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A Study on the Relationship between Sleep Quality and Cognitive Function in Community Elderly

Oh YK, Kim BJ, Park CS, Lee CS, Cha BS, Lee SJ, Lee DY, Seo JY, Lee YJ, Choi JW, Lee JH, Lee YJ

Objectives: Sleep disturbance in the elderly is associated with cognitive decline. Sleep quality is known to deteriorate with age, and prospective studies seldom have examined the relationship between sleep quality...
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Association between Non-Alcoholic Steatohepatitis and Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus

Lee H, Kim G, Choi YJ, Huh BW, Lee BW, Kang ES, Cha BS, Lee EJ, Lee Yh, Huh KB

Background: Impaired diastolic heart function has been observed in persons with non-alcoholic fatty liver disease (NAFLD) and/or with type 2 diabetes mellitus (T2DM). However, it is unclear whether NAFLD fibrotic...
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Association Between Serum Bilirubin and the Progression of Carotid Atherosclerosis in Type 2 Diabetes

Lee I, Lee HH, Cho Y, Choi YJ, Huh BW, Lee BW, Kang ES, Park SW, Cha BS, Lee EJ, Lee YH, Huh KB

OBJECTIVE: This study investigated whether serum bilirubin levels can predict the progression of carotid atherosclerosis in individuals with type 2 diabetes mellitus (T2DM). METHODS: This observational study included 1,381 subjects with...
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Current Management of Type 2 Diabetes Mellitus in Primary Care Clinics in Korea

Seo DH, Kang S, Lee YH, Ha JY, Park JS, Lee BW, Kang ES, Ahn CW, Cha BS

BACKGROUND: This study investigated the overall status of diabetes control and screening for diabetic microvascular complications in patients with type 2 diabetes mellitus attending primary care clinics in Korea. METHODS: In...
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Efficacy and Safety of Voglibose Plus Metformin in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Oh TJ, Yu JM, Min KW, Son HS, Lee MK, Yoon KH, Song YD, Park JY, Jeong IK, Cha BS, Kim YS, Baik SH, Kim IJ, Kim DM, Kim SR, Lee KW, Park JH, Lee IK, Park TS, Choi SH, Park SW

BACKGROUND: Combination of metformin to reduce the fasting plasma glucose level and an α-glucosidase inhibitor to decrease the postprandial glucose level is expected to generate a complementary effect. We compared...
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Predictive Factors for Efficacy of AST-120 Treatment in Diabetic Nephropathy: a Prospective Single-Arm, Open-Label, Multi-Center Study

Hwang YC, Kim SW, Hur KY, Cha BS, Kim IJ, Park TS, Baik SH, Yoon KH, Lee KW, Lee IK, Lee MK

BACKGROUND: Removal of uremic toxins such as indoxyl sulfate by AST-120 is known to improve renal function and delay the initiation of dialysis in patients with advanced chronic kidney disease....
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Predictors of the Therapeutic Efficacy and Consideration of the Best Combination Therapy of Sodium-Glucose Co-transporter 2 Inhibitors

Lee JY, Cho Y, Lee M, Kim YJ, Lee YH, Lee BW, Cha BS, Kang ES

BACKGROUND: We investigated the predictive markers for the therapeutic efficacy and the best combination of sodium-glucose co-transporter 2 (SGLT2) inhibitors (empagliflozin, dapagliflozin, and ipragliflozin) therapy in patients with type 2...
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Nonalcoholic Fatty Liver Disease and Diabetes: Part II: Treatment

Kim KS, Lee BW, Kim YJ, Lee DH, Cha BS, Park CY

Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders that are often comorbid conditions. Among many proposed treatments, weight reduction is the only approved option for NAFLD to...
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Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis

Lee YH, Cho Y, Lee BW, Park CY, Lee DH, Cha BS, Rhee EJ

Nonalcoholic fatty liver disease (NAFLD) and diabetes are common metabolic disorders whose prevalence rates are expected to rise worldwide, corresponding to aging and increasingly obese populations. Compared to the general...
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Corrigenda: Table Correction. Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis

Lee YH, Cho Y, Lee BW, Park CY, Lee DH, Cha BS, Rhee EJ

In this article, the description of one equation named “NAFLD liver fat score” in the Table 3 was miswritten.
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Effects of Combination Therapy of Statin and Thiazolidinedione on Vascular Inflammation

Lee JY, Cha BS

No abstract available.
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Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis

Hong N, Lee YH, Tsujita K, Gonzalez J, Kramer CM, Kovarnik T, Kouvelos G, Suzuki H, Han K, Lee CJ, Park SH, Lee BW, Cha BS, Kang ES

BACKGROUND: Ezetimibe-statin combination therapy has been found to reduce low density lipoprotein cholesterol levels and the risk of major adverse cardiovascular events (MACEs) in large trials. We sought to examine...
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Effects of Serum Albumin, Calcium Levels, Cancer Stage and Performance Status on Weight Loss in Parathyroid Hormone-Related Peptide Positive or Negative Patients with Cancer

Lee JY, Hong N, Kim HR, Lee BW, Kang ES, Cha BS, Lee YH

BACKGROUND: A recent animal study showed that parathyroid hormone-related peptide (PTHrP) is associated with cancer cachexia by promoting adipose tissue browning, and we previously demonstrated that PTHrP predicts weight loss...
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Comparison between Atorvastatin and Rosuvastatin in Renal Function Decline among Patients with Diabetes

Han E, Kim G, Lee JY, Lee YH, Kim BS, Lee BW, Cha BS, Kang ES

BACKGROUND: Although the beneficial effects of statin treatment in dyslipidemia and atherosclerosis have been well studied, there is limited information regarding the renal effects of statins in diabetic nephropathy. We...
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Addition of Ipragliflozin to Metformin Treatment in Korean Patients with Type 2 Diabetes Mellitus: Subgroup Analysis of a Phase 3 Trial

Min KW, Ku BJ, Lee JH, Kim MS, Ahn KJ, Lee MK, Kokubo S, Yoshida S, Cho HJ, Cha BS

BACKGROUND: This is a subgroup analysis of Korean patients from a phase 3 clinical trial investigating the efficacy and safety of ipragliflozin in patients with type 2 diabetes mellitus inadequately...
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Association between Metformin Use and Risk of Lactic Acidosis or Elevated Lactate Concentration in Type 2 Diabetes

Lee EY, Hwang S, Lee YH, Lee SH, Lee YM, Kang HP, Han E, Lee W, Lee BW, Kang ES, Cha BS, Lee HC

PURPOSE: Metformin can reduce diabetes-related complications and mortality. However, its use is limited because of potential lactic acidosis-associated adverse effects, particularly in renal impairment patients. We aimed to investigate the...
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Morning Spot Urine Glucose-to-Creatinine Ratios Predict Overnight Urinary Glucose Excretion in Patients With Type 2 Diabetes

Kim SR, Lee YH, Lee SG, Lee SH, Kang ES, Cha BS, Lee HC, Kim JH, Lee BW

BACKGROUND: With the advent of sodium glucose co-transporter 2 inhibitors to control glucose and treat diabetes, laboratory data aided by either timed or spot glucose levels in the urine could...
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A Case of Autoantibody-Positive Ketosis-Prone Diabetes Mellitus

Yoon B, Kim G, Bae JH, Yun YJ, Lee YH, Lee BW, Ahn CW, Cha BS, Lee HC, Kang ES

Ketosis-prone diabetes mellitus (KPD), which is an atypical type of diabetic mellitus with severe β cell dysfunction, is accompanied by ketosis or ketoacidosis without specific preceding factors at diagnosis. KPD...
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Fellows' perception of fellowship training and overarching issues

Yang EB, Kim SW, Kim JJ, Eun BL, Oh ST, Cha BS, Lee SK, Chung HS, Kim DI

Patient expectations for specialized medical care have spawned fellowship programs that require additional subspecialty training after residency training completion. The present study assessed the curricula and training environment adequacy of...
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Characteristics Predictive for a Successful Switch from Insulin Analogue Therapy to Oral Hypoglycemic Agents in Patients with Type 2 Diabetes

Kim G, Lee YH, Kang ES, Cha BS, Lee HC, Lee BW

PURPOSE: The objective of this study was to investigate clinical and laboratory parameters that could predict which patients could maintain adequate glycemic control after switching from initial insulin therapy to...
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