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Gene Therapy of Cancer by the Inhibition of Transcription and Expression

Hwang PH, Yi HK

  • KMID: 1535329
  • Korean J Pediatr Hematol Oncol.
  • 1998 Oct;5(2):250-259.
No abstract available.
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Erratum: Addition of Co-Authors: Up-regulation of IGF Binding Protein-3 Inhibits Colonic Inflammatory Response

Kim SC, Kim SY, Yi HK, Hwang PH

The authors regret that two co-authors were missing in the article.
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A Case of Neonatal Diabetes Mellitus: Transient or Permanent?

Lee DY, Yi HK, Hwang PH

  • KMID: 2001527
  • J Korean Soc Pediatr Endocrinol.
  • 2000 Dec;5(2):210-214.
A case of neonatal diabetes mellitus is described. The child presented with low birth weight but was normal in appearance. She was acidotic and ketonuria was observed. The HLA typing...
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The Outcomes of Curative Surgery for Primary Duodenal Malignancy

Yi HK, Park KM, Jeon HB, Lee YJ, Hwang S, Lee SG

  • KMID: 2095349
  • J Korean Surg Soc.
  • 1998 Apr;54(4):531-535.
Fifteen cases of the primary duodenal malignancies were radically resected from July 1989 to September 1996. These cases were analysed retrospectively with the literature review. The male to female ratio...
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Novel Gap Junction Molecules, Connexin 37, Enhances the Bystander Effect in HSVtk/GCV Gene Therapy

Kim SY, Yi HK, Lee JC, Hwang DJ, Hwang PH, Lee DY, Cho SC

  • KMID: 1606818
  • J Korean Pediatr Soc.
  • 2003 Jun;46(6):541-547.
PURPOSE: Gap junction intercellular communication(GJIC) is an important mechanism of the bystander effect in herpes simplex thymidine kinase/ganciclovir(HSVtk/GCV) gene therapy Therefore, we attempted to enhance the bystander effect in vitro...
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Workers' Compensation Insurance and Occupational Injuries

Shin I, Oh JB, Yi HK

  • KMID: 2317010
  • Saf Health Work.
  • 2011 Jun;2(2):148-157.
OBJECTIVES: Although compensation for occupational injuries and diseases is guaranteed in almost all nations, countries vary greatly with respect to how they organize workers' compensation systems. In this paper, we...
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A Case of Wiskott-Aldrich Syndrome with Novel Mutation in Exon 2 of the WASP Gene

Lee H, Park JI, Kim SY, Moon KH, Yi HK, Hwang PH

  • KMID: 2278632
  • Korean J Pediatr.
  • 2005 May;48(5):551-556.
Wiskott-Aldrich syndrome(WAS) is an X-linked recessive immunodeficiency characterized by thrombocytopenia with small platelet volume, eczema, and recurrent infections, and is also characterized by increased incidence of auto immune diseases and...
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Molecular Genetic Analysis of Cis-AB with Cytosine at nucleotide position 467

Kim DS, Lee HS, Choi SI, Hwang PH, Yi HK

  • KMID: 1838434
  • J Korean Soc Microbiol.
  • 1999 Feb;34(1):13-20.
BACKGROUNDS: The molecular genetic characteristcs of cis-AB blood group have shown that its allele had C, G, C and C at nucleotide positions (nps) 526, 703, 796 and 803, respectively....
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Phelligridin D maintains the function of periodontal ligament cells through autophagy in glucose-induced oxidative stress

Kim JE, Kim TG, Lee YH, Yi HK

Purpose: The objective of this study was to investigate whether phelligridin D could reduce glucose-induced oxidative stress, attenuate the resulting inflammatory response, and restore the function of human periodontal ligament...
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The Change of Serum Insulin-Like Growth Factor Binding Protein 3 (IGFBP-3) in the Diagnosis and Management of Prostate Cancer

Kim HJ, Hwang PH, Yi HK, Youm JH, Lee DY

  • KMID: 1884994
  • Korean J Urol.
  • 2001 Jul;42(7):713-717.
PURPOSE: Insulin-like growth factor binding protein 3 (IGFBP-3) binds to IGF and acid labile subunit in blood, that regulates the action of IGF by modulating the interaction of IGF with...
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Molecular Genetic Analysis of Cis-AB with Cytosine at nucleotide position 467

Kim DS, Lee HS, Choi SI, Hwang PH, Yi HK

  • KMID: 1862937
  • Korean J Blood Transfus.
  • 1999 May;10(1):13-19.
BACKGROUNDS: The molecular genetic characteristcs of cis-AB blood group have shown that its allele had C, G, C and C at nucleotide positions (nps) 526, 703, 796 and 803, respectively....
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Apoptotic Pathway Induced by Dominant Negative ATM Gene in CT-26 Colon Cancer Cells

Lee JC, Yi HK, Kim SY, Lee DY, Hwang PH, Park JW

  • KMID: 2335743
  • J Korean Pediatr Soc.
  • 2003 Jul;46(7):679-686.
PURPOSE: Ataxia telangiectasia mutated(ATM) is involved in DNA damage responses at different cell cycle checkpoints, and signalling pathways associated with regulation of apoptosis in response to ionizing radiation(IR). However, the...
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The anti-tumor mechanisms of p53 through the regulation of expression and glycosylation of insulin-like growth factor binding protein-3

Kim SY, Kim SR, Lee JC, Yi HK, Lee DY, Hwang PH

PURPOSE: Insulin-like growth factor binding protein(IGFBP)-3 has been known as a tumor suppressor gene, and its anti-tumor function was divided into insulin-like growth factor(IGF)-dependent and IGF-independent mechanism. In IGF-independent mechanism,...
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PPARgamma Inhibits Inflammation through the Suppression of ERK1/2 Kinase Activity in Human Gingival Fibroblasts

Lee YH, Kwak DH, Kang MS, Bhattarai , Lee NH, Jhee EC, Yi HK

  • KMID: 1719930
  • Int J Oral Biol.
  • 2010 Mar;35(1):27-33.
Periodontal disease is a major oral disorder and comprises a group of infections that lead to inflammation of the gingiva and the destruction of periodontal tissues. PPARgamma plays an important...
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Effects of Cefodizime on Phagocytosis of COS-1 Ccells

Hwang PH, Nam SY, Yi HK, Kim MH, Kim KS, Kim JS

  • KMID: 2104441
  • J Korean Pediatr Soc.
  • 1998 Dec;41(12):1632-1638.
PURPOSE: Cefodizime is a new third-generation cephalosporin which has a structure and immunomodutation properties similar to cefotaxime. Various studies on cefodizime have demonstrated the direct eradication of bacteria in cooperation...
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Survival, Differentiation and ATM Phenotype of PC-12 Cells by Down - regulation of AT Gene

Yi HK, Chang SH, Lee DY, Kim JS, Hwang PH

  • KMID: 2059305
  • J Korean Cancer Assoc.
  • 1999 Oct;31(5):1065-1073.
PURPOSE: Ataxia Telangiectasia (AT) is a hereditary multi-systemic disease resulting from mutations of AT gene and is characterized by progressive neurodegeneration, cancer, immune system defects, and hypersensitivity to ionizing radiation....
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Induction of Apoptosis of Ewing's Sarcoma Cells by Regulating Fusion Protein Expression

Yi HK, Kim RJ, Kim JS, Hwang PH

  • KMID: 2335496
  • J Korean Pediatr Soc.
  • 2000 Jul;43(7):942-951.
PURPOSE: Fusion genes(EWS-Fli-1 and EW.S-erg) function as transcription activators and are essential for maintaining tumorigenic properties in Ewing's sarcoma cells. Several reports have noted that Ets family transcription factors bind with CBP(CREB...
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Changes in the expression of cytokines and apoptosis-related genes in children with infectious mononucleosis

Jo DS, Han JH, Kim SY, Kim MS, Yi HK, Lee DY, Hwang PH

PURPOSE: The aims of this study were to identify the clinical characteristics and determine the changes in the expression of cytokines and apoptosis-related genes in children with infectious mononucleosis. METHODS:...
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Induction of Apoptosis in Head and Neck Cancer Cells by Dominant Negative C-myb Gene Therapy

Hwang PH, Yoon HW, Park MY, Yang YS, Yi HK, Lee DY, Hong KH

  • KMID: 1215296
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Aug;46(8):677-685.
BACKGROUND AND OBJECTIVES: Although the role of c-myb in head and neck tumor has not been studied, aberrant expression of c-myb in various cancer has been demonstrated recently, suggesting that...
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Studies on Functional Differentiation of Small Intestinal Epithelial Cells

Yi HK, Oh SM, Lee DY, Kim JS, Hwang PH

  • KMID: 2207443
  • J Korean Pediatr Soc.
  • 2001 May;44(5):523-532.
PURPOSE: We investigated compounds from food sources given to children that may induce the differentiation of small intestinal epithelial cells in order to signal pathways that induce the prolif eration and...
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