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Genetic and Epigenetic Marker-Based DNA Test of Stool Is a Promising Approach for Colorectal Cancer Screening

An SW, Kim NK, Chung HC

Colorectal cancer (CRC) is one of the most common malignancies and leading cause of cancer-related deaths in the world. However, it may be treated effectively by surgical removal of the...
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A Case of Suspected Isotretinoin-Induced Malformation in a Baby of a Mother Who Became Pregnant One Month after Discontinuation of the Drug

Lee SM, Kim HM, Lee JS, Yoon CS, Park MS, Park KI, Namgung R, Lee C

Isotretinoin is a known human teratogen that can cause multiple malformations. At present, women who conceive one cycle after discontinuing isotretinoin are told that their teratogenic risk is not higher...
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A Case of Catecholaminergic Polymorphic Ventricular Tachycardia

Lee SY, Kim JB, Im E, Yang WI, Joung B, Lee MH, Kim SS

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial cardiac arrhythmia that is related to RYR2 or CASQ2 gene mutation. It occurs in patients with structurally normal heart and causes exercise-emotion-triggered...
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What Qualities Do Medical School Applicants Need to Have? : Secondary Publication

Hur Y, Kim S

PURPOSE: Doctors are asked to play the roles of both a healer and a professional. In dealing with this inherent demand, we should first ask ourselves if we are selecting...
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Epigenetic Regulation of Cytokine Gene Expression in T Lymphocytes

Lee CG, Sahoo A, Im SH

The developmental program of T helper and regulatory T cell lineage commitment is governed by both genetic and epigenetic mechanisms. The principal events, signaling pathways and the lineage determining factors...
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Promoter Methylation in the Genesis of Gastrointestinal Cancer

Boland CR, Shin SK, Goel A

Colorectal cancers (CRC)-and probably all cancers-are caused by alterations in genes. This includes activation of oncogenes and inactivation of tumor suppressor genes (TSGs). There are many ways to achieve these...
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Phenotypic Characterization of Ligamentum Flavum Cells from Patients with Ossification of Ligamentum Flavum

Zhong ZM, Chen JT

PURPOSE: The objective of this study was to determine the phenotypic characterization of ligamentum flavum cells from patients with ossification of the ligamentum flavum (OLF). MATERIALS AND METHODS: Ligamentum flavum...
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Characteristics of Glottic Closure Reflex in a Canine Model

Kim YH, Kang JW, Kim KM

PURPOSE: The most important function of the larynx is airway protection which is provided through a polysynaptic reflex closure triggered by the receptors in the glottic and supraglottic mucosa, evoking...
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Long-Surviving Patients with Recurrent GIST after Receiving Cytoreductive Surgery with Imatinib Therapy

Choi WH, Kim S, Hyung WJ, Yu JS, Park CI, Choi SH, Noh SH

In the treatment of recurrent or metastatic gastrointestinal stromal tumors (GIST), good prognoses may not be expected by surgery alone. Recently, imatinib has been applied for the treatment of GISTs,...
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Spontaneous Anterior Lens Capsular Dehiscence Causing Lens Particle Glaucoma

Kim TH, Kim SJ, Kim E, Chung IY, Park JM, Yoo JM, Song JK, Seo SW

To report acute onset lens particle glaucoma associated with a spontaneous anterior capsular dehiscence. A 66-year-old man presented with spontaneous anterior lens capsule dehiscence with an acute onset of right...
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Changes of Functional MRI Findings in a Patient Whose Pathological Gambling Improved with Fluvoxamine

Chung SK, You IH, Cho GH, Chung GH, Shin YC, Kim DJ, Choi SW

Legalized gambling is a growing industry, and is probably a factor in the presently increasing prevalence of pathological gambling. We present a case of a 36-year-old pathological gambler who was...
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Metallo-beta-Lactamase-Producing Pseudomonas spp. in Korea: High Prevalence of Isolates with VIM-2 Type and Emergence of Isolates with IMP-1 Type

Lee K, Park AJ, Kim MY, Lee HJ, Cho JH, Kang JO, Yong D, Chong Y

PURPOSE: Two Korean nationwide studies showed that metallo-beta-lactamases (MBLs)-producing-Pseudomonas spp. are not rare. The aim of this study was to assess the trends of MBL-producing isolates among imipenem-resistant isolates of...
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Correlation of Post Swim-Up Acrosome Index with in-vitro Fertilization Outcomes

Ozguner M, Evirgen O, Oral B

PURPOSE: A prospective study was planned to determine the relationship between post swim-up acrosome index (AI) evaluation and fertilization outcomes in an in vitro fertilization (IVF) program. MATERIALS AND METHODS:...
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Influence of Gender on Serum Growth Hormone, Insulin-Like Growth Factor-I and Its Binding Protein-3 during Aging

Lin CM, Huang YL, Lin ZY

PURPOSE: The serum concentrations of insulin-like growth factors-I (IGF-I), insulin-like growth factor binding protein-3 (IGFBP-3) and growth hormone (GH) are related to body composition, function and metabolism, and are influenced...
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Analysis of Rating Appropriateness and Patient Outcomes in Cataract Surgery

Choi YJ, Park EC

PURPOSE: Using the RAND/UCLA methodology to create the appropriateness criteria, we assessed that the appropriate ratings in cataract surgery can be a better prognosis of outcomes in postoperative 12 months...
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Preventive Effects of Oligomerized Polyphenol on Estradiol-Induced Prostatitis in Rats

Kim DS, Lee EJ, Cho KS, Yoon SJ, Lee YH, Hong SJ

PURPOSE: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS, NIH category III) accounts for 90-95% of prostatitis cases. However, standard treatment has not yet been established. It is known that polyphenols have...
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Phase Contrast Microradiography of Mouse Lung Using Synchrotron X-ray: Correlation with Optical Microscopy

Yong HS, Kang EY, Kim YK, Woo OH, Shin BK, Oh CH, Je JH, Han H, Seo JS

PURPOSE: The purpose of this study is to evaluate the feasibility of phase contrast X-ray microtomography and microradiography, using a polychromatic synchrotron X-ray, for analysis of the mouse lung microstructure....
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Expression of Heat Shock Protein 60 kDa Is Upregulated in Cervical Cancer

Hwang YJ, Lee SP, Kim SY, Choi YH, Kim MJ, Lee CH, Lee JY, Kim DY

PURPOSE: Cervical cancer caused by the human papilloma virus (HPV) continues to be the cause of yearly death among women. However, it is a curable disease when diagnosed at an...
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The Influence of Weight and Height Status on Psychological Problems of Elementary Schoolchildren through Child Behavior Checklist Analysis

Kim B, Park MJ

PURPOSE: This study aimed to evaluate weight and height status and their relationship with psychological problems among elementary schoolchildren. MATERIALS AND METHODS: A total of 405 schoolchildren (211 boys and...
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Inhibitory Effect of Fentanyl on Phenylephrine-Induced Contraction of the Rat Aorta

Park KE, Sohn JT, Jeong YS, Sung HJ, Shin IW, Lee HK, Chung YK

PURPOSE: Fentanyl was reported to inhibit the alpha1-adrenoceptor agonist-induced contraction. The goal of this in vitro study was to identify the alpha1-adrenoceptor subtype primarily involved in the fentanyl-induced attenuation of...
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