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Gemigliptin Inhibits Interleukin-1β–Induced Endothelial-Mesenchymal Transition via Canonical-Bone Morphogenetic Protein Pathway

Hong OK, Lee SS, Yoo SJ, Lee MK, Kim MK, Baek KH, Song KH, Kwon HS

Background: Endothelial-to-mesenchymal transition (EndMT) contributes to inflammatory conditions inducing conversion of endothelial cells (ECs) into activated fibroblasts, promoting fibrotic diseases. Pro-inflammatory cytokine is the most potent inducer of EndMT. We...
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Consistency of the Glycation Gap with the Hemoglobin Glycation Index Derived from a Continuous Glucose Monitoring System

Joung HN, Kwon HS, Baek KH, Song KH, Kim MK

Background: Discordances between glycated hemoglobin (HbA1c) levels and glycemic control are common in clinical practice. We aimed to investigate the consistency of the glycation gap with the hemoglobin glycation index...
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Effect of Spiral Elastic Band on Gait Function in Patients with Chronic Stroke

Baek KH, Lim HW

PURPOSE: This study examined the effects of a spiral elastic band for the walking function on patients with chronic stroke. METHODS: Twenty one chronic stroke patients were recruited and divided randomly...
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Pathogenetic factors involved in recurrent pregnancy loss from multiple aspects

Pei CZ, Kim YJ, Baek KH

Recurrent pregnancy loss (RPL) is a common complication in obstetrics, affecting about 5% of women of childbearing age. An increase in the number of abortions results in escalation in the...
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A Review of Improvements for Providing Safe and Secure Environments for Medical Treatment

Choe AR, Kim SE, Baek KH

On December 31, 2018, an incident occurred where a doctor was attacked and killed by a patient carrying a lethal weapon in the outpatients' clinic of the psychiatric department of...
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Comparison of Natural Course between Thyroid Cancer Nodules and Thyroid Benign Nodules

Yun KJ, Ha J, Kim MH, Seo YY, Kim MK, Kwon HS, Song KH, Kang MI, Baek KH

BACKGROUND: The natural course of thyroid cancer nodules and benign nodules is different. This study was to compare the changes in size between thyroid cancer nodules and thyroid benign nodules....
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The Analysis of Studies Related to the Learning Methods of Biological Nursing Subjects in Korea

Park JM, Baek KH

PURPOSE: The purpose of this study was to analyze the current status of studies related to the learning methods of biological nursing subjects in Korea. METHODS: Five databases (KoreaMed, KMbase, NDSL,...
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The Association between Pancreatic Steatosis and Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients

Jeong JS, Kim MK, Han KD, Hong OK, Baek KH, Song KH, Chung DJ, Lee JM, Kwon HS

BACKGROUND: Whether pancreatic steatosis has a local or systemic effect, like ectopic fat of other major organs, remains unknown. Data on the influence of pancreatic steatosis on microvascular complication are...
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Hypertension and Neuropsychiatric Symptoms in Patients with Drug-Naïve Alzheimer's Disease

Hwang I, Baek KH, Han JH, Ha SW, Yang Y

BACKGROUND AND PURPOSE: Neuropsychiatric symptoms (NPS) such as anxiety, depression, and delusions affect up to 90% of all patients with Alzheimer's disease (AD). NPS is associated with significant caregiver burden...
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Biochemical Markers as Predictors of In-Hospital Mortality in Patients with Severe Trauma: A Retrospective Cohort Study

Jang HN, Park HO, Yang TW, Yang JH, Kim SH, Moon SH, Byun JH, Lee CE, Kim JW, Kang DH, Baek KH

BACKGROUND: Initial evaluation of injury severity in trauma patients is an important and challenging task. We aimed to assess whether easily measurable biochemical parameters (hemoglobin, pH, and prothrombin time/international normalized...
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The Safety and Decision Making of Instrumented Surgery in Infectious Spondylitis

Baek KH, Lee YS, Kang DH, Lee CH, Hwang SH, Park IS

OBJECTIVE: Infectious spondylitis is mostly managed by appropriate antibiotic treatment options, and some patients may require surgical interventions. However, surgical interventions that use spinal instrumentation to correct the mechanical instability...
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Effects of Small Dense LDL in Diabetic Nephropathy in Females with Type 2 Diabetes Mellitus

Ryu S, Kim Y, Kim MK, Kwon HS, Baek KH, Song KH, Yun KJ

OBJECTIVE: This study investigated the association between small-dense low-density lipoprotein (sdLDL) and diabetic nephropathy (DN) in type 2 diabetic patients. METHODS: A total of 172 type 2 diabetic patients (95 men...
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Systematic Analysis of the Anticancer Agent Taxol-Producing Capacity in Colletotrichum Species and Use of the Species for Taxol Production

Choi J, Park JG, Ali MS, Choi SJ, Baek KH

Paclitaxel (taxol) has long been used as a potent anticancer agent for the treatment of many cancers. Ever since the fungal species Taxomyces andreanae was first shown to produce taxol...
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Lipopolysaccharide-binding protein plasma levels as a biomarker of obesity-related insulin resistance in adolescents

Kim KE, Cho YS, Baek KS, Li L, Baek KH, Kim JH, Kim HS, Sheen YH

PURPOSE: Lipopolysaccharide-binding protein (LBP) is a 65-kDa acute phase protein, derived from the liver, which is present in high concentrations in plasma. Data regarding the association between circulating plasma LBP...
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High glucose and palmitate increases bone morphogenic protein 4 expression in human endothelial cells

Hong OK, Yoo SJ, Son JW, Kim MK, Baek KH, Song KH, Cha BY, Jo H, Kwon HS

Here, we investigated whether hyperglycemia and/or free fatty acids (palmitate, PAL) aff ect the expression level of bone morphogenic protein 4 (BMP4), a proatherogenic marker, in endothelial cells and the...
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A Case of Bilateral Diffuse Diabetic Muscle Infarction of the Thighs in a Patient with Good Glucose Control

Lee HJ, Kim HJ, Hwang SY, Kim MK, Kwon HS, Baek KH, Song KH, Yun KJ

Diabetic muscle infarction (DMI) is a rare condition that usually occurs in diabetic patients who have longstanding microvascular complication. The typical presentation is a painful swelling with abrupt onset in...
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Risk Factors for the Development and Progression of Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus and Advanced Diabetic Retinopathy

Yun KJ, Kim HJ, Kim MK, Kwon HS, Baek KH, Roh YJ, Song KH

BACKGROUND: Some patients with type 2 diabetes mellitus (T2DM) do not develop diabetic kidney disease (DKD) despite the presence of advanced diabetic retinopathy (DR). We aimed to investigate the presence...
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Usefulness of Dipstick Test for Vitreous Glucose in Autopsy Practice

Lee K, Koo HN, Kim TG, Park JY, Baek KH, Choi SG, Choi CH, Aum N, Lee NW, Choi BH

The concentration of glucose in the vitreous humor serves as an important diagnostic marker for diabetic mellitus in post-mortem examinations, as the vitreous humor can be easily collected and the...
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A Viewpoint on Treatment of Traumatic Bilateral Basal Ganglia Hemorrhage in a Child: Case Report

Baek KH, Lee CH, Kim SK, Park H, Kang DH, Hwang SH

Traumatic basal ganglia hemorrhage (TBGH) is a rare presentation of head injuries. Bilateral lesions are extremely rare. The pathophysiologic mechanism of bilateral TBGH seems to be the same as diffuse...
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Efficacy of a Once-Monthly Pill Containing Ibandronate and Cholecalciferol on the Levels of 25-Hydroxyvitamin D and Bone Markers in Postmenopausal Women with Osteoporosis

Cho IJ, Chung HY, Kim SW, Lee JW, Lee TW, Kim HS, Kim SG, Choi HS, Choi SH, Shin CS, Oh KW, Min YK, Koh JM, Rhee Y, Byun DW, Chung YS, Park JH, Chung DJ, Shong M, Hong EG, Lee CB, Baek KH, Kang MI

BACKGROUND: The present study evaluated the efficacy of a combination of ibandronate and cholecalciferol on the restoration of the levels of 25-hydroxyvitamin D (25[OH]D) and various bone markers in postmenopausal...
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