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Enhanced Efficacy of Immunization with a Foot-and-Mouth Disease Multi-Epitope Subunit Vaccine Using Mannan-Decorated Inulin Microparticles

Yoon SY, Kang SK, Lee HB, Oh SH, Kim WS, Li HS, Bok JD, Cho CS, Choi YJ

BACKGROUND: Despite the many advantages of recombinant subunit vaccines, they have critical weaknesses that include a low efficacy for promoting cellular and humoral immune responses against antigens because of their...
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Applications of Organoids for Tissue Engineering and Regenerative Medicine

Yoo JJ, Cho CS, Jo I

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Updates in Cartilage Tissue Regeneration

Im GI, Cho CS

No abstract available.
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Enhancement of antigen-specific humoral immune responses and protein solubility through conjugation of bacterial flagellin, Vibrio vulnificus FlaB, to the N-terminus of porcine epidemic diarrhea virus surface protein antigen S0

Oh SH, Kim Cho YS, Lee HB, Lee SM, Kim WS, Hong L, Cho CS, Choi YJ, Kang SK

Porcine epidemic diarrhea (PED) is a highly contagious enteric swine disease. The large economic impact of PED on the swine industry worldwide has made the development of an effective PED...
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Updates in molecular imaging techniques

Hyun H, Cho CS

No abstract available.
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Distinct Urinary Metabolic Profile in Rheumatoid Arthritis Patients: A Possible Link between Diet and Arthritis Phenotype

Koh JH, Park YJ, Lee S, Hong YS, Hong KS, Yoo SA, Cho CS, Kim WU

OBJECTIVE: We undertook this study to investigate the discriminant metabolites in urine from patients with established rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and from healthy individuals. METHODS: Urine samples were...
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Oral Immunization of FMDV Vaccine Using pH-Sensitive and Mucoadhesive Thiolated Cellulose Acetate Phthalate Microparticles

Lee HB, Yoon SY, Singh B, Oh SH, Cui L, Yan C, Kang SK, Choi YJ, Cho CS

Several barriers such as gastric pH, enzymatic degradation and rapid transit should be overcome to orally deliver antigens for taking up by epithelial microfold cells in Peyer's patches of small...
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Rapid onset of efficacy predicts response to therapy with certolizumab plus methotrexate in patients with active rheumatoid arthritis

Kang YM, Park YE, Park W, Choe JY, Cho CS, Shim SC, Bae SC, Suh CH, Cha HS, Koh EM, Song YW, Yoo B, Lee SS, Park MC, Lee SH, Arendt C, Koetse W, Lee SK

BACKGROUND/AIMS: The objective of this study was to determine the efficacy and safety of add-on therapy with certolizumab pegol (CZP) in active rheumatoid arthritis (RA) patients of a single ethnicity. METHODS:...
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Injectable Biomaterials in Plastic and Reconstructive Surgery: A Review of the Current Status

Cho KH, Uthaman S, Park IK, Cho CS

BACKGROUND: Injectable biomaterials have attracted increasing attention for volume restoration and tissue regeneration. The main aim of this review is to discuss the current status of the injectable biomaterials for...
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Injectable Hydrogels for Regenerative Medicine

Kim BS, Cho CS

No abstract available.
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MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis

Hong BK, You S, Yoo SA, Park D, Hwang D, Cho CS, Kim WU

Fibroblast-like synoviocytes (FLSs) constitute a major cell subset of rheumatoid arthritis (RA) synovia. Dysregulation of microRNAs (miRNAs) has been implicated in activation and proliferation of RA-FLSs. However, the functional association...
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Local Delivery of CTGF siRNA with Poly(sorbitol-co-PEI) Reduces Scar Contraction in Cutaneous Wound Healing

Cho KH, Singh B, Maharjan1 , Jang Y, Choi YJ, Cho CS

Healing process in scarring inevitably produces a considerable amount of non-organized dense collagen-rich matrix called scar thus impairing the native structure of skin. Connective tissue growth factor (CTGF) overexpression within...
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Combined Bifrontal Transcranial Direct Current Stimulation and Tailor-Made Notched Music Training in Chronic Tinnitus

Lee HY, Choi MS, Chang DS, Cho CS

BACKGROUND AND OBJECTIVES: We evaluated the short-term treatment outcomes of combined bifrontal transcranial direct current stimulation (tDCS) and tailor-made notched music training (TMNMT) in tinnitus patients. The associations of patient...
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Median and ulnar F-wave inversion as a supplementary criterion for diagnosis of carpal tunnel syndrome

Kim Y, Jang JH, Cho CS, Kim BJ

BACKGROUND: Median F-wave latencies are physiologically shorter than ulnar latencies, but they are often longer relative to ulnar latencies in carpal tunnel syndrome (CTS). This study aimed to investigate the...
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Drug- and Gene-eluting Stents for Preventing Coronary Restenosis

Lekshmi KM, Che HL, Cho CS, Park IK

Coronary artery disease (CAD) has been reported to be a major cause of death worldwide. Current treatment methods include atherectomy, coronary angioplasty (as a percutaneous coronary intervention), and coronary artery...
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Mutational Analysis of Extranodal NK/T-Cell Lymphoma Using Targeted Sequencing with a Comprehensive Cancer Panel

Choi S, Go JH, Kim EK, Lee H, Lee WM, Cho CS, Han K

Extranodal natural killer (NK)/T-cell lymphoma, nasal type (NKTCL), is a malignant disorder of cytotoxic lymphocytes of NK or T cells. It is an aggressive neoplasm with a very poor prognosis....
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Structural Variation of Alu Element and Human Disease

Kim S, Cho CS, Han K, Lee J

Transposable elements are one of major sources to cause genomic instability through various mechanisms including de novo insertion, insertion-mediated genomic deletion, and recombination-associated genomic deletion. Among them is Alu element...
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The First Case of Vestibulocochlear Neuritis in a Patient with Acquired Immunodeficiency Syndrome in Korea

Park HJ, Cho CS, Kim NM, Yun SA, Yoon HJ

The incidence of human immunodeficiency virus (HIV) infections continue to increase throughout the world. Although neurologic complications are frequent in individuals with HIV infection or acquired immunodeficiency syndrome (AIDS), vestibulocochlear...
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Gene Therapy for Bone Tissue Engineering

Kim YD, Pofali P, Park TE, Singh B, Cho K, Maharjan S, Dandekar P, Jain R, Choi YJ, Arote R, Cho CS

Gene therapy holds a great promise and has been extensively investigated to improve bone formation and regeneration therapies in bone tissue engineering. A variety of osteogenic genes can be delivered...
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Identification of novel urinary biomarkers for assessing disease activity and prognosis of rheumatoid arthritis

Park YJ, Yoo SA, Hwang D, Cho CS, Kim WU

To optimize treatment for rheumatoid arthritis (RA), it is ideal to monitor the disease activity on a daily basis because RA activity fluctuates over time. Urine can be collected routinely...
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