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Belt & road organ donation capacity improvement cooperation training project (BROAOD)

Balleste C, Manyalich M, Kondi E, Zhao H, Pu M, Zhao J, Zhao Y, Wu Y

Background: China shows a continuous improvement in the practice of organ donation (OD) and transplantation (OT); reaching 4.16 pmp in 2019. China Organ Transplantation Development Foundation (COTDF) in cooperation with...
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Proteomic Analysis on Exosomes Derived from Patients’ Sera Infected with Echinococcus granulosus

Wang W, Zhou X, Cui F, Shi C, Wang Y, Men Y, Zhao W, Zhao J

Cystic echinococcosis (CE), a zoonotic disease caused by Echinococcus granulosus at the larval stage, predominantly develops in the liver and lungs of intermediate hosts and eventually results in organ malfunction...
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MondoA Is Required for Normal Myogenesis and Regulation of the Skeletal Muscle Glycogen Content in Mice

Ran H, Lu Y, Zhang Q, Hu Q, Zhao J, Wang K, Tong X, Su Q

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Irregular Bone Defect Repair Using Tissue-Engineered Periosteum in a Rabbit Model

Zhao L, Zhao J, Yu JJ, Zhang C

BACKGROUND: In previous studies, we succeeded in repairing a long bone defect with tissue-engineered periosteum (TEP), fabricated by incorporating rabbit mesenchymal stem cells with small intestinal submucosa. In this study,...
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Whole Exome Sequencing in the Male Breast Cancer with Prolactinoma: A Case Report and Literature Review

Hao S, Huang M, Tian W, Chen Y, Zhao J, Luo D

Male breast cancer (MBC) is rare and accounts for approximately 1% of all breast cancer cases worldwide. Previous studies have suggested that several factors significantly increase the risk of MBC....
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Gastric Cancer Stem Cells: Mechanisms and Therapeutic Approaches

Fu Y, Du P, Zhao J, Hu C, Qin Y, Huang G

Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. GC stem-like cells (GCSCs), with unlimited self-renewal, differentiation, and tumor-regenerating capacities, contribute significantly to the refractory features of...
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Effects of Envy on Depression: The Mediating Roles of Psychological Resilience and Social Support

Xiang Y, Dong X, Zhao J

Objective Envy, as a stable personality trait, can affect individuals’ mental health. Specifically, previous studies have found that envy can lead to depression; however, the mechanism by which envy affects...
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Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway

Song X, Nie L, Long J, Zhao J, Liu X, Wang L, Liu D, Wang S, Liu S, Yang J

Hypothyroidism alone can lead to myocardial fibrosis and result in heart failure, but traditional hormone replacement therapy does not improve the fibrotic situation. Hydrogen sulfide (H 2 S), a new...
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Comparison of accuracy between digital and conventional implant impressions: two and three dimensional evaluations

Bi C, Wang X, Tian F, Qu Z, Zhao J

PURPOSE. The present study compared the accuracy between digital and conventional implant impressions. MATERIALS AND METHODS. The experimental models were divided into six groups depending on the implant location and...
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The Therapeutic Effects of Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells on Scleroderma

Yu Y, Shen L, Xie X, Zhao J, Jiang M

BACKGROUND: Scleroderma is a multisystem disease in which tissue fibrosis is caused by inflammation and vascular damage. The mortality of scleroderma has remained high due to a lack of effective...
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Analysis of Circulating Tumor DNA to Predict Neoadjuvant Therapy Effectiveness and Breast Cancer Recurrence

Hao S, Tian W, Zhao J, Chen Y, Zhang X, Gao B, He Y, Luo D

Purpose: Real-time detection and intervention can be used as potential measures to markedly decrease breast cancer mortality. Assessment of circulating tumor DNA (ctDNA) may offer great benefits for the management...
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Prevalence of Cystic Echinococcosis in Slaughtered Sheep as an Indicator to Assess Control Progress in Emin County, Xinjiang, China

Yang S, Wu W, Tian T, Zhao J, Chen K, Wang Q, Feng Z

Hydatid disease imposing serious threat on human health and great loss in livenotstock pastoralism remains a major public health problem in western China. To assess and monitor the effect of...
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Therapeutic responses to chemotherapy or immunotherapy by molecular subtype in bladder cancer patients: A meta-analysis and systematic review

Wang S, Yuan X, Shen Z, Zhao J, Zheng B, Zhang J, Ge C

To systematically evaluate the differences in therapeutic response to chemotherapy or immunotherapy between different molecular subtypes of bladder cancer (BC). A comprehensive literature search was performed up to December 2021....
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MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata

Qi Ss, Miao Y, Sheng Yy, Hu Rm, Zhao J, Yang Qp

Background: We found microRNA (miR)-1246 to be significantly differentially expressed between severe active alopecia areata (AA) patients and healthy individuals. Objective: To explore the role and mechanism of miR-1246 in severe...
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Chronological changes in epidemiologic features of patients with gallstones over the last 20 years in a single large-volume Korean center

Zhao J, Kim H, Han Y, Choi YJ, Byun Y, Kwon W, Jang JY

PURPOSE: South Korea has a high prevalence of gallstones, the type of which could be influenced by changes in diet and socioeconomic status. Here we aimed to investigate the epidemiological...
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Distribution of pathological types and epidemiological characteristics based on kidney biopsy in Northwest China

Qin Y, Zhao J, Wei X, Wang Y, Yu Z, Zhang Y, Sun S

Background: The spectrum of biopsy-confirmed kidney disease varies with regions and periods. We describe the distribution of pathological types and epidemiological characteristics of kidney diseases in Northwest China due to...
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Association of CDKN2B-AS1 rs1333049 with Brain Diseases: A Case-control Study and a Meta-analysis

Zhao J, Wu X, Nie S, Gao X, Sun J, Li K, Zhang T, Huang Y

OBJECTIVE: CDKN2B-AS1 polymorphisms were shown to associate with the risk of stroke in European. The goal of this study was to evaluate the contribution of CDKN2B-AS1 rs1333049 to the risk...
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Cyclophosphamide-induced HCN1 channel upregulation in interstitial Cajal-like cells leads to bladder hyperactivity in mice

Liu Q, Long Z, Dong X, Zhang T, Zhao J, Sun B, Zhu J, Li J, Wang Q, Yang Z, Hu X, Li L

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are confirmed to be expressed in bladder interstitial Cajal-like cells (ICC-LCs), but little is known about their possible role in cystitis-associated bladder dysfunction. The present...
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Role of IFNLR1 gene in PRRSV infection of PAM cells

Qin M, Chen W, Li Z, Wang L, Ma L, Geng J, Zhang Y, Zhao J, Zeng Y

Background: Interferon lambda receptor 1 (IFNLR1) is a type II cytokine receptor that clings to interleukins IL-28A, IL29B, and IL-29 referred to as type III IFNs (IFN-λs). IFN-λs act through...
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Guangxi cobra venom-derived NGF promotes the osteogenic and therapeutic effects of porous BCP ceramic

Jin P, Yin F, Huang L, Zheng L, Zhao J, Zhang X

Neuro-osteological interactions have an important role in the regulation of bone metabolism and regeneration. Neuropeptides combined with porous biphasic calcium phosphates (BCP) using protein adsorption may contribute to the acceleration...
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