- Erratum: Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources
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Yun WB, Kim HR, Kim JE, Choi JY, Lee MR, Park JJ, Song BR, Jung YS, Song HK, Cho JY, Kim KS, Hwang DY
- KMID: 2402274
- Lab Anim Res.
- 2017 Dec;33(4):321-321.
- doi: 10.5625/lar.2017.33.4.321
One of the authors' names was misprinted. -
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- Overexpression of N141I PS2 increases γ-secretase activity through up-regulation of Presenilin and Pen-2 in brain mitochondria of NSE/hPS2m transgenic mice
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Yun WB, Park JJ, Kim JE, Sung JE, Lee HA, Lee JH, Bae CJ, Hwang DY
- KMID: 2362917
- Lab Anim Res.
- 2016 Dec;32(4):249-256.
- doi: 10.5625/lar.2016.32.4.249
Alzheimer's disease (AD) is known to induce alterations of mitochondrial function such as elevation of oxidative stress and activation of apopotosis. The aim of this study was to investigate the... -
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- Correlation between laxative effects of uridine and suppression of ER stress in loperamide induced constipated SD rats
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Kim JE, Song BR, Yun WB, Choi JY, Park JJ, Lee MR, Hwang DY
- KMID: 2402266
- Lab Anim Res.
- 2017 Dec;33(4):298-307.
- doi: 10.5625/lar.2017.33.4.298
A correlation between endoplasmic reticulum (ER) stress and laxative effects was first reported in a constipation model treated with an aqueous extract of Liriope platyphylla (AEtLP) roots. To investigate the... -
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- Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice
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Yun WB, Kim JE, Lee ML, Choi JY, Park JJ, Song BR, Kang BC, Nam KT, Lee HW, Hwang DY
- KMID: 2523774
- Lab Anim Res.
- 2021 Dec;37(4):294-306.
- doi: 10.1186/s42826-021-00107-y
Background: This study was undertaken to compare the sensitivities of mice strains during tumor induction by transcription activator-like effector nucleases (TALEN)-mediated Trp53 mutant gene. Alterations of their tumorigenic phenotypes including... -
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- The Association of APOE e4 Genotype With Cognition, Brain Volume, Glucose Metabolism, and Amyloid Deposition in AD
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Yun WB, Lee YM, Park JM, Lee BD, Moon E, Suh H, Kim K, Kim YJ, Lee H, Kim HJ, Park K, Choi KU
- KMID: 2542290
- J Korean Geriatr Psychiatry.
- 2023 Apr;27(1):30-36.
- doi: 10.47825/jkgp.2023.27.1.30
Objective: The purpose of this study is to investigate the association of the apolipoprotein E (APOE) e4 genotype with cognition, brain volume, glucose metabolism, and amyloid deposition in patients with... -
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- Laxative effects of Liriope platyphylla are tightly correlated with suppression of endoplasmic reticulum stress in loperamide-induced constipation of SD rats
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Kim JE, Go J, Sung JE, Lee HA, Seo EJ, Yun WB, Hwang DY
- KMID: 2312150
- Lab Anim Res.
- 2016 Mar;32(1):16-23.
- doi: 10.5625/lar.2016.32.1.16
A dysfunction of endoplasmic reticulum (ER) stress response can result in various diseases, including cancer, inflammation, diabetes and neurodegenerative disorders. To investigate whether ER stress response can play an essential... -
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- Comparison of therapeutic responses to an anticancer drug in three stocks of ICR mice derived from three different sources
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Sung JE, Kim JE, Lee HA, Yun WB, Choi JY, Lee MR, Park JJ, Kim HR, Song BR, Jung YS, Kim KS, Hwang DY
- KMID: 2407434
- Lab Anim Res.
- 2017 Jun;33(2):187-194.
- doi: 10.5625/lar.2017.33.2.187
Korl:ICR mice, established by the Korean National Institute of Food and Drug Safety Evaluation (NIFDS), are characterized based on their genetic variation, response to gastric injury, and response to constipation... -
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- Comparative study of fertilization rates of C57BL/6NKorl and C57BL/6N mice obtained from two other sources
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Yun WB, Kim HR, Kim JE, Choi JY, Lee MR, Park JJ, Song BR, Jung YS, Song HK, Cho JY, Kim KS, Hwang DY
- KMID: 2407433
- Lab Anim Res.
- 2017 Jun;33(2):179-186.
- doi: 10.5625/lar.2017.33.2.179
C57BL/6N is the most widely used inbred mouse strain applied in a wide variety of research areas including cancer, cardiovascular biology, developmental biology, diabetes and obesity, genetics, immunology, neurobiology, and... -
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- Characterization the response of Korl:ICR mice to loperamide induced constipation
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Kim JE, Yun WB, Sung JE, Lee HA, Choi JY, Choi YS, Jung YS, Kim KS, Hwang DY
- KMID: 2362915
- Lab Anim Res.
- 2016 Dec;32(4):231-240.
- doi: 10.5625/lar.2016.32.4.231
Animal models of constipation induced with drugs and diet have been widely employed to investigate therapeutic effects and the action mechanism of drugs against this disease. ICR mice were selected... -
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- Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats
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Lee MR, Kim JE, Yun WB, Choi JY, Park JJ, Kim HR, Song BR, Choi YW, Kim KM, Hwang DY
- KMID: 2391102
- Lab Anim Res.
- 2017 Sep;33(3):270-279.
- doi: 10.5625/lar.2017.33.3.270
Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts of the... -
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- Beneficial effect of diosgenin as a stimulator of NGF on the brain with neuronal damage induced by Aβ-42 accumulation and neurotoxicant injection
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Koh EK, Yun WB, Kim JE, Song SH, Sung JE, Lee HA, Seo EJ, Jee SW, Bae CJ, Hwang DY
- KMID: 2309084
- Lab Anim Res.
- 2016 Jun;32(2):105-115.
- doi: 10.5625/lar.2016.32.2.105
To investigate the beneficial effects of diosgenin (DG) on the multiple types of brain damage induced by Aβ-42 peptides and neurotoxicants, alterations in the specific aspects of brain functions were... -
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- Successful development of squamous cell carcinoma and hyperplasia in RGEN-mediated p27 KO mice after the treatment of DMBA and TPA
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Choi JY, Yun WB, Kim JE, Lee MR, Park JJ, Song BR, Kim HR, Park JW, Kang MJ, Kang BC, Lee HW, Hwang DY
- KMID: 2420824
- Lab Anim Res.
- 2018 Sep;34(3):118-125.
- doi: 10.5625/lar.2018.34.3.118
To evaluate the carcinogenicity of p27 knockout (KO) mice with RNA-guided endonuclease (RGENs)-mediated p27 mutant exon I gene (IΔ), alterations in the carcinogenic phenotypes including tumor spectrum, tumor suppressor proteins,... -
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- Therapeutic effect of ethyl acetate extract from Asparagus cochinchinensis on phthalic anhydride-induced skin inflammation
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Sung JE, Lee HA, Kim JE, Go J, Seo EJ, Yun WB, Kim DS, Son HJ, Lee CY, Lee HS, Hwang DY
- KMID: 2312152
- Lab Anim Res.
- 2016 Mar;32(1):34-45.
- doi: 10.5625/lar.2016.32.1.34
Asparagus cochinchinensis has been used to treat various diseases including fever, cough, kidney disease, breast cancer, inflammatory disease and brain disease, while IL-4 cytokine has been considered as key regulator... -
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- Hepatotoxicity and nephrotoxicity of saponin-enriched extract of Asparagus cochinchinensis in ICR mice
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Sung JE, Choi JY, Kim JE, Lee HA, Yun WB, Park JJ, Kim HR, Song BR, Kim DS, Lee CY, Lee HS, Lim Y, Hwang DY
- KMID: 2407417
- Lab Anim Res.
- 2017 Jun;33(2):57-67.
- doi: 10.5625/lar.2017.33.2.57
The inhibitory effects of Asparagus cochinchinensis against inflammatory response induced by lipopolysaccharide (LPS), substance P and phthalic anhydride (PA) treatment were recently reported for some cell lines and animal models.... -
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