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Vinpocetine inhibits the proliferation and induces apoptosis in human colon cancer cells

Kim MK, Park HJ, Kim Y, Kim YI, Bae SK, Kim HJ, Bae MK

Vinpocetine induces anti-inflammatory effects in various inflammatory diseases via the inhibition of phosphodiesterase type-1-independent nuclear factor-κB signaling pathway and the release of inflammatory cytokines. In this study, we investigated the...
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Resveratrol inhibits cell growth via targeting the Bmi-1 pathway in YD-10B human oral squamous cell carcinoma cells

Park KE, Ok CY, Jang HO, Bae MK, Bae SK

Resveratrol has been reported to exert anticancer activity via modulation of multiple pathways and genes. In this study, we examined the effect of resveratrol on YD-10B human oral squamous cell...
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Simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX, in human plasma by liquid chromatography-tandem mass spectrometry: Applications in steady-state pharmacokinetics in patients

Chae SU, Min KL, Lee CB, Huang Z, Chang MJ, Bae SK

A sensitive and simple liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous quantification of ticagrelor and its active metabolite, AR-C124910XX from 50 µL human plasma using...
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Theracurmin Ameliorates Cognitive Dysfunctions in 5XFAD Mice by Improving Synaptic Function and Mitigating Oxidative Stress

Kim J, Kim J, Huang Z, Goo N, Bae HJ, Jeong Y, Park HJ, Cai M, Cho K, Jung SY, Bae SK, Ryu JH

As the elderly population is increasing, Alzheimer's disease (AD) has become a global issue and many clinical trials have been conducted to evaluate treatments for AD. As these clinical trials...
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Porphyromonas gingivalis lipopolysaccharide stimulates vascular smooth muscle cell migration through signal transducer and activator of transcription 3-mediated matrix metalloproteinase-9 expression

Kim Y, Park JY, Park HJ, Kim MK, Kim YI, Bae SK, Kim HJ, Bae MK

Periodontal diseases have been associated with the development of cardiovascular diseases. Accumulating evidences have indicated that Porphyromonas gingivalis, a major periodontopathic pathogen, plays a critical role in the pathogenesis of...
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Evaluating the Predictive Ability of Initial Staging F-18 FDG PET/CT for the Prognosis of Non-HodgkinMalignant Lymphoma Patients Who Underwent Stem Cell Transplantation

Park YS, Lee SM, Park JS, Bae SK, Shim HK, Lee WS, Lee SM

OBJECTIVES: This study aimed to determine the value of clinical prognostic factors and semiquantitative metabolic parameters from initial staging fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) in non-Hodgkin...
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Melatonin Rescues Human Dental Pulp Cells from Premature Senescence Induced by Hâ‚‚Oâ‚‚

Park S, Bak KJ, Ok CY, Park HJ, Jang HO, Bae MK, Bae SK

Although anti-aging activities of melatonin, a hormone secreted by the pineal gland, have been reported in senescence-accelerated mouse models and several types of cells, its impact and mechanism on the...
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Correlation of Molecular Subtypes of Invasive Ductal Carcinoma of Breast with Glucose Metabolism in FDG PET/CT: Based on the Recommendations of the St. Gallen Consensus Meeting 2013

Lee SS, Bae SK, Park YS, Park JS, Kim TH, Yoon HK, Ahn HJ, Lee SM

PURPOSE: This study aimed to investigate the relationship between the SUVmax of primary breast cancer lesions and the molecular subtypes based on the recommendations of the St. Gallen consensus meeting...
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The Effect of 1-Propanol on the Rotational Mobility of n-(9-Anthroyloxy) stearic acid in Outer Monolayers of Neuronal and Model Membranes

Ahn TY, Jin SD, Yang HJ, Yoon CD, Kim MK, An TK, Bae YJ, Seo SJ, Kim GS, Bae MK, Bae SK, Jang HO

The aim of this study was to provide a basis for the molecular mechanism underlying the pharmacological action of ethanol. We studied the effects of 1-propanol on the location of...
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Effect of hypoxia on angiogenesis-related proteins in human dental pulp cells

Kim MK, Kim SJ, Kim Y, Park HJ, Jo MJ, Bae SK, Kim HJ, Bae MK

Dental pulp is a highly vascularized tissue with high regenerative potential. Revascularization of severed vasculature in the tooth is required for pulp healing during avulsed tooth treatment. In this study,...
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Clinical Usefulness of F-18 FDG PET/CT in Papillary Thyroid Cancer with Negative Radioiodine Scan and Elevated Thyroglobulin Level or Positive Anti-thyroglobulin Antibody

Choi SJ, Jung KP, Lee SS, Park YS, Lee SM, Bae SK

PURPOSE: Elevated thyroglobulin (Tg) levels, along with a negative radioiodine scan, present a clinical problem for the diagnosis of recurrence in papillary thyroid cancer (PTC) patients. The purpose of this...
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Porphyromonas gingivalis Lipopolysaccharide Regulates Migration of Vascular Smooth Muscle Cells

Kim Y, Kim SJ, Kim MK, Park HJ, Kim HJ, Bae SK, Bae MK

Porphyromonas gingivalis, a foremost periodontal pathogen, has been known to cause periodontal diseases. Epidemiologic evidences have indicated the involvement of P. gingivalis in the development of cardiovascular diseases. In this...
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2016 Revised Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Thyroid Cancer

Yi KH, Lee EK, Kang HC, Koh Y, Kim SW, Kim IJ, Na DG, Nam KH, Park SY, Park JW, Bae SK, Baek SK, Baek JH, Lee BJ, Chung KW, Jung YS, Cheon GJ, Kim WB, Chung JH, Rho YS

No abstract available.
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Involvement of Heme Oxygenase-1 in Orexin-A-induced Angiogenesis in Vascular Endothelial Cells

Kim MK, Park HJ, Kim SR, Choi YK, Bae SK, Bae MK

The cytoprotective enzyme heme oxygenase-1 (HO-1) influences endothelial cell survival, proliferation, inflammatory response, and angiogenesis in response to various angiogenic stimuli. In this study, we investigate the involvement of HO-1...
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Isolation And Development Of Quantification Method For Cyanidin-3-glucoside And Cyanidin-3-rutinoside In Mulberry Fruit By High-performance Countercurrent Chromatography And High-performance Liquid Chromatography

Choi SJ, Jeon H, Lee CU, Yoon SH, Bae SK, Chin YW, Yoon KD

Cyanidin-3-glucoside (C3G) and cyanidin-3-rutinoside (C3R) were isolated by high-performance countercurrent chromatography (HPCCC) using a two-phase solvent system composed of tert-butyl methyl ether/n-butanol/acetonitrile/water/trifluoroacetic acid (1 : 3 : 1 : 5...
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Performance Evaluation of Public Hospital Information Systems by the Information System Success Model

Cho KW, Bae SK, Ryu JH, Kim KN, An CH, Chae YM

OBJECTIVES: This study was to evaluate the performance of the newly developed information system (IS) implemented on July 1, 2014 at three public hospitals in Korea. METHODS: User satisfaction scores of...
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Characteristics of Metastatic Mediastinal Lymph Nodes of Non-Small Cell Lung Cancer on Preoperative F-18 FDG PET/CT

Lee AY, Choi SJ, Jung KP, Park JS, Lee SM, Bae SK

  • KMID: 2139216
  • Nucl Med Mol Imaging.
  • 2014 Mar;48(1):41-46.
PURPOSE: The aim of this study was to evaluate the characteristics of PETand CT features of mediastinalmetastatic lymph nodes on F-18 FDG PET/CTand to determine the diagnostic criteria in nodal...
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A Neuromedin B Receptor Blockade Inhibits the Growth of Human Oral Cancer Cells

Park HJ, Jeon JH, Kim MK, Ryu MH, Kim YD, Bae SK, Bae MK

  • KMID: 1703485
  • Int J Oral Biol.
  • 2014 Mar;39(1):1-7.
Neuromedin B (NMB) acts as a growth factor or a morphogen and plays a role in cancer progression. Indeed, the NMB receptor (NMB-R) is overexpressed in different types of tumors....
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The effect of on-line hemodiafiltration on heart rate variability in end-stage renal disease

Park KW, Bae SK, Lee B, Baek JH, Park JW, Moon SJ, Yoon SY

  • KMID: 2224307
  • Kidney Res Clin Pract.
  • 2013 Sep;32(3):127-133.
BACKGROUND: The autonomic nervous system plays a central role in the maintenance of hemodynamic stability. Cardiac autonomic dysfunction may result in serious complications, such as sudden cardiac death. Heart rate...
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Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells

Bae YH, Ryu JH, Park HJ, Kim KR, Wee HJ, Lee OH, Jang HO, Bae MK, Kim KW, Bae SK

Notch1 has been reported to be highly expressed in triple-negative and other subtypes of breast cancer. Mutant p53 (R280K) is overexpressed in MDA-MB-231 triple-negative human breast cancer cells. The present...
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