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Characterization of Plasmodium berghei Homologues of T-cell Immunomodulatory Protein as a New Potential Candidate for Protecting against Experimental Cerebral Malaria

Cui A, Li Y, Zhou X, Wang L, Luo E

The pathogenesis of cerebral malaria is biologically complex and involves multi-factorial mechanisms such as microvascular congestion, immunopathology by the pro-inflammatory cytokine and endothelial dysfunction. Recent data have suggested that a...
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Age-Related CD4+CD25+Foxp3+ Regulatory T-Cell Responses During Plasmodium berghei ANKA Infection in Mice Susceptible or Resistant to Cerebral Malaria

Shan Y, Liu J, Pan YY, Jiang YJ, Shang H, Cao YM

Different functions have been attributed to CD4+CD25+Foxp3+ regulatory T-cells (Tregs) during malaria infection. Herein, we describe the disparity in Treg response and pro- and anti-inflammatory cytokines during infection with Plasmodium...
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Multiple Cerebral Infarcts Following Acute Plasmodium vivax Infection

Jang YK, Minn YK, Cho SJ, Kwon KH

  • KMID: 2288700
  • Korean J Stroke.
  • 2012 Dec;14(3):149-151.
Cerebral malaria is a severe neurological complication of Plasmodium falciparum infection. Cerebral malaria can lead to cerebral infarction by several mechanisms including systemic inflammatory response. The systemic inflammatory response is...
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A Case of Plasmodium Vivax Malaria with Cerebral Complications

Kwon SH, Goong HJ, Lee EJ, Jeon MH, Kim TH, Park SA, Choo EJ

  • KMID: 2264259
  • Korean J Med.
  • 2012 Mar;82(3):382-385.
A 51-year-old man diagnosed with Plasmodium vivax malaria was transferred to our clinic with newly developed drowsy mentality and myoclonus after the initiation of hydroxychloroquine therapy. Following therapy to treat...
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Possible Role of Heme Oxygenase-1 and Prostaglandins in the Pathogenesis of Cerebral Malaria: Heme Oxygenase-1 Induction by Prostaglandin D2 and Metabolite by a Human Astrocyte Cell Line

Kuesap J, Na-Bangchang K

Astrocytes are the most abundant cells in the central nervous system that play roles in maintaining the blood-brain-barrier and in neural injury, including cerebral malaria, a severe complication of Plasmodium...
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A Case of Plasmodium vivax Malaria with Cerebral Complicatio

Kim M, Kim G, Kang Y, Kim NH, Jeon JH, Park WB, Kim HB, Kim NJ, Park SW, Hong YH, Oh MD

Plasmodium vivax malaria is an endemic disease in Korea, which rarely causes severe complications including those occurring in the cerebrum. There are limited numbers of complicated cases that have been...
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A Case of Vivax Malaria with Seizure and Shock

Yoon SG, Kim MH, Jung ES, Han KH, Kwak YG, Cho CR, Um TH, Kim ES

  • KMID: 1528889
  • Infect Chemother.
  • 2007 Aug;39(4):226-229.
Vivax malaria reemerged in the Republic of Korea in 1993. Vivax malaria is generally a benign disease with few severe complications. Even in the worldwide literature, there is only a...
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Two Cases of Cerebral Malaria Treated with Therapeutic Erythrocytapheresie

Song JW, Kim CK, Lee WH, Lim HS, Kim HO, Kim JM

  • KMID: 2039273
  • Korean J Blood Transfus.
  • 2003 Dec;14(2):234-239.
Cerebral malalria is a life-threatening complication of Plasmodium falciparum infection. RBC exchange transfusion (RCE) can reduce the burden of parasitemia in this situation. We have experienced two cases of cerebral...
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Cerebral Malaria Associated with Retinal Hemorrhage on Macular Area

Oh J, Kim HS, Huh K

  • KMID: 2337131
  • J Korean Ophthalmol Soc.
  • 2003 Nov;44(11):2699-2704.
PURPOSE: Cerebral malaria is caused by Plasmodium falciparum. The reports about cerebral malaria are very rare because Korea is not endemic area of P. falciparum. Additionally, macular hemorrhage and decreased...
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Genetic factors associated with development of cerebral malaria and fibrotic schistosomiasis

Hirayama K

Collaborative studies have identified some genetic factors contributing to the development of severe forms of malaria and schistosomiasis. In Thailand, the TNF-alpha 5'-flanking region shows biallelic polymorphic sites at nucleotides...
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A Case of Cerebral Malaria Associated with Renal Failure due to Plasmodium falciparum

Kang MS, Choi JW, Nahm CH, Pai SH

  • KMID: 2225961
  • Korean J Clin Pathol.
  • 2000 Oct;20(5):459-462.
In recent years, the incidence of imported cases infested with Plasmodium falciparum has been increasing in Korea due to marked increase in travel to malarious area without adequate prophylaxis. Cerebral...
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A mixed cerebral infection of vivax and falciparum malaria

Kim JM, Yoo TH, Park CJ, Chi HS

  • KMID: 2225944
  • Korean J Clin Pathol.
  • 2000 Jun;20(3):263-267.
Mixed falciparum-vivax infection accounts for 5% of all malaria cases seen in endemic region. However, a larger proportion of mixed malaria cases develop cerebral complication. We report one case of...
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