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Diffuse Cerebellar Dysfunction as a Permanent Neurological Sequela of Organophosphate Poisoning: A Case Report

Kim HA, Lee H

The diffuse cerebellar dysfunction as a permanent neurological sequela of organophosphate poisoning has not yet been reported in the published literature. We report a diffuse cerebellar dysfunction as a permanent...
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Assessment and Methods of Nutritional Support during Atropinization in Organophosphate and Carbamate Poisoning Cases

Park Ju, Min Yg, Choi S, Ko Dw, Park EJ

Purpose: Atropine is an antidote used to relieve muscarinic symptoms in patients with organophosphate and carbamate poisoning. Nutritional support via the enteral nutrition (EN) route might be associated with improved...
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Study of ethion and lipopolysaccharide interaction on lung in a mouse model

Verma G, Sethi RS

Ethion is an organophosphate used commonly in India despite being banned in many other countries. The present study was designed to study the interaction of ethion and lipopolysaccharide (LPS) together...
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Acetylcholinesterase activity in the brain of wild birds in Korea—2014 to 2016

Bang JH, Ku HO, Kang HG, Kim H, Kim S, Park SW, Kim YS, Jang I, Bae YC, Woo GH, Yi H

Acetylcholinesterase (AChE) activity level can be used as a diagnostic marker for anticholinesterase pesticide poisoning. In this study, we aimed to establish a baseline level of normal brain AChE activity...
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Relative Risk and Clinical Severity Assessment in Patients with Non-Oral Route Organophosphate Poisoning Compared with Oral Route Poisoning

Jung WJ, Yu MH, Lee Y, Kim H, Cha YS, Park KH

PURPOSE: Organophosphates, commonly used in agricultural pesticides, pose high risks and incidences of poisoning. In the present study, we investigated the relative risk and clinical severity, including laboratory results, of...
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Sudden death caused by trichlorfon poisoning in Korean native cattle

Kim JH, Lee K, Jung JY, Yi H, Sohn JH, So B, Choi EJ

Two 12-month-old cattle with anthelmintics containing trichlorfon the day before death presented to the Animal and Plant Quarantine Agency for diagnosis. In necropsy, they revealed enlargement of the spleens, redness...
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A Case of a Child with Seizure caused by Organophosphate Poisoning

Jang JH, Lee Y, Lee JH, Oh JH, Kim JH, Yoo IH

Seizure is a temporary symptom or sign which is caused by an abnormal electrical stimulation of brain. Depending on whether a seizure has preceding factors or not, it can be...
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Different Clinical Courses for Poisoning with WHO Hazard Class Ia Organophosphates EPN, Phosphamidon, and Terbufos in Humans

Mun JG, Moon JM, Lee MJ, Chun BJ

PURPOSE: Extremely hazardous pesticides are classified as World Health Organization (WHO) hazard class Ia. However, data describing the clinical course of WHO class Ia OP (organophosphate) poisonings in humans are...
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Intermediate syndrome after dermal exposure to organophosphate insecticide

Lee SB, Ryu SH, Park DY, Park JH, Kim JY

Intermediate syndrome (IMS) typically occurs at 24–96 hours following organophosphate (OP) poisoning, after an acute cholinergic crisis, but before OP-induced delayed polyneuropathy. It is characterized by proximal muscle weakness and...
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Methidathion Poisoning

Kim KH, Kim SH, Her C

Although methidathion is an organophosphate insecticide, it is different from the other organophosphates in terms of toxicity. Because of its relatively high fat solubility, the apparent volume of methidathion distribution...
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Implementing Best Practice in Critically Ill Organophosphate Poisoned Patient Through Simulation-Based Learning Program

Lee JH, Chung SP, Chung HS

PURPOSE: Despite the clinical and socio-economic impact of acute poisoned patients, many of the treatments are not standardized in Korea. Moreover, no formal training that is specifically focused on clinical...
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Hypoalbuminemia as a Predictor of 30-day Mortality in Patients with Acute Organophosphate Insecticide Poisoning

Kim SY, Lee RK, Kim TH, Kim DH, Kim T, Lee SH, Jeong JH, Lee SB, Kang C

PURPOSE: The association of hypoalbuminemia with 30-day in-hospital mortality in patients with organophosphate insecticide poisoning (OPI) was studied. METHODS: This retrospective cohort study was conducted between January 2006 and November 2013...
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Acute Kidney Injury after Intravenous Injection of an Organophosphate Compound

Lee JY, Sung WY, Lee IY, Seo SW, Lee WS

Poisoning may result from self-injection. Previous reports have described acute cholinergic crisis, intermediate syndrome, and delayed toxicity resulting from parenteral organophosphate administration. These complications have been managed with antidotal and...
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Blood Lipid Profile as a Prognostic Factor in Patients with Organophosphate Poisoning

Han DG, Kim DH, Park YJ

PURPOSE: The purpose of this study is to compare clinical outcomes with blood lipids level and lipid solubility of organophosphate-poisoned patients. METHODS: Data from 88 patients who visited the emergency room...
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Study on Current Changes of Atropine Regimen in Organophosphate Pesticides Poisoning

Kim MS, Jin SC, Kim SJ, Choi WI

Appropriate early atropinization is important for the recovery and prognosis of the organophosphate pesticides poisoning patient. However, recommended guidelines of atropine regimen in the treatment of organophosphate pesticides poisoning is...
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Evaluation of Cardiac Function by Transthoracic Echocardiography in Patients with Myocardial Injury Secondary to Organophosphate Poisoning

Lee Y, Kim OH, Kim HI, Cha KC, Kim H, Lee KH, Hwang SO, Cha YS

  • KMID: 2133230
  • J Korean Soc Clin Toxicol.
  • 2015 Dec;13(2):62-70.
PURPOSE: Cardiac complications may occur in cases of organophosphate (OP) poisoning. However, a few studies regarding patterns of cardiac toxicity as determined by transthoracic echocardiography (TTE) after exposure to OP...
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Initial Blood Glucose Can Predict the Outcome of OP Poisoning

Lee SD, Moon JM, Chun BJ

  • KMID: 2133229
  • J Korean Soc Clin Toxicol.
  • 2015 Dec;13(2):55-61.
PURPOSE: Many studies have examined the mechanisms of impaired glucose homeostasis after organophosphate (OP) exposure, however no study has evaluated the clinical utility of blood glucose measurements in patients with...
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Effect of Alcohol on Death Rate in Organophosphate Poisoned Patients

Min YH, Park SM, Lee KJ, Oh YT, Ahn HC, Sohn YD, Ahn JY, Lee YH, Ha SO, Kim YJ

  • KMID: 1846319
  • J Korean Soc Clin Toxicol.
  • 2015 Jun;13(1):19-24.
PURPOSE: Many patients who are acutely poisoned with organophosphorus pesticides have co-ingested alcohol. The purpose of this study was to identify the factors that influence mortality in organophosphate intoxication and...
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Left Facial Swelling Caused by Organophosphate (Dichlorvos) Poisoning: A Case Report and Review of the Literature

Park DH

  • KMID: 2333843
  • J Korean Soc Emerg Med.
  • 2014 Jun;25(3):318-322.
In organophosphate intoxication, the neurotransmitter acetylcholine accumulates in synapses, causing excessive stimulation of nicotinic and muscarinic receptors, producing various signs and symptoms. Organophosphates are highly toxic compounds that are readily...
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Trends of Lipase and General Features in Organophosphates Induced Acute Pancreatitis

Cho NH, Kim H, Jung WJ, Kim YW, Kim TH, Kim OH, Cha KC, Lee KH, Hwang SO, Cha YS

  • KMID: 2333837
  • J Korean Soc Emerg Med.
  • 2014 Jun;25(3):277-283.
PURPOSE: There have been few case reports and studies on acute pancreatitis associated with organophosphate (OP) poisoning. We investigated prevalence, general characteristics, trends of lipase levels, and findings of computed...
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