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Treatment with biological products for chronic urticaria

Ye YM

Background: Chronic urticaria is characterized by repeatedly occurring itchy wheals and/or angioedema for at least six weeks. The prevalence of chronic urticaria is increasing globally, with variations observed among different...
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Effects of COVID-19 and Influenza Vaccination on Rheumatic Diseases: Results From a Survey of PatientReported Outcomes After Vaccination

Kim JW, Jung JY, Suh CH, Ye YM, Kim HA

Background: This study aimed to compare the occurrence of adverse events (AEs) and disease flares after vaccination against coronavirus disease 2019 (COVID-19) and influenza in patients with autoimmune rheumatic diseases...
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The burden of symptomatic patients with chronic spontaneous urticaria: a real-world study in Korea

Ye YM, Koh YI, Choi JH, Kim MA, Park JW, Kim TB, Nam YH, Chang YS, Park HS

Background/Aims: Chronic spontaneous urticaria (CSU) poses a considerable burden both on the quality of life (QoL) of individual patients and on healthcare systems. Real‑world data evaluating the disease burden of...
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Hypersensitivity to Anticonvulsants

Ye YM

  • KMID: 2534635
  • J Pharmacoepidemiol Risk Manage.
  • 2020 Sep;12(2):57-62.
Hypersensitivity reactions due to antiepileptics are rare but potentially fatal reactions associated most commonly with carbamazepine, phenytoin, and lamotrigine. Drug hypersensitivity to antiepileptics generally occurs on first exposure to the...
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Health-Related Utility of EQ-5D in Korean Adults With Chronic Urticaria: Mapping From Urticaria Outcome Measures

Lee MS, Yoon J, Kim J, Shin YS, Park HS, Lee HY, Ye YM

Purpose: A need for useful measures reflective of the socio-economic burden of chronic urticaria (CU) has arisen. To obtain utility estimates for CU, we investigated EuroQol-5-Dimension (EQ-5D) indices according to...
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The KAAACI/KDA Evidence-Based Practice Guidelines for Chronic Spontaneous Urticaria in Korean Adults and Children: Part 1. Definition, Methodology and First-line Management

Song WJ, Choi M, Lee DH, Kwon JW, Kim GW, Kim MH, Kim MA, Kim MH, Kim BK, Kim S, Kim JS, Kim JE, Kim JY, Kim JH, Kim HJ, Kim HO, Kim HB, Roh JY, Park KH, Park KY, Park HK, Park H, Bae JM, Byun JY, Song DJ, Ahn YM, Lee SE, Lee YB, Lee JS, Lee JH, Lim KH, Ye YM, Chang YS, Jeon YH, Jeon J, Jue MS, Choi SH, Choi JH, Hur GY, Park YM, Lim DH, Youn SW

Chronic spontaneous urticaria (CSU) is defined as the occurrence of spontaneous wheals, angioedema, or both for >6 weeks in the absence of specific causes. It is a common condition associated...
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Serum potential biomarkers according to sputum inflammatory cell profiles in adult asthmatics

Hur GY, Ye YM, Yang E, Park HS

Background/Aims: Asthma is not a single disease but, rather, a heterogeneous inf lammatory disorder with various pathogenic mechanisms. We analyzed the associations between the cellular profile of sputum and the...
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A Prospective Observation of Psychological Distress in Patients With Anaphylaxis

Lee Y, Chang HY, Kim SH, Yang MS, Koh YI, Kang HR, Choi JH, Kim CW, Park HK, Kim JH, Nam YH, Kim TB, Hur GY, Jung JW, Park KH, Kim MA, Kim J, Yoon J, Ye YM

PURPOSE: Anaphylaxis is an immediate allergic reaction characterized by potentially life-threatening, severe, systemic manifestations. While studies have evaluated links between serious illness and posttraumatic stress disorder (PTSD), few have investigated...
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Increasing Prevalence and Mortality of Asthma With Age in Korea, 2002–2015: A Nationwide, Population-Based Study

Lee E, Kim A, Ye YM, Choi SE, Park HS

PURPOSE: The prevalence of asthma is increasing globally as the world population increases; however, and the prevalence and mortality of asthma have not been extensively investigated. Also, the effects of...
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Efficacy and Safety of a Pressurized Metered-Dose Inhaler in Older Asthmatics: Comparison to a Dry Powder Inhaler in a 12-Week Randomized Trial

Woo SD, Ye YM, Lee Y, Lee SH, Shin YS, Park JH, Choi H, Lee HY, Shin HJ, Park HS

PURPOSE: Asthma control in older asthmatics is often less effective, which may be attributed to small airway dysfunction and poor inhalation technique. We compared the efficacy of 2 inhalers (fluticasone...
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Causes of food allergy according to age and severity: A recent 10-year retrospective study from a single tertiary hospital

Lee E, Jeong K, Shin YS, Nahm DH, Park HS, Choi HN, Yoon J, Ye YM, Lee S

Purpose: Recent studies of food allergy (FA) at all ages are scanty in Korea. We performed this study to better understand severity-related and age-stratified causes of FA from infants to...
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Non-episodic Angioedema With Eosinophilia Successfully Treated With Reslizumab

Chu H, Youn DY, Park HS, Ye YM, Park YB, Ban GY

No abstract available.
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Safety of Ultra-rush Schedule of Subcutaneous Allergen Immunotherapy With House Dust Mite Extract Conducted in an Outpatient Clinic in Patients With Atopic Dermatitis and Allergic Rhinitis

Lee SH, Kim ME, Shin YS, Ye YM, Park HS, Nahm DH

PURPOSE: Ultra-rush schedule of subcutaneous allergen immunotherapy (UR-SCIT) administering maximum maintenance dose of allergen extract within one day can save time and effort for allergen immunotherapy in patients with allergic...
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Severe Cutaneous Adverse Reactions to Antiepileptic Drugs: A Nationwide Registry-Based Study in Korea

Park CS, Kang DY, Kang MG, Kim S, Ye YM, Kim SH, Park HK, Park JW, Nam YH, Yang MS, Jee YK, Jung JW, Kim SH, Kim CW, Kim MY, Kim JH, Lee J, Lee JG, Kim SH, La HO, Kim MH, Park SJ, Koh YI, Lee SM, Kwon YE, Jin HJ, Kim HK, Kang HR, Choi JH, Korean Registry of Severe Cutaneous Adverse Reactions Consortium

PURPOSE: Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) to antiepileptic drug (AED), are rare, but...
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Urticaria: Classification and Diagnosis

Ye YM

Urticaria is a common cutaneous disease characterized by recurrent and transient wheals and pruritus, sometimes accompanied angioedema. The classification of urticaria is based on the duration of the disease and...
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Dimerized, Not Monomeric, Translationally Controlled Tumor Protein Induces Basophil Activation and Mast Cell Degranulation in Chronic Urticaria

Ulambayar , Lee H, Yang EM, Park HS, Lee K, Ye YM

Translationally controlled tumor protein (TCTP) is also known as histamine releasing factor as it has the ability to activate mast cells. To investigate the role of TCTP in the pathogenesis...
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Factors Associated with Adherence to Allergen Specific Subcutaneous Immunotherapy

Lee JH, Lee SH, Ban GY, Ye YM, Nahm DH, Park HS, Shin YS

PURPOSE: Allergen-specific immunotherapy (AIT) is known to be the only therapeutic modality to alter the natural course of allergic diseases. However, at least 3 years of treatment is recommended for...
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Trabecular Bone Score Is More Sensitive to Asthma Severity and Glucocorticoid Treatment Than Bone Mineral Density in Asthmatics

Choi YJ, Lee HY, Yoon D, Kim A, Shin YS, Park HS, Ye YM

PURPOSE: In asthmatic patients, treatment with corticosteroids, in addition to conventional risk factors for osteoporosis, may lead to bone loss. Trabecular bone score (TBS) is an indirect new parameter of...
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Phenotypes of Severe Cutaneous Adverse Reactions Caused by Nonsteroidal Anti-inflammatory Drugs

Lee SY, Nam YH, Koh YI, Kim SH, Kim S, Kang HR, Kim MH, Lee JG, Park JW, Park HK, La HO, Kim MY, Park SJ, Kwon YE, Jung JW, Kim SH, Kim CW, Yang MS, Kang MG, Lee JY, Kim JH, Kim SH, Hur GY, Jee YK, Jin HJ, Park CS, Jeong YY, Ye YM

PURPOSE: Nonsteroidal anti-inflammatory drugs (NSAIDs) are common cause of severe cutaneous adverse reactions (SCARs). The present study aimed to investigate the characteristics of SCARs induced by NSAIDs in the Korean...
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Association Between Epithelial Cytokines and Clinical Phenotypes of Elderly Asthma

Ulambayar , Lee SH, Yang EM, Ye YM, Park HS

PURPOSE: Asthma in the elderly has different clinical features including more severe phenotypes with higher comorbidities. Epithelial cells are known to initiate innate/adaptive immune responses in asthmatic airways. We investigated...
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