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Embryological background for fetal surgery

Park HW

Congenital malformations are one of the main topics, which must be addressed in the 21st century. Fetal surgery is expected to become a routine procedure for malformed fetal patients in...
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Diagnosis of fetal anomalies by sonography

Park YW

The last 2 decades have seen considerable advances in obstetric ultrasonography, which now forms part of routine prenatal care in most countries. Congenital anomalies often occur sporadically and unpredictably. The...
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The fetal wound healing: a review

Roh TS, Rah DK, Park BY

Fetal wound healing has drawn the attention of many researchers from diverse background and specialties. Fetal wound healing is unique and differs from postnatal healing in that fetal skin wounds...
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The role of fetal surgery in life threatening anomalies

Choi SH

The development and evolution of fetal surgery and the recognition of the fetus as a patient came from two sources. First, were those obstetricians and perinatologists who detected life threatening...
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The development of fetal surgery

Han SJ, Hwang EH

The history of fetal surgery features an absolute dependency upon the possibility of diagnosis before birth. Powerful new imaging methods, the techniques of sampling amniotic fluid and fetal tissue, and...
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In utero hematopoietic stem cell therapy

Hayashi S, Flake AW

In utero hematopoietic stem cell transplantation (IUHSCTx) is a promising approach for the treatment of a potentially large number of fetuses affected by congenital hematologic disorders. With technical advances in...
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Comparative study on motility of the cultured fetal and neonatal dermal fibroblasts in extracellular matrix

Park JC, Park BJ, Suh H, Park BY, Rah DK

One of the differences between fetal and adult skin healing is the ability of fetal wounds heal without contraction and scar formation. Extracellular matrix (ECM) provides a substratum for cells...
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Fetal surgery for congenital heart disease

Park HK, Park YH

Certain congenital heart defects, which present at birth as complex morphologic defects, are actually the result of a relatively simple primary lesion and the subsequent acquired development of a complex...
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The subcutaneous capsules for foreign body in fetal rabbits: preliminary report

Lee WJ, Park BY

In terms of wound healing, there are fundamental intrinsic and extrinsic differences between fetuses (scar-free healing) and adults. The fetus exhibits less typical inflammatory response (signifiquently neutropenic) with an underdeveloped...
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Gene therapy of scarring: a lesson learned from fetal scarless wound healing

Liu W, Cao Y, Longaker M

Cutaneous wounding in adult humans and higher vertebrate animals results in scar formation. In contrast, both human and animal fetuses, at early gestational ages, exhibit skin wound healing without scarring....
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Endoscopic techniques in fetal surgery

Sydorak RM, Nijagal A, Albanese C

Fetal endoscopic surgery (FETENDO) involves many techniques that allow surgical procedures to be performed inside the uterus without an hysterotomy. The impetus for developing these minimal access techniques for fetal...
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Comparison of bone morphogenetic protein receptors expression in the fetal and adult skin

Hwang EA, Lee HB, Tark KC

Wounds on fetal skin can be repaired without leaving scars until the second trimester, but after this period, skin wounds leave scars as in adults. It's known that certain growth...
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The pathogenesis of craniosynostosis in the fetus

Warren SM, Longaker M

Craniosynostosis occurs in approximately 1:2000 live births. It may affect the coronal, sagittal, metopic and lambdoid sutures in isolation or in combination. Although non-syndromic synostoses are more common, over 150...
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Anesthesia for fetal procedures and surgery

Rosen MA

Many of the anesthetic considerations for fetal procedures and surgery are identical to those for nonobstetric surgery during pregnancy, including concern for maternal safety, avoidance of both teratogenic drugs and...
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