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Novel Compound Heterozygous Mutations in CTSC Gene in a Chinese Family with Papillon–Lefevre Syndrome

Wang Y, Zhang H, Feng S

Papillon–Lefevre syndrome (PLS) (OMIM: 245000) is a rare autosomal recessive disorder characterized by palmoplantar hyperkeratosis and early onset periodontitis, resulting in the premature loss of the deciduous and permanent teeth....
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The Role of miR-34c-5p in Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells

Liu B, Gan W, Jin Z, Wang M, Cui G, Zhang H, Wang H

Background and Objectives: Osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a critical role in the success of lumbar spinal fusion with autogenous bone graft. This study aims...
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Antinociceptive effects of oleuropein in experimental models of neuropathic pain in male rats

Chen H, Ma D, Zhang H, Tang Y, Wang J, Li R, Wen W, Zhang Y

Background: The present investigation explored the therapeutic actions of oleuropein along with the possible signaling pathway involved in attenuating neuropathic pain in chronic constriction injury (CCI) and vincristine-induced neuropathic pain...
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The Open Knowledge-Based Planning (OpenKBP) – An 2020 AAPM Grand Challenge: Sharing Experience and Achievement

Chun J, Hira S, Zhang H, Park JC, Kim H, Kim JS

  • KMID: 2510041
  • Prog Med Phys.
  • 2020 Sep;31(S1):S13.
Purpose: Knowledge-based planning (KBP) research is flourishing, but many results are reported using institution-specific datasets and evaluation metrics. While many competing approaches have reported positive results, comparing them is difficult...
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Disease Prevention Knowledge, Anxiety, and Professional Identity during COVID-19 Pandemic in Nursing Students in Zhengzhou, China

Sun Y, Wang D, Han Z, Gao J, Zhu S, Zhang H

Purpose: This study aimed to evaluate nursing students’ understanding of the prevention of COVID-19, as well as their anxiety towards the disease and their perception of their professional identity in...
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Overexpression of p21 Has Inhibitory Effect on Human Hematopoiesis by Blocking Generation of CD43+ Cells via Cell-Cycle Regulation

Zeng J, Zhang H, Liu Y, Sun W, Yi D, Zhu L, Zhang Y, Pan X, Chen Y, Zhou Y, Bian G, Lai M, Zhou Q, Liu J, Chen B, Ma F

Background and Objectives: p21, an important member of the Cip/Kip family, is involved in inhibitory effects of RUNX1b overexpression during the early stage of human hematopoiesis. Methods and Results: We established...
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Automatic Detection and Classification of Rib Fractures on Thoracic CT Using Convolutional Neural Network: Accuracy and Feasibility

Zhou QQ, Wang J, Tang W, Hu ZC, Xia ZY, Li XS, Zhang R, Yin X, Zhang B, Zhang H

Objective: To evaluate the performance of a convolutional neural network (CNN) model that can automatically detect and classify rib fractures, and output structured reports from computed tomography (CT) images. Materials and...
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SOCS1 Regulates the Immunomodulatory Roles of MSCs on B Cells

Zhang L, Qu YN, Zhang HY, Wu ZY, Li ZL, Guo WB, Wang QB, Fang NZ, Jiang XX

Background and Objectives: The effective use of MSCs for the treatment of some B cell-mediated immune diseases is quite limited. The main reason is that the immunomodulatory effects of mesenchymal...
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Association between Intracranial Arterial Dolichoectasia and Cerebral Small Vessel Disease and Its Underlying Mechanisms

Zhang DP, Yin S, Zhang HL, Li D, Song B, Liang JX

Intracranial arterial dolichoectasia (IADE), also known as dilatative arteriopathy of the brain vessels, refers to an increase in the length and diameter of at least one intracranial artery, and accounts...
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Surgical Outcomes of Dysphagia Provoked by Diffuse Idiopathic Skeletal Hyperostosis in the Cervical Spine

Chung YS, Zhang HY, Ha Y, Park JY

PURPOSE: This study aimed to predict the surgical outcomes of diffuse idiopathic skeletal hyperostosis (DISH)-related dysphagia (DISH-phagia) and to evaluate the importance of prevertebral soft tissue thickness (PVST). MATERIALS AND METHODS:...
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Use of Magnetic Resonance Neurography for Evaluating the Distribution and Patterns of Chronic Inflammatory Demyelinating Polyneuropathy

Su X, Kong X, Lu Z, Zhou M, Wang J, Liu X, Kong X, Zhang H, Zheng C

OBJECTIVE: To evaluate the distribution and characteristics of peripheral nerve abnormalities in chronic inflammatory demyelinating polyneuropathy (CIDP) using magnetic resonance neurography (MRN) and to examine the diagnostic efficiency. MATERIALS AND METHODS:...
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Review of Simultaneous Double Stenting Using Endoscopic Ultrasound-Guided Biliary Drainage Techniques in Combined Gastric Outlet and Biliary Obstructions

Zhang HC, Tamil M, Kukreja K, Singhal S

Concomitant malignant gastric outlet obstruction and biliary obstruction may occur in patients with advanced cancers affecting these anatomical regions. This scenario presents a unique challenge to the endoscopist in selecting...
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Imatinib and GNF-5 Exhibit an Inhibitory Effect on Growth of Hepatocellar Carcinoma Cells by Downregulating S-phase Kinase-associated Protein 2

Zhang H, Yi J, Yoon D, Ryoo Z, Lee I, Kim M

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is one of the leading causes of cancer-related deaths worldwide. Imatinib and GNF-5 are breakpoint cluster region-Abelson murine leukemia...
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Circ_0068655 Promotes Cardiomyocyte Apoptosis via miR-498/ PAWR Axis

Chai Q, Zheng M, Wang Z, We M, Yin Y, Ma F, Li X, Zhang H, Liu G

BACKGROUND: The cardiomyocyte apoptosis is considered as one of major contributions to cardiac remodeling after myocardial infarction (MI). Numerous studies find that circular RNAs (circRNAs) play pivotal roles in a...
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Contrast-enhanced ultrasound imaging features and clinical characteristics of combined hepatocellular cholangiocarcinoma: comparison with hepatocellular carcinoma and cholangiocarcinoma

Zhang HC, Zhu T, Hu RF, Wu L

Purpose: The purpose of this study was to retrospectively compare the clinical characteristics and imaging features on (CEUS) of combined hepatocellular cholangiocarcinoma (CHC) with those of hepatocellular carcinoma (HCC) and...
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Anterior Gradient 3 Promotes Breast Cancer Development and Chemotherapy Response

Xu Q, Shao Y, Zhang J, Zhang H, Zhao Y, Liu X, Guo Z, Chong W, Gu F, Ma Y

Purpose Anterior gradient 3 (AGR3) belongs to human anterior gradient (AGR) family. The function of AGR3 on cancer remains unknown. This research aimed to investigate if AGR3 had prognostic values in...
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Interaction between Brucella melitensis 16M and small ubiquitin-related modifier 1 and E2 conjugating enzyme 9 in mouse RAW264.7 macrophages

Yi J, Wang Y, Li Q, Zhang H, Shao Z, Deng X, He J, Xiao C, Wang Z, Wang Y, Chen C

Brucella is an intracellular pathogen that invades a host and settles in its immune cells; however, the mechanism of its intracellular survival is unclear. Modification of small ubiquitin-related modifier (SUMO)...
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Combination of Magnetic Resonance Spectroscopy and ¹¹C-Methionine Positron Emission Tomography for the Accurate Diagnosis of Non-Enhancing Supratentorial Glioma

Kudulaiti , Qiu T, Lu J, Zhang H, Zhang Z, Guan Y, Zhuang D, Wu J

OBJECTIVE: To evaluate whether the combination of magnetic resonance spectroscopy (MRS) and 11C-methionine positron emission tomography (11C-MET PET) could increase accurate diagnostic sensitivity for non-enhancing supratentorial gliomas. MATERIALS AND METHODS: Between...
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Relations between Stress and Quality of Life among Women in Late Pregnancy: The Parallel Mediating Role of Depressive Symptoms and Sleep Quality

Zhang H, Zhang Q, Gao T, Kong Y, Qin Z, Hu Y, Cao R, Mei S

OBJECTIVE: This study aims to examine the parallel multiple mediators of depressive symptoms and sleep quality in the relations between stress and physical health-related quality of life (PHQOL)/mental health-related quality...
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Changes in Trends of Spondylitis in Korea Based on a Nationwide Database

Noh SH, Zhang HY, Lee SH, Choi JK, Chin DK

No abstract available.
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