- Grape seed proanthocyanidin extract ameliorates murine autoimmune arthritis through regulation of TLR4/MyD88/NF-κB signaling pathway
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Kim SH, Bang J, Son CN, Baek WK, Kim JM
- KMID: 2411590
- Korean J Intern Med.
- 2018 May;33(3):612-621.
- doi: 10.3904/kjim.2016.053
BACKGROUND/AIMS: Grape seed proanthocyanidin extract (GSPE) has been reported to have a beneficial effect on regulating inf lammation. However, the anti-inflammatory mechanism of GSPE remains unclear. The aim of this... -
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- Effects of proanthocyanidin, a crosslinking agent, on physical and biological properties of collagen hydrogel scaffold
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Choi Y, Kim HJ, Min KS
- KMID: 2356006
- Restor Dent Endod.
- 2016 Nov;41(4):296-303.
- doi: 10.5395/rde.2016.41.4.296
OBJECTIVES: The purpose of the present study was to evaluate the effects of proanthocyanidin (PAC), a crosslinking agent, on the physical properties of a collagen hydrogel and the behavior of... -
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- Anti-inflammatory effects of proanthocyanidin-rich red rice extract via suppression of MAPK, AP-1 and NF-κB pathways in Raw 264.7 macrophages
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Limtrakul , Yodkeeree , Pitchakarn P, Punfa W
- KMID: 2342126
- Nutr Res Pract.
- 2016 Jun;10(3):251-258.
- doi: 10.4162/nrp.2016.10.3.251
BACKGROUND/OBJECTIVES: Several pharmacological properties of red rice extract have been reported including anti-oxidant, anti-tumor, and reduced cancer cell invasion. This study was conducted to evaluate the anti-inflammatory effects of red... -
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- Gastroprotective Effects of Grape Seed Proanthocyanidin Extracts against Nonsteroid Anti-Inflammatory Drug-Induced Gastric Injury in Rats
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Kim TH, Jeon EJ, Cheung DY, Kim CW, Kim SS, Park SH, Han SW, Kim MJ, Lee YS, Cho ML, Chang JH, Min JK, Kim JI
- KMID: 1431340
- Gut Liver.
- 2013 May;7(3):282-289.
- doi: 10.5009/gnl.2013.7.3.282
BACKGROUND/AIMS: To investigate the gastroprotective effects of grape seed proanthocyanidin extracts (GSPEs) against nonsteroid anti-inflammatory drug (NSAID)-induced gastric mucosal injury in rats. METHODS: Sprague-Dawley rats were randomly allocated to the normal... -
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- Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis
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Woo YJ, Joo YB, Jung YO, Ju JH, Cho ML, Oh HJ, Jhun JY, Park MK, Park JS, Kang CM, Sung MS, Park SH, Kim HY, Min JK
- KMID: 1123368
- Exp Mol Med.
- 2011 Oct;43(10):561-570.
- doi: 10.3858/emm.2011.43.10.062
Osteoarthritis (OA) is an age-related joint disease that is characterized by degeneration of articular cartilage and chronic pain. Oxidative stress is considered one of the pathophysiological factors in the progression... -
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- Antioxidant activity and analysis of proanthocyanidins from pine (Pinus densiflora) needles
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Park YS, Jeon MH, Hwang HJ, Park MR, Lee SH, Kim SG, Kim M
- KMID: 2313529
- Nutr Res Pract.
- 2011 Aug;5(4):281-287.
In this study, we evaluated the antioxidant activity of pine needle extracts prepared with hot water, ethanol, hexane, hot water-hexane (HWH), and hot water-ethanol (HWE), using the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical... -
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- Comparison of methods for proanthocyanidin extraction from pine (Pinus densiflora) needles and biological activities of the extracts
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Kim NY, Jang MK, Lee DG, Yu KH, Jang H, Kim M, Kim SG, Yoo BH, Lee SH
- KMID: 2421535
- Nutr Res Pract.
- 2010 Feb;4(1):16-22.
Flavonoids are known to be effective scavengers of free radicals. In particular, proanthocyanidins are flavonoids that possess cardiovascular protection, antioxidative activities, and immunomodulatory activities. Here, we evaluated proanthocyanidin contents in... -
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