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Evolution of Radiological Treatment Response Assessments for Cancer Immunotherapy: From iRECIST to Radiomics and Artificial Intelligence

Kim N, Lee ES, Won SE, Yang M, Lee AJ, Shin Y, Ko Y, Pyo J, Park HJ, Kim KW

Immunotherapy has revolutionized and opened a new paradigm for cancer treatment. In the era of immunotherapy and molecular targeted therapy, precision medicine has gained emphasis, and an early response assessment...
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SOCS3 Attenuates DexamethasoneInduced M2 Polarization by DownRegulation of GILZ via ROS- and p38 MAPK-Dependent Pathways

Jeong H, Yoon H, Lee Y, Kim JT, Yang M, Kim G, Jung B, Park SH, Lee CE

Suppressors of cytokine signaling (SOCS) have emerged as potential regulators of macrophage function. We have investigated mechanisms of SOCS3 action on type 2 macrophage (M2) differentiation induced by glucocorticoid using...
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Mast Cells Tryptase Promotes Intestinal Fibrosis in Natural Decellularized Intestinal Scaffolds

Wan J, Wu T, Liu Y, Yang M, Fichna J, Guo Y, Yin L, Chen C

BACKGROUND: Standard two-dimensional (2D) culture has confirmed the mechanism of mast cells (MCs) in the pathogenesis of inflammatory bowel disease (IBD), but the regulation of signaling responses of MCs may...
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Genome-Wide Association Analysis to Search for New Loci Associated with Lifelong Premature Ejaculation Risk in Chinese Male Han Population

Wang F, Luo D, Chen J, Pan C, Wang Z, Fu H, Xu J, Yang M, Mo S, Zhuang L, Ye L, Wang W

Purpose: Genetic factors play an indispensable role in the pathogenesis of lifelong premature ejaculation (LPE). The susceptibility genes/SNPs that have been discovered are very limited and can only explain part...
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Validation of the Thyrotoxicosis-associated Insomnia Model Induced by Thyroxine through Sympathetic Stimulation: Face, Construct and Predictive Perspectives

Ai Z, He H, Wang T, Chen L, Huang C, Chen C, Xu P, Zhu G, Yang M, Song Y, Su D

  • KMID: 2524036
  • Exp Neurobiol.
  • 2021 Dec;30(6):387-400.
  • doi: 10.5607/en21023
Insomnia has become a common central nervous system disease. At present, the pathogenesis of insomnia is not clear. Animal models can help us understand the pathogenesis of the disease and...
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Objective Quantitation of EGFR Protein Levels using Quantitative Dot Blot Method for the Prognosis of Gastric Cancer Patients

Xin L, Tang F, Song B, Yang M, Zhang J

Purpose: An underlying factor for the failure of several clinical trials of anti-epidermal growth factor receptor (EGFR) therapies is the lack of an effective method to identify patients who overexpress...
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Interleukin-22 Attenuates Acute Pancreatitis-Associated Intestinal Mucosa Injury in Mice via STAT3 Activation

Bai J, Bai J, Yang M

Background/Aims: Interleukin-22 (IL-22) is an important cytokine maintaining homeostasis at barrier surfaces. In this study, the role of IL-22 in acute pancreatitis-associated intestinal injury was further explored. Methods: Severe acute pancreatitis...
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Effects of Virtual Reality Simulation Program Regarding High-risk Neonatal Infection Control on Nursing Students

Yu M, Yang M, Ku B, Mann JS

Purpose Virtual reality simulation can give nursing students a safe clinical experience involving high-risk infants where access to neonatal intensive care units is limited. This study aimed to examine the effects...
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Depression is Associated with Chewing and Swallowing Function among Elderly Vendors in a Conventional Market: A Preliminary Research

Song HJ, Yoon YT, Kim S, Yang M, Lee M

Objective: This study aimed to investigate the level of chewing and swallowing function (CSF) and the factors related to CSF among elderly vendors in a conventional market. Methods: The cross-sectional study...
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Neonatal Diabetes Mellitus Due to KCNJ11 (KIR6.2) Mutation Successfully Treated with Sulfonylurea

Jang S, Yang M, Ahn SY, Sung SI, Chang YS, Park WS

Neonatal diabetes mellitus (NDM) is a rare disease that occurs at less than 6 months of age and is presumably caused by a mutation in the gene that affects pancreatic...
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The prognostic significance of tumor-infiltrating lymphocytes in cervical cancer

He M, Wang Y, Zhang G, Cao K, Yang M, Liu H

Objective: To predict the prognosis of cervical cancer, we constructed a novel model with 5 specific cell types and identified a potential biomarker. Methods: We employed CIBERSORT and xCell method to...
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Mortality and Morbidities according to Time of Birth in Extremely Low Birth Weight Infants

Yang M, Ahn SY, Jo HS, Sung SI, Chang YS, Park WS, KNN

Background: Although the overall quality of high-risk neonatal care has improved recently, there is still concern about a difference in the quality of care when comparing off-hour births and regular-hour...
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Genetic Diversity of Hard Ticks (Acari: Ixodidae) in the South and East Regions of Kazakhstan and Northwestern China

Yang Y, Tong J, Ruan H, Yang M, Sang C, Liu G, Hazihan W, Xu B, Hornok S, Rizabek K, Gulzhan K, Liu Z, Wang Y

To date, there is no report on the genetic diversity of ticks in these regions. A total of 370 representative ticks from the south and east regions of Kazakhstan (SERK)...
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The Roles of Chemokines in Immune Response to Mycobacterial Infection

Paik S, Yang M, Suh HW, Jo EK

Tuberculosis (TB), a global and deadly infectious disease caused by Mycobacterium tuberculosis (Mtb), is manifested with host immune reaction. The balanced regulation between protective immune and pathologic inflammatory responses is...
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Comparison of Respiratory Outcomes between Less Invasive Surfactant Administration and the IntubationSurfactant-Extubation Technique in Premature Infants with Respiratory Distress Syndrome

Kim HS, Kim HH, Yang M, Han YS, Sung SI, Ahn SY, Chang YS, Park WS

Purpose: To compare respiratory outcomes between less invasive surfactant admi nistration (LISA) and the intubation-surfactant-extubation (INSURE) technique in premature infants with respiratory distress syndrome (RDS). Methods: We performed a retrospective medical...
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ary Characteristics and Needs for Community Kitchens among Young Adults of Single-person Households in Seoul according to the Cooking Attitude

Yang M, Asano K, Kim N, Yoon J

Objectives: This study examined the dietary characteristics and needs for community kitchens among young adults of single-person households in Seoul according to the cooking attitude. Methods: During April 2018, an online...
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Miliaria Crystallina-like Eruption of Acute Graft-versus-host-disease after Liver Transplantation

Bae K, Shin K, Yang M, Lee WK, Kim T, Kim HS, Ko HC, Kim BS, Kim MB, Kim Wi

  • KMID: 2503027
  • Korean J Dermatol.
  • 2020 Jun;58(5):340-343.
Acute graft-versus-host disease (GVHD) is a common complication associated with bone marrow transplantation. In the rare cases where it occurs after solid organ transplantation, including that of the liver, pancreas,...
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Driving pressure guided ventilation

Ahn HJ, Park M, Kim JA, Yang M, Yoon S, Kim BR, Bahk JH, Oh YJ, Lee EH

Protective ventilation is a prevailing ventilatory strategy these days and is comprised of small tidal volume, limited inspiratory pressure, and application of positive end-expiratory pressure (PEEP). However, several retrospective studies...
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Development and Validation of a Novel Warfarin Dosing Algorithm for Korean Patients With VKORC1 1173C

Cho EH, Lee K, Yang M, Choi R, Baek SY, Sohn I, Kim JS, On YK, Bang OY, Cho HJ, Lee SY

BACKGROUND: Differences in the performance of suggested warfarin dosing algorithms among different ethnicities and genotypes have been reported; this necessitates the development of an algorithm with enhanced performance for specific...
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Erratum: Analysis of Tau Protein Expression in Predicting Pathological Complete Response to Neoadjuvant Chemotherapy in Different Molecular Subtypes of Breast Cancer

Lei C, Yang C, Xia B, Ji F, Zhang Y, Gao H, Xiong Q, Lin Y, Zhuang X, Zhang L, Zhu T, Cheng M, Yang M, Wang K

This corrects the article “Analysis of Tau Protein Expression in Predicting Pathological Complete Response to Neoadjuvant Chemotherapy in Different Molecular Subtypes of Breast Cancer” in volume 23 on page 47. This...
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