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Qualification and application of liquid chromatography-quadrupole time-offlight mass spectrometric method for the determination of carisbamate in rat plasma and prediction of its human pharmacokinetics using physiologically based pharmacokinetic modeling

Lee Bi, Lim Jh, Park MH, Shin SH, Byeon JJ, Choi Jm, Park Sj, Park Mj, Park Y, Shin YG

Carisbamate is an antiepileptic drug and it also has broad neuroprotective activity and anticonvulsant reaction. In this study, a liquid chromatography-quadrupole time-of-flight mass spectrometric (LC-qTOF-MS) method was developed and applied...
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Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin

Park MH, Shin SH, Byeon JJ, Lee GH, Yu BY, Shin YG

Over the last decade, physiologically based pharmacokinetics (PBPK) application has been extended significantly not only to predicting preclinical/human PK but also to evaluating the drug-drug interaction (DDI) liability at the...
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Alexithymia and non ulcer dyspepsia

Ko SM, Byeon JJ, Lee KH

  • KMID: 2295043
  • J Korean Acad Fam Med.
  • 2001 Aug;22(8):1204-1213.
BACKGROUND: The pathophysiology of non ulcer dyspepsia remains unknown. But Several related factors have been investigated and psychologic factor is one of the possible mechanism. Alexithymia was introduced to explain...
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Preferred place of death of elderly women in seoul

Choi JH, Byeon JJ, Lee S, Han SH

  • KMID: 2295086
  • J Korean Acad Fam Med.
  • 2001 Jun;22(6):939-945.
BACKGROUND: The present it is getting to be on aged society there is increasing that hospital has higher rate for place of death than home. Because we can expect that...
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Evaluation of Residency Program Using the Result of in-training Examination

Song YM, Hwang IH, Byeon JJ

  • KMID: 2306881
  • Korean J Med Educ.
  • 2001 Nov;13(2):259-267.
BACKGROUND: There has been widespread use of in-training examination for the evaluation of clinical competence of residents. The result of in-training examination seems to be helpful for improving the quality...
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The effectiveness of a letter reminder on the compliance with periodic follow-up examination in chronic HBsAg-positive patients

Choi CH, Song YM, Oh JS, Byeon JJ

  • KMID: 2295181
  • J Korean Acad Fam Med.
  • 2000 Sep;21(9):1188-1198.
BACKGROUND: For Chronic HBsAg-positive patients are a well-known high risk group of primary liver cancer necessitating periodic follow-up examination. This study was performed to evaluate the effectiveness of a reminding...
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Antibiotics prescription pattern of family practitioners for respiratory tract infections

Eo KS, Byeon JJ, Shin HC, Kim CH, Lee JH, Choi YS, Roh YK

  • KMID: 2295204
  • J Korean Acad Fam Med.
  • 2000 Jul;21(7):901-913.
BACKGROUND: Antibiotics are often indiscriminately prescribed for respiratory tract infections. This study was conducted to describe the prescription pattern of family physicians for respiratory tract infections. METHODS: In each clinic...
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Seasonal variation of blood pressure in patients with hypertension

Byeon JJ, Kim DJ

  • KMID: 2295292
  • J Korean Acad Fam Med.
  • 1999 Dec;20(12):1770-1777.
BACKGROUND: Seasonal variation of blood pressure (BP) is well documented. It means that season should be considered in diagnosis and treatment of hypertension. This study was done to evaluate seasonal...
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Cognition and performance rate for adult immunization among urban general population

Ko SH, Song YM, Byeon JJ

  • KMID: 2295398
  • J Korean Acad Fam Med.
  • 1998 Oct;19(10):870-880.
BACKGROUND: Although adult immunization is as important as childhood immunization, is being inadequately performed. However, previous studies concerning adult immunization could not be sufficiently evaluate because studies were restricted to...
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Inappropriate Drug Prescription for the Patients Who Visit Two or More Doctors

Byeon JJ, Han TH

  • KMID: 2056331
  • J Korean Acad Fam Med.
  • 1997 Sep;18(9):927-935.
BACKGROUND: If two or more doctors prescribe for one patient, each doctor must be careful to minimize the number of drugs and the frequency of admistration, and also be careful...
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The Relationship Between Cholesterol Level and Mortality in Korean Women

Song YM, Sung JH, Byeon JJ, Kim JS, Park OY

  • KMID: 2304058
  • Korean J Epidemiol.
  • 1997 Dec;19(2):131-146.
BACKGROUND: There were many efforts to evaluate the relationship between cholesterol and mortality. But almost all of them have been performed on male western people who have higher mean cholesterol...
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Prescription of Digestive System Drugs to the Patients with No Digestive Symptoms

Byeon JJ

  • KMID: 2295565
  • J Korean Acad Fam Med.
  • 1997 Jan;18(1):78-84.
BACKGROUND: In Korea, doctors are tend to prescribe digestive system drugs to the patients who have no digestive symptoms. The purpose of this study was to describe the prescription tendency...
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A study on injection preference of patients in a rural area

Byeon JJ, Choi YI, Joo YH, Park YU, Yoo TW, Huh BY

  • KMID: 1699107
  • J Korean Acad Fam Med.
  • 1991 Jul;12(7):1-10.
No abstract available.
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