- Reduced-intensity conditioning versus myeloablative conditioning allogeneic stem cell transplantation for patients with myelofibrosis
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Kim DH, Seo J, Shin DY, Koh Y, Hong J, Kim I, Yoon SS, Byun JM
- KMID: 2537549
- Blood Res.
- 2022 Dec;57(4):264-271.
- doi: 10.5045/br.2022.2022194
Background Allogeneic hematopoietic stem cell transplantation (alloSCT) is the sole curative option for myelofibrosis (MF). However, it is unknown as to which of the two, myeloablative conditioning (MAC) or reduced-intensity conditioning... -
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- Early diagnosis of Gaucher disease in Korean patients with unexplained splenomegaly: a multicenter observational study
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Do YR, Choi Y, Heo MH, Kim JS, Yoon Jh, Lee JH, Park JS, Sohn SK, Kim SH, Lim S, Chung JS, Jo DY, Eom HS, Kim H, Jeon SY, Won JH, Lee HJ, Shin JW, Jang JH, Yoon SS
- KMID: 2533248
- Blood Res.
- 2022 Sep;57(3):207-215.
- doi: 10.5045/br.2022.2022089
Background Gaucher disease (GD) is an autosomal recessive disorder characterized by excessive accumulation of glucosylceramide in multiple organs. This study was performed to determine the detection rate of GD in a... -
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- Peroxiredoxin 6 Overexpression Induces Anxiolytic and Depression-Like Behaviors by Regulating the Serotonergic Pathway in Mice
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Gu SM, Yu E, Kim YE, Yoon SS, Lee D, Hong JT, Yun J
- KMID: 2530998
- Biomol Ther.
- 2022 Jul;30(4):334-339.
- doi: 10.4062/biomolther.2021.169
Peroxiredoxin 6 (PRDX6) is a bifunctional protein with both glutathione peroxidase and calcium-independent phospholipase activity. Recently, we reported that PRDX6 plays an important role in dopaminergic neurodegeneration in Parkinson’s disease. However,... -
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- IDH1/2 mutations in acute myeloid leukemia
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Byun JM, Yoo SJ, Kim HJ, Ahn JS, Koh Y, Jang JH, Yoon SS
- KMID: 2527492
- Blood Res.
- 2022 Mar;57(1):13-19.
- doi: 10.5045/br.2021.2021152
The mutational and epigenetic landscape of acute myeloid leukemia (AML) has become increasingly well understood in recent years, informing on biological targets for precision medicine. Among the most notable findings... -
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- Eltrombopag for Post-Transplant Poor Graft Function in East Asian Patients
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Ahn HJ, Byun JM, Kim I, Youk J, Koh Y, Shin DY, Hong J, Yoon SS
- KMID: 2526036
- J Korean Med Sci.
- 2022 Feb;37(6):e48.
- doi: 10.3346/jkms.2022.37.e48
Poor graft function (PGF) is a serious, potentially life-threatening complication of allogeneic hematopoietic stem cell transplantation. Eltrombopag has shown multilineage responses in patients with refractory severe aplastic anemia, supporting the... -
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- The Effect of Formula-based Nutritional Treatment on Colitis in a Murine Model
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Jang S, Kim Y, Lee C, Kwon B, Noh J, Jee JJ, Yoon SS, Koh H, Park S
- KMID: 2523562
- J Korean Med Sci.
- 2021 Dec;36(50):e342.
- doi: 10.3346/jkms.2021.36.e342
Background: Exclusive enteral nutrition (EEN) induces remission in pediatric Crohn's disease (CD). The exact mechanism of EEN therapy in CD is unknown, but alteration of the intestinal microflora after EEN... -
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- Multicenter retrospective analysis of patients with chronic lymphocytic leukemia in Korea
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Yi JH, Lee GW, Lee JH, Yoo KH, Jung CW, Kim DS, Lee JO, Eom HS, Byun JM, Koh Y, Yoon SS, Kim JS, Kong JH, Yhim HY, Yang DH, Yoon DH, Lim DH, Lee WS, Shin HJ
- KMID: 2524074
- Blood Res.
- 2021 Dec;56(4):243-251.
- doi: 10.5045/br.2021.2021102
Background Chronic lymphocytic leukemia (CLL) is the most common type of adult leukemia in Western countries but is rare in the East Asian countries. Due to its rarity and the lack... -
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- Romiplostim plus danazol as salvage treatment for eltrombopag refractory immune thrombocytopenia: a retrospective pilot study
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Nam CH, Byun JM, Shin DY, Hong J, Kim I, Yoon SS, Koh Y
- KMID: 2520615
- Blood Res.
- 2021 Sep;56(3):202-204.
- doi: 10.5045/br.2021.2021067
No abstract available -
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- Recent Clinical Update of Acute Myeloid Leukemia: Focus on Epigenetic Therapies
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Lee E, Koh Y, Hong J, Eom HS, Yoon SS
- KMID: 2514759
- J Korean Med Sci.
- 2021 Apr;36(13):e85.
- doi: 10.3346/jkms.2021.36.e85
Acute myeloid leukemia (AML) is a complicated disease characterized by genetic heterogeneity and simultaneous alterations in multiple genes. For decades, its only curative method has been intensive induction chemotherapy with... -
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- Molecular and serological surveillance of equine piroplasmosis in the Republic of Korea between 2016 and 2017
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Seo HJ, Kim KH, Lee SK, Min S, Lim JY, Yang SJ, Yoo MS, Jung S, Yoon SS, Cho YS
- KMID: 2514727
- Korean J Vet Res.
- 2021 Mar;61(1):e4.
- doi: 10.14405/kjvr.2021.61.e4
Equine piroplasmosis (EP) is caused by Babesia caballi and Theileria equi infection. We investigated antigen and antibody of EP in horses in the Republic of Korea during 2016-2017. Antigen and... -
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- Single-nucleotide polymorphismbased epidemiological analysis of Korean Mycobacterium bovis isolates
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Kim TW, Jang YH, Jeong MK, Seo Y, Park CH, Kang S, Lee YJ, Choi JS, Yoon SS, Kim JM
- KMID: 2514470
- J Vet Sci.
- 2021 Mar;22(2):e24.
- doi: 10.4142/jvs.2021.22.e24
Background: Bovine tuberculosis (TB) is caused by Mycobacterium bovis, a well-known cause of zoonotic tuberculosis in cattle and deer, and has been investigated in many physiological and molecular studies. However,... -
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- Leukemic stem cell phenotype is associated with mutational profile in acute myeloid leukemia
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Han H, Byun JM, Shin DY, Yoon SS, Koh Y, Hong J, Kim I, Lee C, Yoo H, Yun H, Kim MJ, Cho SI, Seong MW, Park SS
- KMID: 2513751
- Korean J Intern Med.
- 2021 Mar;36(2):401-412.
- doi: 10.3904/kjim.2020.014
Background/Aims: Understanding leukemic stem cell (LSC) is important for acute myeloid leukemia (AML) treatment. However, association of LSC with patient prognosis and genetic information in AML patients is unclear. Methods: Here... -
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- Clinical Outcomes of Atypical Inflammatory Variants of Abdominal Aortic Aneurysm
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Cho J, Bang JH, Jeong SS, Yi J, Yoon SS, Cho K
- KMID: 2509406
- Korean J Thorac Cardiovasc Surg.
- 2020 Dec;53(6):353-360.
- doi: 10.5090/kjtcs.20.068
Background: Most abdominal aortic aneurysms are degenerative atherosclerotic aneurysms. Inflammatory or infected abdominal aortic aneurysms, which show a slightly different clinical course, are rarely encountered in clinical settings. Therefore, we... -
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- Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies
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Hong J, Park HK, Park S, Lee A, Lee YH, Shin DY, Koh Y, Choi JY, Yoon SS, Choi Y, Kim I
- KMID: 2505622
- Korean J Intern Med.
- 2020 Sep;35(5):1188-1198.
- doi: 10.3904/kjim.2018.469
Background/Aims: A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been... -
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- Synovial Cell Migration is Associated with B Cell Activating Factor Expression Increased by TNFα or Decreased by KR33426
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Lee J, Yoon SS, Thuy PX, Moon EY
- KMID: 2505685
- Biomol Ther.
- 2020 Sep;28(5):405-413.
- doi: 10.4062/biomolther.2020.110
Fibroblast-like synoviocytes (FLS) play a crucial role in initiating rheumatoid arthritis. B-cell activating factor (BAFF) plays a role in FLS survival as well as in B cell maturation and maintenance.... -
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- Seroprevalence and B1 gene Phylogeny of Toxoplasma gondii of Dogs and Cats in Republic of Korea
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Park Y, Noh J, Seo HJ, Kim KH, Min S, Yoo MS, Yun BR, Kim JH, Choi EJ, Cheon DS, Hong SJ, Yoon SS, Cho YS
- KMID: 2505093
- Korean J Parasitol.
- 2020 Jun;58(3):257-265.
- doi: 10.3347/kjp.2020.58.3.257
The outbreak of human toxoplasmosis can be attributed to ingestion of food contaminated with Toxoplasma gondii. Toxoplasmosis recently increased in domestic and stray dogs and cats. It prompted studies on... -
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- The predictive value of serum myeloma protein in solitary plasmacytoma
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Chang WI, Koh HK, Yoon SS, Kim HS, Eom KY, Kim IH
- KMID: 2503431
- Radiat Oncol J.
- 2020 Jun;38(2):129-137.
- doi: 10.3857/roj.2019.00570
Purpose: To identify the clinical usefulness of serum M protein and to establish a rationale for regular follow-up with serum protein electrophoresis in solitary plasmacytoma. Materials and Methods: Sixty-nine patients with... -
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- Imipramine Ameliorates Depressive Symptoms by Blocking Differential Alteration of Dendritic Spine Structure in Amygdala and Prefrontal Cortex of Chronic Stress-Induced Mice
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Leem YH, Yoon SS, Jo SA
- KMID: 2500499
- Biomol Ther.
- 2020 May;28(3):230-239.
- doi: 10.4062/biomolther.2019.152
Previous studies have shown disrupted synaptic plasticity and neural activity in depression. Such alteration is strongly associated with disrupted synaptic structures. Chronic stress has been known to induce changes in... -
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- Pathological, immunohistochemical, and bacteriological findings in dogs infected with Brucella canis
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Jung JY, Yoon SS, Lee S, Park JW, Lee J, Her M, So B, Kim JH
- KMID: 2506151
- Korean J Vet Res.
- 2020 Mar;60(1):9-14.
- doi: 10.14405/kjvr.2020.60.1.9
This study describes pathological, immunohistochemical, and bacteriological findings in adult dogs and fetuses naturally infected with Brucella (B) canis. A total of 42 dogs including 40 dogs and 2 aborted... -
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- Similar transplant outcomes between haploidentical and unrelated donors after reduced-intensity conditioning with busulfan, fludarabine, and anti-thymocyte globulin in patients with acute leukemia or myelodysplastic syndrome
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Choi M, Heo JY, Shin DY, Lee JY, Koh Y, Hong J, Kim I, Yoon SS, Lee JO, Bang SM
- KMID: 2472005
- Blood Res.
- 2020 Mar;55(1):27-34.
- doi: 10.5045/br.2020.55.1.27
BACKGROUND: Although T-cell-replete hematopoietic cell transplantation (HCT) from haploidentical donors (HIDs) using anti-thymocyte globulin (ATG) has shown promising outcomes, previous studies often adopted heterogenous graft sources and conditioning. METHODS: We retrospectively... -
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