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Dual cortical tunneling method for endoscopic forehead lift

Kim M, Lee N, Tark W, Lee WJ, Roh TS, Baek W

Background Endoscopic forehead lift with cortical tunneling is an effective option for rejuvenation of the upper third of the face. Although it has been considered safe and reliable, with relatively...
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Comprehensive investigations of key mitochondrial metabolic changes in senescent human fibroblasts

Ghneim HK, Alfhili MA, Alharbi SO, Alhusayni SM, Abudawood M, Aljaser FS, Al-Sheikh YA

There is a paucity of detailed data related to the effect of senescence on the mitochondrial antioxidant capacity and redox state of senescent human cells. Activities of TCA cycle enzymes, respiratory...
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What Is Normal for an Aging Heart?: A Prospective CMR Cohort Study

Kersten J, Hackenbroch C, Bouly M, Tyl B, Bernhardt P

BACKGROUND: This study aims to investigate normal changes throughout aging of the heart in cardiac magnetic resonance (CMR) imaging in healthy volunteers. While type 2 diabetes mellitus is a frequent...
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The Role of Mitochondrial Dynamic Dysfunction in Age-Associated Type 2 Diabetes

Vezza T, Díaz-Pozo P, Canet F, de Marañón AM, Abad-Jiménez Z, García-Gargallo C, Roldan I, Solá E, Bañuls C, López-Domènech S, Rocha M, Víctor VM

Mitochondrial dynamics, such as fusion and fission, play a critical role in maintaining cellular metabolic homeostasis. The molecular mechanisms underlying these processes include fusion proteins (Mitofusin 1 [MFN1], Mitofusin 2...
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Impact of Aging on Urinary Natriuretic Peptides in Nocturia and Nocturnal Polyuria

Khosla L, Boroda JU, Salama J, Rahman SN, Gordon DJ, Moy MW, Akivis Y, Akivis A, Lazar JM, Weiss JP, Birder LA

Purpose: The pathophysiology of nocturia and nocturnal polyuria (NP), conditions that become more prevalent with aging, may in part be explained by changes in hormones involved in water homeostasis. The...
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Aging-Associated Changes in Oxidative Stress Negatively Impacts the Urinary Bladder Urothelium

de Rijk MM, Wolf-Johnston A, Kullmann AF, Taiclet S, Kanai AJ, Shiva S, Birder LA

Purpose: Lower urinary tract symptoms are known to significantly increase with age, negatively impacting quality of life and self-reliance. The urothelium fulfills crucial tasks, serving as a barrier protecting the...
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Antimicrobial peptide nisin induces spherical distribution of macropinocytosis-like cytokeratin 5 and cytokeratin 17 following immediate derangement of the cell membrane

Kitagawa N

The anti-aging effects of Lactococcus lactis are extensively investigated. Nisin is an antimicrobial peptide produced by L. lactis subsp. lactis. We previously reported that 24-hour nisin treatment disturbs the intermediate...
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Successful Aging Transition and Its Impact on Self-Rated Health and Life Satisfaction: Findings from the Korean Longitudinal Study of Aging (2006-2018)

Seo YB, Yang YJ

Background: The concept of successful aging (SA) is becoming more emphasized. Since this status can change over time, it is necessary to evaluate the pattern of change and its effect...
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Factors Influencing Hearing Aid Satisfaction in South Korea

Kim GY, Cho YS, Byun HM, Seol HY, Lim J, Park JG, Moon IJ

Purpose: The purpose of this study is three-fold: 1) to evaluate factors influencing hearing aid (HA) satisfaction; 2) to provide a profile of HA satisfaction in daily life; and 3)...
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Fear of Falling and Environmental Factors: A Scoping Review

Rico CLV, Curcio CL

Fear of falling is a geriatric condition that must be understood from both a clinical perspective and from the environment in which older adults live. This review aimed to describe...
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Association between Muscle Strength and Anemia in the Rural Middle Age and Older Adults

Park DY, K im Y

Purpose: This study aimed to investigate the association between relative muscle strength and serum hemoglobin levels. Methods: In this study, 3,234 adults living in rural areas were surveyed from 2007 to...
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Importance of Sclerostin as Bone-Muscle Mediator Crosstalk

Aryana IGPS, Rini SS, Soejono CH

Loss of bone and muscle mass is a frequent aging condition and has become a growing public health problem. The term “osteosarcopenia” denotes close links between bone and muscle. Mechanical...
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Morus Nigra Extract Attenuates Cognition Impairment and GABAergic Interneuron Degeneration in Aged Rat Brain

Lee JH, Kim Y, Song MK, Kim YJ

Purpose: Aging process comes with cognitive impairment due to decreased neuronal cell number, activity, and neuronal circuit. Alteration of inhibitory neurons contributes to cognitive impairment in normal aging and is...
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A Study on the Relationship between Facial Skin Youthfulness and Lifestyle in Korean Women over 50 Years Old

Kim SM, Lee YY, Hwang CL, Shin JM, Kwon IS, Park SH, Jung KE, Kim CD, Seo YJ, Hong D, Lee Y

  • KMID: 2530076
  • Korean J Dermatol.
  • 2022 May;60(4):201-208.
Background: Skin aging can be divided into intrinsic and extrinsic processes, and occur due to several factors. Although the interest in skin youthfulness is increasing globally, research on facial skin...
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An Enlarged Perivascular Space: Clinical Relevance and the Role of Imaging in Aging and Neurologic Disorders

Yim Y, Moon WJ

The perivascular space (PVS) of the brain, also known as Virchow-Robin space, consists of cerebrospinal fluid and connective tissues bordered by astrocyte endfeet. The PVS, in a word, is the...
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Brain Iron Imaging in Aging and Cognitive Disorders: MRI Approaches

Jang J, Kang J, Nam Y

Iron has a vital role in the human body, including the central nervous system. Increased deposition of iron in the brain has been reported in aging and important neurodegenerative diseases....
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NAD + and Vascular Dysfunction: From Mechanisms to Therapeutic Opportunities

Abdellatif M, Bugger H, Kroemer G, Sedej S

Nicotinamide adenine dinucleotide (NAD + ) is an essential and pleiotropic coenzyme involved not only in cellular energy metabolism, but also in cell signaling, epigenetic regulation, and post-translational protein modifications....
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Thyroid Function across the Lifespan: Do Age-Related Changes Matter?

Walsh JP

Circulating concentrations of thyrotropin (TSH) and thyroxine (T4) are tightly regulated. Each individual has setpoints for TSH and free T4 which are genetically determined, and subject to environmental and epigenetic...
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Quality of life changes in elderly patients after gastrectomy: perspective of an aged Asian society in the 2010s

Jung JH, Lee SS, Chung HY

Purpose: The study aimed to investigate how elderly gastric cancer patients do postoperatively in terms of quality of life (QoL) compared to younger patients. We also investigated how the QoL...
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Prevalence and Clinical Features of Sagging Eye Syndrome in Korean Patients

Park BC, Kim DH

Purpose: To retrospectively analyze the relative frequency and describe the clinical features of sagging eye syndrome in Korean patients from a single center. Methods: We retrospectively analyzed the medical records of...
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