus arteriosus (PDA) ligation is usually performed by congenital cardiac surgeons. However, due to the uneven distribution of congenital cardiac surgeons in South Korea, many institutions depend solely...
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Improved Gait Speed After Robot-Assisted Gait Training in Patients With Motor Incomplete Spinal Cord Injury: A Preliminary Study

Hwang S, Kim HR, Han ZA, Lee BS, Kim S, Shin H, Moon JG, Yang SP, Lim MH, Cho DY, Kim H, Lee HJ

OBJECTIVE: To evaluate the clinical features that could serve as predictive factors for improvement in gait speed after robotic treatment. METHODS: A total of 29 patients with motor incomplete spinal cord...
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Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis

Kim YN, Choe SR, Cho KH, Cho DY, Kang J, Park CG, Lee HY

Hippo/YAP signaling is implicated in tumorigenesis and progression of various cancers. By inhibiting a plethora signaling cascades, resveratrol has strong anti-tumorigenic and anti-metastatic activity. In the present study, we demonstrate...
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Post lumbar puncture headache: Case report of a serious adverse event in first-in-human study

Shin W, Kim MK, Kim J, Woo MH, Cho DY, Lim KS

A lumbar puncture can be used to measure the concentrations of drugs and/or pharmacodynamic biomarkers during clinical trials of central nervous system drugs. We report a case of a post...
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Double primary lung adenocarcinoma diagnosed by epidermal growth factor receptor mutation status

Kwon OJ, Lee MH, Kang SJ, Kim SG, Jeong IB, Jeong JY, Cha EJ, Cho DY, Kim YJ, Son JW

A nodular density was detected on a chest radiograph taken from a 57-year-old Korean woman who was visiting a hospital for a routine check. Chest computed tomography revealed a 4.8...
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Simultaneous chylothorax and chylous ascites

Jang TS, Jeong IB, Cho DY, Kang SJ, Kwon OJ

Chylothorax or chylous ascites are rare manifestations of liver cirrhosis. We report a rare case of simultaneous chylothorax and chylous ascites in a patient with hepatitis B virus-related liver cirrhosis....
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IgG4-Related Disease with lymphadenopathy Presenting as a Cervical lymph node enlargement

Choi YS, Kim S, Sohn JS, Hwang J, Chang T, Cho DY

During the course of evaluation and management of neck masses, consideration for Immunoglobulin G4-related disease (IgG4-RD) should be given. IgG4-RD is relatively a new growing entity of immune-mediated origin, characterized...
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The Effect of Xanthigen on the Expression of Brown Adipose Tissue Assessed by 18F-FDG PET

Kim KM, Kim SM, Cho DY, Park SJ, Joo NS

Brown adipose tissue (BAT) is related with energy expenditure, in contrary to fat-storing white adipose tissue. Recent studies have shown that cold exposure could be related with the expression of...
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Fibroblast Growth Factor Receptor 1 Overexpression Is Associated with Poor Survival in Patients with Resected Muscle Invasive Urothelial Carcinoma

Lim S, Koh MJ, Jeong HJ, Cho NH, Choi YD, Cho DY, Lee HY, Rha SY

PURPOSE: To examine the usefulness of various receptor tyrosine kinase expressions as prognostic markers and therapeutic targets in muscle invasive urothelial cancer (UC) patients. MATERIALS AND METHODS: We retrospectively analyzed the...
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Analysis of BRIP1 Variants among Korean Patients with BRCA1/2 Mutation-Negative High-Risk Breast Cancer

Kim H, Cho DY, Choi DH, Jung GH, Shin I, Park W, Huh SJ, Nam SJ, Lee JE, Gil WH, Kim SW

PURPOSE: The aim of the current study is to assess the spectrum of genetic variation in the BRIP1 gene among Korean high-risk breast cancer patients who tested negative for the...
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Spontaneous Retropharyngeal and Mediastinal Emphysema

Cho DY, Aaron GP, Shepard KG

A 14-year-old girl with no significant medical history presented at Emergency Department with sore throat and odynophagia after one episode of nonviolent coughing. She denied any respiratory distress, voice change,...
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Anti-tumor Immune Response after Cryoablation in Renal Cell Carcinoma Murine Model

Yeo JK, Cho DY, Park MG

PURPOSE: Cryoablation has been used successfully for the local treatment of renal cell carcinoma. Besides local destruction, Cryoablation has an immunogenic nature. In this study, we evaluated the anti-tumor immune...
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Controlling Legal Risk for Effective Hospital Management

Park HJ, Cho DY, Park YS, Kim SW, Park JH, Park NC

PURPOSE: To analyze the types of medical malpractice, medical errors, and medical disputes in a university hospital for the proposal of countermeasures that maximize the efficiency of hospital management, medical...
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