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Single Cell Transcriptomic Re-analysis of Immune Cells in Bronchoalveolar Lavage Fluids Reveals the Correlation of B Cell Characteristics and Disease Severity of Patients with SARS-CoV-2 Infection

Kim CW, Oh JE, Lee HK

The coronavirus disease 2019 (COVID-19) pandemic (severe acute respiratory syndrome coronavirus 2) is a global infectious disease with rapid spread. Some patients have severe symptoms and clinical signs caused by...
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Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A

Lee Y, Chae W, Yoon S, Chung JY, Cho JY

Cytochrome P450 (CYP) 3A enzymes, the most important phase 1 drug-metabolizing enzymes, are responsible for 50% of the metabolism of clinically used drugs. CYP3A activity varies widely among individuals, which...
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Clinical Characteristics of Campylobacter Enterocolitis in Korean Adults: A Retrospective Study at a Single Center

Yoo M, Chung SH, Park YS, Oh IH, Chae WY, Kim SH, Lee KY, Song CW, Son BK, Kim SH, Jo YK, Jung KH, Lee HY, Chae JD

Background/Aims: Although the diarrheal disease caused by Campylobacter bacteria has been continuously increasing in Korea, there has been limited study on the clinical aspects of Campylobacter enteritis in adults in...
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Development of an analytical method for the determination of dl-methylephedrine hydrochloride in porcine muscle using liquid chromatography-tandem mass spectrometry

Chae WS, Kim S, Lee HJ

This study examined the residue of dl-methylephedrine hydrochloride (MEP) on the muscle of pigs administered orally with MEP 12 g/ton feed for seven consecutive days. Twenty healthy cross swine were...
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Feasibility and efficacy of coil embolization for middle cerebral artery aneurysms

Choi JY, Choi CH, Ko JK, Lee JI, Huh CW, Lee TH

BACKGROUND: The anatomy of middle cerebral artery (MCA) aneurysms has been noted to be unfavorable for endovascular treatment. The purpose of this study was to assess the feasibility and efficacy...
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An Estimation of Supply and Demand for Primary Healthcare Nursing Workforce in the North Korean Region after Korean Reunification

Kim J, Jung Y, Choi H, Chae SM, Chung CW, Chung N, Piao M

PURPOSE: This study was done to estimate supply and demand for nursing workforce to provide community-based primary healthcare in the North Korean region to cost-efficiently narrow the health gap between...
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Clinical Characteristics of Non-Amnestic Mild Cognitive Impairment: A Single-Center Experience

Oh E, Shin CW, Kim BJ, Hwang KJ, Heo SH, Ahn TB, Chang DI, Yoon SS, Park KC, Lee JS

BACKGROUND: To evaluate the clinical characteristics of patients with non-amnestic mild cognitive impairment (naMCI) in a memory disorder clinic at a single center. METHODS: A retrospective study was conducted involving 312...
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Nonmotor and Dopamine Transporter Change in REM Sleep Behavior Disorder by Olfactory Impairment

Lee JY, Yoon EJ, Kim YK, Shin CW, Nam H, Jeong JM, Kim HJ, Jeon B

OBJECTIVE: It is unclear whether the decline in dopamine transporters (DAT) differs among idiopathic rapid eye movement sleep behavior disorder (iRBD) patients with different levels of olfactory impairment. This study...
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Conditions for the disinfectant efficacy test under subzero temperatures

Chae WS, Jeong W, Lee HJ

To establish appropriate conditions for a disinfectant efficacy test at subzero temperatures, this study examined mixtures of frozen foot-and-mouth disease virus or avian influenza virus solutions and disinfectant diluents at...
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Effect of Spine-Pelvis Relationship in Total Hip Arthroplasty

Lee SH, Lim CW, Choi KY, Jo S

When spine-pelvic motion is normally coordinated, the pelvis may tilt posteriorly and acetabular anteversion may increase as the patient's position changes from standing to sitting; this scenario allows for improved...
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Survival of in-hospital cardiac arrest patients before and after the implementation of the act on decisions on life-sustaining treatment: the well-dying law

Jeong CW, Lee MJ, Lim SH, Yang HM, Lim HS, Kim HH, Min YG, Kim M, Chae MK

OBJECTIVE: The act on decisions on life-sustaining treatment, the well-dying law (WDL), has been implemented in Korea since February of 2018 so that a patient may die with dignity in...
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The Association between Social Contacts and Depressive Symptoms among Elderly Koreans

Yang J, Park EC, Lee SA, Lee JE, Choi DW, Chae W, Jang SI

OBJECTIVE: South Korea has an increasing aging population; thus, the management of depressive symptoms in elderly individuals is important. In this population, fewer social contacts might be a risk factor...
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Postoperative Chylothorax: the Use of Dynamic Magnetic Resonance Lymphangiography and Thoracic Duct Embolization

Lee CW, Koo HJ, Shin JH, Kim MY, Yang DH

Dynamic enhanced magnetic resonance lymphangiography can be used to provide anatomic and dynamic information for various lymphatic diseases, including thoracic duct injury, and can also help to guide the thoracic...
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Coexistence of Intracranial Squamous Cell Carcinoma and Epidermoid Cyst: a Case with Consecutive Imaging Findings

Lee CW, Park JE, Lee JH, Kim HS, Kim SJ

In contrast to well-known imaging findings of intracranial epidermoid cysts on magnetic resonance imaging, those of intracranial squamous cell carcinoma (SqCC) are relatively unknown. We present a case of coexistence...
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Endosaccular Treatment of Very Large and Giant Intracranial Aneurysms with Parent Artery Preservation: Single Center Experience with Long Term Follow-up

Huh CW, Lee JI, Choi CH, Lee TH, Choi JY, Ko JK

OBJECTIVE: Very large (20–25 mm) and giant (≥25 mm) intracranial aneurysms have an extremely poor natural course, and treatment of these aneurysms remains a challenge for endovascular and surgical strategies....
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Amantadine and the Risk of Dyskinesia in Patients with Early Parkinson's Disease: An Open-Label, Pragmatic Trial

Kim A, Kim YE, Yun JY, Kim HJ, Yang HJ, Lee WW, Shin CW, Park H, Jung YJ, Kim A, Kim Y, Jang M, Jeon B

OBJECTIVE: We examined whether amantadine can prevent the development of dyskinesia. METHODS: Patients with drug-naïve Parkinson's disease (PD), younger than 70 years of age and in the early stage of PD...
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Pregnant Women's Labor Progress, Childbirth Outcome, and Childbirth Satisfaction according to the Presence or Absence of Labor Induction

Jeong YA, Chung CW

PURPOSE: To provide accurate information on induced labor and find strategies to enhance women's childbirth satisfaction. METHODS: Participants were pregnant women expected to have normal vaginal delivery. A total of 113...
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Position Value for Relative Comparison of Healthcare Status of Korea among Organization for Economic Cooperation and Development Countries, 2015

Chae W, Lee SA, Park EC

This study aims to evaluate the status of Korean healthcare among Organization for Economic Cooperation and Development countries and to monitor the trend of health care status since 2000. The...
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Effects of the Trunk Maintenance Repositioning Method on Keeping a 30° Side-Lying Position, Comfort, and Skin Condition

Lee CW, Yi YH

PURPOSE: This study was performed to evaluate the effects of a prolonged a 30°side-lying position on comfort and skin condition by applying the trunk maintenance repositioning method, which can keep...
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Morphological and Molecular Characterization of Toxocara tanuki (Nematoda: Ascaridae) from Korean Raccoon Dog, Nyctereutes procyonoides koreensis

Alexander , Lim CW, Kim B, Hong EJ, Kim HC, Park BK

Present study was performed to describe the morphological and molecular characterization of Toxocara tanuki (Nematoda: Ascaridae) from Korean raccoon dog, Nyctereutes procyonoides koreensis, naturally infected in the Republic of Korea...
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