- Artificial Intelligence in Breast Cancer Diagnosis and Personalized Medicine
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Ahn JS, Shin S, Yang SA, Park EK, Kim KH, Cho SI, Ock CY, Kim S
- KMID: 2547538
- J Breast Cancer.
- 2023 Oct;26(5):405-435.
- doi: 10.4048/jbc.2023.26.e45
Breast cancer is a significant cause of cancer-related mortality in women worldwide. Early and precise diagnosis is crucial, and clinical outcomes can be markedly enhanced. The rise of artificial intelligence... -
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- Understanding of Pathomechanisms and Clinical Practice for Vitiligo
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Tanemura A
- KMID: 2546610
- Ann Dermatol.
- 2023 Oct;35(5):333-341.
- doi: 10.2021/ad.23.065
Vitiligo is a disease caused by the acquired depletion of melanocytes and/or melanocyte precursor cells in response to genetic and environmental factors, resulting in depigmentation of the entire body. It... -
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- Recent Update of Targeted Therapy in Cholangiocarcinoma
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Lee J, Kim DU
- KMID: 2544814
- Korean J Pancreas Biliary Tract.
- 2023 Jul;28(3):59-66.
- doi: 10.15279/kpba.2023.28.3.59
Cholangiocarcinoma (CCA) is one of the cancers with the worst prognosis. Its incidence and mortality have increased in recent years, but treatment options are limited. Although various clinical trials have... -
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- Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA
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Yoon JK, Ahn J, Kim S, Kim HP, Kang Jk, Bang D, Lim Y, Kim TY
- KMID: 2544184
- Cancer Res Treat.
- 2023 Jul;55(3):1048-1052.
- doi: 10.4143/crt.2022.1529
Poly(ADP-ribose) polymerase inhibitors have been shown dramatic responses in patients with BRCAness. However, clinical studies have been limited to breast cancer patients with germline mutations. Here, we describe a patient... -
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- Precision Medicine in Head and Neck Cancer
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Park Hs, Kang JH
- KMID: 2542625
- Korean J Head Neck Oncol.
- 2023 May;39(1):1-9.
- doi: 10.21593/kjhno/2023.39.1.1
Technological advancement in human genome analysis and ICT (information & communication technologies) brought ‘precision medicine’ into our clinical practice. Precision medicine is a novel medical approach that provides personalized treatments... -
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- Genetic Factors in the Screening and Imaging for Breast Cancer
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Kim J, Haffty BG
- KMID: 2541957
- Korean J Radiol.
- 2023 May;24(5):378-383.
- doi: 10.3348/kjr.2023.0012
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- Opening the Precision Diabetes Care through Digital Healthcare
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Lee J, Yu J, Yoon KH
- KMID: 2542507
- Diabetes Metab J.
- 2023 May;47(3):307-314.
- doi: 10.4093/dmj.2022.0386
The national healthcare systems of every country in the world cannot sustain the rise in healthcare expenditure caused by chronic diseases and their complications. To sustain the national healthcare system,... -
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- Eating, diet, and nutrition for the treatment of non-alcoholic fatty liver disease
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Semmler G, Datz C, Trauner M
- KMID: 2539805
- Clin Mol Hepatol.
- 2023 Feb;29(Suppl):S244-S260.
- doi: 10.3350/cmh.2022.0364
Nutrition and dietary interventions are a central component in the pathophysiology, but also a cornerstone in the management of patients with non-alcoholic fatty liver disease (NAFLD). Summarizing our rapidly advancing... -
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- Strategy of Patient-Specific Therapeutics in Cardiovascular Disease Through Single-Cell RNA Sequencing
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Jung Y, Kim J, Jang H, Kim G, Kwon YW
- KMID: 2538101
- Korean Circ J.
- 2023 Jan;53(1):1-16.
- doi: 10.4070/kcj.2022.0295
Recently, single cell RNA sequencing (scRNA-seq) technology has enabled the discovery of novel or rare subtypes of cells and their characteristics. This technique has advanced unprecedented biomedical research by enabling... -
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- Immunologic Basis of Type 2 Biologics for Severe Asthma
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Sim S, Choi Y, Park HS
- KMID: 2538487
- Immune Netw.
- 2022 Dec;22(6):e45.
- doi: 10.4110/in.2022.22.e45
Asthma is a chronic airway inflammatory disease characterized by reversible airway obstruction and airway hyperreactivity to various environmental stimuli, leading to recurrent cough, dyspnea, and wheezing episodes. Regarding inflammatory mechanisms,... -
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- Machine Learning vs. Statistical Model for Prediction Modelling: Application in Medical Imaging Research
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Ryu L, Han K
- KMID: 2536812
- J Korean Soc Radiol.
- 2022 Nov;83(6):1219-1228.
- doi: 10.3348/jksr.2022.0111
Clinical prediction models has been increasingly published in radiology research. In particular, as a radiomics research is being actively conducted, the prediction model is developed based on the traditional statistical... -
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- Update on Diagnosis and Treatment of Colorectal Cancer
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Kim CW
- KMID: 2534746
- Ewha Med J.
- 2022 Oct;45(4):e8.
- doi: 10.12771/emj.2022.e8
The rate of colorectal cancer (CRC) has altered. Early-onset CRC patients are increasing, and it is one of the main causes of cancer-related death. Based on epidemiologic change, the CRC... -
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- Clinical Implication of Molecular Tumor Board
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Lee S
- KMID: 2534386
- Korean J Med.
- 2022 Oct;97(5):319-322.
- doi: 10.3904/kjm.2022.97.5.319
Due to rapid technical advances, steeply declining sequencing costs, and the ever-increasing number of targeted therapies, it is expected that extensive tumor DNA or RNA sequencing will be applied in... -
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- Imaging Findings of 18F‑Choline and 18F‑DOPA PET/MRI in a Case of Glioblastoma Multiforme Pseudoprogression: Correlation with Clinical Outcome
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Filippi L, Spanu A, Bagni O, Schillaci O, Palumbo B
- KMID: 2534412
- Nucl Med Mol Imaging.
- 2022 Oct;56(5):245-251.
- doi: 10.1007/s13139-022-00758-2
We describe the case of 74-year-old-male, previously treated with fronto-parietal craniotomy due to primary glioblastoma multiforme (GBM), followed by concurrent radiation therapy (RT) and temozolomide (TMZ) chemotherapy. Magnetic resonance imaging... -
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- Clinical Application of Next-Generation Sequencing in Patients With Breast Cancer: Real-World Data
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Suh KJ, Kim SH, Kim YJ, Shin H, Kang E, Kim EK, Lee S, Woo JW, Na HY, Ahn S, Jang BS, Kim IA, Park SY, Kim JH
- KMID: 2534774
- J Breast Cancer.
- 2022 Oct;25(5):366-378.
- doi: 10.4048/jbc.2022.25.e30
Purpose: Next-generation sequencing (NGS)-based tumor panel testing has been reimbursed by the Korean government since 2017. We evaluated the use of NGS-based tumor panel testing in real-world clinical practice, focusing... -
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- Deep learning-based prediction of molecular cancer biomarkers from tissue slides: A new tool for precision oncology
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Lee SH, Jang HJ
- KMID: 2534341
- Clin Mol Hepatol.
- 2022 Oct;28(4):754-772.
- doi: 10.3350/cmh.2021.0394
Molecular tests are necessary to stratify cancer patients for targeted therapy. However, high cost and technical barriers limit the application of these tests, hindering optimal treatment. Recently, deep learning (DL)... -
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- Maturity-Onset Diabetes of the Young (MODY)
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Park SS, Kwak SH
- KMID: 2534301
- J Korean Diabetes.
- 2022 Sep;23(3):157-164.
- doi: 10.4093/jkd.2022.23.3.157
Precision medicine, which optimizes diagnosis and treatment of diseases according to individualized characteristics, is becoming a reality in the field of diabetes, especially for monogenic diabetes. Maturityonset diabetes of the... -
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- Establishment of Patient-Derived Gastric Cancer Organoid Model From Tissue Obtained by Endoscopic Biopsies
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Song H, Park JY, Kim JH, Shin TS, Hong SA, Huda MN, Kim BJ, Kim JG
- KMID: 2531802
- J Korean Med Sci.
- 2022 Jul;37(28):e220.
- doi: 10.3346/jkms.2022.37.e220
Cancer organoids are three-dimensional mini-organ analogues derived from cancer tissues and have been proposed as models capable of simulating the structure and function of human organs and tissues in vitro.... -
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- Precision Medicine in Type 2 Diabetes
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Jeon E
- KMID: 2531490
- J Korean Diabetes.
- 2022 Jun;23(2):77-82.
- doi: 10.4093/jkd.2022.23.2.77
Precision medicine is an innovative approach to tailoring disease prevention and treatment that takes into account differences in people’s genes, environments, and lifestyle patterns. The aim of such an approach... -
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- Concept and Proof of the Lifelog Bigdata Platform for Digital Healthcare and Precision Medicine on the Cloud
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Lee KH, Urtnasan E, Hwang S, Lee HY, Lee JH, Koh SB, Youk H
- KMID: 2524807
- Yonsei Med J.
- 2022 Jan;63(S1):84-92.
- doi: 10.3349/ymj.2022.63.S84
Purpose: We propose the Lifelog Bigdata Platform as a sustainable digital healthcare system based on individual-centric lifelog datasets and describe the standardization of lifelog and clinical data in its full-cycle... -
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