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Asian Subgroup Analysis of the REMISSIO Study: A Long-Term Efficacy and Safety Study of Paliperidone Palmitate 3-month Formulation in Patients with Stable Schizophrenia in a Naturalistic Clinical Setting

Chung YC, Yang YK, Sulaiman AH, Bergmans P, Tan W

Objective: To evaluate the long-term efficacy and safety of three-monthly paliperidone palmitate (PP3M) in Asian patients with stable schizophrenia in a naturalistic setting. Methods: Asian patients recruited between May 2016 and...
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Serotonin Modulates the Correlations between Obsessive-compulsive Trait and Heart Rate Variability in Normal Healthy Subjects: A SPECT Study with [ 123 I]ADAM and Heart Rate Variability Measurement

Kuo CY, Chen KC, Lee IH, Tseng HH, Chiu NT, Chen PS, Yang YK, Chang WH

Objective: The impact of serotonergic system on obsessive-compulsive disorder (OCD) is well studied. However, the correlation between OC presentations and autonomic nervous system (ANS) is still unclear. Furthermore, whether the...
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Central Pontine Myelinolysis in a Normonatremic Patient with Depression

Liu YC, Yang YK, Chen PS, Chang WH

A 76-year-old male presented with a recurrent depressive episode, an unsteady gait and cognitive impairment. Extensive blood tests, including hemogram, biochemical tests, folic acid, vitamin B12, and thyroid hormone, showed...
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Positive Symptoms in Antipsychotic-naïve Schizophrenia are Associated with Increased Body Mass Index after Treatment

Lin SH, Tseng HH, Tsai HC, Chi MH, Lee IH, Chen PS, Chen KC, Yang YK

Objective: Weight gain is an important risk factor for morbidity and mortality among patients with schizophrenia. We speculated that positive symptoms, related to dopaminergic hyperactivity and altered mesolimbic function, are...
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Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder

Lu RB, Chang YH, Lee SY, Wang TY, Cheng SL, Chen PS, Yang YK, Hong JS, Chen SL

Objective: Valproic acid (VPA) is an anticonvulsant and commonly long term used as a mood stabilizer for patients with mood disorders. However its chronic effects on the hematological changes were...
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ALDH2 Gene: Its Effects on the Neuropsychological Functions in Patients with Opioid Use Disorder Undergoing Methadone Maintenance Treatment

Lee PW, Wang TY, Chang YH, Lee SY, Chen SL, Wang ZC, Chen PS, Chu CH, Huang SY, Tzeng NS, Lee IH, Chen KC, Yang YK, Hong JS, Lu RB

Objective: Patients with opioid use disorder (OUD) have impaired attention, inhibition control, and memory function. The aldehyde dehydrogenase 2 (ALDH2 ) gene has been associated with OUD and ALDH2 gene...
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Altered Auditory P300 Performance in Parents with Attention Deficit Hyperactivity Disorder Offspring

Chi MH, Chu CL, Lee IH, Hsieh YT, Chen KC, Chen PS, Yang YK

OBJECTIVE: Altered event-related potential (ERP) performances have been noted in attention deficit hyperactivity disorder (ADHD) patients and reflect neurocognitive dysfunction. Whether these ERP alterations and correlated dysfunctions exist in healthy...
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The Interaction of Oxytocin and Social Support, Loneliness, and Cortisol Level in Major Depression

Tsai TY, Tseng HH, Chi MH, Chang HH, Wu CK, Yang YK, Chen PS

OBJECTIVE: Loneliness is a specific risk factor for depressive symptoms and suicidal behavior. The present study examined whether the serum oxytocin level would interact with social support and buffers loneliness...
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Factors Influencing Safety Care Activities of Hospital Nurses

Yang YK

PURPOSE: The purpose of this study was to investigate the relationships among fatigue, patient safety culture and safety care activities of hospital nurses, and to identify and explain factors influencing...
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Psychometric Properties of the Korean Version of the Tromsø Social Intelligence Scale

Park SK, Yang YK, Song E

PURPOSE: The purpose of this study was to translate Tromsø Social Intelligence Scale (TSIS) into Korean and verify the validity and reliability of the Korean version of the TSIS. METHODS: This...
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Influencing Factors on Breastfeeding Nursing Activities of Nursing Students

Yang YK

PURPOSE: This study was conducted to examine the relationships among knowledge, attitudes and nursing activities while breastfeeding among nursing students, and to identify factors influencing nursing activities in breastfeeding. METHODS: The...
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Social Disaster Adaptation Experiences of Railroad Workers: Focused on the Iri Station Explosion of 1977

Jung HG, Yang YK

PURPOSE: The Iri station explosion that occurred in 1977 was a major social disaster in Korea, caused by a fire in a train equipped with explosives. The purpose of this...
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Increased Readmission Risk and Healthcare Cost for Delirium Patients without Immediate Hospitalization in the Emergency Department

Ma IC, Chen KC, Chen WT, Tsai HC, Su CC, Lu RB, Chen PS, Chang WH, Yang YK

OBJECTIVE: Hospitalization of patients with delirium after visiting the emergency department (ED) is often required. However, the readmission risk after discharge from the ED should also be considered. This study...
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Influences of Participation Motivation and Satisfaction of Nursing Students on Continuance Willingness of Voluntary Activities

Yang YK

PURPOSE: This study was done to examine the relationship between participation motivation, satisfaction and continuance willingness of voluntary activities of nursing students, and to identify factors influencing continuance willingness of...
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Anaphylaxis after rocuronium administration during induction of anesthesia

Kim JE, Yang YK, Kwon MY

Anaphylaxis during anesthesia is rare, but often fatal. Rocuronium is a neuromuscular relaxant used for induction of anesthesia. We experienced a case of anaphylaxis after rocuronium administration during induction of...
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Influences of Communication Skill and Interpersonal Ability on Clinical Competence of Nursing Students

Yang YK

PURPOSE: This study was done to examine the relationship between communication skill, interpersonal ability and clinical competence of nursing students, and to identify factors influencing clinical competence. METHODS: Research participants were...
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Difficult intubation of a patient with progressive multifocal leukoencephalopathy and muscle spasticity: A case report

Kim JE, Yang YK, Kwon MY, Yun MJ, Kim GH

Progressive multifocal leukoencephalopathy (PML) is a demyelinating central nervous system disease characterized by neurological deficits, including cognitive impairment, altered mental status, and muscle spasticity. Preoperative evaluation and intraoperative airway management...
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Hospital Nurses' Experiences of Conflict and Conflict Resolution

Jung HG, Yang YK

PURPOSE: The purpose of this study was to investigate conflicts and the experiences of conflict resolution of hospital nurses. METHODS: This qualitative study used phenomenological methodology. The research participants were 8...
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Mediating Effect of Communication Skill in the Relationship between Fatigue and Clinical Practice Stress in Nursing Students

Yang YK

PURPOSE: Fatigue and clinical practice stress can negatively influence nursing students. This study was done to examine of communication skill as mediating effect variable in the relationship between fatigue and...
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Effects on Critical Thinking Disposition and Empathy on Cultural Competency in Nursing Students

Song EJ, Yang YK, Park SK

PURPOSE: This study was conducted to investigate the effects of critical thinking disposition and empathy on cultural competency in nursing students. METHODS: The participants were 199 nursing students from D, H,...
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