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Identification of 8-Digit HLA-A, -B, -C, and -DRB1 Allele and Haplotype Frequencies in Koreans Using the One Lambda AllType Next-Generation Sequencing Kit

Choe W, Chae JD, Yang JJ, Hwang SH, Choi SE, Oh HB

Background: Recent studies have successfully implemented next-generation sequencing (NGS) in HLA typing. We performed HLA NGS in a Korean population to estimate HLA-A, -B, -C, and -DRB1 allele and haplotype...
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Osteomyelitis Caused by Hypervirulent Klebsiella pneumoniae: The First Korean Case With Family Spread

Lee CH, Chae JD, Choe W, Lee HY, Sohn YH, Ihm C, Jeong JH

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Medication Use Evaluation of Denosumab in Postmenopausal Women with Osteoporosis or Osteopenia

Lim SH, Jung WJ, Chae Jw, Kang C, Yun Hy

Background: The indication of denosumab for osteoporosis was expanded from second-line to first-line therapy in 2019. The aim of this study was to evaluate the efficacy of denosumab as both...
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KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

Lee JH, Seo HW, Ryu JY, Lim CJ, Yi KY, Oh KS, Lee BH

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of...
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Strategies for Reducing Mental Disorder Treatment Gap in Korea

Kim J, Chae JH

The treatment gap can be defined as the difference between the proportion of people who have the disease and the proportion of those who receive proper treatment. The mental disorder...
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Morphological and Molecular Characterization of Toxocara apodemi (Nematoda: Ascarididae) from Striped Field Mice, Apodemus agrarius, in Korea

Kim HC, Hong EJ, Ryu SY, Park J, Cho JG, Yu DH, Chae JS, Choi KS, Park BK

Adult ascarid worms from the field mice, Apodemus agrarius, were observed with a light and scanning electron microscope, and molecularly analized with 18S rRNA gene. In the scanning electron microscope,...
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Short Course and Early Switch of Vigabatrin for Infantile spasms

Ryu HW, Kim H, Lim BC, Hwang H, Chae JH, Choi JE, Kim KJ

Purpose: Vigabatrin has proven efficacy in the treatment of infantile spasms, but it carries the risk of irreversible visual field constriction. The incidence of vigabatrin-induced visual field constriction seems to...
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Attachment Style, Complicated Grief and Post-Traumatic Growth in Traumatic Loss: The Role of Intrusive and Deliberate Rumination

Huh HJ, Kim KH, Lee HK, Chae JH

Objective The present study examines the effects of attachment styles on the grief response and the indirect effect of rumination in parents who lost a child in the Sewol Ferry...
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Clinical Spectrum of Myelin Oligodendrocyte Glycoprotein-Immunoglobulin G-Associated Disease in Korean Children

Yoo IH, Kim W, Shim Y, Choi SA, Kim SY, Kim H, Lim BC, Hwang H, Choi J, Kim KJ, Kim Y, Hyun JW, Kim SH, Choi K, Kim HJ, Chae JH

Background and Purpose: The myelin oligodendrocyte glycoprotein (MOG) antibody is detected at a high rate in childhood acquired demyelinating syndrome (ADS). This study aimed to determine the diagnostic value of...
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Shprintzen–Goldberg syndrome with a novel missense mutation of SKI in a 6-month-old boy

Jeon MJ, Park SG, Kim MJ, Lim BC, Kim KJ, Chae JH, Kim SY

The Shprintzen–Goldberg syndrome (SGS) is an extremely rare genetic disorder caused by heterozygous variant in SKI . SGS is characterized by neurodevelopmental impairment with skeletal anomaly. Recognition of SGS is...
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Implications of Price Setting Strategies for New Health Technologies from Five Countries

Chung Sh, Kwon O, Choi Y, Moon K, Chae J, Lee R

This study aims to compare the experience of selected countries in operating separate payment system for new healthcare technology and to find implications for price setting in Korea. We analyzed...
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Relationship between Clinical Features of Diabetic Retinopathy and Systemic Factors in Patients with Newly Diagnosed Type II Diabetes Mellitus

Hwang H, Kim JY, Oh TK, Chae JB, Kim DY

Background: We investigated the relationship between clinical features of diabetic retinopathy (DR) and systemic factors in patients with newly diagnosed type II diabetes mellitus (T2DM). Methods: Retrospective review of newly diagnosed...
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Assessment of bone density changes following two-jaw surgery using multidetector computed tomography: A pilot study

Lee Y, Park JH, Chang NY, Lee MY, Kim BC, Seo HY, Mangal U, Chae JM

Objective: The aim of this retrospective study was to evaluate the pre- and postsurgical bone densities at alveolar and extra-alveolar sites following twojaw orthognathic surgery. Methods: The sample consisted of...
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Clinical Characteristics of Campylobacter Enterocolitis in Korean Adults: A Retrospective Study at a Single Center

Yoo M, Chung SH, Park YS, Oh IH, Chae WY, Kim SH, Lee KY, Song CW, Son BK, Kim SH, Jo YK, Jung KH, Lee HY, Chae JD

Background/Aims: Although the diarrheal disease caused by Campylobacter bacteria has been continuously increasing in Korea, there has been limited study on the clinical aspects of Campylobacter enteritis in adults in...
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Prevalence and Predictors of Polypharmacy among Elderly Outpatients in a Public Hospital

Koo HJ, Kim MJ, Park H, Chae J, Kim J, Park KH, Kim M

Background: Polypharmacy, the use of multiple drugs, is a growing concern in older adults. It has been reported that the prevalence of polypharmacy in elderly patients is higher in Korea...
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A Familial Case of Childhood Ataxia with Leukodystrophy Due to Novel POLR1C Mutations

Han JY, Kim SY, Cheon JE, Choi M, Lee JS, Chae JH

No abstract available.
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Korean Translation and Linguistic Validation of Urgency and Overactive Bladder Questionnaires

Kim SE, Lee HS, Lee HN, Lee SY, Choo MS, Park MG, Chae JY, Oh SJ, Cho SY

Purpose: Given the importance of evaluating the severity of overactive bladder (OAB) symptoms and outcomes after treatment, several questionnaires have been developed to evaluate OAB patients. However, only limited questionnaires...
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Clinical profiles of patients with surgically resected pheochromocytoma and paraganglioma

Lee SH, Park JH, Lee JY, Lee SR, Rhee KS, Chae JK, Kim WH, Sul JY, Oh JK, Kwon HJ, Lee JH, Seong IW

Background/Aims: Pheochromocytoma and paraganglioma (PPGL) are catecholamine-producing tumors that can cause blood pressure (BP) elevation and cardiovascular complications. Clinical presentation of these tumors may be changed through widespread use of...
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High Behavioral Inhibition System/Behavioral Activation System Sensitivity, Childhood Emotional Neglect and Their Interaction as Possible Related Factors for Adult Attachment Style in Depression

Huh HJ, Jeong BR, Hwang JH, Chae JH

Objective Individual differences in attachment insecurity are important in a broad range of mental health problems. However, few empirical studies have examined the clinical factors that contribute to individual differences...
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Clopidogrel versus Aspirin after Dual Antiplatelet Therapy in Acute Myocardial Infarction Patients Undergoing Drug-Eluting Stenting

Sim DS, Jeong MH, Kim HS, Gwon HC, Seung KB, Rha SW, Chae SC, Kim CJ, Cha KS, Park JS, Yoon JH, Chae JK, Joo SJ, Choi DJ, Hur SH, Seong IW, Cho MC, Kim DI, Oh SK, Ahn TH, Hwang JY, on behalf of the KAMIR-NIH registry investigators

BACKGROUND AND OBJECTIVES: There is a paucity of data regarding the benefit of clopidogrel monotherapy after dual antiplatelet therapy (DAPT) in patients treated with drug-eluting stents (DES). This study compared...
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