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RNA interference mediated suppression of TRPV6 inhibits the progression of prostate cancer in vitro by modulating cathepsin B and MMP9 expression

Kim DY, Kim SH, Yang EK

Purpose: The transient receptor potential vanilloid 6 (TRPV6) channel is overexpressed in prostate cancer and its silencing is known to inhibit the growth of LNCaP cells. However, the role of...
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Changes of Tissue Inhibitors of Metalloproteinase Expression by Transient Receptor Potential Melastatin-Subfamily Member 7 Suppression in Renal Cancer Cells

Kim DY, Kim SH, Yang EK

Purpose: Recent studies have shown that transient receptor potential melastatin-subfamily member 7 (TRPM7) may enhance cancer cell growth, migration and invasion of human renal cell carcinoma (RCC). We investigated how...
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Histone deacetylase inhibitor, CG200745, attenuates cardiac hypertrophy and fibrosis in DOCA-induced hypertensive rats

Lee E, Song MJ, Lee HA, Kang SH, Kim M, Yang EK, Lee DY, Ro S, Cho JM, Kim I

CG200745 is a novel inhibitor of histone deacetylases (HDACs), initially developed for treatment of various hematological and solid cancers. Because it is water-soluble, it can be administered orally. We hypothesized...
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Is the Expression of p53, c-erb-B2 and Ki-67 Influence the Prognosis of the Non-muscle Invasive Urothelial Bladder Cancer?

Kang SH, Jung HJ, Yang EK, Park JS, Oh HK, Kim DY

PURPOSE: The immunohistochemial markers can be used to predict prognosis more accurately for several cancers. In non-muscle invasive urothelial carcinoma, p53, c-erb-B2 and Ki-67 are applicable. We investigated a retrospective...
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Hemodialysis Patients' Experience of Adapting to Dietary Therapy

Yang EK, Kim IO

PURPOSE: The purpose of this study was to explore the meaning of the experience of adapting to the dietary treatment for hemodialysis patients. METHODS: The data were collected through in-depth interviews...
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17Beta-Estradiol Inhibits Calcium-Activated Potassium Channel Expressions in Rat Whole Bladder

Kim DY, Yang EK

PURPOSE: To investigate the effect of estrogen on the expression of calcium-activated potassium (KCa) channels in an overactive bladder rat model. To this end, mRNA and protein levels of KCa...
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Bee Venom Exerts Neuroprotective Effects on Neuronal Cells and Astrocytes under Hypoxic Conditions Through MAPK Signaling Pathways

Lee EJ, Kim BJ, Jeong JE, Chung HL, Yang EK, Kim WT

PURPOSE: Hypoxic-ischemic brain injuries influence the mechanisms of signal transduction, including mitogen-activated protein kinase (MAPK) that regulates gene expression through transcription factor activity. Several attempts have been made to use...
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Effects of Knowledge and Recognition of Alcohol Use during Pregnancy on Actual Alcohol Use during Pregnancy

Kim IO, Jeong GC, Yang EK

PURPOSE: The purpose of this study was to explore the influence in a planned pregnancy of alcohol related family variables, knowledge and recognition of the effects of alcohol use during...
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Influencing Factors on Smoking Cessation Motivation of Adult Males

Yoon YM, Yang EK, Shin SR

  • KMID: 2298305
  • Korean J Adult Nurs.
  • 2012 Oct;24(5):520-530.
PURPOSE: This research analyzed the different factors that influenced smoking cessation motivation. METHODS: Subjects were both current and past male adult smokers. Data collection was conducted in four small businesses in...
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Absorbable Guided Bone Regeneration Membrane Fabricated from Dehydrothermal Treated Porcine Collagen

Pang KM, Choung HW, Kim SP, Yang EK, Kim KH, Kim SM, Kim MJ, Jahng JW, Lee JH

  • KMID: 1449184
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Mar;33(2):112-119.
PURPOSE: Collagen membranes are used extensively as bioabsorbable barriers in guided bone regeneration. However, collagen has different effects on tissue restoration depending on the type, structure, degree of cross-linking and...
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Genetic association of angiogenesis- and hypoxia-related gene polymorphisms with osteonecrosis of the femoral head

Hong JM, Kim TH, Kim HJ, Park EK, Yang EK, Kim SY

Multiple factors have been implicated in the development of osteonecrosis of the femoral head (ONFH). In particular, non-traumatic ONFH is directly or indirectly related to injury of the vascular supply...
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Antimicrobial Effects of Nano-Silver Gauze against Common Bacterial Isolates

Lee SM, Yang EK, Lee EY, Kim YD, Chang CL

  • KMID: 2307595
  • Korean J Nosocomial Infect Control.
  • 2006 Dec;11(2):87-91.
BACKGROUND: Silver has been used for disinfection and sterilization. We aimed to confirm the in-vitro antibacterial effects of nanocrystalline silver-coated gauze. METHODS: Fourteen clinical isolates each of Escherichia coli and...
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The Effect of Various Methods of Cross-linking in Type I Collagen Scaffold on Cartilage Regeneration

Son DG, Lim JJ, Sohn K, Yang EK

  • KMID: 2203345
  • J Korean Soc Plast Reconstr Surg.
  • 2006 Nov;33(6):723-731.
PURPOSE: Collagen is the principal structural biomolecule in cartilage extracellular matrix, which makes it a logical target for cartilage engineering. In this study, porous type I collagen scaffolds were cross-linked...
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Evaluation of Automatic Acid-Fast Bacilli Stainer AT-2000F

Kim SY, Yang EK, Kim YJ, Lee SM, Lee EY, Park YK, Bai GH, Chang CL

  • KMID: 2224723
  • Korean J Clin Microbiol.
  • 2006 Oct;9(2):115-118.
BACKGROUND: Sputum smear microscopy is rapid, economic, and useful to detect patients with transmittable tuberculosis, albeit laborious. We aimed to evaluate the usefulness of an automated acid-fast bacilli stainer, which...
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Involvement of ERK1/2 and JNK Pathways in 17beta-estradiol Induced Kir6.2 and SK2 Upregulation in Rat Osteoblast-like Cells

Kim JW, Yang EK

  • KMID: 1587398
  • Korean J Physiol Pharmacol.
  • 2006 Aug;10(4):199-205.
The functional expression of potassium (K+) channels has electrophysiologically been studied in bone cells from several species, however, their identity and regulation of gene expressions in bone cells are not...
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Altered Expressions of Calcium-Activated Potassium Channel and Connexin in Bladder Mucosae of Stress Urinary Incontinence Patients with Overactive Bladder Symptoms

Kim DY, Kim JW, Yang EK

PURPOSE: The aim of this study was to examine how the mRNA and protein levels of calcium activated Kchannel (K(Ca)) and connexin (Cx) change in association with overactive bladder in...
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Downregulation of Peroxisome Proliferator-Activated Receptor (PPAR)alpha, PPARgamma, and Phosphoglycerate Mutase 2 in Prostate Cancer

Cho HJ, Kim DY, Kim JW, Yoo TK, Yang EK

PURPOSE: To evaluate whether factors related to lipid and glucose metabolism have a potential role in the progression of prostate cancer, we measured the mRNA levels of the peroxisome proliferator-activated...
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Development of biocompatible dressing material made of collagen and amniotic membrane and wound healing experiment in rat

Ahn KM, Lee JH, Lee UL, Lee JH, Lee JW, Kim SP, Yang EK, Kim KH

  • KMID: 1567694
  • J Korean Assoc Oral Maxillofac Surg.
  • 2006 Jun;32(3):189-199.
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Alterations in Calcium-Activated Potassium Channel Expressions in Human Prostate Cancer

Kim DY, Yang EK, Kim JW

PURPOSE: Recent studies have shown that potassium (K+) and sodium channels are involved in prostate cell growth. However, a great many of the studies have been done in prostate cancer...
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Antimicrobial Activities of Arbekacin against Recent Isolates of Staphylococcus aureus in Korean Hospitals

Lee SM, Song EJ, Yang EK, Bae IK, Jeong SH, Kim JM, Lee EY, Chang CL

  • KMID: 2146985
  • Korean J Clin Microbiol.
  • 2006 Apr;9(1):13-17.
BACKGROUND: As clinical isolates of Staphylococcus aureus with reduced inhibition zone of arbekacin in disk diffusion susceptibility tests are observed frequently, we examined their susceptibility to the antibiotic by comparing...
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