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Evaluating the recent developments in palliative chemotherapy for metastatic colorectal cancer

Baek SK, Lee KT, Bae SB, Lee SC

The incidence of colorectal cancer (CRC) has increased. CRC is the third most common cancer and the fourth most common cause of cancer-related deaths in Korea. Palliative chemotherapy can be...
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The incidence of venous thromboembolism is not lowin Korean patients with advanced pancreatic cancer

Yoon SY, Lee MY, Yoon J, Kim HJ, Kim KH, Kim SH, Lee SC, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Hong DS, Won JH

BACKGROUND: Pancreatic cancer is among the most common malignancies associated with venous thromboembolism (VTE). Asian patients are known to have a lower incidence of VTE compared to Caucasian patients. However,...
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Medical Treatment of Cancer Pain: Drug Therapy according to Guidelines Will Improve the Quality of Life of Cancer Patients

Bae SB, Lee SC

Cancer pain is the most common and troublesome symptom for cancer patients. The more the cancer patient gets to the end of the life, the worse the pain. There are...
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Association Between c-Met and Lymphangiogenic Factors in Patients With Colorectal Cancer

Kim HJ, Baek MJ, Kang DH, Lee SC, Bae SB, Lee KT, Lee N, Kim H, Jeong D, Ahn TS, Lee MS, Hong DS, Won JH

PURPOSE: Animal models show a strong relationship between lymphangiogenesis and lymph node metastasis. However, the clinical significance of lymphangiogenesis in patients with colorectal cancer (CRC) remains uncertain. This study aimed...
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CORRIGENDUM: Correction of funding statement in ACKNOWLEDGEMENTS section: Epigenetic inactivation of RUNX3 in colorectal cancer

Shin EJ, Kim HJ, Son MW, Ahn TS, Lee HY, Lim DR, Bae SB, Jeon S, Kim H, Jeong D, Lee MS, Kim DS, Noh JS, Baek MJ

Correction of funding statement in ACKNOWLEDGEMENTS section.
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Epigenetic inactivation of RUNX3 in colorectal cancer

Shin EJ, Kim HJ, Son MW, Ahn TS, Lee HY, Lim DR, Bae SB, Jeon S, Kim H, Jeong D, Lee MS, Kim DS, Noh JS, Baek MJ

PURPOSE: Emerging evidence indicates that runt-related transcription factor 3 (RUNX3) is an important tumor suppressor gene in several cancer types, including colorectal cancer (CRC). However, the clinical significance of RUNX3...
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Clinicopathologic and Prognostic Significance of Transducin-Like Enhancer of Split 1 Protein Expression in Invasive Breast Cancer

Lee JH, Bae SB, Oh MH, Cho HD, Jang SH, Hong SA, Cho J, Kim SY, Han SW, Lee JE, Kim HJ, Lee HJ

PURPOSE: Transducin-like enhancer of split 1 (TLE1) is a member of the TLE family of transcriptional co-repressors that control the transcription of a wide range of genes. We investigated the...
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Expressions and Clinical Significances of Angiopoietin-1, Angiopoietin-2, and Tie-2 Receptor in Patients With Colorectal Cancer

Hong S, Jung HI, Ahn TS, Kim HJ, Lee KT, Baek MJ, Bae SB

PURPOSE: Angiopoietin-1 (Ang-1) plays a crucial role in vascular and hematopoietic development, mainly through its cognate receptor, Tie-2. Increased levels of Ang-2 have been shown to be correlated with abnormal...
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Expression of Programmed Death Receptor Ligand 1 with High Tumor-Infiltrating Lymphocytes Is Associated with Better Prognosis in Breast Cancer

Bae SB, Cho HD, Oh MH, Lee JH, Jang SH, Hong SA, Cho J, Kim SY, Han SW, Lee JE, Kim HJ, Lee HJ

PURPOSE: The interaction of programmed death receptor 1 (PD-1) and its ligand, programmed death receptor ligand 1 (PD-L1), negatively regulates immune responses. This study aimed to clarify PD-L1 expression levels...
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Intrathecal Trastuzumab Treatment in Patients with Breast Cancer and Leptomeningeal Carcinomatosis

Park WY, Kim HJ, Kim K, Bae SB, Lee N, Lee KT, Won JH, Park HS, Lee SC

Leptomeningeal carcinomatosis is a fatal manifestation of metastatic breast cancer. Investigation of intrathecal (IT) trastuzumab for leptomeningeal carcinomatosis is currently underway; however, there has been no consensus. We report on...
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High EZH2 Protein Expression Is Associated with Poor Overall Survival in Patients with Luminal A Breast Cancer

Jang SH, Lee JE, Oh MH, Lee JH, Cho HD, Kim KJ, Kim SY, Han SW, Kim HJ, Bae SB, Lee HJ

PURPOSE: The enhancer of zeste homologue 2 (EZH2) is a catalytic subunit of the polycomb repressive complex 2, a highly conserved histone methyltransferase. EZH2 overexpression has been implicated in various...
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A Rare Case of Primary Tubular Adenocarcinoma of the Thymus, Enteric Immunophenotype: A Case Study and Review of the Literature

Jung HY, Cho H, Chung JH, Bae SB, Lee JH, Lee HJ, Jang SH, Oh MH

Thymic carcinomas are uncommon malignant tumors, and thymic adenocarcinomas are extremely rare. Here, we describe a case of primary thymic adenocarcinoma in a 59-year-old woman. Histological examination of the tumor...
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Idiopathic erythrocytosis in a patient on chronic hemodialysis

Lee DH, Min JH, Bae SB, Gil HW, Yang JO, Lee EY, Hong SY

A 78-year-old man on hemodialysis presented to our hospital with erythrocytosis. He had started hemodialysis 4 years previously, with a hemoglobin level of 9.8 g/dL, and was administered erythropoiesis stimulating...
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Second-Line Chemotherapy in Advanced Biliary Tract Cancer: A Retrospective Analysis

Kim HJ, Yun J, Kim HJ, Kim KH, Kim SH, Lee SC, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Won JH, Choi HJ, Moon JH, Hong DS

OBJECTIVE: The evidence of 2nd line chemotherapy has not been validated. We investigated the treatment outcomes of 2nd line palliative chemotherapy in patients with biliary tract cancer (BTC) and analyzed...
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Loss of Tumor Suppressor ARID1A Protein Expression Correlates with Poor Prognosis in Patients with Primary Breast Cancer

Cho HD, Lee JE, Jung HY, Oh MH, Lee JH, Jang SH, Kim KJ, Han SW, Kim SY, Kim HJ, Bae SB, Lee HJ

PURPOSE: Somatic mutations of the chromatin remodeling AT-rich interactive domain 1A (SWI-like) gene (ARID1A) have been identified in many human cancers, including breast cancer. The purpose of this study was...
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Hereditary hemorrhagic telangiectasia treated with low dose intravenous bevacizumab

Wee JW, Jeon YW, Eun JY, Kim HJ, Bae SB, Lee KT

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder that leads to mucocutaneous telangiectasias, epistaxis, and gastrointestinal bleeding. Depending on the severity and manifestation of the disease, various therapeutic modalities...
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Erratum: Comparative Analysis of Tuberculous Lymphadenitis and Kikuchi Disease of the Neck

Yoon YS, Han JK, Shin HC, Kim YT, Bae SB, Jou SS

The publisher and authors would like to draw the reader's attention to an error.
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Comparative Analysis of Tuberculous Lymphadenitis and Kikuchi Disease of the Neck

Yoon YS, Han JK, Shin HC, Kim YT, Bae SB, Jou SS

PURPOSE: To compare the clinical and CT manifestations of Kikuchi disease (KD) and tuberculous lymphadenitis (TL). MATERIALS AND METHODS: 111 patients with TL (55 men, 56 women, mean age 38.6 years,...
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Medical Findings in Korean Women with Bulimia Nervosa

Kang JK, Kim YW, Bae SB, Kim YR

  • KMID: 2343632
  • J Korean Neuropsychiatr Assoc.
  • 2013 Sep;52(5):365-371.
OBJECTIVES: Medical complications are common and often serious in patients with eating disorders, however, little is known about complications in patients with bulimia nervosa. METHODS: We conducted a retrospectively investigation of...
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Expression of Secreted Protein Acidic and Rich in Cysteine in the Stroma of a Colorectal Carcinoma is Associated With Patient Prognosis

Kim JY, Jeong D, Ahn TS, Kim HJ, Park DS, Park SY, Bae SB, Lee S, Lee SS, Lee MS, Cho HD, Baek MJ

PURPOSE: Secreted protein acidic and rich in cysteine (SPARC), also known as osteonectin or basement-membrane-40 (BM-40), is a member of a family of matricellular proteins, whose functions are to modulate...
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