Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

103 results
Display

Glial Cell Line-derived Neurotrophic Factor-overexpressing Human Neural Stem/Progenitor Cells Enhance Therapeutic Efficiency in Rat with Traumatic Spinal Cord Injury

Hwang K, Jung K, Kim IS, Kim M, Han J, Lim J, Shin JE, Jang JH, Park KI

Spinal cord injury (SCI) causes axonal damage and demyelination, neural cell death, and comprehensive tissue loss, resulting in devastating neurological dysfunction. Neural stem/progenitor cell (NSPCs) transplantation provides therapeutic benefits for...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Preemptive application of QX-314 attenuates trigeminal neuropathic mechanical allodynia in rats

Yoon JH, Son JY, Kim MJ, Kang SH, Ju JS, Bae YC, Ahn DK

The aim of the present study was to examine the effects of preemptive analgesia on the development of trigeminal neuropathic pain. For this purpose, mechanical allodynia was evaluated in male...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Cold Allodynia after C2 Root Resection in Sprague-Dawley Rats

Chung D, Cho DC, Park SH, Kim KT, Sung JK, Jeon Y

OBJECTIVE: The purpose of this study was to evaluate pain-related behaviors after bilateral C2 root resection and change in pain patterns in the suboccipital region in rats. METHODS: Male Sprague-Dawley rats...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model

Fujita M, Fukuda T, Sato Y, Takasusuki T, Tanaka M

BACKGROUND: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Intravenous Administration of Substance P Attenuates Mechanical Allodynia Following Nerve Injury by Regulating Neuropathic Pain-Related Factors

Chung E, Yoon TG, Kim S, Kang M, Kim HJ, Son Y

This study aimed to investigate the analgesic effect of substance P (SP) in an animal model of neuropathic pain. An experimental model of neuropathic pain, the chronic constriction injury (CCI)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The efficacy of combination treatment of gabapentin and electro-acupuncture on paclitaxel-induced neuropathic pain

Kim MJ, Lee JH, Jang JU, Quan FS, Kim SK, Kim W

Paclitaxel, a chemotherapeutic drug, induces severe peripheral neuropathy. Gabapentin (GBT) is a first line agent used to treat neuropathic pain, and its effect is mediated by spinal noradrenergic and muscarinic...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Participation of central GABAA receptors in the trigeminal processing of mechanical allodynia in rats

Kim MJ, Park YH, Yang KY, Ju JS, Bae YC, Han SK, Ahn DK

Here we investigated the central processing mechanisms of mechanical allodynia and found a direct excitatory link with low-threshold input to nociceptive neurons. Experiments were performed on male Sprague-Dawley rats weighing...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Involvement of spinal muscarinic and serotonergic receptors in the anti-allodynic effect of electroacupuncture in rats with oxaliplatin-induced neuropathic pain

Lee JH, Go D, Kim W, Lee G, Bae H, Quan FS, Kim SK

This study was performed to investigate whether the spinal cholinergic and serotonergic analgesic systems mediate the relieving effect of electroacupuncture (EA) on oxaliplatin-induced neuropathic cold allodynia in rats. The cold...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Synergistic Effect of Intrathecally Administered Dexmedetomidine and Ketorolac on Mechanical Allodynia in Rats with Spinal Nerve Ligation

Cheong YK, Kim YD, Lee JH, Ham HD, Choi SW, Park SJ

OBJECTIVES: This research was carried out to identify the synergistic effect of dexmedetomidine and ketorolac on neuropathic pain alleviation. METHODS: The anti-allodynic effect of intrathecal dexmedetomidine and ketorolac was investigated in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The effect of intrathecal baclofen single injection on neuropathic pain

Lee CA, Kim HS, Kim HY, Lee GG

BACKGROUND: Baclofen is a gamma-aminobutyric acid B-receptor agonist, which is usually used for patients with spasticity or patients with nerve injury inducing both spasticity and neuropathic pain. Both oral administration...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Reduction in mechanical allodynia in complex regional pain syndrome patients with ultrasound-guided pulsed radiofrequency treatment of the superficial peroneal nerve

Chae WS, Kim SH, Cho SH, Lee JH, Lee MS

The superficial peroneal nerve is vulnerable to damage from ankle sprain injuries and fractures as well as surgery to this region. And it is also one of the most commonly...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Differential Role of Central GABA Receptors in Nociception of Orofacial Area in Rats

Lee AR, Lim NH, Kim HJ, Kim MJ, Ju JS, Park MK, Lee MK, Yang KY, Ahn DK

The present study investigated the role of central GABA(A) and GABA(B) receptors in orofacial pain in rats. Experiments were conducted on Sprague-Dawley rats weighing between 230 and 280 g. Intracisternal...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Mechanical Antiallodynic Effect of Intrathecal Nefopam in a Rat Neuropathic Pain Model

Kim KH, Byeon GJ, Kim HY, Baek SH, Shin SW, Koo ST

Nefopam has a pharmacologic profile distinct from that of opioids or other anti-inflammatory drugs. Several recent studies demonstrate that nefopam has a mechanism of action similar to those of anti-depressants...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Olanzapine Attenuates Mechanical Allodynia in a Rat Model of Partial Sciatic Nerve Ligation

Fukuda T, Yamashita , Hisano S, Tanaka M

BACKGROUND: Neuropathic pain is a global clinical problem; nevertheless, nerve injury treatment methods remain limited. Olanzapine has antinociceptive and anti-nueropathic properties; however, its preventive effects have not been assessed in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Attenuation of Pain Behavior and Serum COX-2 Concentration by Curcumin in a Rat Model of Neuropathic Pain

Moini Zanjani T, Ameli H, Labibi F, Sedaghat K, Sabetkasaei M

BACKGROUND: Neuropathic pain is generally defined as a chronic pain state resulting from peripheral and/or central nerve injury. There is a lack of effective treatment for neuropathic pain, which may...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Antiallodynic effects of intrathecal tianeptine in a neuropathic pain rat

Lin H, Lee HG, Yoon MH

  • KMID: 1797467
  • Anesth Pain Med.
  • 2014 Apr;9(2):93-97.
BACKGROUND: Tianeptine is an antidepressant drug which is used for treating depression. Interestingly, the tianeptine has shown antinociceptive effects within a variety of nociceptions. The aim of this study is...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of Nefopam on Streptozotocin-Induced Diabetic Neuropathic Pain in Rats

Nam JS, Cheong YS, Karm MH, Ahn HS, Sim JH, Kim JS, Choi SS, Leem JG

BACKGROUND: Nefopam is a centrally acting non-opioid analgesic agent. Its analgesic properties may be related to the inhibitions of monoamine reuptake and the N-methyl-D-aspartate (NMDA) receptor. The antinociceptive effect of...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of Ethyl Pyruvate on Paclitaxel-Induced Neuropathic Pain in Rats

Choi SS, Koh WU, Nam JS, Shin JW, Leem JG, Suh JH

BACKGROUND: Although paclitaxel is a widely used chemotherapeutic agent for the treatment of solid cancers, side effects such as neuropathic pain lead to poor compliance and discontinuation of the therapy....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Anti-Allodynic Effects of Levodopa in Neuropathic Rats

Park HJ, Joo HS, Kim YH, Kwon OK, Lee J, Kim ES, Moon DE

PURPOSE: Levodopa is the most effective anti-Parkinsonian agent. It has also been known to exhibit analgesic properties in laboratory and clinical settings. However, studies evaluating its effects on neuropathic pain...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Intrathecal Gabapentin Increases Interleukin-10 Expression and Inhibits Pro-Inflammatory Cytokine in a Rat Model of Neuropathic Pain

Lee BS, Jun IG, Kim SH, Park JY

We examined the possible anti-inflammatory mechanisms of gabapentin in the attenuation of neuropathic pain and the interaction between the anti-allodynic effects of gabapentin and interleukin-10 (IL-10) expression in a rat...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr