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Cholangitis Caused by Hereditary Spherocytosis in Adulthood Treated by Endoscopic Retrograde Cholangiopancreatography

Park TY, Jun JH, Kang H, Doh YS, Jang JW, Baek IH, Jung SH

Hereditary spherocytosis is a disease caused by deficiency of erythrocyte lipid membrane protein. Hereditary spherocytosis shows hemolysis of erythrocyte, and it leads to anemia, jaundice by elevation of indirect bilirubin....
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A Comparative Study on the Clinical Efficacy and Safety between Combination Therapy with CDK 4/6 Inhibitor and AI Versus AI Monotherapy in HR+/HER type2- Advanced Breast Cancer: Updated Meta-analysis

Kim MJ, Kim K, Cho M, Sohn K, Baek Ih

Objective: The aim of the study was to perform a meta-analysis of randomized clinical trials to compare the clinical efficacy and safety between combination of cyclin-dependent kinase (CDK) 4/6 inhibitors...
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Acute Pancreatitis in a Pregnant Patient with Type IV Hyperlipoproteinemia

Lee SH, Jun JH, Doh YS, Jang JW, Kim SH, Baek IH, Jung SH

Most cases of hypertriglyceridemia (HTG)-induced gestational pancreatitis occur when a person with hyperlipidemia is overweight due to pregnancy or has secondary triggers associated with triglycerides (TGs). In Korea, 6 cases...
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Hepatic Failure Due to Hepatitis E Virus Infection in a Patient with Necrotic Hepatocellular Carcinoma

Kim JH, Doh YS, Jang JW, Kang MS, Kim NM, Kim SH, Baek IH, Jung SH

In patients with hepatocellular carcinoma (HCC) or liver cirrhosis (LC) accompanied by hepatitis E virus (HEV) infection, hepatic failure often leads to debility. Here, we report about a 63-year-old man...
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Discrepancy between the Actual Clinical Status of Patients with Hepatocellular Carcinoma and Expectations from Hepatocellular Carcinoma Surveillance: a Single-Center Study

Kim NM, Doh YS, Jang JW, Kim SH, Eun HS, Jun JH, Kim SH, Baek IH, Jung SH

BACKGROUND/AIMS: The National Liver Cancer Screening Program (NLCSP) has been implemented for the past 15 years in Korea. However, the actual clinical experience in Korea is inconsistent with the expectations...
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Meta-analysis on the Efficacy of Glutamate Receptor Antagonists for Acute Migraine Treatment

Kim S, Baek IH

BACKGROUND: Glutamate is implicated in the pathophysiology of migraine, a common neurological disorder. Therefore, glutamate receptor antagonists (GluRAs) have been suggested as a novel migraine treatment that are able to...
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Selective Biliary Cannulation for a Papilla in the 9 o'clock Position Using Pull and Rotatable Sphincterotome

Jun JH, Doh YS, Jang JW, Baek IH, Jung SH

No abstract available.
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PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD–RIG-I–NF-κB axis

Kim HK, Lee GH, Bhattarai , Junjappa R, Lee HY, Handigund , Marahatta , Bhandary B, Baek IH, Pyo JS, Kim HK, Chai OH, Kim HR, Lee YC, Chae HJ

Hyperactivation of phosphoinositol 3-kinase (PI3K) has been suggested to be a potential mechanism for endoplasmic reticulum (ER) stress-enhanced airway hyperresponsiveness, and PI3K inhibitors have been examined as asthma therapeutics. However,...
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Common Bile Duct Stone Removal with Side-viewing Duodenoscope after Forward-Viewing Endoscope-Guided Pancreatic Stent Insertion in a Patient with Periampullary Diverticulum

Jun JH, Jang JW, Kim SH, Baek IH, Jung SH

No abstract available.
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A Comparison of International Guidelines for Pediatric Asthma Pharmacotherapy

Kwon TH, Sohn K, Baek IH

OBJECTIVE: International institutes such as Global institute for Asthma(GINA), KAAACI(Republic of Korea), NHLBI(USA), BTS(UK) and JSA(Japan) have published guidelines for asthma treatment. The aim of this study was to compare...
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Comparative Study of First-in-Human Dose Estimation Approaches using Pharmacometrics

Baek IH

OBJECTIVE: First-in-human dose estimation is an essential approach for successful clinical trials for drug development. In this study, we systematically compared first-in-human dose and human pharmacokinetic parameter estimation approaches. METHODS: First-in-human...
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A Comparative Study of USA and Europe Guidelines of Rate and Rhythm Control Pharmacotherapy in Atrial Fibrillation

Jung EJ, Sohn K, Baek IH

OBJECTIVE: Atrial fibrillation (AF) guidelines have been published in the USA and Europe. Recently, the USA and Europe have updated their guidelines, respectively. These new AF guidelines help in addressing...
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A Voxel Wise Analysis of Cerebral Beta Amyloid Retention in Healthy Controls and Subjects with Amnestic Mild Cognitive Impairment and Alzheimer's Disease

Cho Y, Um YH, Kim TW, Seo HJ, Jeong JH, Hong SC, Han JH, Baek IH, Lim HK

OBJECTIVE: The purpose of the study was to compare cortical amyloid deposition using 18F-florbetaben and positron emission tomography (PET) in healthy controls and subjects with amnestic mild cognitive impairment (aMCI)...
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Cerebral venous thrombosis in a patient with Crohn's disease

Cho YH, Chae MK, Cha JM, Lee JI, Joo KR, Shin HP, Baek IH, Jeon JW, Lim JU, Hong IT, Ki HJ, Kang JB

Patients with inflammatory bowel disease (IBD) have an elevated risk of venous thromboembolism compared with the general population. The most common sites of venous thromboembolism in IBD patients are the...
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A Case of Cavernous Lymphangioma of the Small Bowel Mesentery

Hong IT, Cha JM, Lee JI, Joo KR, Baek IH, Shin HP, Jeon JW, Lim JU

Lymphangioma is a benign vascular lesion with characteristics of subepithelial tumor which can proliferate in the lymphatic system. Lymphangioma of the small-bowel mesentery is rare, having been reported in less...
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A Comparative Study the USA, Europe and Korea Guidelines of Antiplatelet Therapy for Patients with Acute Coronary Syndrome

Jung EJ, Lee CW, Baek IH

OBJECTIVE: Patients with acute coronary syndrome (ACS) are typically managed with dual antiplatelet therapy of acetylsalicylic acid (aspirin) and P2Y12 receptor inhibitor. In this study, we discussed current and previous...
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A Patient with Duodenal Mucinous Adenocarcinoma Presenting as a Laterally Spreading Tumor

Chae MJ, Baek IH, Oh YM, Lim JU, Jeon JW, Shin HP, Joo KR, Lee JI

Primary duodenal carcinoma is rare. Duodenal mucinous adenocarcinoma (DMA) is even rarer, and its associated manifestations and typical endoscopic or imaging findings are not well characterized. Herein, we report a...
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Anaphylactic Shock Caused by Ingestion of Polyethylene Glycol

Lee SH, Cha JM, Lee JI, Joo KR, Shin HP, Baek IH, Jeon JW, Lim JU, Lee JL, Lee HM, Cho YH

Colonoscopy is the current standard method for evaluation of the colon. The diagnostic accuracy and therapeutic safety of colonoscopy depend on the quality of colonic cleansing and preparation. Generally, all...
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Comparative Genotype Analysis of Hepatitis A Virus: Two One-Year Studies in South Korea in 2002 and 2011

Baek IH, Lee HW, Kim HJ, Song MO, Yoon SK, Park JH, Chung IS, Kim W

Hepatitis A virus (HAV) positive stool samples were collected from acute hepatitis A patients during the two study periods of 2002 and 2011 in Seoul, South Korea, and their genetic...
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A Case of Acute Colonic Diverticulitis as a Complication of Colonoscopy

Park DS, Park JW, Kim SY, Jang GS, Hong EY, An JS, Kim SY, Baek IH, Kim JH, Park CK

Colonoscopy is a good diagnostic tool and facilitates treatment of various colonic diseases. Nevertheless, it can induce many serious complications such as perforation and hemorrhage. Diverticulitis has also been reported...
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